Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis

References

• Fededa JP, Gerlich DW. Molecular control of animal cell cytokinesis. Nat Cell Biol 2012; 14:440–47; PMID:22552143; https://doi.org/10.1038/ncb2482
   PubMed Web of Science ®Google Scholar
• Normand G, King RW. Understanding cytokinesis failure. Adv Exp Med Biol 2010; 676:27–55; PMID:20687468; https://doi.org/10.1007/978-1-4419-6199-0_3
   PubMed Web of Science ®Google Scholar
• Glotzer M. The 3Ms of central spindle assembly: microtubules, motors and MAPs. Nat Rev Mol Cell Biol 2009;10:9–20; PMID:19197328; https://doi.org/10.1038/nrm2609
   PubMed Web of Science ®Google Scholar
• Adams RR, Tavares AA, Salzberg A, Bellen HJ, Glover DM. pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis. Genes Dev 1998; 15:1483–94; PMID:9585508; https://doi.org/10.1101/gad.12.10.1483
   PubMedGoogle Scholar
• Raich WB, Moran AN, Rothman JH, Hardin J. Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin-like protein ZEN-4. Mol Biol Cell 1998; 9:2037–49; PMID:9693365; https://doi.org/10.1091/mbc.9.8.2037
   PubMed Web of Science ®Google Scholar
• Nislow C, Lombillo VA, Kuriyama R, McIntosh JR. A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles. Nature 1992; 359:543–7; PMID:1406973; https://doi.org/10.1038/359543a0
   PubMed Web of Science ®Google Scholar
• Sellitto C, Kuriyama R. Distribution of a matrix component of the midbody during the cell cycle in Chinese hamster ovary cells. J Cell Biol 1988; 106:431–9; PMID:2448315
   PubMed Web of Science ®Google Scholar
• Kuriyama R, Gustus C, Terada Y, Uetake Y, Matuliene J. CHO1, a mammalian kinesin-like protein, interacts with F-actin and is involved in the terminal phase of cytokinesis. J Cell Biol 2002; 156:783–90; PMID:11877456; https://doi.org/10.1083/jcb.200109090
   PubMed Web of Science ®Google Scholar
• Matuliene J, Kuriyama R. Role of the midbody matrix in cytokinesis: RNAi and genetic rescue analysis of the mammalian motor protein CHO1. Mol Biol Cell 2004;15:3083–94; PMID:15075367; https://doi.org/10.1091/mbc.E03-12-0888
   PubMed Web of Science ®Google Scholar
• Nishimura Y, Yonemura S. Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis. J Cell Sci 2006; 119:104–14; PMID:16352658; https://doi.org/10.1242/jcs.02737
   PubMed Web of Science ®Google Scholar
• Yüce O, Piekny A, Glotzer M. An ECT2-centralspindlin complex regulates the localization and function of RhoA. J Cell Biol 2005; 170:571–82; PMID:16103226; https://doi.org/10.1083/jcb.200501097
   PubMed Web of Science ®Google Scholar
• Matuliene J, Kuriyama R. Kinesin-like protein CHO1 is required for the formation of midbody matrix and the completion of cytokinesis in mammalian cells. Mol Biol Cell 2002; 13:1832–45; PMID:12058052; https://doi.org/10.1091/mbc.01-10-0504
   PubMed Web of Science ®Google Scholar
• Kaji N, Ohashi K, Shuin M, Niwa R, Uemura T, Mizuno, K. Cell cycle-associated changes in Slingshot phosphatase activity and roles in cytokinesis in animal cells. J Biol Chem 2003; 278:33450–55; PMID:12807904; https://doi.org/10.1074/jbc.M305802200
   PubMedGoogle Scholar
• Kaji N, Muramoto A, Mizuno K. LIM kinase-mediated cofilin phosphorylation during mitosis is required for precise spindle positioning. J Biol Chem 2008; 283:4983–92; PMID:18079118; https://doi.org/10.1074/jbc.M708644200
   PubMed Web of Science ®Google Scholar
• Amano T, Kaji N, Ohashi K, Mizuno K. Mitosis-specific activation of LIM motif-containing protein kinase and roles of cofilin phosphorylation and dephosphorylation in mitosis. J Biol Chem 2002; 277:22093–102; PMID:11925442; https://doi.org/10.1074/jbc.M201444200
   PubMed Web of Science ®Google Scholar
• Khodjakov A, Rieder, CL. Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression. J Cell Biol 2001; 153:237–42; PMID:11285289; https://doi.org/10.1083/jcb.153.1.237
   PubMed Web of Science ®Google Scholar
• Piel M, Nordberg J, Euteneuer U, Bornens M. Centrosome-dependent exit of cytokinesis in animal cells. Science 2001; 291:1550–3; PMID:11222861; https://doi.org/10.1126/science.1057330
   PubMed Web of Science ®Google Scholar
• Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y, et al. Cdk1/Erk2-and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Dev Cell 2005; 9: 477–88; PMID:16198290; https://doi.org/10.1016/j.devcel.2005.09.003
   PubMed Web of Science ®Google Scholar
• Pan D. The hippo signaling pathway in development and cancer. Dev Cell 2010; 19:491–505; PMID:20951342; https://doi.org/10.1016/j.devcel.2010.09.011
   PubMed Web of Science ®Google Scholar
• Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M. A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. Genes Dev 2006; 20:2687–700; PMID:17015431; https://doi.org/10.1101/gad.1447006
   PubMed Web of Science ®Google Scholar
• Toji S, Yabuta N, Hosomi T, Nishihara S, Kobayashi T, Suzuki S, Tamai K, Nojima H. The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase. Genes Cells 2004; 9:383–97; PMID:15147269; https://doi.org/10.1111/j.1356-9597.2004.00732.x
