Oxygen Uptake and Lactate Kinetics in Patients with Chronic Obstructive Pulmonary Disease during Heavy Intensity Exercise: Role of Pedaling Cadence

References

• Poole DC, Barstow TJ, Gaesser GA, Willis WT, Whipp BJ. VO2 slow component: physiological and functional significance. Med Sci Sports Exerc. 1994;26(11):1354–1358.
   PubMed Web of Science ®Google Scholar
• Whipp BJ. The slow component of O2 uptake kinetics during heavy exercise. Med Sci Sports Exerc. 1994;26(11):1319–1326.
   PubMed Web of Science ®Google Scholar
• Roston WL, Whipp BJ, Davis JA, Cunningham DA, Effros RM, Wasserman K. Oxygen uptake kinetics and lactate concentration during exercise in humans. Am Rev Respir Dis. 1987;135(5):1080–1804.
   PubMedGoogle Scholar
• Whipp BJ, Wasserman K. Oxygen uptake kinetics for various intensities of constant-load work. J Appl Physiol. 1972;33(3):351–356.
   PubMed Web of Science ®Google Scholar
• Krustrup P, Jones AM, Wilkerson DP, Calbet JA, Bangsbo J. Muscular and pulmonary O2 uptake kinetics during moderate- and high-intensity sub-maximal knee-extensor exercise in humans. J Physiol. 2009;587(Pt 8):1843–1856.
   PubMed Web of Science ®Google Scholar
• Poole DC, Schaffartzik W, Knight DR, Derion T, Kennedy B, Guy HJ, Prediletto R, Wagner PD. Contribution of exercising legs to the slow component of oxygen uptake kinetics in humans. J Appl Physiol. 1991;71(4):1245–1260.
   PubMed Web of Science ®Google Scholar
• Krustrup P, Soderlund K, Mohr M, Bangsbo J. The slow component of oxygen uptake during intense, sub-maximal exercise in man is associated with additional fibre recruitment. Pflugers Arch. 2004;447(6):855–866.
   PubMed Web of Science ®Google Scholar
• Cannon DT, White AC, Andriano MF, Kolkhorst FW, Rossiter HB. Skeletal muscle fatigue precedes the slow component of oxygen uptake kinetics during exercise in humans. J Physiol. 2011;589(Pt 3):727–739.
   PubMed Web of Science ®Google Scholar
• Barstow TJ, Casaburi R, Wasserman K. O2 uptake kinetics and the O2 deficit as related to exercise intensity and blood lactate. J Appl Physiol. 1993;75(2):755–762.
   PubMed Web of Science ®Google Scholar
• Casaburi R, Storer TW, Ben-Dov I, Wasserman K. Effect of endurance training on possible determinants of VO2 during heavy exercise. J Appl Physiol. 1987;62(1):199–207.
   PubMed Web of Science ®Google Scholar
• Poole DC, Ward SA, Gardner GW, Whipp BJ. Metabolic and respiratory profile of the upper limit for prolonged exercise in man. Ergonomics. 1988;31(9):1265–1279.
   PubMed Web of Science ®Google Scholar
• Zoladz JA, Korzeniewski B. Physiological background of the change point in VO2 and the slow component of oxygen uptake kinetics. J Physiol Pharmacol. 2001;52(2):167–184.
   PubMed Web of Science ®Google Scholar
• Jones AM, Grassi B, Christensen PM, Krustrup P, Bangsbo J, Poole DC. Slow component of VO2 kinetics: mechanistic bases and practical applications. Med Sci Sports Exerc. 2011;43(11):2046–2462.
   PubMed Web of Science ®Google Scholar
• Barstow TJ, Jones AM, Nguyen PH, Casaburi R. Influence of muscle fiber type and pedal frequency on oxygen uptake kinetics of heavy exercise. J Appl Physiol. 1996;81(4):1642–1650.
