Long noncoding RNA MEG3 suppresses cell proliferation, migration and invasion, induces apoptosis and paclitaxel-resistance via miR-4513/PBLD axis in breast cancer cells

References

• DeSantis C, Ma J, Bryan L, et al. Breast cancer statistics, 2013. CA Cancer J Clin. 2014;64:1.
   PubMed Web of Science ®Google Scholar
• O’Sullivan CC, Loprinzi CL, Haddad TC. Updates in the evaluation and management of breast cancer. Mayo Clin Proc. 2018;93:6.
   Web of Science ®Google Scholar
• Gonzalez-Angulo AM, Morales-Vasquez F, Hortobagyi GN. Overview of resistance to systemic therapy in patients with breast cancer. Adv Exp Med Biol. 2007;608:1–22.
   PubMed Web of Science ®Google Scholar
• Hu G, Chong RA, Yang Q, et al. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell. 2009;15:1.
   PubMed Web of Science ®Google Scholar
• Paridaens R, Biganzoli L, Bruning P, et al. Paclitaxel versus doxorubicin as first-line single-agent chemotherapy for metastatic breast cancer: a European organization for research and treatment of cancer randomized study with cross-over. J Clin Oncol. 2000;18:4.
   PubMed Web of Science ®Google Scholar
• Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Mol Cell. 2011;43:6.
   Web of Science ®Google Scholar
• Yang L, Froberg JE, Lee JT. Long noncoding RNAs: fresh perspectives into the RNA world. Trends Biochem Sci. 2014;39:1.
   PubMed Web of Science ®Google Scholar
• Huarte M. The emerging role of lncRNAs in cancer. Nat Med. 2015;21:11.
   PubMed Web of Science ®Google Scholar
• Schmitt AM, Chang HY. Long Noncoding RNAs in Cancer Pathways. Cancer Cell. 2016;29:4.
   Web of Science ®Google Scholar
• Kruer TL, Dougherty SM, Reynolds L, et al. Expression of the lncRNA maternally expressed gene 3 (MEG3) Contributes to the control of lung cancer cell proliferation by the Rb pathway. PLoS One. 2016;11:11.
   Web of Science ®Google Scholar
• Zhang J, Yao T, Wang Y, et al. Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21. Cancer Biol Ther. 2016;17:1.
   PubMed Web of Science ®Google Scholar
• Zhang JJ, Guo SH, Jia BQ. Down-regulation of long non-coding RNA MEG3 serves as an unfavorable risk factor for survival of patients with breast cancer. Eur Rev Med Pharmacol Sci. 2016;20:24.
   Web of Science ®Google Scholar
• Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet. 2010;11:9.
   PubMed Web of Science ®Google Scholar
• Melo SA, Esteller M. Disruption of microRNA nuclear transport in human cancer. Semin Cancer Biol. 2014;27. DOI:10.1016/j.semcancer.2014.02.012
   PubMed Web of Science ®Google Scholar
• Shin VY, Chu KM. MiRNA as potential biomarkers and therapeutic targets for gastric cancer. World J Gastroenterol. 2014;20:30.
   Web of Science ®Google Scholar
• Jiang G, Shi W, Fang H, et al. miR27a promotes human breast cancer cell migration by inducing EMT in a FBXW7dependent manner. Mol Med Rep. 2018;18:6.
   Web of Science ®Google Scholar
• Tian Y, Fu X, Li Q, et al. MicroRNA181 serves an oncogenic role in breast cancer via the inhibition of SPRY4. Mol Med Rep. 2018;18:6.
   Web of Science ®Google Scholar
• Ghanbari M, de Vries PS, de Looper H, et al. A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease. Hum Mutat. 2014;35:12.
   Web of Science ®Google Scholar
• Ghanbari M, Erkeland SJ, Xu L, et al. Genetic variants in microRNAs and their binding sites within gene 3©UTRs associate with susceptibility to age-related macular degeneration. Hum Mutat. 2017;38:7.
   PubMed Web of Science ®Google Scholar
• Zhang N, Li Y, Zheng Y, et al. miR-608 and miR-4513 significantly contribute to the prognosis of lung adenocarcinoma treated with EGFR-TKIs. Lab Invest. 2019;99:4.
   PubMed Web of Science ®Google Scholar
• Li Y, Zhu H, Wang J, et al. miR-4513 promotes breast cancer progression through targeting TRIM3. Am J Transl Res. 2019;11:4.
   Web of Science ®Google Scholar
• Li DM, Zhang J, Li WM, et al. MAWBP and MAWD inhibit proliferation and invasion in gastric cancer. World J Gastroenterol. 2013;19:18.
