Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1

References

• Schiattarella GG, Hill JA. Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload. Circulation 2015; 131:1435-47; PMID:25901069; http://dx.doi.org/10.1161/CIRCULATIONAHA.115.013894
   PubMed Web of Science ®Google Scholar
• Park CS, Cha H, Kwon EJ, Sreenivasaiah PK, Kim DH. The chemical chaperone 4-phenylbutyric acid attenuates pressure-overload cardiac hypertrophy by alleviating endoplasmic reticulum stress. Biochem Biophys Res Commun 2012; 421:578-84; PMID:22525677; http://dx.doi.org/10.1016/j.bbrc.2012.04.048.
   PubMed Web of Science ®Google Scholar
• Santos CX, Tanaka LY, Wosniak J, Laurindo FR. Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase. Antioxid Redox Signal 2009; 11:2409-27; PMID:19388824; http://dx.doi.org/10.1089/ars.2009.2625.
   PubMed Web of Science ®Google Scholar
• Sag CM, Santos CX, Shah AM. Redox regulation of cardiac hypertrophy. J Mol Cell Cardiol 2014; 73:103-11; PMID:24530760; http://dx.doi.org/10.1016/j.yjmcc.2014.02.002.
   PubMed Web of Science ®Google Scholar
• Groenendyk J, Agellon LB, Michalak M. Coping with endoplasmic reticulum stress in the cardiovascular system. Ann Rev Physiol 2013; 75:49-67; PMID:23020580; http://dx.doi.org/10.1146/annurev-physiol-030212-183707.
   PubMed Web of Science ®Google Scholar
• Lu WW, Zhao L, Zhang JS, Hou YL, Yu YR, Jia MZ, Tang CS, Qi YF. Intermedin1-53 protects against cardiac hypertrophy by inhibiting endoplasmic reticulum stress via activating AMP-activated protein kinase. J Hypertens 2015; 33:1676-87; PMID:26136070; http://dx.doi.org/10.1097/hjh.0000000000000597.
   PubMed Web of Science ®Google Scholar
• Hetz C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat Rev Mol Cell Biol 2012; 13:89-102; PMID:22251901; http://dx.doi.org/10.1038/nrm3270.
   PubMed Web of Science ®Google Scholar
• Wu R, Zhang QH, Lu YJ, Ren K, Yi GH. Involvement of the IRE1alpha-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases. DNA Cell Biol 2015; 34:6-18; PMID:25216212; http://dx.doi.org/10.1089/dna.2014.2552.
   PubMed Web of Science ®Google Scholar
• Jiang D, Niwa M, Koong AC. Targeting the IRE1alpha-XBP1 branch of the unfolded protein response in human diseases. Semin Cancer Biol 2015; 33:48-56; PMID:25986851; http://dx.doi.org/10.1016/j.semcancer.2015.04.010.
   PubMed Web of Science ®Google Scholar
• Duan Q NL, Wang P, Chen C, Yang L, Ma B, Gong W, Cai Z, Zou MH, Wang DW. Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in vivo. Aging Cell 2016; 15:625-33; http://dx.doi.org/doi:10.1111/acel.12460
   PubMed Web of Science ®Google Scholar
• Newton K. RIPK1 and RIPK3: critical regulators of inflammation and cell death. Trends Cell Biol 2015; 25:347-53; PMID:25662614; http://dx.doi.org/10.1016/j.tcb.2015.01.001
   PubMed Web of Science ®Google Scholar
• Murphy JM, Silke J. Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death. EMBO Rep 2014; 15:155-64; PMID:24469330; http://dx.doi.org/10.1002/embr.201337970.
   PubMed Web of Science ®Google Scholar
• Li L, Chen Y, Doan J, Murray J, Molkentin JD, Liu Q. Transforming growth factor beta-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling. Circulation 2014; 130:2162-72; PMID:25278099; http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011195.
