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Prohibitin promotes androgen receptor activation in ER-positive breast cancer

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Pages 776-784 | Received 06 Jan 2017, Accepted 08 Feb 2017, Published online: 24 Mar 2017

References

  • Nijtmans LG, Artal SM, Grivell LA, Coates PJ. The mitochondrial PHB complex: Roles in mitochondrial respiratory complex assembly, ageing and degenerative disease. Cell Mol Life Sci 2002; 59:143-55; PMID:11852914; http://dx.doi.org/10.1007/s00018-002-8411-0
  • Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, Rapp UR, Rudel T. Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration. Nat Cell Biol 2005; 7:837-43; PMID:16041367; http://dx.doi.org/10.1038/ncb1283
  • Coates PJ, Jamieson DJ, Smart K, Prescott AR, Hall PA. The prohibitin family of mitochondrial proteins regulate replicative lifespan. Curr Biol 1997; 7:607-10; PMID:9259555; http://dx.doi.org/10.1016/S0960-9822(06)00261-2
  • McClung JK, Jupe ER, Liu XT, Dell'Orco RT. Prohibitin: Potential role in senescence, development, and tumor suppression. Exp Gerontol 1995; 30:99-124; PMID:8591812; http://dx.doi.org/10.1016/0531-5565(94)00069-7
  • Choi D, Lee SJ, Hong S, Kim IH, Kang S. Prohibitin interacts with RNF2 and regulates E2F1 function via dual pathways. Oncogene 2008; 27:1716-25; PMID:17873902; http://dx.doi.org/10.1038/sj.onc.1210806
  • Wang S, Fusaro G, Padmanabhan J, Chellappan SP. Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression. Oncogene 2002; 21:8388-96; PMID:12466959; http://dx.doi.org/10.1038/sj.onc.1205944
  • Gamble SC, Odontiadis M, Waxman J, Westbrook JA, Dunn MJ, Wait R, Lam EW, Bevan CL. Androgens target prohibitin to regulate proliferation of prostate cancer cells. Oncogene 2004; 23:2996-3004; PMID:14968116; http://dx.doi.org/10.1038/sj.onc.1207444
  • He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. A repressive role for prohibitin in estrogen signaling. Mol Endocrinol 2008; 22:344-60; PMID:17932104; http://dx.doi.org/10.1210/me.2007-0400
  • Wang S, Zhang B, Faller DV. BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists. EMBO J 2004; 23:2293-303; PMID:15141164; http://dx.doi.org/10.1038/sj.emboj.7600231
  • Dai Y, Ngo D, Jacob J, Forman LW, Faller DV. Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes. Carcinogenesis 2008; 29:1725-33; PMID:18487222; http://dx.doi.org/10.1093/carcin/bgn117
  • Dart DA, Spencer-Dene B, Gamble SC, Waxman J, Bevan CL. Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours. Endocr Relat Cancer 2009; 16:1157-69; PMID:19635783; http://dx.doi.org/10.1677/ERC-09-0028
  • Dart DA, Brooke GN, Sita-Lumsden A, Waxman J, Bevan CL. Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens. Oncogene 2012; 31:4588-98; PMID:22179832; http://dx.doi.org/10.1038/onc.2011.591
  • Fletcher CE, Dart DA, Sita-Lumsden A, Cheng H, Rennie PS, Bevan CL. Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer. Hum Mol Genet 2012; 21:3112-27; PMID:22505583; http://dx.doi.org/10.1093/hmg/dds139
  • Hickey TE, Robinson JL, Carroll JS, Tilley WD. Minireview: The androgen receptor in breast tissues: Growth inhibitor, tumor suppressor, oncogene? Mol Endocrinol 2012; 26:1252-67; PMID:22745190; http://dx.doi.org/10.1210/me.2012-1107
