References
- Tell G, Quadrifoglio F, Tiribelli C, et al. The many functions of APE1/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal. 2009;11:601–620.
- Vascotto C, Fantini D, Romanello M, et al. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol. 2009;29:1834–1854.
- Abbotts R, Madhusudan S. Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer. Cancer Treat Rev. 2010;36:425–435.
- Li L, Li N, Fu S, et al. Base excision repair-inspired DNA motor powered by intracellular apurinic/apyrimidinic endonuclease. Nanoscale. 2019;11:1343–1350.
- Yu Y, Li L, Li G, et al. Intracellular enzyme-powered DNA circuit with a tunable amplifier for miRNA imaging. Chem Commun (Camb). 2021;57:3753–3756.
- Zhou T, Luo R, Li Y, et al. Activity assay and intracellular imaging of APE1 assisted with tetrahedral DNA nanostructure modified-dnazyme and molecular beacon. Sens Actuators B Chem. 2020;317:128203.
- Zhang Y, Deng Y, Wang C, et al. Probing and regulating the activity of cellular enzymes by using DNA tetrahedron nanostructures. Chem Sci. 2019;10:5959–5966.
- Tang S, Davoudi Z, Wang G, et al. Soft materials as biological and artificial membranes. Chem Soc Rev. 2021;50(22):12679–12701.
- Zheng C, Li M, Ding J. Challenges and opportunities of nanomedicines in clinical translation. BIO Integration. 2021;2(2):57–60.
- Hua C, Zhang Y, Liu Y. Enhanced anticancer efficacy of chemotherapy by amphiphilic Y-shaped polypeptide micelles. Front Bioeng Biotechnol. 2021;9. DOI:10.3389/fbioe.2021.817143
- Liao J, Peng H, Wei X, et al. A bio-responsive 6-mercaptopurine/doxorubicin based “Click Chemistry” polymeric prodrug for cancer therapy. Mater Sci Eng C. 2020;108:110461.
- Shi L, Zhang J, Zhao M, et al. Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery. Nanoscale. 2021;13:10748–10764.
- Wei L, Chen J, Ding J. Sequentially stimuli-responsive anticancer nanomedicines. Nanomedicine. 2021;16:261–264.
- Liao J, Peng H, Liu C, et al. Dual pH-responsive-charge-reversal micelle platform for enhanced anticancer therapy. Mater Sci Eng C. 2021;118:111527.
- Hu R, Zheng H, Cao J, et al. Synthesis and in vitro characterization of carboxymethyl chitosan-CBA-doxorubicin conjugate nanoparticles as ph-sensitive drug delivery systems. J Biomed Nanotechnol. 2017;13:1097–1105.
- Wang J, Xu W, Zhang N, et al. X-ray-responsive polypeptide nanogel for concurrent chemoradiotherapy. J Control Release. 2021;332:1–9.
- Ma W, Chen Q, Xu W, et al. Self-targeting visualizable hyaluronate nanogel for synchronized intracellular release of doxorubicin and cisplatin in combating multidrug-resistant breast cancer. Nano Res. 2021;14:846–857.
- Feng X, Xu W, Xu X, et al. Cystine proportion regulates fate of polypeptide nanogel as nanocarrier for chemotherapeutics. Sci China Chem. 2021;64:293–301.
- Jiang Q, Shi Y, Zhang Q, et al. A self-assembled DNA origami-gold nanorod complex for cancer theranostics. Small. 2015;11:5134–5141.
- Fakhoury JJ, McLaughlin CK, Edwardson TW, et al. Development and characterization of gene silencing DNA cages. Biomacromolecules. 2014;15:276–282.
- Tay CY, Yuan L, Leong DT. Nature-inspired DNA nanosensor for real-time in situ detection of mRNA in living cells. ACS Nano. 2015;9:5609–5617.
- Xie N, Liu S, Yang X, et al. DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery. Analyst. 2017;142:3322–3332.
- Meng HM, Liu H, Kuai H, et al. Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy. Chem Soc Rev. 2016;45:2583–2602.
- Liu Y, Chen Q, Liu J, et al. Design of a modular DNA triangular-prism sensor enabling ratiometric and multiplexed biomolecule detection on a single microbead. Anal Chem. 2017;89:3590–3596.
- Zheng X, Peng R, Jiang X, et al. Fluorescence resonance energy transfer-based DNA nanoprism with a split aptamer for adenosine triphosphate sensing in living cells. Anal Chem. 2017;89:10941–10947.
- Zhou L, Liu Y, Shi H, et al. Flexible assembly of an enzyme cascade on a DNA triangle prism nanostructure for the controlled biomimetic generation of nitric oxide. Chembiochem. 2018;19:2099–2106.
- Liu Q, Wang D, Xu Z, et al. Targeted delivery of Rab26 siRNA with precisely tailored DNA prism for lung cancer therapy. Chembiochem. 2019;20:1139–1144.
- Wu D, Li BL, Zhao Q, et al. Assembling defined DNA nanostructure with nitrogen-enriched carbon dots for theranostic cancer applications. Small. 2020;16:e1906975.
- Wang D, Xiang DB, Yang XQ, et al. APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells. Lung Cancer. 2009;66:298–304.
- Al-Attar A, Gossage L, Fareed KR, et al. Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers. Br J Cancer. 2010;102:704–709.
- Keum JW, Bermudez H. Enhanced resistance of DNA nanostructures to enzymatic digestion. Chem Comm. 2009;7036–7038. DOI:10.1039/b917661f
- Li N, Wang M, Gao X, et al. A DNA tetrahedron nanoprobe with controlled distance of dyes for multiple detection in living cells and in vivo. Anal Chem. 2017;89:6670–6677.
- Karukstis KK, Thompson EH, Whiles JA, et al. Deciphering the fluorescence signature of daunomycin and doxorubicin. Biophys Chem. 1998;73:249–263.
- Mohan P, Rapoport N. Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery and nuclear trafficking. Mol Pharm. 2010;7:1959–1973.
- Liang L, Li J, Li Q, et al. Single-particle tracking and modulation of cell entry pathways of a tetrahedral DNA nanostructure in live cells. Angew Chem. 2014;53:7745–7750.
- Fortini P, Pascucci B, Parlanti E, et al. The base excision repair: mechanisms and its relevance for cancer susceptibility. Biochimie. 2003;85:1053–1071.
- Poletto M, Di Loreto C, Marasco D, et al. Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers. Biochem Biophys Res Commun. 2012;424:34–39.