Metabolic epistasis among apoptosis-inducing factor and the mitochondrial import factor CHCHD4

References

• Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397:441-6; PMID:9989411; http://dx.doi.org/10.1038/17135
   PubMed Web of Science ®Google Scholar
• Patterson SD, Spahr CS, Daugas E, Susin SA, Irinopoulou T, Koehler C, Kroemer G. Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition. Cell Death Differ 2000; 7:137-44; PMID:10713728; http://dx.doi.org/10.1038/sj.cdd.4400640
   PubMed Web of Science ®Google Scholar
• Norberg E, Karlsson M, Korenovska O, Szydlowski S, Silberberg G, Uhlen P, Orrenius S, Zhivotovsky B. Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis. EMBO J 2010; 29:3869-78; PMID:21037554; http://dx.doi.org/10.1038/emboj.2010.253
   PubMed Web of Science ®Google Scholar
• Ye H, Cande C, Stephanou NC, Jiang S, Gurbuxani S, Larochette N, Daugas E, Garrido C, Kroemer G, Wu H. DNA binding is required for the apoptogenic action of apoptosis inducing factor. Nat Struct Biol 2002; 9:680-4; PMID:12198487; http://dx.doi.org/10.1038/nsb836
   PubMedGoogle Scholar
• Mate MJ, Ortiz-Lombardia M, Boitel B, Haouz A, Tello D, Susin SA, Penninger J, Kroemer G, Alzari PM. The crystal structure of the mouse apoptosis-inducing factor AIF. Nat Struct Biol 2002; 9:442-6; PMID:11967568; http://dx.doi.org/10.1038/nsb793
   PubMedGoogle Scholar
• Zhu C, Wang X, Deinum J, Huang Z, Gao J, Modjtahedi N, Neagu MR, Nilsson M, Eriksson PS, Hagberg H, et al. Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia. J Exp Med 2007; 204:1741-8; PMID:17635954; http://dx.doi.org/10.1084/jem.20070193
   PubMed Web of Science ®Google Scholar
• Cande C, Vahsen N, Kouranti I, Schmitt E, Daugas E, Spahr C, Luban J, Kroemer RT, Giordanetto F, Garrido C, et al. AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogene 2004; 23:1514-21; PMID:14716299; http://dx.doi.org/10.1038/sj.onc.1207279
   PubMed Web of Science ®Google Scholar
• Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CY, Sasaki T, Elia AJ, Cheng HY, Ravagnan L, et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001; 410:549-54; PMID:11279485; http://dx.doi.org/10.1038/35069004
   PubMed Web of Science ®Google Scholar
• Joza N, Galindo K, Pospisilik JA, Benit P, Rangachari M, Kanitz EE, Nakashima Y, Neely GG, Rustin P, Abrams JM, et al. The molecular archaeology of a mitochondrial death effector: AIF in Drosophila. Cell Death Differ 2008; 15:1009-18; PMID:18309327; http://dx.doi.org/10.1038/cdd.2008.24
   PubMed Web of Science ®Google Scholar
• Hisatomi T, Sakamoto T, Murata T, Yamanaka I, Oshima Y, Hata Y, Ishibashi T, Inomata H, Susin SA, Kroemer G. Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo. Am J Pathol 2001; 158:1271-8; PMID:11290545; http://dx.doi.org/10.1016/S0002-9440(10)64078-3
   PubMed Web of Science ®Google Scholar
• Penninger JM, Kroemer G. Mitochondria, AIF and caspases–rivaling for cell death execution. Nat Cell Biol 2003; 5:97-9; PMID:12563272; http://dx.doi.org/10.1038/ncb0203-97
   PubMed Web of Science ®Google Scholar
• Cande C, Vahsen N, Garrido C, Kroemer G. Apoptosis-inducing factor (AIF): caspase-independent after all. Cell Death Differ 2004; 11:591-5; PMID:15017385
