CircMAP3K4 protects human lens epithelial cells from H₂O₂-induced dysfunction by targeting miR-193a-3p/PLCD3 axis in age-related cataract

References

• Congdon NG, Friedman DS, Lietman T. Important causes of visual impairment in the world today. JAMA. 2003;290(15):2057–2060. Epub 2003/10/16 PubMed PMID: 14559961. DOI:10.1001/jama.290.15.2057.
   PubMed Web of Science ®Google Scholar
• Asbell PA, Dualan I, Mindel J, et al. Age-related cataract. Lancet. 2005;365(9459):599–609. Epub 2005/02/15 PubMed PMID: 15708105. DOI:10.1016/s0140-6736(05)17911-2.
   PubMed Web of Science ®Google Scholar
• Watkinson S, Seewoodhary R. Cataract management: effect on patients’ quality of life. Nursing standard (Royal College of Nursing (Great Britain) : 1987). 2015;29(21):42–48. Epub 2015/01/22 PubMed PMID: 25605115. DOI:10.7748/ns.29.21.42.e9222.
   Google Scholar
• Gattoussi S, Cougnard-Grégoire A, Delyfer MN, et al. Vitreomacular adhesion and its association with age-related macular degeneration in a population-based setting: the alienor study. Invest Ophthalmol Visual Sci. 2017;58(4):2180–2186. Epub 2017/04/12 PubMed PMID: 28399268. DOI:10.1167/iovs.16-20741.
   PubMed Web of Science ®Google Scholar
• Spector A. Review: oxidative stress and disease. J Ocul Pharmacol Ther. 2000;16(2):193–201. Epub 2000/05/10 PubMed PMID: 10803430. DOI:10.1089/jop.2000.16.193.
   PubMed Web of Science ®Google Scholar
• Yan Y, Yu H, Sun L, et al. Laminin alpha4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract. Aging (Albany NY). 2019;11(9):2699–2723. PubMed PMID: 31076560; PubMed Central PMCID: PMC6535067. DOI:10.18632/aging.101943.
   PubMedGoogle Scholar
• Zhao X, Cai Y, Xu J. Circular RNAs: biogenesis, mechanism, and function in human cancers. Int J Mol Sci. 2019;20(16):3926. PubMed PMID: 31412535; PubMed Central PMCID: PMC6720291. DOI:10.3390/ijms20163926.
   PubMed Web of Science ®Google Scholar
• Zhou WY, Cai ZR, Liu J, et al. Circular RNA: metabolism, functions and interactions with proteins. Mol Cancer. 2020;19(1):172. PubMed PMID: 33317550; PubMed Central PMCID: PMC7734744. DOI:10.1186/s12943-020-01286-3.
   PubMed Web of Science ®Google Scholar
• Panda AC. Circular RNAs act as miRNA sponges. advances in experimental medicine and biology. 2018;1087: 67–79. Epub 2018/09/28 PubMed PMID: 30259358. DOI:10.1007/978-981-13-1426-1_6.
   Google Scholar
• Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20(11):675–691. Epub 2019/08/10 PubMed PMID: 31395983. DOI:10.1038/s41576-019-0158-7.
   PubMed Web of Science ®Google Scholar
• Fabian MR, Sonenberg N, Filipowicz W. Regulation of mRNA translation and stability by microRnas. Annu Rev Biochem. 2010;79(1):351–379. Epub 2010/06/11 PubMed PMID: 20533884. DOI:10.1146/annurev-biochem-060308-103103.
   PubMed Web of Science ®Google Scholar
• Shan K, Liu C, Liu BH, et al. Circular noncoding RNA HIPK3 mediates retinal vascular dysfunction in diabetes mellitus. Circulation. 2017;136(17):1629–1642. Epub 2017/09/02 PubMed PMID: 28860123. DOI:10.1161/circulationaha.117.029004.
   PubMed Web of Science ®Google Scholar
• Zhang SJ, Chen X, Li CP, et al. Identification and characterization of circular RNAs as a new class of putative biomarkers in diabetes retinopathy. Invest Ophthalmol Visual Sci. 2017;58(14):6500–6509. PubMed PMID: 29288268. DOI:10.1167/iovs.17-22698.
   PubMed Web of Science ®Google Scholar
• Han J, Gao L, Dong J, et al. The expression profile of developmental stage-dependent circular RNA in the immature rat retina. Mol Vis. 2017;23: 457–469. Epub 2017/08/02. PubMed PMID: 28761319; PubMed Central PMCID: PMCPmc5524268.
   PubMed Web of Science ®Google Scholar
• Liu X, Liu B, Zhou M, et al. Circular RNA HIPK3 regulates human lens epithelial cells proliferation and apoptosis by targeting the miR-193a/cryaa axis. Biochem Biophys Res Commun. 2018;503(4):2277–2285. PubMed PMID: 29959922. DOI:10.1016/j.bbrc.2018.06.149.
   PubMed Web of Science ®Google Scholar
• Tay Y, Rinn J, Pandolfi PP. The multilayered complexity of ceRNA crosstalk and competition. Nature. 2014;505(7483):344–352. Epub 2014/01/17 PubMed PMID: 24429633; PubMed Central PMCID: PMCPmc4113481. DOI10.1038/nature12986.
   PubMed Web of Science ®Google Scholar
• Cannell IG, Kong YW, Bushell M. How do microRnas regulate gene expression? Biochem Soc Trans. 2008;36(Pt 6):1224–1231. PubMed PMID: 19021530. DOI:10.1042/BST0361224.