   PubMed Web of Science ®Google Scholar
• Endo MY, Kobayakawa M, Kinugasa R, Kuno S, Akima H, Rossiter HB, Miura A, Fukuba Y. Thigh muscle activation distribution and pulmonary VO2 kinetics during moderate, heavy, and very heavy intensity cycling exercise in humans. Am J Physiol Regul Integr Comp Physiol. 2007;293(2):R812–R820.
   PubMed Web of Science ®Google Scholar
• Ahlquist LE, Bassett DR, Jr., Sufit R, Nagle FJ, Thomas DP. The effect of pedaling frequency on glycogen depletion rates in type I and type II quadriceps muscle fibers during submaximal cycling exercise. Eur J Appl Physiol Occup Physiol. 1992;65(4):360–364.
   PubMed Web of Science ®Google Scholar
• Sargeant AJ. Human power output and muscle fatigue. Int J Sports Med. 1994;15(3):116–121.
   PubMed Web of Science ®Google Scholar
• Böning D, Gonen Y, Maassen N. Relationship between work load, pedal frequency, and physical fitness. Int J Sports Med. 1984;5(2):92–97.
   PubMed Web of Science ®Google Scholar
• Gosker HR, van Mameren H, van Dijk PJ, Engelen MP, van der Vusse GJ, Wouters EF, Schols AM. Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease. Eur Respir J. 2002;19(4):617–625.
   PubMed Web of Science ®Google Scholar
• Jobin J, Maltais F, Doyon JF, LeBlanc P, Simard PM, Simard AA, Simard C. Chronic obstructive pulmonary disease: capillarity and fiber-type characteristics of skeletal muscle. J Cardiopulm Rehabil. 1998;18(6):432–437.
   PubMedGoogle Scholar
• Mador MJ, Bozkanat E. Skeletal muscle dysfunction in chronic obstructive pulmonary disease. Respir Res. 2001;2(4):216–224.
   PubMed Web of Science ®Google Scholar
• Maltais F, LeBlanc P, Whittom F, Simard C, Marquis K, Belanger M, Breton MJ, Jobin J. Oxidative enzyme activities of the vastus lateralis muscle and the functional status in patients with COPD. Thorax. 2000;55(10):848–853.
   PubMed Web of Science ®Google Scholar
• Saey D, Michaud A, Couillard A, Cote CH, Mador MJ, LeBlanc P, Jobin J, Maltais F. Contractile fatigue, muscle morphometry, and blood lactate in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2005;171(10):1109–1115.
   PubMed Web of Science ®Google Scholar
• Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med. 1999;159(1):179–187.
   PubMed Web of Science ®Google Scholar
• Sue DY, Wasserman K, Moricca RB, Casaburi R. Metabolic acidosis during exercise in patients with chronic obstructive pulmonary disease. Use of the V-slope method for anaerobic threshold determination. Chest. 1988;94(5):931–938.
   PubMed Web of Science ®Google Scholar
• Huszczuk A, Whipp BJ, Wasserman K. A respiratory gas exchange simulator for routine calibration in metabolic studies. Eur Respir J. 1990;3(4):465–468.
   PubMed Web of Science ®Google Scholar
• Porszasz J, Woodhouse L, Casaburi R, Nguyen A, Tsurugaya H, Whipp BJ. Use of physiological calibration to validate gas exchange measurements during exercise. Med Sci Sports Exerc. 2004;36(5):S27.
   Web of Science ®Google Scholar
• McLoughlin P, Popham P, Linton RA, Bruce RC, Band DM. Use of arterialized venous blood sampling during incremental exercise tests. J Appl Physiol. 1992;73(3):937–940.
   PubMed Web of Science ®Google Scholar
• Whipp BJ, Ward SA, Lamarra N, Davis JA, Wasserman K. Parameters of ventilatory and gas exchange dynamics during exercise. J Appl Physiol Respir Environ Exerc Physiol. 1982;52(6):1506–1513.
   PubMed Web of Science ®Google Scholar
• Motulsky HJ, Ransnas LA. Fitting curves to data using nonlinear regression: a practical and nonmathematical review. FASEB J. 1987;1(5):365–374.
