1,877
Views
18
CrossRef citations to date
0
Altmetric
Report

Spatial regulation of greatwall by Cdk1 and PP2A-Tws in the cell cycle

, , , , , & show all
Pages 528-539 | Received 27 Jul 2015, Accepted 27 Nov 2015, Published online: 09 Mar 2016

References

  • Castilho PV, Williams BC, Mochida S, Zhao Y, Goldberg ML. The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites. Mol Biol Cell 2009; 20:4777-89; PMID:19793917; http://dx.doi.org/10.1091/mbc.E09-07-0643
  • Mayer-Jaekel RE, Ohkura H, Ferrigno P, Andjelkovic N, Shiomi K, Uemura T, Glover DM, Hemmings BA. Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2. J Cell Sci 1994; 107 ( Pt 9):2609-16; PMID:7844174
  • Mochida S, Ikeo S, Gannon J, Hunt T. Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts. Embo J 2009; 28:2777-85; PMID:19696736; http://dx.doi.org/10.1038/emboj.2009.238
  • Mochida S, Maslen SL, Skehel M, Hunt T. Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis. Science 2010; 330:1670-3; PMID:21164013; http://dx.doi.org/10.1126/science.1195689
  • Gharbi-Ayachi A, Labbe JC, Burgess A, Vigneron S, Strub JM, Brioudes E, Van-Dorsselaer A, Castro A, Lorca T. The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A. Science 2010; 330:1673-7; PMID:21164014; http://dx.doi.org/10.1126/science.1197048
  • Rangone H, Wegel E, Gatt MK, Yeung E, Flowers A, Debski J, Dadlez M, Janssens V, Carpenter AT, Glover DM. Suppression of scant identifies Endos as a substrate of greatwall kinase and a negative regulator of protein phosphatase 2A in mitosis. PLoS Genet 2011; 7:e1002225; PMID:21852956; http://dx.doi.org/10.1371/journal.pgen.1002225
  • Williams BC, Filter JJ, Blake-Hodek KA, Wadzinski BE, Fuda NJ, Shalloway D, Goldberg ML. Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers. Elife 2014; 3:e01695; PMID:24618897
  • Mochida S. Regulation of α-endosulfine, an inhibitor of protein phosphatase 2A, by multisite phosphorylation. FEBS J 2014; 281:1159-69; PMID:24354984; http://dx.doi.org/10.1111/febs.12685
  • Yu J, Zhao Y, Li Z, Galas S, Goldberg ML. Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts. Mol Cell 2006; 22:83-91; PMID:16600872; http://dx.doi.org/10.1016/j.molcel.2006.02.022
  • Yu J, Fleming SL, Williams B, Williams EV, Li Z, Somma P, Rieder CL, Goldberg ML. Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila. J Cell Biol 2004; 164:487-92; PMID:14970188; http://dx.doi.org/10.1083/jcb.200310059
  • Archambault V, Zhao X, White-Cooper H, Carpenter AT, Glover DM. Mutations in Drosophila Greatwall/Scant Reveal Its Roles in Mitosis and Meiosis and Interdependence with Polo Kinase. PLoS Genet 2007; 3:e200; PMID:17997611; http://dx.doi.org/10.1371/journal.pgen.0030200
  • Burgess A, Vigneron S, Brioudes E, Labbe JC, Lorca T, Castro A. Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance. Proc Natl Acad Sci U S A 2010; 107:12564-9; PMID:20538976; http://dx.doi.org/10.1073/pnas.0914191107
  • Voets E, Wolthuis RM. MASTL is the human orthologue of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis. Cell Cycle 2010; 9:3591-601; PMID:20818157; http://dx.doi.org/10.4161/cc.9.17.12832
  • Alvarez-Fernandez M, Sanchez-Martinez R, Sanz-Castillo B, Gan PP, Sanz-Flores M, Trakala M, Ruiz-Torres M, Lorca T, Castro A, Malumbres M. Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals. Proc Natl Acad Sci U S A 2013; 110:17374-9; PMID:24101512; http://dx.doi.org/10.1073/pnas.1310745110
  • Kim MY, Bucciarelli E, Morton DG, Williams BC, Blake-Hodek K, Pellacani C, Von Stetina JR, Hu X, Somma MP, Drummond-Barbosa D, et al. Bypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans. Genetics 2012; 191:1181-97; PMID:22649080; http://dx.doi.org/10.1534/genetics.112.140574
  • Li YH, Kang H, Xu YN, Heo YT, Cui XS, Kim NH, Oh JS. Greatwall Kinase Is Required for Meiotic Maturation in Porcine Oocytes. Biol Reprod 2013; 89(3):53.
  • Adhikari D, Diril MK, Busayavalasa K, Risal S, Nakagawa S, Lindkvist R, Shen Y, Coppola V, Tessarollo L, Kudo NR, et al. Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II. J Cell Biol 2014; 206:843-53; PMID:25246615; http://dx.doi.org/10.1083/jcb.201406033
