Upregulation of miR-151-5p promotes the apoptosis of intestinal epithelial cells by targeting brain-derived neurotrophic factor in ulcerative colitis mice

References

• Soroosh A, Rankin CR, Polytarchou C, et al. miR-24 is elevated in ulcerative colitis patients and regulates intestinal epithelial barrier function. Am J Pathol. 2019;189:1763–1774.
   PubMed Web of Science ®Google Scholar
• Wang JP, Dong LN, Wang M, et al. MiR-146a regulates the development of ulcerative colitis via mediating the TLR4/MyD88/NF-κB signaling pathway. Eur Rev Med Pharmacol Sci. 2019;23:2151–2157.
   PubMed Web of Science ®Google Scholar
• Lu X, Yu Y, Tan S. The role of the miR-21-5p-mediated inflammatory pathway in ulcerative colitis. Exp Ther Med. 2020;19:981–989.
   PubMed Web of Science ®Google Scholar
• Gillen CD, Walmsley RS, Prior P, et al. Ulcerative colitis and Crohn’s disease: a comparison of the colorectal cancer risk in extensive colitis. Gut. 1994;35:1590–1592.
   PubMed Web of Science ®Google Scholar
• Coskun M, Bjerrum JT, Seidelin JB, et al. miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis. World J Gastroenterol. 2013;19:4289–4299.
   PubMed Web of Science ®Google Scholar
• Modak JM, Roy-O’Reilly M, Zhu L, et al. Differential microribonucleic acid expression in cardioembolic stroke. J Stroke Cerebrovasc Dis. 2019;28:121–124.
   PubMed Web of Science ®Google Scholar
• Qu S, Shen Y, Wang M, et al. Suppression of miR-21 and miR-155 of macrophage by cinnamaldehyde ameliorates ulcerative colitis. Int Immunopharmacol. 2019;67:22–34.
   PubMed Web of Science ®Google Scholar
• Liu C, Li W, Zhang L, et al. Tumor-suppressor microRNA-151-5p regulates the growth, migration and invasion of human breast cancer cells by inhibiting SCOS5. Am J Transl Res. 2019;11:7376–7384.
   PubMed Web of Science ®Google Scholar
• Hsu KW, Fang WL, Huang KH, et al. Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression. Oncotarget. 2016;7:38036–38051.
   PubMedGoogle Scholar
• Ding J, Huang S, Wu S, et al. Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA. Nat Cell Biol. 2010;12(4):390–399.
   PubMed Web of Science ®Google Scholar
• Chiyomaru T, Yamamura S, Zaman MS, et al. Genistein suppresses prostate cancer growth through inhibition of oncogenic microRNA-151. PLoS One. 2012;7(8):e43812.
   PubMed Web of Science ®Google Scholar
• Chen C, Wang D, Moshaverinia A, et al. Mesenchymal stem cell transplantation in tight-skin mice identifies miR-151-5p as a therapeutic target for systemic sclerosis. Cell Res. 2017;27(4):559–577.
   PubMed Web of Science ®Google Scholar
• Yi LI, Liu Y, Wang XP, et al. Preliminary study on microRNA differential expression in patients with peripheral blood of ulcerative colitis and its relation to biaoben-xushi syndrome. Guiding J Traditional Chinese Med Pharm. 2017;23(06):19–21.
   Google Scholar
• Paraskevi A, Theodoropoulos G, Papaconstantinou I, et al. Circulating MicroRNA in inflammatory bowel disease. J Crohns Colitis. 2012;6(9):900–904.
   PubMed Web of Science ®Google Scholar
• Fisher K. MicroRNA in inflammatory bowel disease: translational research and clinical implication. World J Gastroenterol. 2015;21(43):12274–12282.
   PubMed Web of Science ®Google Scholar
• Han K, Jia N, Li J, et al. Chronic caffeine treatment reverses memory impairment and the expression of brain BNDF and TrkB in the PS1/APP double transgenic mouse model of Alzheimer’s disease. Mol Med Rep. 2013;8:737–740.
