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Gprc5a-deficiency confers susceptibility to endotoxin-induced acute lung injury via NF-κB pathway

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Pages 1403-1412 | Received 04 Oct 2014, Accepted 05 Jan 2015, Published online: 30 Apr 2015

References

  • Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003; 348:683-93; PMID:12594312; http://dx.doi.org/10.1056/NEJMoa022450
  • Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD. Incidence and outcomes of acute lung injury. N Engl J Med 2005; 353:1685-93; PMID:16236739; http://dx.doi.org/10.1056/NEJMoa050333
  • Brandolini L, Asti C, Ruggieri V, Intilangelo A, Pellegrini L, Chiusaroli R, Caselli GF, Bertini R. Lipopolysaccharide-induced lung injury in mice. II. Evaluation of functional damage in isolated parenchyma strips. Pulm Pharmacol Ther 2000; 13:71-8; PMID:10799284; http://dx.doi.org/10.1006/pupt.2000.0232
  • Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000; 342:1334-49; PMID:10793167; http://dx.doi.org/10.1056/NEJM200005043421806
  • Manicone AM. Role of the pulmonary epithelium and inflammatory signals in acute lung injury. Expert Rev Clin Immunol 2009; 5:63-75; PMID:19885383; http://dx.doi.org/10.1586/1744666X.5.1.63
  • Reddy AJ, Kleeberger SR. Genetic polymorphisms associated with acute lung injury. Pharmacogenomics 2009; 10:1527-39; PMID:19761373; http://dx.doi.org/10.2217/pgs.09.89
  • Jin W, Wang H, Ji Y, Zhu L, Yan W, Qiao L, Yin H. Genetic ablation of Nrf2 enhances susceptibility to acute lung injury after traumatic brain injury in mice. Exp Biol Med 2009; 234:181-9; PMID:19176347; http://dx.doi.org/10.3181/0807-RM-232
  • Meduri GU, Headley S, Kohler G, Stentz F, Tolley E, Umberger R, Leeper K. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest 1995; 107:1062-73; PMID:7705118; http://dx.doi.org/10.1378/chest.107.4.1062
  • Thickett DR, Armstrong L, Millar AB. A role for vascular endothelial growth factor in acute and resolving lung injury. Am J Respir Crit Care Med 2002; 166:1332-7; PMID:12421742; http://dx.doi.org/10.1164/rccm.2105057
  • Prabhakaran P, Ware LB, White KE, Cross MT, Matthay MA, Olman MA. Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol 2003; 285:L20-8; PMID:12730079
  • Pan T, Nielsen LD, Allen MJ, Shannon KM, Shannon JM, Selman M, Mason RJ. Serum SP-D is a marker of lung injury in rats. Am J Physiol Lung Cell Mol Physiol 2002; 282:L824-32; PMID:11880309; http://dx.doi.org/10.1152/ajpcell.00388.2001
  • Kawut SM, Okun J, Shimbo D, Lederer DJ, De Andrade J, Lama V, Shah A, Milstone A, Ware LB, Weinacker A, et al. Soluble p-selectin and the risk of primary graft dysfunction after lung transplantation. Chest 2009; 136:237-44; PMID:19255296; http://dx.doi.org/10.1378/chest.08-2697
  • Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, et al. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med 2006; 12:1286-93; PMID:17086189; http://dx.doi.org/10.1038/nm1494
  • Wang Z, Beach D, Su L, Zhai R, Christiani DC. A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS. Am J Respir Cell Mol Biol 2008; 38:724-32; PMID:18203972; http://dx.doi.org/10.1165/rcmb.2007-0354OC
  • Grigoryev DN, Finigan JH, Hassoun P, Garcia JG. Science review: searching for gene candidates in acute lung injury. Critical care 2004; 8:440-7; PMID:15566614; http://dx.doi.org/10.1186/cc2901
  • Cheng Y, Lotan R. Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor. J Biol Chem 1998; 273:35008-15; PMID:9857033; http://dx.doi.org/10.1074/jbc.273.52.35008