   PubMed Web of Science ®Google Scholar
• Luedde M, Lutz M, Carter N, Sosna J, Jacoby C, Vucur M, Gautheron J, Roderburg C, Borg N, Reisinger F, et al. RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction. Cardiovasc Res 2014; 103:206-16; PMID:24920296; http://dx.doi.org/10.1093/cvr/cvu146.
   PubMed Web of Science ®Google Scholar
• Zhang T, Zhang Y, Cui M. CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis. Nat Med 2016; 22:175-82; PMID:26726877; http://dx.doi.org/10.1038/nm.4017.
   PubMed Web of Science ®Google Scholar
• Luan Q, Jin L, Jiang CC, Tay KH, Lai F, Liu XY, Liu YL, Guo ST, Li CY, Yan XG, et al. RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy. Autophagy 2015; 11:975-94; PMID:26018731; http://dx.doi.org/10.1080/15548627.2015.1049800.
   PubMed Web of Science ®Google Scholar
• Estornes Y, Aguileta MA, Dubuisson C, De Keyser J, Goossens V, Kersse K, Samali A, Vandenabeele P, Bertrand MJ. RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions. Cell Death Dis 2014; 5:e1555; PMID:25476903; http://dx.doi.org/10.1038/cddis.2014.523.
   PubMedGoogle Scholar
• Zhao M, Lu L, Lei S, Chai H, Wu S, Tang X, Bao Q, Chen L, Wu W, Liu X. Inhibition of receptor interacting protein kinases attenuates cardiomyocyte hypertrophy induced by palmitic acid. Oxidat Med Cell Longev 2016; 2016:1451676; PMID:27057269; http://dx.doi.org/10.1155/2016/1451676.
   PubMedGoogle Scholar
• Kuroda J, Ago T, Matsushima S, Zhai P, Schneider MD, Sadoshima J. NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart. Proc Natl Acad Sci U S A 2010; 107:15565-70; PMID:20713697; http://dx.doi.org/10.1073/pnas.1002178107
   PubMed Web of Science ®Google Scholar
• Maejima Y, Kuroda J, Matsushima S, Ago T, Sadoshima J. Regulation of myocardial growth and death by NADPH oxidase. J Mol Cell Cardiol 2011; 50:408-16; PMID:21215757; http://dx.doi.org/10.1016/j.yjmcc.2010.12.018.
   PubMed Web of Science ®Google Scholar
• Eletto D, Chevet E, Argon Y, Appenzeller-Herzog C. Redox controls UPR to control redox. J Cell Sci 2014; 127:3649-58; PMID:25107370; http://dx.doi.org/10.1242/jcs.153643.
   PubMed Web of Science ®Google Scholar
• Wu RF, Ma Z, Liu Z, Terada LS. Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation. Mol Cell Biol 2010; 30:3553-68; PMID:20457808; http://dx.doi.org/10.1128/MCB.01445-09.
   PubMed Web of Science ®Google Scholar
• Santos CX, Hafstad AD, Beretta M, Zhang M, Molenaar C, Kopec J, Fotinou D, Murray TV, Cobb AM, Martin D, et al. Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2alpha-mediated stress signaling. EMBO J 2016; 35:319-34; PMID:26742780; http://dx.doi.org/10.15252/embj.201592394.
   PubMed Web of Science ®Google Scholar
• Pedruzzi E, Guichard C, Ollivier V, Driss F, Fay M, Prunet C, Marie JC, Pouzet C, Samadi M, Elbim C, et al. NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells. Mol Cell Biol 2004; 24:10703-17; PMID:15572675; http://dx.doi.org/10.1128/mcb.24.24.10703-10717.2004.
   PubMed Web of Science ®Google Scholar
• Matsushima S, Kuroda J, Ago T, Zhai P, Park JY, Xie LH, Tian B, Sadoshima J. Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy. Circ Res 2013; 112:651-63; PMID:23271793; http://dx.doi.org/10.1161/circresaha.112.279760.