  • Vigneron S, Gharbi-Ayachi A, Raymond AA, Burgess A, Labbe JC, Labesse G, Monsarrat B, Lorca T, Castro A. Characterization of the mechanisms controlling Greatwall activity. Mol Cell Biol 2011; 31:2262-75; PMID:21444715; http://dx.doi.org/10.1128/MCB.00753-10
  • Blake-Hodek KA, Williams BC, Zhao Y, Castilho PV, Chen W, Mao Y, Yamamoto TM, Goldberg ML. Determinants for Activation of the Atypical AGC Kinase Greatwall during M Phase Entry. Mol Cell Biol 2012; 32:1337-53; PMID:22354989; http://dx.doi.org/10.1128/MCB.06525-11
  • Yamamoto TM, Wang L, Fisher LA, Eckerdt FD, Peng A. Regulation of Greatwall kinase by protein stabilization and nuclear localization. Cell Cycle 2014; 13:3565-75; PMID:25483093; http://dx.doi.org/10.4161/15384101.2014.962942
  • Wang P, Galan JA, Normandin K, Bonneil E, Hickson GR, Roux PP, Thibault P, Archambault V. Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression. J Cell Biol 2013; 202:277-93; PMID:23857770; http://dx.doi.org/10.1083/jcb.201211141
  • Wang P, Malumbres M, Archambault V. The Greatwall-PP2A axis in cell cycle control. Methods Mol Biol 2014; 1170:99-111; PMID:24906311; http://dx.doi.org/10.1007/978-1-4939-0888-2_6
  • Santos SD, Wollman R, Meyer T, Ferrell JE, Jr. Spatial positive feedback at the onset of mitosis. Cell 2012; 149:1500-13; PMID:22726437; http://dx.doi.org/10.1016/j.cell.2012.05.028
  • Pedruzzi I, Dubouloz F, Cameroni E, Wanke V, Roosen J, Winderickx J, De Virgilio C. TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0. Mol Cell 2003; 12:1607-13; PMID:14690612; http://dx.doi.org/10.1016/S1097-2765(03)00485-4
  • Wanke V, Pedruzzi I, Cameroni E, Dubouloz F, De Virgilio C. Regulation of G0 entry by the Pho80-Pho85 cyclin-CDK complex. EMBO J 2005; 24:4271-8; PMID:16308562; http://dx.doi.org/10.1038/sj.emboj.7600889
  • Cundell MJ, Bastos RN, Zhang T, Holder J, Gruneberg U, Novak B, Barr FA. The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation. Mol Cell 2013; 52:393-405; PMID:24120663; http://dx.doi.org/10.1016/j.molcel.2013.09.005
  • Vigneron S, Brioudes E, Burgess A, Labbe JC, Lorca T, Castro A. Greatwall maintains mitosis through regulation of PP2A. Embo J 2009; 28:2786-93; PMID:19680222; http://dx.doi.org/10.1038/emboj.2009.228
  • Yamamoto TM, Blake-Hodek K, Williams BC, Lewellyn AL, Goldberg ML, Maller JL. Regulation of Greatwall kinase during Xenopus oocyte maturation. Mol Biol Cell 2011; 22:2157-64; PMID:21551066; http://dx.doi.org/10.1091/mbc.E11-01-0008
  • Hegarat N, Vesely C, Vinod PK, Ocasio C, Peter N, Gannon J, Oliver AW, Novák B, Hochegger H. PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit. PLoS Genet 2014; 10:e1004004; PMID:24391510; http://dx.doi.org/10.1371/journal.pgen.1004004
  • Chen F, Archambault V, Kar A, Lio P, D'Avino PP, Sinka R, Lilley K, Laue ED, Deak P, Capalbo L, et al. Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol 2007; 17:293-303; PMID:17306545; http://dx.doi.org/10.1016/j.cub.2007.01.068
  • Heim A, Konietzny A, Mayer TU. Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit. EMBO Rep 2015; 16:1501-10; PMID:26396231; http://dx.doi.org/10.15252/embr.201540876
  • Archambault V, D'Avino PP, Deery MJ, Lilley KS, Glover DM. Sequestration of Polo kinase to microtubules by phosphopriming-independent binding to Map205 is relieved by phosphorylation at a CDK site in mitosis. Genes Dev 2008; 22:2707-20; PMID:18832073; http://dx.doi.org/10.1101/gad.486808
  • Daul AL, Komori H, Lee CY. Immunofluorescent staining of Drosophila larval brain tissue. Cold Spring Harb Protoc 2010; 2010:pdb prot5460
  • Nissim-Rafinia M, Meshorer E. Photobleaching assays (FRAP & FLIP) to measure chromatin protein dynamics in living embryonic stem cells. J Vis Exp 2011; PMID:21730953
  • D'Avino PP, Archambault V, Przewloka MR, Zhang W, Laue ED, Glover DM. Isolation of protein complexes involved in mitosis and cytokinesis from Drosophila cultured cells. Methods Mol Biol 2009; 545:99-112; PMID:19475384; http://dx.doi.org/10.1007/978-1-60327-993-2_6
  • Fu SC, Huang HC, Horton P, Juan HF. ValidNESs: a database of validated leucine-rich nuclear export signals. Nucleic Acids Res 2013; 41:D338-43; PMID:23093589; http://dx.doi.org/10.1093/nar/gks936

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.