1,081
Views
3
CrossRef citations to date
0
Altmetric
Editorials: Cell Cycle Features

mTORC1 promotes Schwann cell cycling and myelinogenesis

&
Pages 1637-1638 | Received 30 Jun 2017, Accepted 08 Jul 2017, Published online: 24 Aug 2017

References

  • Nave KA. Myelination and support of axonal integrity by glia. Nature. 2010;468:244-52. doi:10.1038/nature09614. PMID:21068833.
  • Beirowski B, Wong KM, Babetto E, Milbrandt J. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. Proc Natl Acad Sci U S A. 2017;114:E4261-70. doi:10.1073/pnas.1620761114. PMID:28484008.
  • Laplante M, Sabatini DM. mTOR Signaling in Growth Control and Disease. Cell. 2012;149:274-93. doi:10.1016/j.cell.2012.03.017. PMID:22500797.
  • Rosner M, Freilinger A, Hanneder M, Fujita N, Lubec G, Tsuruo T, Hengstschläger M. p27Kip1 localization depends on the tumor suppressor protein tuberin. Hum Mol Genet. 2007;16:1541-56. doi:10.1093/hmg/ddm103. PMID:17470459.
  • Wang X, Proud CG. Nutrient control of TORC1, a cell-cycle regulator. Trends Cell Biol. 2009;19:260-7. doi:10.1016/j.tcb.2009.03.005. PMID:19419870.
  • Dowling RJ, Topisirovic I, Alain T, Bidinosti M, Fonseca BD, Petroulakis E, Wang X, Larsson O, Selvaraj A, Liu Y, Kozma SC, Thomas G, Sonenberg N. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. Science. 2010;328:1172-76. doi:10.1126/science.1187532. PMID:20508131.
  • Luo Y, Marx SO, Kiyokawa H, Koff A, Massagué J, Marks AR. Rapamycin resistance tied to defective regulation of p27Kip1. Mol Cell Biol. 1996;16:6744-51. PMID:8943329.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.