  • Margolis RN, Evans RM, O'Malley BW, Consortium NA. The nuclear receptor signaling atlas: Development of a functional atlas of nuclear receptors. Mol Endocrinol 2005; 19:2433-6; PMID:16051673; http://dx.doi.org/10.1210/me.2004-0461
  • Peters AA, Buchanan G, Ricciardelli C, Bianco-Miotto T, Centenera MM, Harris JM, Jindal S, Segara D, Jia L, Moore NL, et al. Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer. Cancer Res 2009; 69:6131-40; PMID:19638585; http://dx.doi.org/10.1158/0008-5472.CAN-09-0452
  • Szelei J, Jimenez J, Soto AM, Luizzi MF, Sonnenschein C. Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor. Endocrinology 1997; 138:1406-12; PMID:9075695; http://dx.doi.org/10.1210/endo.138.4.5047
  • Ni M, Chen Y, Lim E, Wimberly H, Bailey ST, Imai Y, Rimm DL, Liu XS, Brown M. Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell 2011; 20:119-31; PMID:21741601; http://dx.doi.org/10.1016/j.ccr.2011.05.026
  • Niemeier LA, Dabbs DJ, Beriwal S, Striebel JM, Bhargava R. Androgen receptor in breast cancer: Expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation. Mod Pathol 2010; 23:205-12; PMID:19898421; http://dx.doi.org/10.1038/modpathol.2009.159
  • Terashima M, Kim KM, Adachi T, Nielsen PJ, Reth M, Kohler G, Lamers MC. The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. EMBO J 1994; 13:3782-92; PMID:8070406
  • Roskams AJ, Friedman V, Wood CM, Walker L, Owens GA, Stewart DA, Altus MS, Danner DB, Liu XT, McClung JK. Cell cycle activity and expression of prohibitin mRNA. J Cell Physiol 1993; 157:289-95; PMID:8227162; http://dx.doi.org/10.1002/jcp.1041570211
  • Fusaro G, Dasgupta P, Rastogi S, Joshi B, Chellappan S. Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling. J Biol Chem 2003; 278:47853-61; PMID:14500729; http://dx.doi.org/10.1074/jbc.M305171200
  • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001; 1:34-45; PMID:11900250; http://dx.doi.org/10.1038/35094009
  • Gyorffy B, Surowiak P, Budczies J, Lanczky A. Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer. PLoS One 2013; 8:e82241; PMID:24367507; http://dx.doi.org/10.1371/journal.pone.0082241
  • Chander H, Halpern M, Resnick-Silverman L, Manfredi JJ, Germain D. Skp2B attenuates p53 function by inhibiting prohibitin. EMBO Rep 2010; 11:220-5; PMID:20134482; http://dx.doi.org/10.1038/embor.2010.2
  • Lai J, Nie W, Zhang W, Wang Y, Xie R, Wang Y, Gu J, Xu J, Song W, Yang F. Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast cancer. Oncotarget 2014; 5:6909-22; PMID:25071010; http://dx.doi.org/10.18632/oncotarget.2230
  • Zhang W, Luo J, Chen F, Yang F, Song W, Zhu A, Guan X. BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner. Oncotarget 2015; 6:7608-18; PMID:25797244; http://dx.doi.org/10.18632/oncotarget.3263
  • Zhang W, Luo J, Yang F, Wang Y, Yin Y, Strom A, Gustafsson JÅ, Guan X. BRCA1 inhibits AR-mediated proliferation of breast cancer cells through the activation of SIRT1. Sci Rep 2016; 6:22034; PMID:26902145; http://dx.doi.org/10.1038/srep22034
  • Zhang W, Cao L, Sun Z, Xu J, Tang L, Chen W, Luo J, Yang F, Wang Y, Guan X. Skp2 is over-expressed in breast cancer and promotes breast cancer cell proliferation. Cell Cycle 2016; 15:1344-51; PMID:27111245; http://dx.doi.org/10.1080/15384101.2016.1160986

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