Inhibition by Salmeterol and Cilomilast of Fluticasone-Enhanced IP-10 Release in Airway Epithelial Cells

REFERENCES

• Levine S J, Larivee P, Logun C, Angus C W, Shelhamer J H. Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line. AmJ Physiol 1993; 265: 360–368
   Google Scholar
• Kwon O J, Au B T, Collins P D, Adcock I M, Mak J C, Robbins R R, Chung K F, Barnes P J. Tumor necrosis factor-induced IL-8 expression in human airway cells. AmJ Physiol Lung Cell Mol Physiol 1994; 267: L398–405
   PubMed Web of Science ®Google Scholar
• Stellato C, Beck L A, Gorgone G A, Proud D, Schall T J, Ono S J, Lichtenstein L M, Schleimer R P. Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and gluccorticoids. J Immunol 1995; 155: 410–418
   PubMed Web of Science ®Google Scholar
• Korn S H, Jerre A, Brattsand R. Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells. Eur RespirJ 2001; 17: 1070–1077
   PubMed Web of Science ®Google Scholar
• Chang M MJ, Juarez M, Hyde D M, Wu R. Mechanism of dexamethasone-mediated interleukin-8 gene suppression in cultured airway epithelial cells. AmJ Physiol Lung Cell Mol Physiol 2001; 280: 107–115
   Web of Science ®Google Scholar
• Escotte S, Tabary O, Dusser D, Majer-Teboul C, Puchelle E, Jacquot J. Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-beta kinase pathway. Eur RespirJ 2003; 21: 574–581
   PubMed Web of Science ®Google Scholar
• Necela B M, Cidlowski J A. Mechanisms of glucocorticoid receptor action in noninflammatory and inflammatory cells. Proc Am Thorac Soc 2004; 1: 239–246
   PubMedGoogle Scholar
• Mahler D A, Wire P, Horstman D, Chang C N, Yates J, Fischer T, Shah T. Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease. AmJ Respir Crit Care Med 2002; 166: 1084–1091
   PubMed Web of Science ®Google Scholar
• Calverley P, Pauwels R, Vestbo J, Jones P, Pride N, Gulsvik A, Anderson J, Maden C. TRial of Inhaled Steroids and long-acting beta2 agonists study group. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomized controlled trial. Lancet 2003; 361: 449–456
   PubMed Web of Science ®Google Scholar
• Woolcock A, Lundback B, Ringdal N, Jacques L A. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. AmJ Respir Crit Care Med 1996; 153: 1481–1488
   PubMed Web of Science ®Google Scholar
• Pauwels R A, Lofdahl C G, Postma D S, Tattersfield A E, O'Byrne P, Barnes P J, Ullman A. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N EnglJ Med 1997; 337: 1405–1411
   PubMed Web of Science ®Google Scholar
• Hancox R J, Cowan C O, Flannery E M, Herbison G P, McLachlan C R, Wong C S, Taylor D R. Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma. Thorax 1999; 54: 482–487
   PubMed Web of Science ®Google Scholar
• Goleva E, Dunlap A, Leung D YM. Differential control of TH1 versus TH2 cell responses by the combination of low-dose steroids with beta2-adrenergic agonists. J Allergy Clin Immunol 2004; 114: 183–191
   PubMed Web of Science ®Google Scholar
• Peek E J, Richards D F, Faith A, Lavender P, Lee T H, Corrigan C J, Hawrylowicz C M. Interleukin-10-secreting “regulatory” T cells induced by glucocorticoids and beta2-agonists. AmJ Respir Cell Mol Biol 2005; 33: 105–111
   PubMed Web of Science ®Google Scholar
• Pang L, Knox A J. Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells. AmJ Respir Cell Mol Biol 2000; 23: 79–85
   PubMed Web of Science ®Google Scholar
• Eickelberg O, Roth M, Lorx R, Bruce V, Rudiger J, Johnson M, Block L H. Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J Biol Chem 1999; 274: 1005–1010
   PubMed Web of Science ®Google Scholar
• Usmani O S, Ito K, Maneechotesuwan K, Ito M, Johnson M, Barnes P J, Adcock I M. Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy. AmJ Respir Crit Care Med 2005; 172: 704–712
   PubMed Web of Science ®Google Scholar
• Nie M, Knox A J, Pang L. Beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation. J Immunol 2005; 175: 478–486
   PubMed Web of Science ®Google Scholar
• D'Ambrosio D, Mariani M, Panina-Bordignon P, Sinigaglia F. Chemokines and their receptors guiding T-lymphocyte recruitment in lung inflammation. AmJ Respir Crit Care Med 2001; 164: 1266–1275
   PubMed Web of Science ®Google Scholar
• Barnes P J, Shapiro S D, Pauwels R A. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur RespirJ 2003; 22: 672–688
