2,190
Views
24
CrossRef citations to date
0
Altmetric
Report

LIF-JAK1-STAT3 signaling delays contact inhibition of human corneal endothelial cells

, , , , , & show all
Pages 1197-1206 | Received 11 Nov 2014, Accepted 23 Jan 2015, Published online: 18 Apr 2015

References

  • Bonanno JA. Identity and regulation of ion transport mechanisms in the corneal endothelium. Prog Retin Eye Res 2003; 22:69–94; PMID:12597924; http://dx.doi.org/10.1016/S1350-9462(02)00059-9
  • Laing RA, Neubauer L, Oak SS, Kayne HL, Leibowitz HM. Evidence for mitosis in the adult corneal endothelium. Ophthalmology 1984; 91:1129–34; PMID:6392976; http://dx.doi.org/10.1016/S0161-6420(84)34176-8
  • Joyce NC. Cell cycle status in human corneal endothelium. Exp Eye Res 2005; 81:629–38; PMID:16054624; http://dx.doi.org/10.1016/j.exer.2005.06.012
  • DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A 1997; 94:7245–50; PMID:9207076; http://dx.doi.org/10.1073/pnas.94.14.7245
  • Sherr CJ, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995; 9:1149–63; PMID:7758941; http://dx.doi.org/10.1101/gad.9.10.1149
  • Engelmann K, Bohnke M, Friedl P. Isolation and long-term cultivation of human corneal endothelial cells. Invest Ophthalmol Vis Sci 1988; 29:1656–62; PMID:3182201
  • Lee JG, Kay EP. FGF-2-mediated signal transduction during endothelial mesenchymal transformation in corneal endothelial cells. Exp Eye Res 2006; 83:1309–16; PMID:16769055; http://dx.doi.org/10.1016/j.exer.2006.04.007
  • Li W, Sabater AL, Chen YT, Hayashida Y, Chen SY, He H, Tseng SC. A novel method of isolation, preservation, and expansion of human corneal endothelial cells. Invest Ophthalmol Vis Sci 2007; 48:614–20; PMID:17251457; http://dx.doi.org/10.1167/iovs.06-1126
  • Zhu YT, Hayashida Y, Kheirkhah A, He H, Chen SY, Tseng SC. Characterization and comparison of intercellular adherent junctions expressed by human corneal endothelial cells in vivo and in vitro. Invest Ophthalmol Vis Sci 2008; 49:3879–86; PMID:18502989; http://dx.doi.org/10.1167/iovs.08-1693
  • Zhu YT, Chen HC, Chen SY, Tseng SC. Nuclear p120 catenin unlocks mitotic block of contact-inhibited human corneal endothelial monolayers without disrupting adherent junctions. J Cell Sci 2012; 125:3636–48; PMID:22505615; http://dx.doi.org/10.1242/jcs.103267
  • Chen HC, Zhu YT, Chen SY, Tseng SC. Selective activation of p120ctn-Kaiso signaling to unlock contact inhibition of ARPE-19 cells without epithelial-mesenchymal transition. PLoS One 2012; 7:e36864; PMID:22590627; http://dx.doi.org/10.1371/journal.pone.0036864
  • Zhu YT, Han B, Li F, Chen SY, Tighe S, Zhang S, Tseng SC. Knockdown of both p120 catenin and Kaiso promotes expansion of human corneal endothelial monolayers via RhoA-ROCK-noncanonical BMP-NFkappaB pathway. Invest Ophthalmol Vis Sci 2014; 55:1509–18; PMID:24474278; http://dx.doi.org/10.1167/iovs.13-13633
  • Li GG, Chen SY, Xie HT, Zhu YT, Tseng SC. Angiogenesis potential of human limbal stromal niche cells. Invest Ophthalmol Vis Sci 2012; 53:3357–67; PMID:22538425; http://dx.doi.org/10.1167/iovs.11-9414
  • Li GG, Zhu YT, Xie HT, Chen SY, Tseng SC. Mesenchymal stem cells derived from human limbal niche cells. Invest Ophthalmol Vis Sci 2012; 53:5686–97; PMID:22836771; http://dx.doi.org/10.1167/iovs.12-10300
  • Xie HT, Chen SY, Li GG, Tseng SC. Isolation and expansion of human limbal stromal niche cells. Invest Ophthalmol Vis Sci 2012; 53:279–86; PMID:22167096; http://dx.doi.org/10.1167/iovs.11-8441
  • Zhu YT, Li F, Han B, Tighe S, Zhang S, Chen SY, Liu X, Tseng SC. Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells. J Cell Biol 2014; 206:799–811; PMID:25202030; http://dx.doi.org/10.1083/jcb.201404032