   PubMed Web of Science ®Google Scholar
• Byrne JA, Grieve DJ, Bendall JK, Li JM, Gove C, Lambeth JD, Cave AC, Shah AM. Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ Res 2003; 93:802-5; PMID:14551238; http://dx.doi.org/10.1161/01.res.0000099504.30207.f5.
   PubMed Web of Science ®Google Scholar
• Zeng SY, Chen X, Chen SR, Li Q, Wang YH, Zou J, Cao WW, Luo JN, Gao H, Liu PQ. Upregulation of Nox4 promotes angiotensin II-induced epidermal growth factor receptor activation and subsequent cardiac hypertrophy by increasing ADAM17 expression. Can J Cardiol 2013; 29:1310-9; PMID:23850346; http://dx.doi.org/10.1016/j.cjca.2013.04.026.
   PubMed Web of Science ®Google Scholar
• Zhao QD, Viswanadhapalli S, Williams P, Shi Q, Tan C, Yi X, Bhandari B, Abboud HE. NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFkappaB signaling pathways. Circulation 2015; 131:643-55; PMID:25589557; http://dx.doi.org/10.1161/circulationaha.114.011079.
   PubMed Web of Science ®Google Scholar
• Ago T, Kuroda J, Pain J, Fu C, Li H, Sadoshima J. Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ Res 2010; 106:1253-64; PMID:20185797; http://dx.doi.org/10.1161/circresaha.109.213116.
   PubMed Web of Science ®Google Scholar
• Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circ Res 2006; 99:275-82; PMID:16794188; http://dx.doi.org/10.1161/01.RES.0000233317.70421.03
   PubMed Web of Science ®Google Scholar
• Wang ZV, Deng Y, Gao N, Pedrozo Z, Li DL, Morales CR, Criollo A, Luo X, Tan W, Jiang N, et al. Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway. Cell 2014; 156:1179-92; PMID:24630721; http://dx.doi.org/10.1016/j.cell.2014.01.014.
   PubMed Web of Science ®Google Scholar
• Bhandari P, Song M, Dorn GW, 2nd. Dissociation of mitochondrial from sarcoplasmic reticular stress in Drosophila cardiomyopathy induced by molecularly distinct mitochondrial fusion defects. J Mol Cell Cardiol 2015; 80:71-80; PMID:25555803; http://dx.doi.org/10.1016/j.yjmcc.2014.12.018.
   PubMed Web of Science ®Google Scholar
• Iwakoshi NN, Lee AH, Glimcher LH. The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response. Immunol Rev 2003; 194:29-38; PMID:12846805
   PubMed Web of Science ®Google Scholar
• Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 2008; 134:743-56; PMID:18775308; http://dx.doi.org/10.1016/j.cell.2008.07.021.
   PubMed Web of Science ®Google Scholar
• Hess DA, Humphrey SE, Ishibashi J, Damsz B, Lee AH, Glimcher LH, Konieczny SF. Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology 2011; 141:1463-72; PMID:21704586; http://dx.doi.org/10.1053/j.gastro.2011.06.045.
   PubMed Web of Science ®Google Scholar
• Song J, Zhu Y, Li J, Liu J, Gao Y, Ha T, Que L, Liu L, Zhu G, Chen Q, et al. Pellino1-mediated TGF-beta1 synthesis contributes to mechanical stress induced cardiac fibroblast activation. J Mol Cell Cardiol 2015; 79:145-56; PMID:25446187; http://dx.doi.org/10.1016/j.yjmcc.2014.11.006.
   PubMed Web of Science ®Google Scholar
• Jiang Q, Fu X, Tian L, Chen Y, Yang K, Chen X, Zhang J, Lu W, Wang J. NOX4 mediates BMP4-induced upregulation of TRPC1 and 6 protein expressions in distal pulmonary arterial smooth muscle cells. PloS One 2014; 9:e107135; PMID:25203114; http://dx.doi.org/10.1371/journal.pone.0107135.
   PubMedGoogle Scholar