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Research Paper

Interaction of p53 and ASPPs regulates rhesus monkey embryonic stem cells conversion to neural fate concomitant with apoptosis

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Pages 1146-1153 | Received 13 Dec 2017, Accepted 08 Apr 2018, Published online: 25 Jul 2018

References

  • Li T, Kon N, Jiang L, et al. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell. 2012;149:1269–1283.
  • Meek DW. The p53 response to DNA damage. DNA Repair. 2004;3:1049–1056.
  • Bergamaschi D, Samuels Y, Jin B, et al. ASPP1 and ASPP2: common activators of p53 family members. Mol Cell Biol. 2004;24:1341–1350.
  • Bergamaschi D, Samuels Y, O’Neil NJ, et al. iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human. Nat Genet. 2003;33:162–167.
  • Vives V, Slee EA, Lu X. ASPP2: a gene that controls life and death in vivo. Cell Cycle (Georgetown, Tex). 2006;5:2187–2190.
  • Imai H, Kano K, Fujii W, et al. Tetraploid embryonic stem cells maintain pluripotency and differentiation potency into three germ layers. PloS One. 2015;10:e0130585.
  • Thomson JA, Kalishman J, Golos TG, et al. Isolation of a primate embryonic stem cell line. Proc Natl Acad Sci USA. 1995;92:7844–7848.
  • Aladjem MI, Spike BT, Rodewald LW, et al. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr Biol. 1998;8:145–155.
  • Solozobova V, Rolletschek A, Blattner C. Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage. BMC Cell Biol. 2009;10:46.
  • Solozobova V, Blattner C. Regulation of p53 in embryonic stem cells. Exp Cell Res. 2010;316:2434–2446.
  • Lin T, Chao C, Saito S, et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol. 2005;7:165–171.
  • Hernandez-Borrero LJ, Zhang S, Lulla A, et al. CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA. Cell Cycle. 2018 ;17(5):557–567.
  • Qin H, Yu T, Qing T, et al. Regulation of apoptosis and differentiation by p53 in human embryonic stem cells. J Biol Chem. 2007;282:5842–5852.
  • He Z, Li J, Zhen C, et al. Knockdown of p53 by RNAi in ES cells facilitates RA-induced differentiation into muscle cells. Biochem Biophys Res Commun. 2005;335:676–683.
  • Chen R, Li R, Ji W, et al. Primary research on changes of ASPP family in the process of neural differentiation from Rhesus embryonic stem cells. J Univ Sci Technol China. 2010;10:0253–2778.
  • Chen X, Li T, Li X, et al. Neural progenitors derived from monkey embryonic stem cells in a simple monoculture system. Reprod BioMed. 2009;19(3):426–433.
  • Utikal J, Polo JM, Stadtfeld M, et al. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature. 2009;460:1145–1148.
  • Li H, Collado M, Villasante A, et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature. 2009;460:1136–1139.
  • Sottocornola R, Royer C, Vives V, et al. ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. Dev Cell. 2010;19:126–137.
  • Heese K, Low JW, Inoue N. Nerve growth factor, neural stem cells and Alzheimer’s disease. Neuro-Signals. 2006;15:1–12.
  • Hock C, Heese K, Hulette C, et al. Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol. 2000;57:846–851.
  • Du ZW, Zhang SC. Neural differentiation from embryonic stem cells: which way? Stem Cells Dev. 2004;13:372–381.
  • Hu BY, Du ZW, Li XJ, et al. Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects. Development (Cambridge, England). 2009;136:1443–1452.
  • Li T, Zheng J, Xie Y, et al. Transplantable neural progenitor populations derived from rhesus monkey embryonic stem cells. Stem Cells (Dayton, Ohio). 2005;23:1295–1303.
  • Levenstein ME, Ludwig TE, Xu RH, et al. Basic fibroblast growth factor support of human embryonic stem cell self-renewal. Stem Cells (Dayton, Ohio). 2006;24:568–574.
  • Ludwig TE, Bergendahl V, Levenstein ME, et al. Feeder-independent culture of human embryonic stem cells. Nat Methods. 2006;3:637–646.
  • Elkabetz Y, Panagiotakos G, Al Shamy G, et al. ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev. 2008;22:152–165.
  • Elkabetz Y, Studer L. Human ESC-derived neural rosettes and neural stem cell progression. Cold Spring Harb Symp Quant Biol. 2008;73:377–387.
  • Wianny F, Bernat A, Huissoud C, et al. Derivation and cloning of a novel rhesus embryonic stem cell line stably expressing tau-green fluorescent protein. Stem Cells (Dayton, Ohio). 2008;26:1444–1453.
  • Chen Y, Wang Z, Xie Y, et al. Folic acid deficiency inhibits neural rosette formation and neuronal differentiation from rhesus monkey embryonic stem cells. J Neurosci Res. 2012;90:1382–1391.

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