   Web of Science ®Google Scholar
• Zhang Y, Wu J, Jing H, et al. Long noncoding RNA MEG3 inhibits breast cancer growth via upregulating endoplasmic reticulum stress and activating NF-kappaB and p53. Cell Biochem. 2019;120:4
   Web of Science ®Google Scholar
• Paraskevopoulou MD, Vlachos IS, Karagkouni D, et al. DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. Nucleic Acids Res. 2016;44(D1):D231–238. .
   PubMed Web of Science ®Google Scholar
• Khaitan D, Dinger ME, Mazar J, et al. The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Res. 2011;71:11.
   Web of Science ®Google Scholar
• Fatica A, Bozzoni I. Long non-coding RNAs: new players in cell differentiation and development. Nat Rev Genet. 2014;15:1.
   PubMed Web of Science ®Google Scholar
• Yang X, Song JH, Cheng Y, et al. Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells. Gut. 2014;63:6.
   Web of Science ®Google Scholar
• Zhang Y, Zhu M, Sun Y, et al. Upregulation of lncRNA CASC2 Suppresses Cell Proliferation and Metastasis of Breast Cancer via Inactivation of the TGF-beta Signaling Pathway. Oncol Res. 2019;27:3.
   Web of Science ®Google Scholar
• Tripathi V, Shen Z, Chakraborty A, et al. Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet. 2013;9:3.
   Web of Science ®Google Scholar
• Zhang A, Zhao JC, Kim J, et al. LncRNA HOTAIR enhances the androgen-receptor-mediated transcriptional program and drives castration-resistant prostate cancer. Cell Rep. 2015;13:1.
   PubMed Web of Science ®Google Scholar
• Lu KH, Li W, Liu XH, et al. Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression. BMC Cancer. 2013;13. DOI:10.1186/1471-2407-13-461.
   Web of Science ®Google Scholar
• Wang P, Ren Z, Sun P. Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation. J Cell Biochem. 2012;113:6.
   Web of Science ®Google Scholar
• Zhang Y, Liu J, Lv Y, et al. LncRNA meg3 suppresses hepatocellular carcinoma in vitro and vivo studies. Am J Transl Res. 2019;11:7.
   Web of Science ®Google Scholar
• Wang W, Xie Y, Chen F, et al. LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer. World J Gastroenterol. 2019;25:29.
   Web of Science ®Google Scholar
• Akiyama M, Sowa Y, Taniguchi T, et al. Three combined treatments, a novel HDAC inhibitor OBP-801/YM753, 5-fluorouracil, and paclitaxel, induce G(2) phase arrest through the p38 pathway in human ovarian cancer cells. Oncol Res. 2017;25:8.
   Web of Science ®Google Scholar
• Wang H, Li H, Zhang L, et al. Overexpression of MEG3 sensitizes colorectal cancer cells to oxaliplatin through regulation of miR-141/PDCD4 axis. Biomed Pharmacother. 2018;106. DOI:10.1016/j.biopha.2018.07.131.
   Web of Science ®Google Scholar
• Zhang S, Leng T, Zhang Q, et al. Sanguinarine inhibits epithelial ovarian cancer development via regulating long non-coding RNA CASC2-EIF4A3 axis and/or inhibiting NF-kappaB signaling or PI3K/AKT/mTOR pathway. Biomed Pharmacother. 2018;102:302–308
   PubMed Web of Science ®Google Scholar
• Ding H, Shi Y, Liu X, et al. miR-4513 promotes gastric cancer cell proliferation and epithelial-mesenchymal transition through targeting KAT6B. Hum Gene Ther Clin Dev. 2019. DOI:10.1089/humc.2019.094.
   PubMed Web of Science ®Google Scholar
• Xu YX, Sun J, Xiao WL, et al. MiR-4513 mediates the proliferation and apoptosis of oral squamous cell carcinoma cells via targeting CXCL17. Eur Rev Med Pharmacol Sci. 2019;23:9.
   Google Scholar
• Neo SY, Leow CK, Vega VB, et al. Identification of discriminators of hepatoma by gene expression profiling using a minimal dataset approach. Hepatology. 2004;39:4.
   Web of Science ®Google Scholar
• Long J, Lang ZW, Wang HG, et al. Glutamine synthetase as an early marker for hepatocellular carcinoma based on proteomic analysis of resected small hepatocellular carcinomas. Hepatobiliary Pancreat Dis Int. 2010;9:3.
   Web of Science ®Google Scholar
• Liang Y, Song X, Li Y, et al. circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer. Oncogene. 2019. DOI:10.1038/s41388-019-0926-z.
   Web of Science ®Google Scholar