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Research Paper

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability

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Pages 1407-1421 | Received 20 Mar 2019, Accepted 08 May 2019, Published online: 26 May 2019

References

  • Eissenberg JC, James TC, Foster-Hartnett DM, et al. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1990;87:9923–9927.
  • James TC, Elgin SC. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol Cell Biol. 1986;6:3862–3872.
  • Eissenberg JC, Elgin SCR. The HP1 protein family: getting a grip on chromatin. Curr Opin Genet Dev. 2000;10:204–210.
  • Lomberk G, Wallrath L, Urrutia R. The Heterochromatin Protein 1 family. Genome Biol. 2006;7:228.
  • Stewart MD, Li J, Wong J. Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment. Mol Cell Biol. 2005;25:2525–2538.
  • Wolfgang Fischle BST, Dormann HL, Ueberheide BM, et al. Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation. Nature. 2005;438:1116–1122.
  • Eissenberg JC, Elgin SCR. HP1a: a structural chromosomal protein regulating transcription. Trends Genet. 2014;30:103–110.
  • Nestorov P, Tardat M, Peters AHFM. Current topics in developmental biology: Epigenetics and development, Vol. 104, ed Edith Heard. San Diego (CA): Academic Press; 2013. p. 243–291.
  • Dinant C, Luijsterburg MS. The emerging role of HP1 in the DNA damage response. Mol Cell Biol. 2009;29:6335–6340.
  • Prendergast JMGHAL. Mitotic mysteries: the case of HP1. Dev Cell. 2016;36:477–478.
  • So Hee K, Jerry LW. The heterochromatin protein 1 (HP1) family: put away a bias toward HP1. Mol Cells. 2008;26:217–227.
  • Wu W, Togashi Y, Johmura Y, et al. HP1 regulates the localization of FANCJ at sites of DNA double‐strand breaks. Cancer Sci. 2016;107:1406–1415.
  • Ainsztein AM, Kandels-Lewis SE, Mackay AM, et al. INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. J Cell Biol. 1998;143:1763–1774.
  • Carmena M, Platani PX, Salloum Z, et al. The chromosomal passenger complex activates polo kinase at centromeres. PLoS Biol. 2012;10:e1001250.
  • Mar Carmena MW, Funabiki H, Earnshaw WC. The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol. 2012;13:789–803.
  • Gassmann R, Carvalho A, Henzing AJ, et al. Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol. 2004;166:179–191.
  • Liu X, Song Z, Huo Y, et al. Chromatin protein HP1α interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex. J Biol Chem. 2014;289:20638–20649.
  • Abe Y, Sako K, Takagaki K, et al. HP1-assisted AURORA B kinase activity prevents chromosome segregation errors. Dev Cell. 2016;36:487–497.
  • Kang J, Chaudhary J, Dong H, et al. Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells. Mol Biol Cell. 2011;22:1181–1190.
  • Canzio D, Chang EY, Shankar S, et al. Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Mol Cell. 2011;41:67–81.
  • Chu L, Huo Y, Liu X, et al. The spatiotemporal dynamics of chromatin protein HP1α is essential for accurate chromosome segregation during cell division. J Biol Chem. 2014;289:26249–26262.
  • Chakraborty A, Prasanth KV, Prasanth SG. Dynamic phosphorylation of HP1α regulates mitotic progression in human cells. Nat Commun. 2014;5:3445.
  • Hayakawa T, Haraguchi T, Masumoto H, et al. Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase. J Cell Sci. 2003;116:3327.
  • Nishibuchi G, Machida S, Nakagawa R, et al. Mitotic phosphorylation of HP1alpha regulates its cell cycle-dependent chromatin binding. J Biochem. 2018. DOI:10.1093/jb/mvy117.
  • Ma HT, Poon RYC. Cell cycle synchronization: methods and protocols (ed Gaspar Banfalvi). Humana Press; 2011. p. 151–161.
  • Fischle W, Tseng BS, Dormann HL, et al. Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation. Nature. 2005;438:1116.
  • Grzenda A, Leonard P, Seo S, et al. Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression. Epigenetics Chromatin. 2013;6:21.
  • Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nat Methods. 2012;9:671.
  • Costes SV, Daelemans D, Cho EH, et al. Automatic and quantitative measurement of protein-protein colocalization in live cells. Biophys J. 2004;86:3993–4003.
  • Dunn KW, Kamocka MM, McDonald JH. A practical guide to evaluating colocalization in biological microscopy. Am J Physiol Cell Physiol. 2011;300:C723–C742.
  • Skoufias DA, DeBonis S, Saoudi Y, et al. S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. J Biol Chem. 2006;281:17559–17569.
  • van Leuken R, Clijsters L, van Zon W, et al. Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1. PloS One. 2009;4:e5282.
  • Durkin ME, Qian X, Popescu NC, et al. Isolation of mouse embryo fibroblasts. Bio-Protocol. 2013;3:e908.
  • Mathison A, Liebl A, Bharucha J, et al. Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. Pancreatology. 2010;10:505–516.
  • Black BE, Bassett EA. The histone variant CENP-A and centromere specification. Curr Opin Cell Biol. 2008;20:91–100.
  • Black BE, Brock MA, Bedard S, et al. An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes. Proc Natl Acad Sci U S A. 2007;104:5008–5013.
  • Sekulic N, Bassett EA, Rogers DJ, et al. The structure of (CENP-A/H4)(2) reveals physical features that mark centromeres. Nature. 2010;467:347–351.
  • Maiato H, DeLuca J, Salmon ED, et al. The dynamic kinetochore-microtubule interface. J Cell Sci. 2004;117:5461–5477.
  • LeRoy G, Weston JT, Zee BM, et al. Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Mol Cell Proteomics. 2009;8:2432–2442.
  • Lomberk G, Bensi D, Fernandez-Zapico ME, et al. Evidence for the existence of an HP1-mediated subcode within the histone code. Nat Cell Biol. 2006;8:407.
  • Zhang R, Chen W, Adams PD. Molecular dissection of formation of senescence-associated heterochromatin foci. Mol Cell Biol. 2007;27:2343–2358.
  • Ruppert JG, Samejima K, Platani M, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. Embo J. 2018;37:e97677.