   PubMed Web of Science ®Google Scholar
• Ozyener F, Rossiter HB, Ward SA, Whipp BJ. Influence of exercise intensity on the on- and off-transient kinetics of pulmonary oxygen uptake in humans. J Physiol. 2001;533(Pt 3):891–902.
   PubMed Web of Science ®Google Scholar
• Lamarra N, Whipp BJ, Ward SA, Wasserman K. Effect of interbreath fluctuations on characterizing exercise gas exchange kinetics. J Appl Physiol. 1987;62(5):2003–2012.
   PubMed Web of Science ®Google Scholar
• Pringle JS, Doust JH, Carter H, Tolfrey K, Campbell IT, Sakkas GK, Jones AM. Oxygen uptake kinetics during moderate, heavy and severe intensity ″submaximal″ exercise in humans: the influence of muscle fibre type and capillarisation. Eur J Appl Physiol. 2003;89(3–4):289–300.
   PubMed Web of Science ®Google Scholar
• Whipp BJ, Rossiter HB, Ward SA. Exertional oxygen uptake kinetics: a stamen of stamina? Biochem Soc Trans. 2002;30(2):237–247.
   PubMedGoogle Scholar
• Pringle JS, Doust JH, Carter H, Tolfrey K, Jones AM. Effect of pedal rate on primary and slow-component oxygen uptake responses during heavy-cycle exercise. J Appl Physiol. 2003;94(4):1501–1507.
   PubMed Web of Science ®Google Scholar
• Hirai DM, Roseguini BT, Diefenthaeler F, Carpes FP, Vaz MA, Ferlin EL, Ribeiro JP, Nakamura FY. Effects of altering pedal frequency on the slow component of pulmonary VO2 kinetics and EMG activity. Int J Sports Med. 2010;31(8):529–536.
   PubMed Web of Science ®Google Scholar
• Crow MT, Kushmerick MJ. Chemical energetics of slow- and fast-twitch muscles of the mouse. J Gen Physiol. 1982;79(1):147–166.
   PubMed Web of Science ®Google Scholar
• Han YS, Geiger PC, Cody MJ, Macken RL, Sieck GC. ATP consumption rate per cross bridge depends on myosin heavy chain isoform. J Appl Physiol. 2003;94(6):2188–2196.
   PubMed Web of Science ®Google Scholar
• Hunter GR, Newcomer BR, Larson-Meyer DE, Bamman MM, Weinsier RL. Muscle metabolic economy is inversely related to exercise intensity and type II myofiber distribution. Muscle Nerve. 2001;24(5):654–661.
   PubMed Web of Science ®Google Scholar
• Krustrup P, Soderlund K, Mohr M, Bangsbo J. Slow-twitch fiber glycogen depletion elevates moderate-exercise fast-twitch fiber activity and O2 uptake. Med Sci Sports Exerc. 2004;36(6):973–982.
   PubMed Web of Science ®Google Scholar
• Beelen A, Sargeant AJ. Effect of fatigue on maximal power output at different contraction velocities in humans. J Appl Physiol. 1991;71(6):2332–2337.
   PubMed Web of Science ®Google Scholar
• He ZH, Bottinelli R, Pellegrino MA, Ferenczi MA, Reggiani C. ATP consumption and efficiency of human single muscle fibers with different myosin isoform composition. Biophys J. 2000;79(2):945–961.
   PubMed Web of Science ®Google Scholar
• Barstow TJ, Mole PA. Linear and nonlinear characteristics of oxygen uptake kinetics during heavy exercise. J Appl Physiol. 1991;71(6):2099–2106.
   PubMed Web of Science ®Google Scholar
• Koga S, Rossiter HB, Heinonen I, Musch TI, Poole DC. Dynamic heterogeneity of exercising muscle blood flow and O2 utilization. Med Sci Sports Exerc. 2014;46(5):860–876.
   PubMed Web of Science ®Google Scholar