References
- Duncan JS, Whittle MC, Nakamura K, Abell AN, Midland AA, Zawistowski JS, Johnson NL, Granger DA, Jordan NV, Darr DB, et al. Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. Cell 2012; 149:307-21; PMID:22500798; http://dx.doi.org/10.1016/j.cell.2012.02.053
- Stuhlmiller TJ, Miller SM, Zawistowski JS, Nakamura K, Beltran AS, Duncan JS, Angus SP, Collins KAL, Granger DA, Reuther RA, et al. Inhibition of lapatinib-induced kinome reprogramming in ERBB2-positive breast cancer by targeting BET family bromodomains. Cell Rep 2015; 11:390-404; PMID:25865888; http://dx.doi.org/10.1016/j.celrep.2015.03.037
- Stratikopoulos EE, Dendy M, Szabolcs M, Khaykin AJ, Lefebvre C, Zhou MM, Parsons R. Kinase and BET inhibitors together clamp inhibition of PI3K signaling and overcome resistance to therapy. Cancer Cell 2015; 27:837-51; PMID:26058079; http://dx.doi.org/10.1016/j.ccell.2015.05.006
- Zawistowski JS, Bevill SM, Goulet DR, Stuhlmiller TJ, Beltran AS, Olivares-Quintero JF, Singh D, Sciaky N, Parker JS, Rashid NU, et al. Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacological targeting of the P-TEFb complex. Cancer Discov 2017; 7(3):302–321; PMID:28108460; http://dx.doi.org/10.1158/2159-8290.CD-16-0653
- Lovén J, Hoke HA, Lin CY, Lau A, Orlando DA, Vakoc CR, Bradner JE, Lee TI, Young RA. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell 2013; 153:320-34; PMID:23582323; http://dx.doi.org/10.1016/j.cell.2013.03.036
- Brown JD, Lin CY, Duan Q, Griffin G, Federation AJ, Paranal RM, Bair S, Newton G, Lichtman AH, Kung AL, et al. NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis. Mol Cell 2014; 56:219-31; PMID:25263595; http://dx.doi.org/10.1016/j.molcel.2014.08.024
- Nabet B, Ó Broin P, Reyes JM, Shieh K, Lin CY, Will CM, Popovic R, Ezponda T, Bradner JE, Golden AA, et al. Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape. Cell Rep 2015; 12:1300-13; PMID:26279576; http://dx.doi.org/10.1016/j.celrep.2015.06.078