   PubMed Web of Science ®Google Scholar
• Zhu C, Wang X, Huang Z, Qiu L, Xu F, Vahsen N, Nilsson M, Eriksson PS, Hagberg H, Culmsee C, et al. Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. Cell Death Differ 2007; 14:775-84; PMID:17039248; http://dx.doi.org/10.1038/sj.cdd.4402053
   PubMed Web of Science ®Google Scholar
• Osato KY, Sato Y, Ochiishi T, Osato A, C Zhu C, Sato M, Swanpalmer J, Modjtahedi N, Kroemer G, Kuhn HG, et al. Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation. Cell Death and Disease 2010; 1:e84; PMID:21368857; http://dx.doi.org/10.1038/cddis.2010.63
   PubMed Web of Science ®Google Scholar
• Hangen E, Blomgren K, Benit P, Kroemer G, Modjtahedi N. Life with or without AIF. Trends Biochem Sci 2010; 35:278-87; PMID:20138767; http://dx.doi.org/10.1016/j.tibs.2009.12.008
   PubMed Web of Science ®Google Scholar
• Vahsen N, Cande C, Briere JJ, Benit P, Joza N, Larochette N, Mastroberardino PG, Pequignot MO, Casares N, Lazar V, et al. AIF deficiency compromises oxidative phosphorylation. EMBO J 2004; 23:4679-89; PMID:15526035; http://dx.doi.org/10.1038/sj.emboj.7600461
   PubMed Web of Science ®Google Scholar
• Wissing S, Ludovico P, Herker E, Buttner S, Engelhardt SM, Decker T, Link A, Proksch A, Rodrigues F, Corte-Real M, et al. An AIF orthologue regulates apoptosis in yeast. J Cell Biol 2004; 166:969-74; PMID:15381687; http://dx.doi.org/10.1083/jcb.200404138
   PubMed Web of Science ®Google Scholar
• Joza N, Oudit GY, Brown D, Benit P, Kassiri Z, Vahsen N, Benoit L, Patel MM, Nowikovsky K, Vassault A, et al. Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy. Mol Cell Biol 2005; 25:10261-72; PMID:16287843; http://dx.doi.org/10.1128/MCB.25.23.10261-10272.2005
   PubMed Web of Science ®Google Scholar
• Ghezzi D, Sevrioukova IF, Invernizzi F, Lamperti C, Mora M, D'Adamo P, Novara F, Zuffardi O, Uziel G, Zeviani M. Severe X-linked mitochondrial encephalomyopathy associated with a mutation in Apoptosis-Inducing factor. The American journal of human Genetics 2010; 86:639-49; http://dx.doi.org/10.1016/j.ajhg.2010.03.002
   PubMed Web of Science ®Google Scholar
• Modjtahedi N, Giordanetto F, Kroemer G. A human mitochondriopathy caused by AIF mutation. Cell Death Differ 2010; 17:1525-8; PMID:20835254; http://dx.doi.org/10.1038/cdd.2010.88
   PubMed Web of Science ®Google Scholar
• Rinaldi C, Grunseich C, Sevrioukova IF, Schindler A, Horkayne-Szakaly I, Lamperti C, Landouré G, Kennerson ML, Burnett BG, Bönnemann C, et al. Cowchock syndrome is associated with a mutation in apoptosis-inducing factor. Am J Hum Genet 2012; 91:1095-102; PMID:23217327; http://dx.doi.org/10.1016/j.ajhg.2012.10.008
   PubMed Web of Science ®Google Scholar
• Berger I, Ben-Neriah Z, Dor-Wolman T, Shaag A, Saada A, Zenvirt S, Raas-Rothschild A, Nadjari M, Kaestner KH, Elpeleg O. Early prenatal ventriculomegaly due to an AIFM1 mutation identified by linkage analysis and whole exome sequencing. Mol Genet Metab 2011; 104:517-20; PMID:22019070; http://dx.doi.org/10.1016/j.ymgme.2011.09.020
   PubMed Web of Science ®Google Scholar