   PubMed Web of Science ®Google Scholar
• Steinkamp M, Schulte N, Spaniol U, et al. Brain derived neurotrophic factor inhibits apoptosis in enteric glia during gut inflammation. Med Sci Monit. 2012;18:Br117–Br122.
   PubMed Web of Science ®Google Scholar
• Zhao DY, Zhang WX, Qi QQ, et al. Brain-derived neurotrophic factor modulates intestinal barrier by inhibiting intestinal epithelial cells apoptosis in mice. Physiol Res. 2018;67:475–485.
   PubMed Web of Science ®Google Scholar
• Di Sabatino A, Ciccocioppo R, Luinetti O, et al. Increased enterocyte apoptosis in inflamed areas of Crohn’s disease. Dis Colon Rectum. 2003;46:1498–1507.
   PubMed Web of Science ®Google Scholar
• Gitter AH, Wullstein F, Fromm M, et al. Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology. 2001;121:1320–1328.
   PubMed Web of Science ®Google Scholar
• Li M, Zhang S, Qiu Y, et al. Upregulation of miR-665 promotes apoptosis and colitis in inflammatory bowel disease by repressing the endoplasmic reticulum stress components XBP1 and ORMDL3. Cell Death Dis. 2017;8:e2699.
   PubMed Web of Science ®Google Scholar
• Bing X, Xuelei L, Wanwei D, et al. EGCG maintains Th1/Th2 balance and mitigates ulcerative colitis induced by dextran sulfate sodium through TLR4/MyD88/NF-κB signaling pathway in rats. Can J Gastroenterol Hepatol. 2017;2017:3057268.
   PubMed Web of Science ®Google Scholar
• Shkoda A, Ruiz PA, Daniel H, et al. Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation. Gastroenterology. 2007;132:190–207.
   PubMed Web of Science ®Google Scholar
• Liu S, Zhang S, Lv X, et al. Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway. Int Immunopharmacol. 2019;75:105768.
   PubMed Web of Science ®Google Scholar
• Chen Q, Fang X, Yao N, et al. Suppression of miR-330-3p alleviates DSS-induced ulcerative colitis and apoptosis by upregulating the endoplasmic reticulum stress components XBP1. Hereditas. 2020;157:18.
   PubMed Web of Science ®Google Scholar
• Xu X, Zhu X, Wang C, et al. microRNA-650 promotes inflammation induced apoptosis of intestinal epithelioid cells by targeting NLRP6. Biochem Biophys Res Commun. 2019;517:551–556.
   PubMed Web of Science ®Google Scholar
• Jiang W, Han YP, Hu M, et al. A study on regulatory mechanism of miR-223 in ulcerative colitis through PI3K/Akt-mTOR signaling pathway. Eur Rev Med Pharmacol Sci. 2019;23:4865–4872.
   PubMed Web of Science ®Google Scholar
• Chu XQ, Wang J, Chen GX, et al. Overexpression of microRNA-495 improves the intestinal mucosal barrier function by targeting STAT3 via inhibition of the JAK/STAT3 signaling pathway in a mouse model of ulcerative colitis. Pathol Res Pract. 2018;214:151–162.
   PubMed Web of Science ®Google Scholar
• Zhang SQ, Ni WK, Xiao MB, et al. Actin related protein 3 (ARP3) promotes apoptosis of intestinal epithelial cells in ulcerative colitis. Pathol Res Pract. 2019;215:235–242.
   PubMed Web of Science ®Google Scholar
• Koch S, Nusrat A. The life and death of epithelia during inflammation: lessons learned from the gut. Annu Rev Pathol. 2012;7:35–60.
   PubMed Web of Science ®Google Scholar
• Earnshaw WC, Martins LM, Kaufmann SH. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem. 1999;68:383–424.
   PubMed Web of Science ®Google Scholar
• Amasheh S, Meiri N, Gitter AH. Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J Cell Sci. 2002;115:4969–4976.
   PubMed Web of Science ®Google Scholar
• Zhang YG, Wu S, Xia Y, et al. Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells. PLoS One. 2013;8:e58606.
   PubMed Web of Science ®Google Scholar