628
Views
1
CrossRef citations to date
0
Altmetric
Research Paper

MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-κB signaling in gouty arthritis

, , ORCID Icon, &
Pages 805-819 | Received 11 Oct 2021, Accepted 14 Jan 2022, Published online: 03 Mar 2022

References

  • He M, Hu C, and Chen M, et al. Effects of gentiopicroside on activation of NLRP3 inflammasome in acute gouty arthritis mice induced by MSU. J Nat Med. 2022;76(1):178–187 .
  • Patil T, Soni A, Acharya S. A brief review on in vivo models for gouty arthritis. Metabol Open. 2021 Sep;11:100100.
  • Singh JA, Gaffo A. Gout epidemiology and comorbidities. Semin Arthritis Rheum. 2020 Jun;50(3s):S11–s16.
  • Senthelal S, Li J, Goyal A, et al. Arthritis. Treasure Island (FL): StatPearls Publishing. 2021. StatPearls. Copyright © 2021, StatPearls Publishing LLC.
  • Hsu DZ, Chen SJ, Chu PY, et al. Therapeutic effects of sesame oil on monosodium urate crystal-induced acute inflammatory response in rats. Springerplus. 2013;2:659.
  • Pascual E, Pedraz T. Gout. Curr Opin Rheumatol. 2004 May;16(3):282–286.
  • Jeong JH, Hong S, Kwon OC, et al. CD14(+) cells with the phenotype of infiltrated monocytes consist of distinct populations characterized by anti-inflammatory as well as pro-inflammatory activity in gouty arthritis. Front Immunol. 2017;8:1260.
  • Martinon F, Pétrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006 Mar 9;440(7081):237–241.
  • Ghosh P, Cho M, Rawat G, et al. Treatment of acute gouty arthritis in complex hospitalized patients with anakinra. Arthritis Care Res (Hoboken). 2013 Aug;65(8):1381–1384.
  • Yang J, Wu M, Fang H, et al. Puerarin prevents acute liver injury via inhibiting inflammatory responses and ZEB2 expression. Front Pharmacol. 2021;12:727916.
  • Mead B, Tomarev S. The role of miRNA in retinal ganglion cell health and disease. Neural Regen Res. 2022 Mar;17(3):516–522.
  • Ma T, Liu X, Cen Z, et al. MicroRNA-302b negatively regulates IL-1β production in response to MSU crystals by targeting IRAK4 and EphA2. Arthritis Res Ther. 2018 Feb 26;20(1):34.
  • Wang X, Chi J, Dong B, et al. MiR-223-3p and miR-22-3p inhibit monosodium urate-induced gouty inflammation by targeting NLRP3. Int J Rheum Dis. 2021 Apr;24(4):599–607.
  • Jin HM, Kim TJ, Choi JH, et al. MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis. Arthritis Res Ther. 2014 Apr 7;16(2):R88.
  • Mandolesi G, De Vito F, Musella A, et al. miR-142-3p is a key regulator of IL-1β-dependent synaptopathy in neuroinflammation. J Neurosci. 2017 Jan 18;37(3):546–561.
  • Qing X, Zhang Y, Peng Y, et al. Mir-142-3p regulates inflammatory response by contributing to increased TNF-α in chronic rhinosinusitis with nasal polyposis. Ear Nose Throat J. 2021 Jan;100(1): Np50–np56.
  • Zhu L, Shi Y, Liu L, et al. Mesenchymal stem cells-derived exosomes ameliorate nucleus pulposus cells apoptosis via delivering miR-142-3p: therapeutic potential for intervertebral disc degenerative diseases. Cell Cycle. 2020 Jul;19(14):1727–1739.
  • Meng D, Li J, Li H, et al. Salvianolic acid B remits LPS-induced injury by up-regulating miR-142-3p in MH7A cells. Biomed Pharmacother. 2019;115:108876.
  • Bohatá J, Horváthová V, Pavlíková M, et al. Circulating microRNA alternations in primary hyperuricemia and gout. Arthritis Res Ther. 2021 Jul 10;23(1):186.
  • Meng Q, Meng W, Bian H, et al. Total glucosides of paeony protects THP-1 macrophages against monosodium urate-induced inflammation via MALAT1/miR-876-5p/NLRP3 signaling cascade in gouty arthritis. Biomed Pharmacother. 2021;138:111413.
  • Erster O, Mendelson E, and Levy V, et al. Rapid and high-throughput reverse transcriptase quantitative PCR (RT-qPCR) assay for identification and differentiation between SARS-CoV-2 variants B.1.1.7 and B.1.351. Microbiol Spectr. 2021;9((2): ;e0050621.
  • Mishra M, Tiwari S, Gunaseelan A, et al. Improving the sensitivity of traditional Western blotting via streptavidin containing poly-horseradish peroxidase (PolyHRP). Electrophoresis. 2019 Jul;40(12–13):1731–1739.
