EGFR expression in circulating tumor cells from high-grade metastatic soft tissue sarcomas

References

• Singer S, Demetri GD, Baldini EH, Fletcher CD. Management of soft-tissue sarcomas: an overview and update. Lancet Oncol. 2000;1:75–85. doi:10.1016/S1470-2045(00)00016-4. PMID:11905672
   PubMedGoogle Scholar
• Mackall CL, Meltzer PS, Helman LJ. Focus on sarcomas. Cancer Cell. 2002;2(3):175–8. doi:10.1016/S1535-6108(02)00132-0. PMID:12242149
   PubMed Web of Science ®Google Scholar
• Klein CA. Parallel progression of primary tumours and metastases. Nat Rev Cancer. 2009;9(4):302–12. doi:10.1038/nrc2627. PMID:19308069
   PubMed Web of Science ®Google Scholar
• Paterlini-Brechot P, Benali NL. Circulating tumor cells (CTC) detection: clinical impact and future directions. Cancer Lett. 2007;253(2):180–204. doi:10.1016/j.canlet.2006.12.014. PMID:17314005
   PubMed Web of Science ®Google Scholar
• Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, et al. EMT and dissemination precede pancreatic tumor formation. Cell. 2012;148(1–2):349–61. doi:10.1016/j.cell.2011.11.025. PMID:22265420
   PubMed Web of Science ®Google Scholar
• Chang L, Asatrian G, Dry SM, James AW. Circulating tumor cells in sarcomas: a brief review. Med Oncol Northwood Lond Engl. 2015;32(1):430. doi:10.1007/s12032-014-0430-9.
   PubMed Web of Science ®Google Scholar
• Vona G, Sabile A, Louha M, Sitruk V, Romana S, Schütze K, Capron F, Franco D, Pazzagli M, Vekemans M, et al. Isolation by size of epithelial tumor cells. Am J Pathol. 2000;156(1):57–63. doi:10.1016/S0002-9440(10)64706-2. PMID:10623654
   PubMed Web of Science ®Google Scholar
• Khoja L, Backen A, Sloane R, Menasce L, Ryder D, Krebs M, Board R, Clack G, Hughes A, Blackhall F, et al. A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker. Br J Cancer. 2012;106(3):508–16. doi:10.1038/bjc.2011.545. PMID:22187035
   PubMed Web of Science ®Google Scholar
• Lucci A, Hall CS, Lodhi AK, Bhattacharyya A, Anderson AE, Xiao L, Bedrosian I, Kuerer HM, Krishnamurthy S. Circulating tumour cells in non-metastatic breast cancer: a prospective study. Lancet Oncol. 2012;13(7):688–95. doi:10.1016/S1470-2045(12)70209-7. PMID:22677156
   PubMed Web of Science ®Google Scholar
• Knisely WH, Mahaley MS. Relationship between size and distribution of spontaneous metastases and three sizes of intravenously injected particles of VX2 carcinoma. Cancer Res. 1958;18(8 Part 1):900–5. PMID:13573362
   PubMed Web of Science ®Google Scholar
• Brandt B, Junker R, Griwatz C, Heidl S, Brinkmann O, Semjonow A, Assmann G, Zänker KS. Isolation of prostate-derived single cells and cell clusters from human peripheral blood. Cancer Res. 1996;56(20):4556–61. PMID:8840959
   PubMed Web of Science ®Google Scholar
• Molnar B, Ladanyi A, Tanko L, Sréter L, Tulassay Z. Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients. Clin Cancer Res Off J Am Assoc Cancer Res. 2001;7(12):4080–5.
   PubMed Web of Science ®Google Scholar
• Kats-Ugurlu G, Roodink I, de Weijert M, Tiemessen D, Maass C, Verrijp K, van der Laak J, de Waal R, Mulders P, Oosterwijk E, et al. Circulating tumour tissue fragments in patients with pulmonary metastasis of clear cell renal cell carcinoma. J Pathol. 2009;219(3):287–93. doi:10.1002/path.2613. PMID:19731255
   PubMed Web of Science ®Google Scholar
• Hou J-M, Krebs MG, Lancashire L, Sloane R, Backen A, Swain RK, et al. Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2012;30(5):525–32. doi:10.1200/JCO.2010.33.3716.
   PubMed Web of Science ®Google Scholar
• Krebs MG, Hou J-M, Sloane R, Lancashire L, Priest L, Nonaka D, Ward TH, Backen A, Clack G, Hughes A, et al. Analysis of circulating tumor cells in patients with non-small cell lung cancer using epithelial marker-dependent and -independent approaches. J Thorac Oncol Off Publ Int Assoc Study Lung Cancer. 2012;7(2):306–15.