  • Hirai H, Karian P, Kikyo N. Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor. Biochem J 2011; 438:11–23; PMID:21793804; http://dx.doi.org/10.1042/BJ20102152
  • Tang Y, Tian XC. JAK-STAT3 and somatic cell reprogramming. JAKSTAT 2013; 2:e24935; PMID:24470976
  • Matsuda T, Nakamura T, Nakao K, Arai T, Katsuki M, Heike T, Yokota T. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 1999; 18:4261–9; PMID:10428964; http://dx.doi.org/10.1093/emboj/18.15.4261
  • Forrai A, Boyle K, Hart AH, Hartley L, Rakar S, Willson TA, Simpson KM, Roberts AW, Alexander WS, Voss AK, et al. Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells. Stem Cells 2006; 24:604–14; PMID:16123385; http://dx.doi.org/10.1634/stemcells.2005-0323
  • O'Brien JJ, Nathanson NM. Retrograde activation of STAT3 by leukemia inhibitory factor in sympathetic neurons. J Neurochem 2007; 103:288–302; PMID:17608645
  • Shankland SJ, Floege J, Thomas SE, Nangaku M, Hugo C, Pippin J, Henne K, Hockenberry DM, Johnson RJ, Couser WG. Cyclin kinase inhibitors are increased during experimental membranous nephropathy: potential role in limiting glomerular epithelial cell proliferation in vivo. Kidney Int 1997; 52:404–13; PMID:9263996; http://dx.doi.org/10.1038/ki.1997.347
  • Takahashi H, Toyoda M, Birumachi J, Horie A, Uyama T, Miyado K, Matsumoto K, Saito H, Umezawa A. Shortening of human cell life span by induction of p16ink4a through the platelet-derived growth factor receptor beta. J Cell Physiol 2009; 221:335–42; PMID:19582773; http://dx.doi.org/10.1002/jcp.21860
  • Sun P. Contact inhibition against senescence. Oncotarget 2014; 5:7212–3; PMID:25277173
  • Leontieva OV, Demidenko ZN, Blagosklonny MV. Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program. Proc Natl Acad Sci U S A 2014; 111:8832–7; PMID:24889617; http://dx.doi.org/10.1073/pnas.1405723111
  • McAlister JC, Joyce NC, Harris DL, Ali RR, Larkin DF. Induction of replication in human corneal endothelial cells by E2F2 transcription factor cDNA transfer. Invest Ophthalmol Vis Sci 2005; 46:3597–603; PMID:16186339; http://dx.doi.org/10.1167/iovs.04-0551
  • Fukada T, Hibi M, Yamanaka Y, Takahashi-Tezuka M, Fujitani Y, Yamaguchi T, Nakajima K, Hirano T. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity 1996; 5:449–60; PMID:8934572; http://dx.doi.org/10.1016/S1074-7613(00)80501-4
  • Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, Ciliberto G, Moscinski L, Fernandez-Luna JL, Nunez G, et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 1999; 10:105–15; PMID:10023775; http://dx.doi.org/10.1016/S1074-7613(00)80011-4
  • Nichane M, Ren X, Bellefroid EJ. Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specification. EMBO J 2010; 29:55–67; PMID:19851287; http://dx.doi.org/10.1038/emboj.2009.313
  • Joyce NC, Harris DL, Zieske JD. Mitotic inhibition of corneal endothelium in neonatal rats. Invest Ophthalmol Vis Sci 1998; 39:2572–83; PMID:9856767
  • Joyce NC, Harris DL, Mello DM. Mechanisms of mitotic inhibition in corneal endothelium: contact inhibition and TGF-beta2. Invest Ophthalmol Vis Sci 2002; 43:2152–9; PMID:12091410
  • Joyce NC, Harris DL. Decreasing expression of the G1-phase inhibitors, p21Cip1 and p16INK4a, promotes division of corneal endothelial cells from older donors. Mol Vis 2010; 16:897–906; PMID:20508865
  • Song Z, Wang Y, Xie L, Zang X, Yin H. Expression of senescence-related genes in human corneal endothelial cells. Mol Vis 2008; 14:161–70; PMID:18334933

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.