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Editorials: Cell Cycle Features

How RNA modification allows non-conventional decoding in mitochondria

, &
Pages 145-146 | Received 30 Aug 2016, Accepted 07 Sep 2016, Published online: 01 Nov 2016

References

  • Haag S, Sloan KE, Ranjan N, Warda AS, Kretschmer J, Blessing C, Hübner B, Seikowski J, Dennerlein S, Rehling P, et al. NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. EMBO J 2016; 35:2104–2119; PMID: 27497299; https://dx.doi.org/10.15252/embj.201694885
  • Nakano S, Suzuki T, Kawarada L, Iwata H, Asano K, Suzuki T. NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNAMet. Nat Chem Biol 2016; 12(7):546–51; PMID: 27214402; https://dx.doi.org/10.1038/nchembio.2099
  • Van Haute L, Dietmann S, Kremer L, Hussain S, Pearce SF, Powell CA, Rorbach J, Lantaff R, Blanco S, Sauer S, et al. Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3. Nat Commun 2016; 7:12039. PMID: 27356879; https://dx.doi.org/10.1038/ncomms12039
  • Brzezicha B, Schmidt M, Makalowska I, Jarmolowski A, Pienkowska J, Szweykowska-Kulinska Z. Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNA Leu (CAA). Nucleic Acids Res 2006; 34(20):6034–43. PMID:17071714; https://dx.doi.org/10.1093/nar/gkl765
  • Haag S, Warda AS, Kretschmer J, Günnigmann MA, Höbartner C, Bohnsack MT. NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs. RNA 2015; 21(9):1532–43; PMID: 26160102; https://dx.doi.org/10.1261/rna.051524.115
  • Bilbille Y, Gustilo EM, Harris KA, Jones CN, Lusic H, Kaiser RJ, Delaney MO, Spremulli LL, Deiters A, Agris PF. The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons. J Mol Biol; 406(2):257–74; PMID: 21168417; https://dx.doi.org/10.1016/j.jmb.2010.11.042
  • Powell CA, Nicholls TJ, Minczuk M. Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease. Front Genet 2015; 6:79; PMID: 25806043; https://dx.doi.org/10.3389/fgene.2015.00079

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