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Research Paper

Matrine Inhibitory Effect on Self-renewal and Re-sensitization of 5-FU Resistant NSCLC Stem Cells were through Let-7b dependent Downregulation of CCND1

, , , , ORCID Icon, , , , , & ORCID Icon show all
Pages 3249-3259 | Received 31 Oct 2019, Accepted 12 Oct 2020, Published online: 09 Nov 2020

References

  • Chen X, Zhi X, Pan P, et al. Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis. Faseb J. 2017;31:4855–4865.
  • Liao XZ, Tao LT, Liu JH, et al. Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway. Cancer Cell Int. 2017;17:124.
  • Zhang YB, Luo D, Yang L, et al. Matrine-type alkaloids from the roots of sophora flavescens and their antiviral activities against the hepatitis B virus. J Nat Prod. 2018;81(10):2259–2265.
  • An Q, Han C, Zhou Y, et al. Matrine induces cell cycle arrest and apoptosis with recovery of the expression of miR-126 in the A549 non-small cell lung cancer cell line. Mol Med Rep. 2016;14:4042–4048.
  • Gu YY, Chen MH, May BH, et al. Matrine induces apoptosis in multiple colorectal cancer cell lines in vitro and inhibits tumour growth with minimum side effects in vivo via Bcl-2 and caspase-3. Phytomedicine. 2018;51:214–225.
  • Rashid HU, Xu Y, Muhammad Y, et al. Research advances on anticancer activities of matrine and its derivatives: an updated overview. Eur J Med Chem. 2019;161:205–238.
  • Huang H, Wang Q, Du T, et al. Matrine inhibits the progression of prostate cancer by promoting expression of GADD45B. Prostate. 2018;78:327–335.
  • Huang M, Xin W. Matrine inhibiting pancreatic cells epithelial-mesenchymal transition and invasion through ROS/NF-kappaB/MMPs pathway. Life Sci. 2018;192:55–61.
  • Yao Y, Zhao M, Yuan D, et al. Elevated pretreatment serum globulin albumin ratio predicts poor prognosis for advanced non-small cell lung cancer patients. J Thorac Dis. 2014;6:1261–1270.
  • Barta JA, Powell CA, Wisnivesky JP. Global epidemiology of lung cancer. Ann Glob Health. 2019;85(1):8.
  • Du L, Morgensztern D. Chemotherapy for advanced-stage non-small cell lung cancer. Cancer J. 2015;21:366–370.
  • Roush S, Slack FJ. The let-7 family of microRNAs. Trends Cell Biol. 2008;18:505–516.
  • Wang M, Li Y, Xiao G-D, et al. H19 regulation of oestrogen induction of symmetric division is achieved by antagonizing Let-7c in breast cancer stem-like cells. Cell Prolif. 2019;52:e12534.
  • Zhan T, Rindtorff N, Boutros M. Wnt signaling in cancer. Oncogene. 2017;36:1461–1473.
  • Xu C, Xiao G, Zhang B, et al. CCAT1 stimulation of the symmetric division of NSCLC stem cells through activation of the Wnt signalling cascade. Gene Ther. 2018;25:4.
  • Sun X, Xu C, Tang SC, et al. Let-7c blocks estrogen-activated Wnt signaling in induction of self-renewal of breast cancer stem cells. Cancer Gene Ther. 2016;23:83.
  • Czerwonka A, Kalawaj K, Slawinska-Brych A, et al. Anticancer effect of the water extract of a commercial Spirulina (Arthrospira platensis) product on the human lung cancer A549 cell line. Biomed Pharmacothe. 2018;106:292–302.
  • Cruz-Lozano M, Gonzalez-Gonzalez A, Marchal JA, et al. Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/beta-catenin and TGFbeta signaling pathways. 2018.
  • Li J-H, Liu S, Zhou H, et al. starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res. 2014;42:D1, D92–D97.
  • Sancho P, Barneda D, Heeschen C. Hallmarks of cancer stem cell metabolism. Br J Cancer. 2016;114:1305–1312.
  • Binju M, Padilla MA, Singomat T, et al. Mechanisms underlying acquired platinum resistance in high grade serous ovarian cancer - a mini review. Biochim Biophy Acta. 2018;1863:371–378.
  • Steinbichler TB, Dudas J, Skvortsov S, et al. Therapy resistance mediated by cancer stem cells. Seminars in cancer biology. 2018.
  • Li X, Li X, Huang N, et al. A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins. Phytomedicine. 2018;50:73–87.
  • Liao YH, Li CI, Lin CC, et al. Traditional Chinese medicine as adjunctive therapy improves the long-term survival of lung cancer patients. J Cancer Res Clin Oncol 2017;143:2425–2435.
  • Guo S, Chen Y. Matrine is a novel inhibitor of the TMEM16A chloride channel with antilung adenocarcinoma effects. 2018.
  • Jin B, Wang W, Meng XX, et al. Let-7 inhibits self-renewal of hepatocellular cancer stem-like cells through regulating the epithelial-mesenchymal transition and the Wnt signaling pathway. BMC Cancer. 2016;16:863.
  • Sun X, Zhuo XB, Hu YP, et al. A novel matrine derivative WM622 inhibits hepatocellular carcinoma by inhibiting PI3K/AKT signaling pathways. Mol Cell Biochem. 2018;449:47–54.
  • Wu J, Hu G, Dong Y, et al. Matrine induces Akt/mTOR signalling inhibition-mediated autophagy and apoptosis in acute myeloid leukaemia cells. J Cell Mol Med. 2017;21:1171–1181.
  • Zhang JW, Su K, Shi WT, et al. Matrine inhibits the adhesion and migration of BCG823 gastric cancer cells by affecting the structure and function of the vasodilator-stimulated phosphoprotein (VASP). Acta Pharmacol Sin. 2013;34:1084–1092.
  • Feng Y, Ying HY, Qu Y, et al. Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells. Protein Cell. 2016;7:662–672.
  • Gao L, Wang KX, Zhou YZ, et al. Uncovering the anticancer mechanism of compound kushen injection against HCC by integrating quantitative analysis, network analysis and experimental validation. Sci Rep. 2018;8:624.
  • Sun X, Tang SC, Xu C, et al. DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1. J Cell Mol Med. 2015;19:1357–1365.
  • Chandimali N, Huynh DL. MicroRNA-122 negatively associates with peroxiredoxin-II expression in human gefitinib-resistant lung cancer stem cells. Cancer Gene Ther. 2019 Sep; 26(9–10):292-304. doi:10.1038/s41417-018-0050-1
  • Huang WC, Kuo KT, Adebayo BO, et al. Garcinol inhibits cancer stem cell-like phenotype via suppression of the Wnt/beta-catenin/STAT3 axis signalling pathway in human non-small cell lung carcinomas. J Nutr Biochem. 2018;54:140–150.

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