1,662
Views
0
CrossRef citations to date
0
Altmetric
Research Paper

Tanshinone increases Hemopexin expression in lung cells and macrophages to protect against cigarette smoke-induced COPD and enhance antiviral responses

, , , , , & show all
Pages 645-665 | Received 10 May 2022, Accepted 26 Sep 2022, Published online: 11 Oct 2022

References

  • Barnes PJ, Burney PG, Silverman EK, et al. Chronic obstructive pulmonary disease. Nat Rev Dis Primers. 2015;1:15076.
  • Sheikh K, Coxson HO, Parraga G. This is what COPD looks like. Respirology. 2016;21:224–236.
  • Corlateanu A, Odajiu I, Botnaru V, et al. From smoking to COPD–current approaches. Pneumologia. 2016;65:20–23.
  • Hou W, Hu S, Li C, et al. Cigarette smoke induced lung barrier dysfunction, EMT, and tissue remodeling: a possible link between COPD and lung cancer. Biomed Res Int. 2019;2019:2025636.
  • Barnes PJ. Cellular and molecular mechanisms of chronic obstructive pulmonary disease. Clin Chest Med. 2014;35:71–86.
  • Barnes PJ. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2016;138:16–27.
  • Caramori G, Casolari P, Barczyk A, et al. COPD immunopathology. Semin Immunopathol. 2016;38:497–515.
  • Rahman I. The role of oxidative stress in the pathogenesis of COPD: implications for therapy. Treat Respir Med. 2005;4:175–200.
  • Kirkham PA, Barnes PJ. Oxidative stress in COPD. Chest. 2013;144:266–273.
  • Han W, Dong Z, Dimitropoulou C, et al. Hydrogen sulfide ameliorates tobacco smoke-induced oxidative stress and emphysema in mice. Antioxid Redox Signal. 2011;15:2121–2134.
  • Seemungal TA, Donaldson GC, Paul EA, et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1998;157:1418–1422.
  • Donaldson GC, Seemungal TA, Bhowmik A, et al. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57:847–852.
  • Soler-Cataluna JJ, Martinez-Garcia MA, Roman Sanchez P, et al. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax. 2005;60:925–931.
  • Mallia P, Contoli M, Caramori G, et al. Exacerbations of asthma and chronic obstructive pulmonary disease (COPD): focus on virus induced exacerbations. Curr Pharm Des. 2007;13:73–97.
  • Kato H, Sato S, Yoneyama M, et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity. 2005;23(1):19–28. DOI:10.1016/j.immuni.2005.04.010.
  • Matsumoto M, Oshiumi H, Seya T. Antiviral responses induced by the TLR3 pathway. Rev Med Virol. 2011;21:67–77.
  • Negishi H, Taniguchi T, Yanai H. The Interferon (IFN) class of cytokines and the IFN Regulatory Factor (IRF) transcription factor family. Cold Spring Harb Perspect Biol. 2018;10:10.
  • Stanifer ML, Guo C, Doldan P, et al. Importance of type I and III interferons at respiratory and intestinal barrier surfaces. Front Immunol. 2020;11:608645.
  • Stetson DB, Medzhitov R. Type I interferons in host defense. Immunity. 2006;25:373–381.
  • Kotenko SV, Gallagher G, Baurin VV, et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol. 2003;4:69–77.
  • Ichikawa A, Kuba K, Morita M, et al. CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am J Respir Crit Care Med. 2013;187:65–77.
  • Wu W, Zhang W, Booth JL, et al. Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses. Respir Res. 2016;17:111.
  • Jiang Z, Gao W, Huang L. Tanshinones, critical pharmacological components in salvia miltiorrhiza. Front Pharmacol. 2019;10:202.
  • Zhang K, Wang J, Jiang H, et al. Tanshinone IIA inhibits lipopolysaccharide-induced MUC1 overexpression in alveolar epithelial cells. Am J Physiol Cell Physiol. 2014;306:C59–65.
  • Li D, Wang J, Sun D, et al. Tanshinone IIA sulfonate protects against cigarette smoke-induced COPD and down-regulation of CFTR in mice. Sci Rep. 2018;8:376.
  • Li D, Sun D, Yuan L, et al. Sodium tanshinone IIA sulfonate protects against acute exacerbation of cigarette smoke-induced chronic obstructive pulmonary disease in mice. Int Immunopharmacol. 2020;81:106261.
