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CHFR is important for the survival of male premeiotic germ cells

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Pages 3454-3460 | Received 29 Apr 2015, Accepted 07 Sep 2015, Published online: 13 Nov 2015

References

  • Wosnitzer M, Goldstein M, Hardy MP. Review of Azoospermia. Spermatogenesis 2014; 4:e28218; PMID:25105055; http://dx.doi.org/10.4161/spmg.28218
  • Lu LY, Yu X. Double-strand break repair on sex chromosomes: challenges during male meiotic prophase. Cell Cycle 2015; 14:516-525; PMID:25565522
  • Romanienko PJ, Camerini-Otero RD. The mouse Spo11 gene is required for meiotic chromosome synapsis. Mol Cell 2000; 6:975-987; PMID:11106738; http://dx.doi.org/10.1016/S1097-2765(00)00097-6
  • Baudat F, Manova K, Yuen JP, Jasin M, Keeney S. Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11. Mol Cell 2000; 6:989-998; PMID:11106739; http://dx.doi.org/10.1016/S1097-2765(00)00098-8
  • Lu LY, Xiong Y, Kuang H, Korakavi G, Yu X. Regulation of the DNA damage response on male meiotic sex chromosomes. Nat Commun 2013; 4:2105; PMID:23812044
  • Fernandez-Capetillo O, Mahadevaiah SK, Celeste A, Romanienko PJ, Camerini-Otero RD, Bonner WM, Manova K, Burgoyne P, Nussenzweig A. H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. Dev Cell 2003; 4:497-508; PMID:12689589; http://dx.doi.org/10.1016/S1534-5807(03)00093-5
  • Lou Z, Minter-Dykhouse K, Franco S, Gostissa M, Rivera MA, Celeste A, Manis JP, van Deursen J, Nussenzweig A, Paull TT. MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol Cell 2006; 21:187-200; PMID:16427009; http://dx.doi.org/10.1016/j.molcel.2005.11.025
  • Xu Y, Ashley T, Brainerd EE, Bronson RT, Meyn MS, Baltimore D. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Gen Dev 1996; 10:2411-2422; PMID:8843194; http://dx.doi.org/10.1101/gad.10.19.2411
  • Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F, Shiloh Y, Crawley JN, Ried T, Tagle D, et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 1996; 86:159-171; PMID:8689683; http://dx.doi.org/10.1016/S0092-8674(00)80086-0
  • Marcon L, Boissonneault G. Transient DNA strand breaks during mouse and human spermiogenesis new insights in stage specificity and link to chromatin remodeling. Biol Reprod 2004; 70:910-918; PMID:14645105; http://dx.doi.org/10.1095/biolreprod.103.022541
  • Lu LY, Wu J, Ye L, Gavrilina GB, Saunders TL, Yu X. RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis. Dev Cell 2010; 18:371-384; PMID:20153262; http://dx.doi.org/10.1016/j.devcel.2010.01.010
  • Roest HP, van Klaveren J, de Wit J, van Gurp CG, Koken MH, Vermey M, van Roijen JH, Hoogerbrugge JW, Vreeburg JT, Baarends WM, et al. Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. Cell 1996; 86:799-810; PMID:8797826; http://dx.doi.org/10.1016/S0092-8674(00)80154-3
  • Kanatsu-Shinohara M, Shinohara T. Spermatogonial stem cell self-renewal and development. Ann Rev Cell Dev Biol 2013; 29:163-187; PMID:24099084; http://dx.doi.org/10.1146/annurev-cellbio-101512-122353
  • Takubo K, Hirao A, Ohmura M, Azuma M, Arai F, Nagamatsu G, Suda T. Premeiotic germ cell defect in seminiferous tubules of Atm-null testis. Biochem Biophys Res Commun 2006; 351:993-998; PMID:17097049; http://dx.doi.org/10.1016/j.bbrc.2006.10.145
  • Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada W, Arai F, Hirao A, Suda T. Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest. Cell stem cell 2008; 2:170-182; PMID:18371438; http://dx.doi.org/10.1016/j.stem.2007.10.023
  • Sun J, Yomogida K, Sakao S, Yamamoto H, Yoshida K, Watanabe K, Morita T, Araki K, Yamamura K, Tateishi S. Rad18 is required for long-term maintenance of spermatogenesis in mouse testes. Mech Dev 2009; 126:173-183; PMID:19068231; http://dx.doi.org/10.1016/j.mod.2008.11.004
  • Bohgaki T, Bohgaki M, Cardoso R, Panier S, Zeegers D, Li L, Stewart GS, Sanchez O, Hande MP, Durocher D, et al. Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome. PLoS Genet 2011; 7:e1001381; PMID:21552324; http://dx.doi.org/10.1371/journal.pgen.1001381
  • Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X. Chfr and RNF8 synergistically regulate ATM activation. Nat Struct Mol Biol 2011; 18:761-768; PMID:21706008; http://dx.doi.org/10.1038/nsmb.2078
  • Liu C, Wu J, Paudyal SC, You Z, Yu X. CHFR is important for the first wave of ubiquitination at DNA damage sites. Nucleic Acids Res 2013; 41:1698-1710; PMID:23268447; http://dx.doi.org/10.1093/nar/gks1278
  • Yu X, Minter-Dykhouse K, Malureanu L, Zhao WM, Zhang D, Merkle CJ, Ward IM, Saya H, Fang G, van Deursen J, et al. Chfr is required for tumor suppression and Aurora A regulation. Nat Genet 2005; 37:401-406; PMID:15793587; http://dx.doi.org/10.1038/ng1538
  • Rube CE, Zhang S, Miebach N, Fricke A, Rube C. Protecting the heritable genome: DNA damage response mechanisms in spermatogonial stem cells. DNA Repair 2011; 10:159-168; PMID:21123119; http://dx.doi.org/10.1016/j.dnarep.2010.10.007
  • Barlow C, Liyanage M, Moens PB, Tarsounas M, Nagashima K, Brown K, Rottinghaus S, Jackson SP, Tagle D, Ried T, et al. Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I. Development 1998; 125:4007-4017; PMID:9735362
  • Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, et al. RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. J Cell Biol 2007; 176:581-592; PMID:17312021; http://dx.doi.org/10.1083/jcb.200608130

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