  • Brzuzan P, Mazur-Marzec H, Florczyk M, et al. Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: screening cyanopeptolins produced by Nostoc from the Baltic Sea. Toxicol In Vitro. 2020;68:104951.
  • Hoesel B, Schmid JA. The complexity of NF-κB signaling in inflammation and cancer. Mol Cancer. 2013 Aug 2;12:86.
  • Chen H, Zhou GX, He XJ, et al. Efficacy of fire needle on acute gouty arthritis induced by monosodium urate in rat. J Tradit Chin Med. 2021 Aug;41(4):564–570.
  • Wang Y, Zhu W, Lu D, et al. Tetrahydropalmatine attenuates MSU crystal-induced gouty arthritis by inhibiting ROS-mediated NLRP3 inflammasome activation. Int Immunopharmacol. 2021 Sep 3;100:108107.
  • Li G, Zhang H, Ma H, et al. MiR-221-5p is involved in the regulation of inflammatory responses in acute gouty arthritis by targeting IL-1β. Int J Rheum Dis. 2021 Mar;24(3):335–340.
  • Chen X, Gao Q, Zhou L, et al. MiR-146a alleviates inflammation of acute gouty arthritis rats through TLR4/MyD88 signal transduction pathway. Eur Rev Med Pharmacol Sci. 2019 Nov;23(21):9230–9237.
  • Zhou W, Wang Y, Wu R, et al. MicroRNA-488 and −920 regulate the production of proinflammatory cytokines in acute gouty arthritis. Arthritis Res Ther. 2017 Sep 15;19(1):203.
  • Gao Y, Zhao H, Li Y. LncRNA MCM3AP-AS1 regulates miR-142-3p/HMGB1 to promote LPS-induced chondrocyte apoptosis. BMC Musculoskelet Disord. 2019 Dec 13;20(1):605.
  • Renman E, Brink M, and Ärlestig L, et al. Dysregulated microRNA expression in rheumatoid arthritis families-a comparison between rheumatoid arthritis patients, their first-degree relatives, and healthy controls. Clin Rheumatol. 2021 Jun ;40(6 2387–2394).
  • Hu HY, Wang JQ. [MiR-142-3p inhibitslipopolysaccharide-induced inflammatory response in human periodontal ligament cells through targeting IRAK1]. Shanghai Kou Qiang Yi Xue. 2016 Dec;25(6):682–687.
  • Su Q, Lv X, Ye Z, et al. The mechanism of miR-142-3p in coronary microembolization-induced myocardiac injury via regulating target gene IRAK-1. Cell Death Dis. 2019 Jan 25;10(2):61.
  • Zhang D, Wang Y, Xia Y, et al. Repression of miR-142-3p alleviates psoriasis-like inflammation by repressing proliferation and promoting apoptosis of keratinocytes via targeting Sema3A. Mol Cell Probes. 2020;52:101573.
  • Wang Y, Liang J, Qin H, et al. Elevated expression of miR-142-3p is related to the pro-inflammatory function of monocyte-derived dendritic cells in SLE. Arthritis Res Ther. 2016 Nov 16;18(1):263.
  • Verschueren K, Remacle JE, Collart C, et al. SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5’-CACCT sequences in candidate target genes. J Biol Chem. 1999 Jul 16;274(29):20489–20498.
  • Rasouly HM, Kumar S, Chan S, et al. Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Kidney Int. 2016 Dec;90(6):1262–1273.
  • Ding Q, Wang Y, Zhang AL, et al. ZEB2 attenuates LPS-induced inflammation by the NF-κB pathway in HK-2 cells. Inflammation. 2018 Mar;41(2):722–731.
  • Yang J, Xu L, Wu M, et al. Paeonol derivative-6 attenuates inflammation by activating ZEB2 in acute liver injury. Int Immunopharmacol. 2021;91:107235.
  • Shen Z, Xuan W, Wang H, et al. miR-200b regulates cellular senescence and inflammatory responses by targeting ZEB2 in pulmonary emphysema. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):656–663.
  • Ghosh S, and Karin M. Missing pieces in the NF-kappaB puzzle. Cell. 2002 Apr;109 Suppl: S81–S96 .
  • Chen B, Li H, Ou G, et al. Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage. Arthritis Res Ther. 2019 Aug 27;21(1):193.
  • Wang Z, Zhao Y, Phipps-Green A, et al. Differential DNA methylation of networked signaling, transcriptional, innate and adaptive immunity, and osteoclastogenesis genes and pathways in gout. Arthritis Rheumatol. 2020 May;72(5):802–814.
  • Huang Q, Gao W, Mu H, et al. HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF-κB-MyD88 signaling pathway and disrupting mitochondrial function. Oxid Med Cell Longev. 2020;2020:8706898.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.