TFPI2AS1, a novel lncRNA that inhibits cell proliferation and migration in lung cancer

References

• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin. 2014;64:9-29. doi:10.3322/caac.21208. PMID:24399786
   PubMed Web of Science ®Google Scholar
• Seve P, Reiman T, Dumontet C. The role of betaIII tubulin in predicting chemoresistance in non-small cell lung cancer. Lung Cancer. 2010;67:136-43. doi:10.1016/j.lungcan.2009.09.007. PMID:19828208
   PubMed Web of Science ®Google Scholar
• Raungrut P, Wongkotsila A, Lirdprapamongkol K, Svasti J, Geater SL, Phukaoloun M, Suwiwat S, Thongsuksai P. Prognostic significance of 14-3-3gamma overexpression in advanced non-small cell lung cancer. Asian Pacific journal of cancer prevention : APJCP. 2014;15:3513-8. doi:10.7314/APJCP.2014.15.8.3513. PMID:24870749
   PubMedGoogle Scholar
• Gutschner T, Diederichs S. The hallmarks of cancer: a long non-coding RNA point of view. RNA biology. 2012;9:703-19. doi:10.4161/rna.20481. PMID:22664915
   PubMed Web of Science ®Google Scholar
• Kazemzadeh M, Safaralizadeh R, Orang AV. LncRNAs: emerging players in gene regulation and disease pathogenesis. J Genet. 2015;94:771-84. doi:10.1007/s12041-015-0561-6. PMID:26690535
   PubMed Web of Science ®Google Scholar
• Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010;464:1071-6. doi:10.1038/nature08975. PMID:20393566
   PubMed Web of Science ®Google Scholar
• Huarte M. The emerging role of lncRNAs in cancer. Nat Med. 2015;21:1253-61. doi:10.1038/nm.3981. PMID:26540387
   PubMed Web of Science ®Google Scholar
• Mourtada-Maarabouni M, Pickard MR, Hedge VL, Farzaneh F, Williams GT. GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene. 2009;28:195-208. doi:10.1038/onc.2008.373. PMID:18836484
   PubMed Web of Science ®Google Scholar
• Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP. Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci Signal. 2010;3:ra8. doi:10.1126/scisignal.2000568. PMID:20124551
   PubMed Web of Science ®Google Scholar
• Xu G, Chen J, Pan Q, Huang K, Pan J, Zhang W, Yu F, Zhou T, Wang Y. Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. PloS One. 2014;9:e104044. doi:10.1371/journal.pone.0104044. PMID:25089627
   PubMed Web of Science ®Google Scholar
• Gibb EA, Brown CJ, Lam WL. The functional role of long non-coding RNA in human carcinomas. Mol Cancer. 2011;10:38. doi:10.1186/1476-4598-10-38. PMID:21489289
   PubMed Web of Science ®Google Scholar
• Han L, Kong R, Yin DD, Zhang EB, Xu TP, De W, Shu YQ. Low expression of long noncoding RNA GAS6-AS1 predicts a poor prognosis in patients with NSCLC. Med Oncol. 2013;30:694. doi:10.1007/s12032-013-0694-5. PMID:23979857
   PubMed Web of Science ®Google Scholar
• Yang Y, Li H, Hou S, Hu B, Liu J, Wang J. The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell. PloS One. 2013;8:e65309. doi:10.1371/journal.pone.0065309. PMID:23741487
   PubMed Web of Science ®Google Scholar
• Wei MM, Zhou YC, Wen ZS, Zhou B, Huang YC, Wang GZ, Zhao XC, Pan HL, Qu LW, Zhang J, et al. Long non-coding RNA stabilizes the Y-box-binding protein 1 and regulates the epidermal growth factor receptor to promote lung carcinogenesis. Oncotarget. 2016;7:59556-71. doi:10.18632/oncotarget.10006. PMID:27322209
   PubMed Web of Science ®Google Scholar
• Li D, Song L, Wen Z, Li X, Jie J, Wang Y, Peng L. Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis- eQTL locus contributing more to the susceptibility of lung cancer. Oncotarget. 2016;7:35813-7. doi:10.18632/oncotarget.8411. PMID:27166266
   PubMed Web of Science ®Google Scholar
• Shi X, Ma C, Zhu Q, Yuan D, Sun M, Gu X, Wu G, Lv T, Song Y. Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer. Oncotarget. 2016;7:25558-75. doi:10.18632/oncotarget.8338. PMID:27027352
   PubMed Web of Science ®Google Scholar
• Lavergne M, Jourdan ML, Blechet C, Guyetant S, Pape AL, Heuze-Vourc'h N, Courty Y, Lerondel S, Sobilo J, Iochmann S, et al. Beneficial role of overexpression of TFPI-2 on tumour progression in human small cell lung cancer. FEBS Open Bio. 2013;3:291-301. doi:10.1016/j.fob.2013.06.004. PMID:23905012
   PubMed Web of Science ®Google Scholar
• Wang S, Xiao X, Zhou X, Huang T, Du C, Yu N, Mo Y, Lin L, Zhang J, Ma N, et al. TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma. BMC Cancer. 2010;10:617. doi:10.1186/1471-2407-10-617. PMID:21062455
   PubMed Web of Science ®Google Scholar
• Sierko E, Wojtukiewicz MZ, Kisiel W. The role of tissue factor pathway inhibitor-2 in cancer biology. Semin Throm Hemost. 2007;33:653-9. doi:10.1055/s-2007-991532. PMID:18000791
   PubMed Web of Science ®Google Scholar
• Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev. 1993;7:812-21. doi:10.1101/gad.7.5.812. PMID:8491378
   PubMed Web of Science ®Google Scholar
• Tsai LH, Lees E, Faha B, Harlow E, Riabowol K. The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene. 1993;8:1593-602. PMID:8502482
   PubMed Web of Science ®Google Scholar
• Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, Isakoff SJ, Ciciliano JC, Wells MN, Shah AM, et al. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 2013;339:580-4. doi:10.1126/science.1228522. PMID:23372014
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. Ca A Cancer Journal for Clinicians. 2016;66:10-29.