   PubMedGoogle Scholar
• Zhang C, Hu J, Yu Y. CircRNA is a rising star in researches of ocular diseases. Frontiers in cell and developmental biology. 2020;8:850. PubMed PMID: 33015046; PubMed Central PMCID: PMC7494781. DOI:10.3389/fcell.2020.00850.
   Google Scholar
• Guo N, Liu XF, Pant OP, et al. Circular RNAs: novel promising biomarkers in ocular diseases. Int J Med Sci. 2019;16(4):513–518. Epub 2019/06/07 PubMed PMID: 31171902; PubMed Central PMCID: PMCPmc6535655. DOI:10.7150/ijms.29750.
   PubMed Web of Science ®Google Scholar
• Michael R, Bron AJ. The ageing lens and cataract: a model of normal and pathological ageing. Philos Trans R Soc London Ser B Biol Sci. 2011;366(1568):1278–1292. PubMed PMID: 21402586; PubMed Central PMCID: PMC3061107. DOI:10.1098/rstb.2010.0300.
   PubMed Web of Science ®Google Scholar
• Cui G, Wang L, Huang W. Circular RNA HIPK3 regulates human lens epithelial cell dysfunction by targeting the miR-221-3p/pi3k/akt pathway in age-related cataract. Exp Eye Res. 2020;198:108128. PubMed PMID: 32681842.
   PubMed Web of Science ®Google Scholar
• Xu X, Gao R, Li S, et al. Circular RNA circZNF292 regulates H(2) O(2) -induced injury in human lens epithelial HLE-B3 cells depending on the regulation of the miR-222-3p/e2f3 axis. Cell Biol Int. 2021;45(8):1757–1767. Epub 2021/04/15 PubMed PMID: 33851769. DOI:10.1002/cbin.11615.
   PubMed Web of Science ®Google Scholar
• Che X, Zhao Q, Li D. Expression of thioredoxin-2 in human lens epithelial cells with oxidative damage and its significance]. Zhong nan da xue xue bao Yi xue ban =. J Central South Univ Med Sci. 2018;43(3):253–259. Epub 2018/04/28 PubMed PMID: 29701186. DOI:10.11817/j.issn.1672-7347.2018.03.004.
   Google Scholar
• Liu J, Zhang J, Zhang G, et al. CircMRE11A_013 binds to UBXN1 and integrates ATM activation enhancing lens epithelial cells senescence in age-related cataract. Aging (Albany NY). 2021;13(4):5383–5402. PubMed PMID: 33508783; PubMed Central PMCID: PMC7950295. DOI:10.18632/aging.202470.
   PubMedGoogle Scholar
• Chen M, Zhang C, Zhou N, et al. Metformin alleviates oxidative stress-induced senescence of human lens epithelial cells via AMPK activation and autophagic flux restoration. J Cell Mol Med. 2021;25(17):8376–8389. PubMed PMID: 34296521; PubMed Central PMCID: PMC8419182. DOI:10.1111/jcmm.16797.
   PubMed Web of Science ®Google Scholar
• Del Caño G G, Montaña M, Aretxabala X, et al. Nuclear phospholipase C-β1 and diacylglycerol LIPASE-α in brain cortical neurons. Adv Biol Regul. 2014;54: 12–23. Epub 2013/10/01 PubMed PMID: 24076015. DOI:10.1016/j.jbior.2013.09.003.
   PubMedGoogle Scholar
• Barker CJ, Li L, Köhler M, et al. β-Cell Ca(2+) dynamics and function are compromised in aging. Adv Biol Regul. 2015;57:112–119. Epub 2014/10/06 PubMed PMID: 25282681.
   PubMedGoogle Scholar
• Nakamura Y, Kanemarum K, Fukami K. Physiological functions of phospholipase Cδ1 and phospholipase Cδ3. Adv Biol Regul. 2013;53(3):356–362. Epub 2013/08/21 PubMed PMID: 23948486. DOI:10.1016/j.jbior.2013.07.003.
   PubMedGoogle Scholar
• Arteaga CL, Johnson MD, Todderud G, et al. Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas. Proc Natl Acad Sci USA. 1991;88(23):10435–10439. Epub 1991/12/01 PubMed PMID: 1683701; PubMed Central PMCID: PMCPmc52943. DOI:10.1073/pnas.88.23.10435.
   PubMed Web of Science ®Google Scholar
• Fu L, Qin YR, Xie D, et al. Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma. Cancer Res. 2007;67(22):10720–10726. Epub 2007/11/17 PubMed PMID: 18006814. DOI:10.1158/0008-5472.can-07-2411.
   PubMed Web of Science ®Google Scholar
• Liu W, Liu X, Wang L, et al. PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells. Oncol Rep. 2018;39(1):45–52. Epub 2017/11/09 PubMed PMID: 29115528; PubMed Central PMCID: PMCPmc5783603. DOI:10.3892/or.2017.6080.
   PubMed Web of Science ®Google Scholar
• Xiang J, Chen Q, Kang L, et al. LncRNA PLCD3-OT1 functions as a CeRNA to prevent age-related cataract by sponging miR-224-5p and regulating PLCD3 expression. Invest Ophthalmol Visual Sci. 2019;60(14):4670–4680. Epub 2019/11/15 PubMed PMID: 31725166. DOI:10.1167/iovs.19-27211.
   PubMed Web of Science ®Google Scholar