Bursicon-α subunit modulates dLGR2 activity in the adult Drosophila melanogaster midgut independently to Bursicon-β

References

• An S, Dong S, Wang Q, Li S, Gilbert LI, Stanley D, Song Q. Insect neuropeptide bursicon homodimers induce innate immune and stress genes during molting by activating the NF-kappaB transcription factor Relish. PLoS One 2012; 7(3):e34510; PMID:22470576; http://dx.doi.org/10.1371/journal.pone.0034510
   PubMedGoogle Scholar
• Arakane Y, Li B, Muthukrishnan S, Beeman RW, Kramer KJ, Park Y. Functional analysis of four neuropeptides, EH, ETH, CCAP and bursicon, and their receptors in adult ecdysis behavior of the red flour beetle, Tribolium castaneum. Mech Dev 2008; 125(11–12): 984-95; PMID:18835439; http://dx.doi.org/10.1016/j.mod.2008.09.002
   PubMed Web of Science ®Google Scholar
• Buchon N, Osman D, David FP, Fang HY, Boquete JP, Deplancke B, Lemaitre B. Morphological and molecular characterization of adult midgut compartmentalization in Drosophila. Cell Rep 2013; 3(5):1725-38; PMID:23643535; http://dx.doi.org/10.1016/j.celrep.2013.04.001
   PubMed Web of Science ®Google Scholar
• Chintapalli VR, Wang J, Dow JA. Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nat Genet 2007; 39(6):715-20; PMID:17534367; http://dx.doi.org/10.1038/ng2049
   PubMed Web of Science ®Google Scholar
• Dai L, Dewey EM, Zitnan D, Luo CW, Honegger HW, Adams ME. Identification, developmental expression, and functions of bursicon in the tobacco hawkmoth, Manduca sexta. J Comp Neurol 2008; 506(5):759-74;PMID:18076057; http://dx.doi.org/10.1002/cne.21575
   PubMed Web of Science ®Google Scholar
• Dewey EM, McNabb SL, Ewer J, Kuo GR, Takanishi CL, Truman JW, Honegger HW. Identification of the gene encoding bursicon, an insect neuropeptide responsible for cuticle sclerotization and wing spreading. Curr Biol 2004; 14(13):1208-13; PMID:15242619; http://dx.doi.org/10.1016/j.cub.2004.06.051
   PubMed Web of Science ®Google Scholar
• Dutta D, Dobson AJ, Houtz PL, Glasser C, Revah J, Korzelius J, Patel PH, Edgar BA, Buchon N. Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut. Cell Rep 2015; 12(2):346-58; PMID:26146076; http://dx.doi.org/10.1016/j.celrep.2015.06.009
   PubMed Web of Science ®Google Scholar
• Honegger HW, Dewey EM, Ewer J. Bursicon, the tanning hormone of insects: recent advances following the discovery of its molecular identity. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2008; 194(12): 989-1005; PMID:19005656; http://dx.doi.org/10.1007/s00359-008-0386-3
   PubMed Web of Science ®Google Scholar
• Honegger HW, Estevez-Lao TY, Hillyer JF. Bursicon-expressing neurons undergo apoptosis after adult ecdysis in the mosquito Anopheles gambiae. J Insect Physiol 2011; 57(7):1017-22; PMID:21554887; http://dx.doi.org/10.1016/j.jinsphys.2011.04.019
   PubMed Web of Science ®Google Scholar
• Honegger HW, Market D, Pierce LA, Dewey EM, Kostron B, Wilson M, Choi D, Klukas KA, Mesce KA. Cellular localization of bursicon using antisera against partial peptide sequences of this insect cuticle-sclerotizing neurohormone. J Comp Neurol 2002; 452(2):163-77; PMID:12271490; http://dx.doi.org/10.1002/cne.10357
   PubMed Web of Science ®Google Scholar
• Jiang H, Patel PH, Kohlmaier A, Grenley MO, McEwen DG, Edgar, BA. Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell 2009; 137(7):1343-55; PMID:19563763; http://dx.doi.org/10.1016/j.cell.2009.05.014
   PubMed Web of Science ®Google Scholar
• Lahr EC, Dean D, Ewer J. Genetic analysis of ecdysis behavior in Drosophila reveals partially overlapping functions of two unrelated neuropeptides. J Neurosci 2012; 32(20):6819-29; PMID:22593051; http://dx.doi.org/10.1523/JNEUROSCI.5301-11.2012
   PubMed Web of Science ®Google Scholar
• Luo CW, Dewey EM, Sudo S, Ewer J, Hsu SY, Honegger HW, Hsueh AJ. Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proc Natl Acad Sci USA 2005; 102(8):2820-5; PMID:15703293; http://dx.doi.org/10.1073/pnas.0409916102
   PubMed Web of Science ®Google Scholar
• Mendive FM, Van Loy T, Claeysen S, Poels J, Williamson M, Hauser F, Grimmelikhuijzen CJ, Vassart G, Vanden Broeck J. Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2. FEBS Lett 2005; 579(10):2171-6; PMID:15811337; http://dx.doi.org/10.1016/j.febslet.2005.03.006
   PubMed Web of Science ®Google Scholar
• Peabody NC, Diao F, Luan H, Wang H, Dewey EM, Honegger HW, White BH. Bursicon functions within the Drosophila CNS to modulate wing expansion behavior, hormone secretion, and cell death. J Neurosci 2008; 28(53):14379-91; PMID:19118171; http://dx.doi.org/10.1523/JNEUROSCI.2842-08.2008
   PubMed Web of Science ®Google Scholar
• Ponsioen B, Zhao J, Riedl J, Zwartkruis F, van der Krogt G, Zaccolo M, Moolenaar WH, Bos JL, Jalink K. Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator. EMBO Rep 2004; 5(12):1176-80; PMID:15550931.
   PubMed Web of Science ®Google Scholar
• Scopelliti A, Cordero JB, Diao F, Strathdee K, White BH, Sansom OJ, Vidal M. Local control of intestinal stem cell homeostasis by enteroendocrine cells in the adult Drosophila midgut. Curr Biol 2014; 24(11):1199-211; PMID:24814146; http://dx.doi.org/10.1016/j.cub.2014.04.007
   PubMed Web of Science ®Google Scholar
• Truman JW. Hormonal control of insect ecdysis: endocrine cascades for coordinating behavior with physiology. Vitam Horm 2005; 73:1-30; PMID:16399406; http://dx.doi.org/10.1016/S0083-6729(05)73001-6
   PubMed Web of Science ®Google Scholar