• Zong L, Guan J, Ealy M, Zhang Q, Wang D, Wang H, Zhao Y, Shen Z, Campbell CA, Wang F, et al. Mutations in apoptosis-inducing factor cause X-linked recessive auditory neuropathy spectrum disorder. J Med Genet 2015; PMID:25986071
   PubMed Web of Science ®Google Scholar
• Hangen E, Féraud O, Lachkar S, Mou H, Doti N, Fimia GM, Lam NV, Zhu C, Godin I, Muller K, et al. Interaction between AIF and CHCHD4 regulates respiratory chain biogenesis. Mol Cell 2015; 58:1001-14; PMID:26004228; http://dx.doi.org/10.1016/j.molcel.2015.04.020
   PubMed Web of Science ®Google Scholar
• Hofmann S, Rothbauer U, Muhlenbein N, Baiker K, Hell K, Bauer MF. Functional and mutational characterization of human MIA40 acting during import into the mitochondrial intermembrane space. J Mol Biol 2005; 353:517-28; PMID:16185709; http://dx.doi.org/10.1016/j.jmb.2005.08.064
   PubMed Web of Science ®Google Scholar
• Chacinska A, Guiard B, Muller JM, Schulze-Specking A, Gabriel K, Kutik S, Pfanner N. Mitochondrial biogenesis, switching the sorting pathway of the intermembrane space receptor Mia40. J Biol Chem 2008; 283:29723-9; PMID:18779329; http://dx.doi.org/10.1074/jbc.M805356200
   PubMed Web of Science ®Google Scholar
• Klein JA, Longo-Guess CM, Rossmann MP, Seburn KL, Hurd RE, Frankel WN, Bronson RT, Ackerman SL. The harlequin mouse mutation downregulates apoptosis-inducing factor. Nature 2002; 419:367-74; PMID:12353028; http://dx.doi.org/10.1038/nature01034
   PubMed Web of Science ®Google Scholar
• Pospisilik JA, Knauf C, Joza N, Benit P, Orthofer M, Cani PD, Ebersberger I, Nakashima T, Sarao R, Neely G, et al. Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell 2007; 131:476-91; PMID:17981116; http://dx.doi.org/10.1016/j.cell.2007.08.047
   PubMed Web of Science ®Google Scholar
• Nargund AM, Pellegrino MW, Fiorese CJ, Baker BM, Haynes CM. Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation. Science 2012; 337:587-90; PMID:22700657; http://dx.doi.org/10.1126/science.1223560
   PubMed Web of Science ®Google Scholar
• Mouchiroud L, Houtkooper RH, Moullan N, Katsyuba E, Ryu D, Canto C, Mottis A, Jo YS, Viswanathan M, Schoonjans K, et al. The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling. Cell 2013; 154:430-41; PMID:23870130; http://dx.doi.org/10.1016/j.cell.2013.06.016
   PubMed Web of Science ®Google Scholar
• Zhuang J, Wang PY, Huang X, Chen X, Kang JG, Hwang PM. Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity. Proc Natl Acad Sci U S A 2013; 110:17356-61; PMID:24101517; http://dx.doi.org/10.1073/pnas.1310908110
   PubMed Web of Science ®Google Scholar
• Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, et al. p53 Activation in adipocytes of obese mice. J Biol Chem 2003; 278:25395-400; PMID:12734185; http://dx.doi.org/10.1074/jbc.M302364200
   PubMed Web of Science ®Google Scholar
• Molchadsky A, Ezra O, Amendola PG, Krantz D, Kogan-Sakin I, Buganim Y, Rivlin N, Goldfinger N, Folgiero V, Falcioni R, et al. p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity. Cell Death Differ 2013; 20:774-83; PMID:23412343; http://dx.doi.org/10.1038/cdd.2013.9
   PubMed Web of Science ®Google Scholar