   Web of Science ®Google Scholar
• Fu X, Li H, Liu C, Hu B, Li T, Wang Y. Long noncoding RNA AK126698 inhibits proliferation and migration of non-small cell lung cancer cells by targeting Frizzled-8 and suppressing Wnt/beta-catenin signaling pathway. OncoTargets Ther. 2016;9:3815-27. doi:10.2147/OTT.S100633. PMID:27445486
   PubMed Web of Science ®Google Scholar
• Mercer TR, Dinger ME, Mattick JS. Long non-coding RNAs: insights into functions. Nat Rev Gen. 2009;10:155-9. doi:10.1038/nrg2521. PMID:19188922
   PubMed Web of Science ®Google Scholar
• Zhao X, Liu M, Zhang J, Zhang R, Zhang Q, Tan X. Long noncoding RNA CPS1-IT1 suppresses cell proliferation and metastasis in human lung cancer. Oncol Res. 2017;25:373-380. doi:10.3727/096504016X14741486659473. PMID:27662619
   PubMed Web of Science ®Google Scholar
• She K, Huang J, Zhou H, Huang T, Chen G, He J. lncRNA-SNHG7 promotes the proliferation, migration and invasion and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression. Oncol Rep. 2016. doi:10.3892/or.2016.5105.
   Web of Science ®Google Scholar
• Meola N, Pizzo M, Alfano G, Surace EM, Banfi S. The long noncoding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retina. RNA. 2012;18:111-23. doi:10.1261/rna.029454.111. PMID:22128341
   PubMed Web of Science ®Google Scholar
• Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet. 2011;43:621-9. doi:10.1038/ng.848. PMID:21642992
   PubMed Web of Science ®Google Scholar
• Jimenez B, Tiana M, Del Peso L. lnc RNAs, hypoxia and metastasis. Oncoscience 2015;2:795-6. PMID:26682249
   PubMedGoogle Scholar
• Huarte M. The emerging role of lncRNAs in cancer. Nat Med. 2015;21:1253-61. doi:10.1038/nm.3981. PMID:26540387
   PubMed Web of Science ®Google Scholar
• Niland CN, Merry CR, Khalil AM. Emerging Roles for Long Non-Coding RNAs in Cancer and Neurological Disorders. Front Genet. 2012;3:25. doi:10.3389/fgene.2012.00025. PMID:22375145
   PubMedGoogle Scholar
• Zhang H, Chen Z, Wang X, Huang Z, He Z, Chen Y. Long non-coding RNA: a new player in cancer. J Hematol Oncol. 2013;6:37. doi:10.1186/1756-8722-6-37.
   PubMed Web of Science ®Google Scholar
• Qi P, Du X. The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013;26:155-65. doi:10.1038/modpathol.2012.160. PMID:22996375
   PubMed Web of Science ®Google Scholar
• Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov. 2011;1:391-407. doi:10.1158/2159-8290.CD-11-0209. PMID:22096659
   PubMed Web of Science ®Google Scholar
• Chand HS, Du X, Ma D, Inzunza HD, Kamei S, Foster D, Brodie S, Kisiel W. The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic mice. Blood. 2004;103:1069-77. doi:10.1182/blood-2003-06-1930. PMID:14525759
   PubMed Web of Science ®Google Scholar
• Visconti R, Della Monica R, Grieco D. Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword. J Exp Clin Cancer Res. 2016;35:153. doi:10.1186/s13046-016-0433-9. PMID:27670139
   PubMed Web of Science ®Google Scholar
• Toker A, Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res. 2006;66:3963-6. doi:10.1158/0008-5472.CAN-06-0743. PMID:16618711
   PubMed Web of Science ®Google Scholar
• Faes S, Dormond O. PI3K and AKT: Unfaithful Partners in Cancer. Int J Mol Sci. 2015;16:21138-52. doi:10.3390/ijms160921138. PMID:26404259
   PubMed Web of Science ®Google Scholar
• Rollin J, Iochmann S, Blechet C, Hube F, Regina S, Guyetant S, Lemarie E, Reverdiau P, Gruel Y. Expression and methylation status of tissue factor pathway inhibitor-2 gene in non-small-cell lung cancer. Br J Cancer. 2005;92:775-83. doi:10.1038/sj.bjc.6602298. PMID:15685245
   PubMed Web of Science ®Google Scholar
• Wu D, Xiong L, Wu S, Jiang M, Lian G, Wang M. TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer. Lung Cancer. 2012;76:106-11. doi:10.1016/j.lungcan.2011.09.005. PMID:21983100
   PubMed Web of Science ®Google Scholar
• Zhang CL, Zhu KP, Ma XL. Antisense lncRNA FOXC2-AS1 promotes doxorubicin resistance in osteosarcoma by increasing the expression of FOXC2. Cancer Lett. 2017;396:66-75. doi:10.1016/j.canlet.2017.03.018. PMID:28323030
   PubMed Web of Science ®Google Scholar
• Liu W, Ma J, Cheng Y, Zhang H, Luo W, Zhang H. HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells. Breast Cancer (Dove Med Press). 2016;8:223-9. PMID:27920576
   PubMed Web of Science ®Google Scholar
• Koeslag JH, Saunders PT, Terblanche E. A reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex. J Physiol. 2003;549:333-46. doi:10.1113/jphysiol.2002.037895. PMID:12717005
   PubMed Web of Science ®Google Scholar