p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency

References

• Luger K. Dynamic nucleosomes. Chromosome Res 2006; 14:5-16; PMID: 16506092
   PubMed Web of Science ®Google Scholar
• Medina R, Ghule PN, Cruzat F, Barutcu AR, Montecino M, Stein JL, van Wijnen AJ, Stein GS. Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle. Mol Cell Biol 2012; 32:3860-71; PMID: 22826438; http://dx.doi.org/10.1128/MCB.00736-12
   PubMed Web of Science ®Google Scholar
• Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, et al. Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Mol Cancer 2012; 11:1; PMID: 22216762; http://dx.doi.org/10.1186/1476-4598-11-1
   PubMed Web of Science ®Google Scholar
• Stein GS, van Wijnen AJ, Stein JL, Lian JB, Montecino M, Zaidi SK, Braastad C. An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition. J Cell Physiol 2006; 209:706-10; PMID: 17001681
   PubMed Web of Science ®Google Scholar
• Braastad CD, Hovhannisyan H, van Wijnen AJ, Stein JL, Stein GS. Functional characterization of a human histone gene cluster duplication. Gene 2004; 342:35-40; PMID: 15527963
   PubMed Web of Science ®Google Scholar
• Holmes WF, Braastad CD, Mitra P, Hampe C, Doenecke D, Albig W, Stein JL, van Wijnen AJ, Stein GS. Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells. J Biol Chem 2005; 280:37400-7; PMID: 16131487
   PubMed Web of Science ®Google Scholar
• Medina R, Buck T, Zaidi SK, Miele-Chamberland A, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif. Biochemistry 2008; 47:11415-23; PMID: 18850719; http://dx.doi.org/10.1021/bi800961d
   PubMed Web of Science ®Google Scholar
• Mitra P, Xie RL, Medina R, Hovhannisyan H, Zaidi SK, Wei Y, Harper JW, Stein JL, van Wijnen AJ, Stein GS. Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase. Mol Cell Biol 2003; 23:8110-23; PMID: 14585971
   PubMed Web of Science ®Google Scholar
• Miele A, Braastad CD, Holmes WF, Mitra P, Medina R, Xie R, Zaidi SK, Ye X, Wei Y, Harper JW, et al. HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Mol Cell Biol 2005; 25:6140-53; PMID: 15988025
   PubMed Web of Science ®Google Scholar
• Medina R, van Wijnen AJ, Stein GS, Stein JL. The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT. Biochemistry 2006; 45:15915-20; PMID: 17176114
   PubMed Web of Science ®Google Scholar
• Zhao J, Dynlacht B, Imai T, Hori T, Harlow E. Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry. Genes Dev 1998; 12:456-61; PMID: 9472014
   PubMed Web of Science ®Google Scholar
• Zhao J, Kennedy BK, Lawrence BD, Barbie DA, Matera AG, Fletcher JA, Harlow E. NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription. Genes Dev 2000; 14:2283-97; PMID: 10995386
   PubMed Web of Science ®Google Scholar
• Ma T, Van Tine BA, Wei Y, Garrett MD, Nelson D, Adams PD, Wang J, Qin J, Chow LT, Harper JW. Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev 2000; 14:2298-313; PMID: 10995387
   PubMed Web of Science ®Google Scholar
• Ye X, Wei Y, Nalepa G, Harper JW. The cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cells. Mol Cell Biol 2003; 23:8586-600; PMID: 14612403
   PubMed Web of Science ®Google Scholar
• Ghule PN, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells. J Cell Physiol 2007; 213:9-17; PMID: 17520687
   PubMed Web of Science ®Google Scholar
• Ghule PN, Dominski Z, Yang XC, Marzluff WF, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells. Proc Natl Acad Sci U S A 2008; 105:16964-9; PMID: 18957539; http://dx.doi.org/10.1073/pnas.0809273105
   PubMed Web of Science ®Google Scholar
• Bongiorno-Borbone L, De Cola A, Vernole P, Finos L, Barcaroli D, Knight RA, Melino G, De Laurenzi V. FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy. Cell Cycle 2008; 7:2357-67; PMID: 18677100
   PubMed Web of Science ®Google Scholar
• Dominski Z, Marzluff WF. Formation of the 3′ end of histone mRNA: getting closer to the end. Gene 2007; 396:373-90; PMID: 17531405
   PubMed Web of Science ®Google Scholar
• Becker KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells. J Cell Physiol 2007; 210:517-26; PMID: 17096384
   PubMed Web of Science ®Google Scholar
• Gao G, Bracken AP, Burkard K, Pasini D, Classon M, Attwooll C, Sagara M, Imai T, Helin K, Zhao J. NPAT expression is regulated by E2F and is essential for cell cycle progression. Mol Cell Biol 2003; 23:2821-33; PMID: 12665581
   PubMed Web of Science ®Google Scholar
• Xie RL, Liu L, Mitra P, Stein JL, van Wijnen AJ, Stein GS. Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition. Gene 2007; 402:94-102; PMID: 17826007
