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Editorials: Cell Cycle Features

Versatility of DGCR8 controls stem cell fate

ORCID Icon, ORCID Icon & ORCID Icon
Pages 729-730 | Received 15 Feb 2017, Accepted 19 Feb 2017, Published online: 27 Mar 2017

References

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  • Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 2007; 39:380-5; PMID:17259983; http://dx.doi.org/10.1038/ng1969
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  • Herbert KM, Pimienta G, DeGregorio SJ, Alexandrov A, Steitz JA. Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile. Cell Rep 2013; 5:1070-81; PMID:24239349; http://dx.doi.org/10.1016/j.celrep.2013.10.017
  • Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, Wan X, Pavlidis P, Mills A A, Karayiorgou M, et al. Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet 2008; 40:751-60; PMID:18469815; http://dx.doi.org/10.1038/ng.138

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