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Research Paper

Chrysophanol protects PC12 cells against oxygen glucose deprivation-evoked injury by up-regulating miR-216a

, , , & ORCID Icon
Pages 1433-1442 | Received 12 Nov 2019, Accepted 29 Dec 2019, Published online: 13 May 2020

References

  • Siniscalchi A, Gallelli L, Malferrari G, et al. Cerebral stroke injury: the role of cytokines and brain inflammation. J Basic Clin Physiol Pharmacol. 2014;25:131–137.
  • Mehta SL, Manhas N, Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res Rev. 2007;54:34–66.
  • Gupta YK, Briyal S, Gulati A. Therapeutic potential of herbal drugs in cerebral ischemia. Indian J Physiol Pharmacol. 2010;54:99–122.
  • Ni CH, Yu CS, Lu HF, et al. Chrysophanol‐induced cell death (necrosis) in human lung cancer A549 cells is mediated through increasing reactive oxygen species and decreasing the level of mitochondrial membrane potential. Environ Toxicol. 2014;29:740–749.
  • Chen YC, Shen SC, Lee WR, et al. Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production. Biochem Pharmacol. 2002;64:1713–1724.
  • Agarwal SK, Singh SS, Verma S, et al. Antifungal activity of anthraquinone derivatives from Rheum emodi. J Ethnopharmacol. 2000;72:43–46.
  • Kim DH, Park EK, Bae EA, et al. Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions. Biol Pharm Bull. 2000;23:830–833.
  • Zhao Y, Fang Y, Zhao H, et al. Chrysophanol inhibits endoplasmic reticulum stress in cerebral ischemia and reperfusion mice. Eur J Pharmacol. 2018;818:1–9.
  • Zhao Y, Fang Y, Li J, et al. Neuroprotective effects of Chrysophanol against inflammation in middle cerebral artery occlusion mice. Neurosci Lett. 2016;630:16–22.
  • Zhang J, Yan C, Wang S, et al. Chrysophanol attenuates lead exposure-induced injury to hippocampal neurons in neonatal mice. Neural Regen Res. 2014;9:924–930.
  • Yao S, Tang B, Li G, et al. miR-455 inhibits neuronal cell death by targeting TRAF3 in cerebral ischemic stroke. Neuropsychiatr Dis Treat. 2016;12:3083–3092.
  • Guo D, Ma J, Yan L, et al. Down-regulation of Lncrna MALAT1 attenuates neuronal cell death through suppressing beclin1-dependent autophagy by regulating Mir-30a in cerebral ischemic stroke. Cell Physiol Biochem. 2017;43:182–194.
  • Ding H, Gao S, Wang L, et al. Overexpression of miR-582-5p inhibits the apoptosis of neuronal cells after cerebral ischemic stroke through regulating PAR-1/Rho/Rho Axis. J Stroke Cerebrovasc Dis. 2019;28:149–155.
  • Koturbash I, Zemp F, Kolb B, et al. Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model. Mutat Res Genet Toxicol Environ Mutagen . 2011;722:114–118.
  • Tian YS, Zhong D, Liu QQ, et al. Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2/STAT3-involved apoptosis and inflammatory pathways. J Neurosurg. 2018;130:977–988.
  • Hou Y, Wang K, Wan W, et al. Resveratrol provides neuroprotection by regulating the JAK2/STAT3/PI3K/AKT/mTOR pathway after stroke in rats. Genes Dis. 2018;5:245–255.
  • Xu X, Chua CC, Gao J, et al. Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway. Brain Res. 2008;1227:12–18.
  • Kretz A, Happold CJ, Marticke JK, et al. Erythropoietin promotes regeneration of adult CNS neurons via Jak2/Stat3 and PI3K/AKT pathway activation. Mol Cell Neurosci. 2005;29:569–579.
  • Chiu BY, Chang CP, Lin JW, et al. Beneficial effect of astragalosides on stroke condition using PC12 cells under oxygen glucose deprivation and reperfusion. Cell Mol Neurobiol. 2014;34:825–837.
  • Guo H, Kong S, Chen W, et al. Apigenin mediated protection of OGD-evoked neuron-like injury in differentiated PC12 cells. Neurochem Res. 2014;39:2197–2210.
  • Gaire BP, Jamarkattel-Pandit N, Lee D, et al. Terminalia chebula extract protects OGD-R induced PC12 cell death and inhibits lps induced microglia activation. Molecules. 2013;18:3529–3542.
  • Chang R, Zhou R, Qi X, et al. Protective effects of aloin on oxygen and glucose deprivation-induced injury in PC12 cells. Brain Res Bull. 2016;121:75–83.
  • Zhao Y, Huang Y, Fang Y, et al. Chrysophanol attenuates nitrosative/oxidative stress injury in a mouse model of focal cerebral ischemia/reperfusion. J Pharmacol Sci. 2018;138:16–22.
  • Chae U, Min JS, Leem HH, et al. Chrysophanol suppressed glutamate-induced hippocampal neuronal cell death via regulation of dynamin-related protein 1-dependent mitochondrial fission. Pharmacology. 2017;100:153–160.
  • Yan J, Zheng M, Zhang D. Chrysophanol liposome preconditioning protects against cerebral ischemia-reperfusion injury by inhibiting oxidative stress and apoptosis in mice. Int J Pharmacol. 2014;10:55–68.
  • Zhang N, Zhang X. Chrysophanol inhibits NALP3 inflammasome activation and ameliorates cerebral ischemia/reperfusion in mice. Mediators Inflammation. 2014;2014:370530.
  • Yi G, Liu L, Lv C, et al. Ginsenoside Rg1 defenses PC-12 cells against hydrogen peroxide-caused damage via up-regulation of miR-216a-5p. Life Sci. 2019;236:116948.
  • Xia H, Ooi LL, Hui KM. MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer. Hepatology. 2013;58:629–641.
  • Cui Y, Lu P, Song G, et al. Involvement of PI3K/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis. Food Chem Toxicol. 2016;92:26–37.
  • Tao Y, Yang S, Wu Y, et al. MicroRNA-216a inhibits the metastasis of gastric cancer cells by targeting JAK2/STAT3-mediated EMT process. Oncotarget. 2017;8:88870–88881.
  • Wang J, Chen X, Shen D, et al. A long noncoding RNA NR_045363 controls cardiomyocyte proliferation and cardiac repair. J Mol Cell Cardiol. 2019;127:105–114.
  • Hou BH, Jian ZX, Cui P, et al. miR-216a may inhibit pancreatic tumor growth by targeting JAK2. FEBS Lett. 2015;589:2224–2232.
  • Yan YR, Luo Y, Zhong M, et al. MiR-216a inhibits proliferation and promotes apoptosis of human airway smooth muscle cells by targeting JAK2. J Asthma. 2019;56:938–946.
  • Yuan J, Hong H, Zhang Y, et al. Chrysophanol attenuated isoproterenol-induced cardiac hypertrophy by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. Cell Biol Int. 2019;43:695–705.

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