  • Wu Q, Ding W, Mirza A, Van Arsdale T, Wei I, Bishop WR, Basso A, McClanahan T, Luo L, Kirschmeier P, et al. Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target. J Biol Chem 2005; 280:12935-43; PMID:15659406; http://dx.doi.org/10.1074/jbc.M409901200
  • Tao Q, Fujimoto J, Men T, Ye X, Deng J, Lacroix L, Clifford JL, Mao L, Van Pelt CS, Lee JJ, et al. Identification of the retinoic acid-inducible Gprc5a as a new lung tumor suppressor gene. J Natl Cancer Inst 2007; 99:1668-82; PMID:18000218; http://dx.doi.org/10.1093/jnci/djm208
  • Xu J, Tian J, Shapiro SD. Normal lung development in RAIG1-deficient mice despite unique lung epithelium-specific expression. Am J Respir Cell Mol Biol 2005; 32:381-7; PMID:15677768; http://dx.doi.org/10.1165/rcmb.2004-0343OC
  • Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, et al. Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Cancer Prev Res (Phila Pa) 2010; 3:424-37; http://dx.doi.org/10.1158/1940-6207.CAPR-10-0032
  • Haddad JJ. Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells. Biochem Biophys Res Commun 2002; 293:252-7; PMID:12054592; http://dx.doi.org/10.1016/S0006-291X(02)00213-9
  • Matsuda N, Hattori Y, Takahashi Y, Nishihira J, Jesmin S, Kobayashi M, Gando S. Therapeutic effect of in vivo transfection of transcription factor decoy to NF-kappaB on septic lung in mice. Am J Physiol Lung Cell Mol Physiol 2004; 287:L1248-55; PMID:15298852; http://dx.doi.org/10.1152/ajplung.00164.2004
  • Oshikawa K, Sugiyama Y. Gene expression of Toll-like receptors and associated molecules induced by inflammatory stimuli in the primary alveolar macrophage. Biochem Biophys Res Commun 2003; 305:649-55; PMID:12763043; http://dx.doi.org/10.1016/S0006-291X(03)00837-4
  • Koay MA, Gao X, Washington MK, Parman KS, Sadikot RT, Blackwell TS, Christman JW. Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxin. Am J Respir Cell Mol Biol 2002; 26:572-8; PMID:11970909; http://dx.doi.org/10.1165/ajrcmb.26.5.4748
  • Lentsch AB, Czermak BJ, Bless NM, Van Rooijen N, Ward PA. Essential role of alveolar macrophages in intrapulmonary activation of NF-kappaB. Am J Respir Cell Mol Biol 1999; 20:692-8; PMID:10101001; http://dx.doi.org/10.1165/ajrcmb.20.4.3414
  • Cheng DS, Han W, Chen SM, Sherrill TP, Chont M, Park GY, Sheller JR, Polosukhin VV, Christman JW, Yull FE, et al. Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway. J Immunol 2007; 178:6504-13; http://dx.doi.org/10.4049/jimmunol.178.10.6504
  • Rojas M, Woods CR, Mora AL, Xu J, Brigham KL. Endotoxin-induced lung injury in mice: structural, functional, and biochemical responses. Am J Physiol Lung Cell Mol Physiol 2005; 288:L333-41; PMID:15475380; http://dx.doi.org/10.1152/ajplung.00334.2004
  • Matute-Bello G, Frevert CW, Martin TR. Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2008; 295:L379-99; PMID:18621912; http://dx.doi.org/10.1152/ajplung.00010.2008
  • Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med 2009; 15:410-6; PMID:19330007; http://dx.doi.org/10.1038/nm.1946
  • Skerrett SJ, Liggitt HD, Hajjar AM, Ernst RK, Miller SI, Wilson CB. Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin. Am J Physiol Lung Cell Mol Physiol 2004; 287:L143-52; PMID:15047567; http://dx.doi.org/10.1152/ajplung.00030.2004
  • Deng J, Miller SA, Wang HY, Xia W, Wen Y, Zhou BP, Li Y, Lin SY, Hung MC. beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell 2002; 2:323-34; PMID:12398896; http://dx.doi.org/10.1016/S1535-6108(02)00154-X

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