  • Groves HT, McDonald JU, Langat P, et al. Mouse models of influenza infection with circulating strains to test seasonal vaccine efficacy. Front Immunol. 2018;9:126.
  • Ponnuraj EM, Hayward AR, Raj A, et al. Increased replication of respiratory syncytial virus (RSV) in pulmonary infiltrates is associated with enhanced histopathological disease in bonnet monkeys (Macaca radiata) pre-immunized with a formalin-inactivated RSV vaccine. J Gen Virol. 2001;82:2663–2674.
  • Khansari N, Shakiba Y, Mahmoudi M. Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Recent Pat Inflamm Allergy Drug Discov. 2009;3:73–80.
  • Cormet-Boyaka E, Jolivette K, Bonnegarde-Bernard A, et al. An NF-kappaB-independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium. Toxicol Sci. 2012;125:418–429.
  • N’Guessan PD, Temmesfeld-Wollbruck B, Zahlten J, et al. Moraxella catarrhalis induces ERK- and NF-kappaB-dependent COX-2 and prostaglandin E2 in lung epithelium. Eur Respir J. 2007;30:443–451.
  • Swanson KV, Deng M, Ting JP. The NLRP3 inflammasome: molecular activation and regulation to therapeutics. Nat Rev Immunol. 2019;19:477–489.
  • Garcia-Valero J, Olloquequi J, Montes JF, et al. Deficient pulmonary IFN-beta expression in COPD patients. PLoS One. 2019;14:e0217803.
  • Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol. 2009;4:435–459.
  • Hardaker EL, Freeman MS, Dale N, et al. Exposing rodents to a combination of tobacco smoke and lipopolysaccharide results in an exaggerated inflammatory response in the lung. Br J Pharmacol. 2010;160:1985–1996.
  • Zhou Y, Tan X, Kuang W, et al. Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats. Transl Res. 2012;159:464–472.
  • Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J. 2006;28:219–242.
  • Schuliga M. NF-kappaB signaling in chronic inflammatory airway disease. Biomolecules. 2015;5:1266–1283.
  • Zaynagetdinov R, Sherrill TP, Gleaves LA, et al. Chronic NF-kappaB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs. Oncotarget. 2016;7:5470–5482.
  • Zhou L, Liu Y, Chen X, et al. Over-expression of nuclear factor-kappaB family genes and inflammatory molecules is related to chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2018;13:2131–2138.
  • Su Y, Han W, Kovacs-Kasa A, et al. HDAC6 activates ERK in airway and pulmonary vascular remodeling of chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2021;65:603–614.
  • Defnet AE, Hasday JD, Shapiro P. Kinase inhibitors in the treatment of obstructive pulmonary diseases. Curr Opin Pharmacol. 2020;51:11–18.
  • Colarusso C, Terlizzi M, Molino A, et al. Role of the inflammasome in chronic obstructive pulmonary disease (COPD). Oncotarget. 2017;8:81813–81824.
  • Zhang J, Xu Q, Sun W, et al. New insights into the role of NLRP3 inflammasome in pathogenesis and treatment of chronic obstructive pulmonary disease. J Inflamm Res. 2021;14:4155–4168.
  • Wang H, Lv C, Wang S, et al. NLRP3 inflammasome involves in the acute exacerbation of patients with chronic obstructive pulmonary disease. Inflammation. 2018;41:1321–1333.
  • Tolosano E, Altruda F. Hemopexin: structure, function, and regulation. DNA Cell Biol. 2002;21:297–306.
  • Winter NA, Gibson PG, Fricker M, et al. Hemopexin: a novel anti-inflammatory marker for distinguishing COPD from asthma. Allergy Asthma Immunol Res. 2021;13:450–467.
  • Hsu AC, Parsons K, Moheimani F, et al. Impaired antiviral stress granule and IFN-beta enhanceosome formation enhances susceptibility to influenza infection in chronic obstructive pulmonary disease epithelium. Am J Respir Cell Mol Biol. 2016;55:117–127.
  • Mallia P, Message SD, Gielen V, et al. Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation. Am J Respir Crit Care Med. 2011;183:734–742.
  • D’Anna SE, Maniscalco M, Cappello F, et al. Bacterial and viral infections and related inflammatory responses in chronic obstructive pulmonary disease. Ann Med. 2021;53:135–150.