MiR-4268 suppresses gastric cancer genesis through inhibiting keratin 80

References

• Rawla P, Barsouk A. Epidemiology of gastric cancer: global trends, risk factors and prevention. Prz Gastroenterol. 2019;14(1):26–38.
   PubMed Web of Science ®Google Scholar
• Kwon HN, Lee H, Park JW, et al. Screening for early gastric cancer using a noninvasive urine metabolomics approach. Cancers (Basel). 2020;12(10):2904.
   Web of Science ®Google Scholar
• Fitzmaurice C, Allen C, Barber RM, et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncol. 2017;3(4):524–548.
   PubMed Web of Science ®Google Scholar
• Chen Z, Gao Y, Gao S, et al. MiR-135b-5p promotes viability, proliferation, migration and invasion of gastric cancer cells by targeting krüppel-like factor 4 (KLF4). Arch Med Sci. 2020;16(1):167–176.
   PubMed Web of Science ®Google Scholar
• Cao C, Sun D, Zhang L, et al. miR-186 affects the proliferation, invasion and migration of human gastric cancer by inhibition of twist1. Oncotarget. 2016;7(48):79956–79963.
   PubMedGoogle Scholar
• Fernández-Hernando C, Suárez Y, Rayner KJ, et al. MicroRNAs in lipid metabolism. Curr Opin Lipidol. 2011;22(2):86–92.
   PubMed Web of Science ®Google Scholar
• Najafi-Shoushtari SH. MicroRNAs in cardiometabolic disease. Curr Atheroscler Rep. 2011;13(3):202–207.
   PubMed Web of Science ®Google Scholar
• Lee YS, Dutta A. MicroRNAs in cancer. Annu Rev Pathol. 2009;4(1):199–227.
   PubMed Web of Science ®Google Scholar
• Li H, Yao G, Zhai J, et al. LncRNA FTX promotes proliferation and invasion of gastric cancer via miR-144/ZFX axis. Onco Targets Ther. 2019;12:11701–11713.
   PubMedGoogle Scholar
• Cao Y, Xiong JB, Zhang GY, et al. Long noncoding RNA UCA1 regulates PRL-3 expression by sponging MicroRNA-495 to promote the progression of gastric cancer. Mol Ther Nucleic Acids. 2020;19:853–864.
   PubMedGoogle Scholar
• Wang S, Yuan Q, Zhao W, et al. Circular RNA RBM33 contributes to extracellular matrix degradation via miR-4268/EPHB2 axis in abdominal aortic aneurysm. PeerJ. 2021;9:e12232.
   PubMed Web of Science ®Google Scholar
• Zhao L, Xue M, Zhang L, et al. MicroRNA-4268 inhibits cell proliferation via AKT/JNK signalling pathways by targeting Rab6B in human gastric cancer. Cancer Gene Ther. 2020;27(6):461–472.
   PubMed Web of Science ®Google Scholar
• Santos-Faria J, Gavina C, Rodrigues P, et al. MicroRNAs and ventricular remodeling in aortic stenosis. Rev port cardiol. 2020;39(7):377–387.
   PubMedGoogle Scholar
• Santos-Faria J, Gavina C, Rodrigues P, et al. MicroRNAs and ventricular remodeling in aortic stenosis. Rev port cardiol: orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese j cardiol: off j Portuguese Soc Cardiol. 2020;39(7):377–387.
   Google Scholar
• Luo M, Ding L, Li Q, et al. miR-668 enhances the radioresistance of human breast cancer cell by targeting IκBα. Breast Cancer (Tokyo, Japan). 2017;24(5):673–682.
   PubMed Web of Science ®Google Scholar
• Lin J, Fan X, Chen J, et al. Small interfering RNA-mediated knockdown of KRT80 suppresses colorectal cancer proliferation. Exp Ther Med. 2020;20(6):176.
   PubMed Web of Science ®Google Scholar
• Toivola DM, Boor P, Alam C, et al. Keratins in health and disease. Curr Opin Cell Biol. 2015;32:73–81.
   PubMed Web of Science ®Google Scholar
• Omary MB, Ku NO, Strnad P, et al. Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest. 2009;119(7):1794–1805.
   PubMed Web of Science ®Google Scholar
• Liu O, Wang C, Wang S, et al. Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer. J Cancer. 2021;12(22):6835–6850.
   PubMed Web of Science ®Google Scholar
• Perone Y, Farrugia AJ, Rodríguez-Meira A, et al. SREBP1 drives keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer. Nat Commun. 2019;10(1):2115.
   PubMedGoogle Scholar
• Song H, Xu Y, Xu T, et al. CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p. Biomed Pharmacother. 2020;126:109941.
   PubMed Web of Science ®Google Scholar
• Fang J, Wang H, Liu Y, et al. High KRT8 expression promotes tumor progression and metastasis of gastric cancer. Cancer Sci. 2017;108(2):178–186.
   PubMed Web of Science ®Google Scholar
• Wang PB, Chen Y, Ding GR, et al. Keratin 18 induces proliferation, migration, and invasion in gastric cancer via the MAPK signalling pathway. Clin Exp Pharmacol Physiol. 2020;48(1):147–156.
   Web of Science ®Google Scholar
• Pai SI, Lin YY, Macaes B, et al. Prospects of RNA interference therapy for cancer. Gene Ther. 2006;13(6):464–477.
   PubMed Web of Science ®Google Scholar
• Ahadi A. A systematic review of microRNAs as potential biomarkers for diagnosis and prognosis of gastric cancer. Immunogenetics. 2021;73(2):155–161.
   PubMed Web of Science ®Google Scholar
• Ouyang J, Xie Z, Lei X, et al. Clinical crosstalk between microRNAs and gastric cancer (review). Int J Oncol. 2021;58(4). DOI:10.3892/ijo.2021.5187.
   Web of Science ®Google Scholar
• Wang H, Sun G, Xu P, et al. Circular RNA TMEM87A promotes cell proliferation and metastasis of gastric cancer by elevating ULK1 via sponging miR-142-5p. J Gastroenterol. 2020;56(2):125–138.
   PubMed Web of Science ®Google Scholar
• Li J, Ye D, Shen P, et al. Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway. J Exp Clin Cancer Res. 2020;39(1):212.
   PubMed Web of Science ®Google Scholar
• Bertoli G, Cava C, Castiglioni I. MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer. Theranostics. 2015;5(10):1122–1143.
   PubMed Web of Science ®Google Scholar