   PubMed Web of Science ®Google Scholar
• Spurrell J CL, Wiehler S, Zaheer R S, Sanders S P, Proud D. Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection. AmJ Physiol Lung Cell Mol Physiol 2005; 289: L85–L95
   PubMed Web of Science ®Google Scholar
• Sauty A, Dziejman M, Taha R A, Iarossi A S, Neote K, Garcia-Zepeda E A, Hamid Q, Luster A D. TheT cell-specific CXC chemokines IP-10, MIG, and I-TAC are expressed by activated human bronchial epithelial cells. J Immunol 1999; 162: 3549–3558
   PubMed Web of Science ®Google Scholar
• Whiting D, Hsieh G, Yun J J, Banerji A, Yao W, Fishbein M C, Belperio J, Strieter R M, Bonavida B, Ardehali A. Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production. J Immunol 2004; 172: 7417–7424
   PubMed Web of Science ®Google Scholar
• Sabatini F, Silvestri M, Sale R, Serpero L, Raynal M E, Di Blasi P, Rossi G A. Modulation of the constitutive or cytokine-induced bronchial epithelial cell functions in vitro by fluticasone propionate. Immunol Lett 2003; 89: 215–224
   PubMed Web of Science ®Google Scholar
• Noah T L, Wortman I A, Becker S. The effect of fluticasone propionate on respiratory syncytial virus-induced chemokine release by a human bronchial epithelial cell line. Immunopharmacology 1998; 39: 193–199
   PubMedGoogle Scholar
• Ek A, Palmberg L, Larsson K. Influence of fluticasone and salmeterol on airway effects of inhaled organic dust; an in vivo ex vivo study. Clin Exp Immunol 2000; 121: 11–16
   PubMed Web of Science ®Google Scholar
• Chung K F. Cytokines in chronic obstructive pulmonary disease. Eur RespirJ Suppl 2001; 34: 50s–59s
   PubMed Web of Science ®Google Scholar
• Penn R B, Kelsen S G, Benovic J L. Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells. AmJ Respir Cell Mol Biol 1994; 11: 496–505
   PubMed Web of Science ®Google Scholar
• Aksoy M O, Mardini I A, Yang Y, Bin W, Zhou S, Kelsen S G. Glucocorticoid effects on the beta-adrenergic receptor-adenylyl cyclase system of human airway epithelium. J Allergy Clin Immunol 2002; 109: 491–497
   PubMed Web of Science ®Google Scholar
• Yu Y, Chadee K. Prostaglandin E2 stimulates IL-8 gene expression in human colonic epithelial cells by a posttranscriptional mechanism. J Immunol 1998; 161: 3746–3752
   PubMed Web of Science ®Google Scholar
• Kanda N, Watanabe S. 17 beta-estradiol inhibits the production of interferon-induced protein of 10 kDa by human keratinocytes. J Invest Dermatol 2003; 120: 411–419
   PubMed Web of Science ®Google Scholar
• Saetta M, Mariani M, Panina-Bordignon P, Turato G, Buonsanti C, Baraldo S, Bellettato C M, Papi A, Corbetta L, Zuin R, Sinigaglia F, Fabbri L M. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. AmJ Respir Crit Care Med 2002; 165: 1404–1409
   PubMed Web of Science ®Google Scholar
• Fukakusa M, Bergeron C, Tulic M K, Fiset P-O, Al Dewachi O, Laviolette M, Hamid Q, Chakir J. Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-gamma-inducible protein 10 expression in asthmatic airway mucosa. J Allergy Clin Immunol 2005; 115: 280–286
   PubMed Web of Science ®Google Scholar
• Delgado M. Inhibition of interferon (IFN) gamma-induced Jak-STAT1 activation in microglia by vasoactive intestinal peptide: inhibitory effect on CD40, IFN-induced protein-10, and inducible nitric-oxide synthase expression. J Biol Chem 2003; 278: 27620–27629
   PubMed Web of Science ®Google Scholar
• Keatings V M, Collins P D, Scott D M, Barnes P J. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. AmJ Respir Crit Care Med 1996; 153: 530–534
   PubMed Web of Science ®Google Scholar
• Bochner B S, Hudson S A, Xiao H Q, Liu M C. Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions. J Allergy Clin Immunol 2003; 112: 930–934
   PubMed Web of Science ®Google Scholar
• Hardaker E L, Bacon A M, Carlson K, Roshak A K, Foley J J, Schmidt D B, Buckley P T, Comegys M, Panettieri R A, Jr, Sarau H M, Belmonte K E. Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease. FASEB J 2004; 18: 191–193
   PubMed Web of Science ®Google Scholar
• Medoff B D, Sauty A, Tager A M, Maclean J A, Smith R N, Mathew A, Dufour J H, Luster A D. IFN-gamma-inducible protein 10 (CXCL10) contributes to airway hyperreactivity and airway inflammation in a mouse model of asthma. J Immunol 2002; 168: 5278–5286
   PubMed Web of Science ®Google Scholar