   PubMed Web of Science ®Google Scholar
• Xie R, Medina R, Zhang Y, Hussain S, Colby J, Ghule P, Sundararajan S, Keeler M, Liu LJ, van der Deen M, et al. The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles. Proc Natl Acad Sci U S A 2009; 106:12359-64; PMID: 19590016; http://dx.doi.org/10.1073/pnas.0905651106
   PubMed Web of Science ®Google Scholar
• Liu LJ, Xie R, Hussain S, Lian JB, Rivera-Perez J, Jones SN, Stein JL, Stein GS, van Wijnen AJ. Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. Gene 2011; 483:1-10; PMID: 21605641; http://dx.doi.org/10.1016/j.gene.2011.05.002
   PubMed Web of Science ®Google Scholar
• Ghule PN, Xie RL, Medina R, Colby JL, Jones SN, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Fidelity of histone gene regulation is obligatory for genome replication and stability. Mol Cell Biol 2014; 34:2650-9; PMID: 24797072
   PubMed Web of Science ®Google Scholar
• Schwartz D, Rotter V. p53-dependent cell cycle control: response to genotoxic stress. Semin Cancer Biol 1998; 8:325-36; PMID: 10101798
   PubMed Web of Science ®Google Scholar
• Hanel W, Moll UM. Links between mutant p53 and genomic instability. J Cell Biochem 2012; 113:433-9; PMID: 22006292; http://dx.doi.org/10.1002/jcb.23400
   PubMed Web of Science ®Google Scholar
• Attardi LD, de Vries A, Jacks T. Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer. Oncogene 2004; 23:973-80; PMID: 14749764
   PubMed Web of Science ®Google Scholar
• Kastan MB, Zhan Q, el-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, Fornace AJ, Jr. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 1992; 71:587-97; PMID: 1423616
   PubMed Web of Science ®Google Scholar
• Harvey M, Sands AT, Weiss RS, Hegi ME, Wiseman RW, Pantazis P, Giovanella BC, Tainsky MA, Bradley A, Donehower LA. In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice. Oncogene 1993; 8:2457-67; PMID: 8103211
   PubMed Web of Science ®Google Scholar
• Jones SN, Sands AT, Hancock AR, Vogel H, Donehower LA, Linke SP, Wahl GM, Bradley A. The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2. Proc Natl Acad Sci U S A 1996; 93:14106-11; PMID: 8943068
   PubMed Web of Science ®Google Scholar
• Cross SM, Sanchez CA, Morgan CA, Schimke MK, Ramel S, Idzerda RL, Raskind WH, Reid BJ. A p53-dependent mouse spindle checkpoint. Science 1995; 267:1353-6; PMID: 7871434
   PubMed Web of Science ®Google Scholar
• Fukasawa K, Choi T, Kuriyama R, Rulong S, Vande Woude GF. Abnormal centrosome amplification in the absence of p53. Science 1996; 271:1744-7; PMID: 8596939
   PubMed Web of Science ®Google Scholar
• Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, et al. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat Cell Biol 2002; 4:993-7; PMID: 12447390
   PubMed Web of Science ®Google Scholar
• Anderson L, Henderson C, Adachi Y. Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage. Mol Cell Biol 2001; 21:1719-29; PMID: 11238909
   PubMed Web of Science ®Google Scholar
• Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358:15-6; PMID: 1614522
   PubMed Web of Science ®Google Scholar
• Agarwal ML, Agarwal A, Taylor WR, Stark GR. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci U S A 1995; 92:8493-7; PMID: 7667317
   PubMed Web of Science ®Google Scholar
• Houtgraaf JH, Versmissen J, van der Giessen WJ. A concise review of DNA damage checkpoints and repair in mammalian cells. Cardiovasc Revasc Med 2006; 7:165-72; PMID: 16945824
   PubMedGoogle Scholar
• Khoo KH, Verma CS, Lane DP. Drugging the p53 pathway: understanding the route to clinical efficacy. Nat Rev Drug Discov 2014; 13:217-36; PMID: 24577402; http://dx.doi.org/10.1038/nrd4236
   PubMed Web of Science ®Google Scholar
• Cheok CF, Verma CS, Baselga J, Lane DP. Translating p53 into the clinic. Nat Rev Clin Oncol 2011; 8:25-37; PMID: 20975744; http://dx.doi.org/10.1038/nrclinonc.2010.174
   PubMed Web of Science ®Google Scholar
• Riley T, Sontag E, Chen P, Levine A. Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 2008; 9:402-12; PMID: 18431400; http://dx.doi.org/10.1038/nrm2395
   PubMed Web of Science ®Google Scholar
• Vazquez A, Bond EE, Levine AJ, Bond GL. The genetics of the p53 pathway, apoptosis and cancer therapy. Nat Rev Drug Discov 2008; 7:979-87; PMID: 19043449; http://dx.doi.org/10.1038/nrd2656
   PubMed Web of Science ®Google Scholar
• Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr., Butel JS, Bradley A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 1992; 356:215-21; PMID: 1552940
   PubMed Web of Science ®Google Scholar