   Google Scholar
• Fanelli MF, Oliveira TB, Braun AC, Corassa M, Abdallah EA, Nicolau UR, da Silva Alves V, Garcia D, Calsavara VF, Kowalski LP, et al. Evaluation of incidence, significance, and prognostic role of circulating tumor microemboli and transforming growth factor-β receptor I in head and neck cancer. Head Neck. 2017;39(11):2283–2292 doi:10.1002/hed.24899. PMID:28815787
   PubMed Web of Science ®Google Scholar
• Chen J-Y, Tsai W-S, Shao H-J, Wu J-C, Lai J-M, Lu S-H, Hung TF, Yang CT, Wu LC, Chen JS, et al. Sensitive and specific biomimetic lipid coated microfluidics to isolate viable circulating tumor cells and microemboli for cancer detection. PloS One. 2016;11(3):e0149633. doi:10.1371/journal.pone.0149633. PMID:26938471
   PubMed Web of Science ®Google Scholar
• Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2010;141(7):1117–34. doi:10.1016/j.cell.2010.06.011. PMID:20602996
   PubMed Web of Science ®Google Scholar
• Egloff AM, Grandis JR. Targeting epidermal growth factor receptor and SRC pathways in head and neck cancer. Semin Oncol. 2008;35(3):286–97. doi:10.1053/j.seminoncol.2008.03.008. PMID:18544443
   PubMed Web of Science ®Google Scholar
• Lee CS, Redshaw A, Boag G. Epidermal growth factor receptor immunoreactivity in human laryngeal squamous cell carcinoma. Pathology (Phila). 1997;29(3):251–4.
   Google Scholar
• Grandis JR, Chakraborty A, Zeng Q, Melhem MF, Tweardy DJ. Downmodulation of TGF-alpha protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells. J Cell Biochem. 1998;69(1):55–62. doi:10.1002/(SICI)1097-4644(19980401)69:1%3c55::AID-JCB6%3e3.0.CO;2-U. PMID:9513046
   PubMed Web of Science ®Google Scholar
• Adjei AA, Rowinsky EK. Novel anticancer agents in clinical development. Cancer Biol Ther. 2003;2(4 Suppl 1):S5–15. PMID:14508076
   PubMed Web of Science ®Google Scholar
• Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer. 2005;5(5):341–54. doi:10.1038/nrc1609. PMID:15864276
   PubMed Web of Science ®Google Scholar
• Chinen LTD, Mello CAL, Abdallah EA, Ocea LM, Buim ME, Breve NM, et al. Isolation, detection, and immunomorphological characterization of circulating tumor cells (CTCs) from patients with different types of sarcoma using isolation by size of tumor cells: a window on sarcoma-cell invasion. OncoTargets Ther. 2014;7:1609–17. doi:10.2147/OTT.S62349.
   PubMed Web of Science ®Google Scholar
• Khoja L, Shenjere P, Hodgson C, Hodgetts J, Clack G, Hughes A, Lorigan P, Dive C. Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma. Melanoma Res. 2014;24(1):40–6. doi:10.1097/CMR.0000000000000025. PMID:24201293
   PubMed Web of Science ®Google Scholar
• Lausen B, Schumacher M. Maximally Selected Rank Statistics. Biometrics. 1992;48(1):73. doi:10.2307/2532740.
   Web of Science ®Google Scholar
• Nicolazzo C, Gradilone A. Significance of circulating tumor cells in soft tissue sarcoma. Anal Cell Pathol Amst. 2015;2015:697395. PMID:26167450
   PubMedGoogle Scholar
• Long E, Ilie M, Bence C, Butori C, Selva E, Lalvée S, Bonnetaud C, Poissonnet G, Lacour JP, Bahadoran P, et al. High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness. Cancer Med. 2016;5(6):1022–30. doi:10.1002/cam4.661. PMID:26945789
   PubMed Web of Science ®Google Scholar
• Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, et al. Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell. 2014;158(5):1110–22. doi:10.1016/j.cell.2014.07.013. PMID:25171411
   PubMed Web of Science ®Google Scholar
• Carlsson A, Nair VS, Luttgen MS, Keu KV, Horng G, Vasanawala M, et al. Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer. J Thorac Oncol Off Publ Int Assoc Study Lung Cancer. 2014;9(8):1111–9.
   Google Scholar
• Nicholson RI, Gee JM, Harper ME. EGFR and cancer prognosis. Eur J Cancer Oxf Engl 1990. 2001;37 Suppl 4:S9–15.
   PubMed Web of Science ®Google Scholar
• Sato O, Wada T, Kawai A, Yamaguchi U, Makimoto A, Kokai Y, Yamashita T, Chuman H, Beppu Y, Tani Y, et al. Expression of epidermal growth factor receptor, ERBB2 and KIT in adult soft tissue sarcomas: a clinicopathologic study of 281 cases. Cancer. 2005;103(9):1881–90. doi:10.1002/cncr.20986. PMID:15772959
   PubMed Web of Science ®Google Scholar
• Yang J-L, Hannan MT, Russell PJ, Crowe PJ. Expression of HER1/EGFR protein in human soft tissue sarcomas. Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol. 2006;32(4)466–8.
   Google Scholar
• Sannino G, Marchetto A, Kirchner T, Grünewald TGP. Epithelial-to-mesenchymal and mesenchymal-to-epithelial transition in mesenchymal tumors: A paradox in sarcomas? Cancer Res. 2017;77(17):4556–61. doi:10.1158/0008-5472.CAN-17-0032. PMID:28811330
   PubMed Web of Science ®Google Scholar