   PubMed Web of Science ®Google Scholar
• Yabuta N, Mukai S, Okada N, Aylon Y, Nojima H. The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis. Cell Cycle 2011; 10: 2724–36; PMID:21822051; https://doi.org/10.4161/cc.10.16.16873
   PubMed Web of Science ®Google Scholar
• Yabuta N, Okada N, Ito A, Hosomi T, Nishihara S, Sasayama Y, Fujimori A, Okuzaki D, Zhao H, Ikawa M, et al. Lats2 is an essential mitotic regulator required for the coordination of cell division. J Biol Chem 2007; 29:19259–71; PMID:17478426; https://doi.org/10.1074/jbc.M608562200
   PubMedGoogle Scholar
• Nishiyama Y, Hirota T, Morisaki T, Hara T, Marumoto T, Iida S, Makino K, Yamamoto H, Hiraoka T, Kitamura N, et al. A human homolog of Drosophila warts tumor suppressor, h-warts, localized to mitotic apparatus and specifically phosphorylated during mitosis. FEBS Lett 1999; 459:159–65; PMID:10518011; https://doi.org/10.1016/S0014-5793(99)01224-7
   PubMed Web of Science ®Google Scholar
• Yabuta N, Mukai S, Okamoto A, Okuzaki D, Suzuki H, Torigata K, Yoshida K, Okada N, Miura D, Ito A, et al. N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability. J Cell Sci 2013; 126: 508–20; PMID:23230145; https://doi.org/10.1242/jcs.113431
   PubMed Web of Science ®Google Scholar
• Yang X, Yu K, Hao Y, Li DM, Stewart R, Insogna KL, Xu T. LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1. Nat Cell Biol 2004; 6:609–17; PMID:15220930; https://doi.org/10.1038/ncb1140
   PubMed Web of Science ®Google Scholar
• Ganem NJ, Cornils H, Chiu SY, O'Rourke KP, Arnaud J, Yimlamai D, Théry M, Camargo FD, Pellman D. Cytokinesis failure triggers hippo tumor suppressor pathway activation. Cell 2014;158:833–48; PMID:25126788; https://doi.org/10.1038/nrc3824
   PubMed Web of Science ®Google Scholar
• Douglas ME, Davies T, Joseph N, Mishima M. Aurora B and 14-3-3 coordinately regulate clustering of centralspindlin during cytokinesis. Curr Biol 2010; 20:927–33; PMID:20451386; https://doi.org/10.1016/j.cub.2010.03.055
   PubMed Web of Science ®Google Scholar
• Joseph N, Hutterer A, Poser I, Mishima M. ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration. EMBO J 2012; 31:2604–14; PMID:22580824; https://doi.org/10.1038/emboj.2012.139
   PubMed Web of Science ®Google Scholar
• Guse A, Mishima M, Glotzer M. Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis. Curr Biol 2005; 15:778–86; PMID:15854913; https://doi.org/10.1016/j.cub.2005.03.041
   PubMed Web of Science ®Google Scholar
• Mishima M, Kaitna S, Glotzer M. Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell 2002; 2:41–54; PMID:11782313; https://doi.org/10.1016/S1534-5807(01)00110-1
   PubMed Web of Science ®Google Scholar
• Chakrabarti R, Jones JL, Oelschlager DK, Tapia T, Tousson A, Grizzle WE. Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis. Cell Cycle 2007; 6:2944–52; PMID:18000399; https://doi.org/10.4161/cc.6.23.4957
   PubMed Web of Science ®Google Scholar
• Ritchey L, Ottman R, Roumanos M, Chakrabarti R. A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic process. Cell Cycle 2012; 11: 296–309; PMID:22214762; https://doi.org/10.4161/cc.11.2.18734
   PubMed Web of Science ®Google Scholar
• Minoshima Y, Kawashima T, Hirose K, Tonozuka Y, Kawajiri A, Bao YC, Deng X, Tatsuka M, Narumiya S, May WS Jr, et al. Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell 2003; 4:549–60; PMID:12689593; https://doi.org/10.1016/S1534-5807(03)00089-3
   PubMed Web of Science ®Google Scholar
• Wang W, Chen L, Ding Y, Jin J, Liao K. Centrosome separation driven by actin-microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin. J Cell Sci 2008; 121:1334–43; PMID:18388321; https://doi.org/10.1242/jcs.018176
   PubMedGoogle Scholar
• Wada K, Itoga K, Okano T, Yonemura S, Sasaki H. Hippo pathway regulation by cell morphology and stress fibers. Development 2011; 138:3907–14; PMID:21831922; https://doi.org/10.1242/dev.070987
   PubMed Web of Science ®Google Scholar
• Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E. Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction. Nat Cell Biol 2010; 12:1166–76; PMID:21076410; https://doi.org/10.1038/ncb2120
   PubMed Web of Science ®Google Scholar
• Kim M, Kim M, Lee S, Kuninaka S, Saya H, Lee H, Lee S, Lim, DS. cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes. EMBO J 2013; 32:1543–55; PMID:23644383; https://doi.org/10.1038/emboj.2013.102
   PubMedGoogle Scholar
• Suzuki H, Yabuta N, Okada N, Torigata K, Aylon Y, Oren M, Nojima H. Lats2 phosphorylates p21/CDKN1A after UV irradiation and regulates apoptosis. J Cell Sci 2013; 126:4358–68; PMID:23886938; https://doi.org/10.1242/jcs.125815
   PubMedGoogle Scholar
• Mashiko D, Fujihara Y, Satouh Y, Miyata H, Isotani A, Ikawa M. Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA. Sci Rep 2013; 3:3355; PMID:24284873; https://doi.org/10.1038/srep03355
   PubMed Web of Science ®Google Scholar