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Original Articles

Relationship between Blood and Induced Sputum Eosinophils, Bronchial Hyperresponsiveness and Reversibility of Airway Obstruction in Mild-to-Moderate Chronic Obstructive Pulmonary Disease

, , , , , , & show all
Pages 354-361 | Received 14 May 2019, Accepted 26 Sep 2019, Published online: 21 Oct 2019

References

  • Hoenderdos K, Condliffe A. The neutrophil in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2013;48(5):531–539. doi:10.1165/rcmb.2012-0492TR.
  • Górska K, Maskey-Warzęchowska M, Krenke R. Airway inflammation in chronic obstructive pulmonary disease. Curr Opin Pulm Med. 2010;16(2):89–96. doi:10.1097/MCP.0b013e3283341ba0.
  • Górska K, Paplińska-Goryca M, Nejman-Gryz P, et al. Eosinophilic and neutrophilic airway inflammation in the phenotyping of mild-to-moderate asthma and chronic obstructive pulmonary disease. COPD. 2017;14(2):181–189. doi:10.1080/15412555.2016.1260539.
  • Saha S, Brightling CE. Eosinophilic airway inflammation in COPD. Int J Chron Obstruct Pulmon Dis. 2006;1(1):39–47.
  • Leigh R, Pizzichini MMM, Morris MM, et al. Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment. Eur Respir J. 2006;27(5):964–971.
  • Brightling CE, McKenna S, Hargadon B, et al. Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax. 2005;60(3):193–198. doi:10.1136/thx.2004.032516.
  • Bafadhel M, McKenna S, Terry S, et al. Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med. 2011;184(6):662–671. doi:10.1164/rccm.201104-0597OC.
  • Baines KJ, Pavord ID, Gibson PG. The role of biomarkers in the management of airways disease. Int J Tuberc Lung Dis. 2014;18(11):1264–1268. doi:10.5588/ijtld.14.0226.
  • Wagener AH, de Nijs SB, Lutter R, et al. External validation of blood eosinophils, FE(NO) and serum periostin as surrogates for sputum eosinophils in asthma. Thorax. 2015;70(2):115–120. doi:10.1136/thoraxjnl-2014-205634.
  • Fowler SJ, Tavernier G, Niven R. High blood eosinophil counts predict sputum eosinophilia in patients with severe asthma. J Allergy Clin Immunol. 2015;135(3):822–824.e2. doi:10.1016/j.jaci.2014.09.034.
  • Westerhof GA, Korevaar DA, Amelink M, et al. Biomarkers to identify sputum eosinophilia in different adult asthma phenotypes. Eur Respir J. 2015;46(3):688–696. doi:10.1183/09031936.00012415.
  • Casanova C, Celli BR, de-Torres JP, et al. Prevalence of persistent blood eosinophilia: relation to outcomes in patients with COPD. Eur Respir J. 2017;50(5):1701162. doi:10.1183/13993003.01162-2017.
  • Singh D, Kolsum U, Brightling CE, et al. Eosinophilic inflammation in COPD: prevalence and clinical characteristics. Eur Respir J. 2014;44(6):1697–1700. doi:10.1183/09031936.00162414.
  • Kim VL, Coombs NA, Staples KJ, et al. Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort. Eur Respir J. 2017;50.
  • Weiszhar Z, Horvath I. Induced sputum analysis: step by step. Breathe. 2013;9(4):300–306. doi:10.1183/20734735.042912.
  • Hastie AT, Martinez FJ, Curtis JL, et al. Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017;5(12):956–967.
  • Gorska K, Nejman-Gryz P, Paplinska-Goryca M, et al. Comparative study of IL-33 and IL-6 levels in different respiratory samples in mild-to-moderate asthma and COPD. COPD. 2018;15(1):36–45. doi:10.1080/15412555.2017.1416074.
  • Gorska K, Krenke R, Domagala-Kulawik J, et al. Comparison of cellular and biochemical markers of airway inflammation in patients with mild-to-moderate asthma and chronic obstructive pulmonary disease: an induced sputum and bronchoalveolar lavage fluid study. J Physiol Pharmacol Off J Pol Physiol Soc. 2008;59 Suppl 6:271–283.
  • Diagnosis of Diseases of Chronic Airflow limitation: Asthma, COPD and Asthma-COPD Overlap Syndrome (ACOS) [Internet]. Glob. Initiat. Asthma – GINA; 2015 [cited 2019 Apr 26]. Available from: https://ginasthma.org/asthma-copd-and-asthma-copd-overlap-syndrome-acos/.
  • Vignola AM, Rennar SI, Hargreave FE, et al. Standardised methodology of sputum induction and processing. Future directions. Eur Respir J Suppl. 2002;37:51s–55s.
  • Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J. 2005;26(2):319–338. doi:10.1183/09031936.05.00034805.
  • Guidelines for Methacholine and Exercise Challenge Testing—1999. Am J Respir Crit Care Med. 2000;161:309–329.
  • Samoliński B, Raciborski F, Lipiec A, et al. Epidemiologia Chorób Alergicznych w Polsce (ECAP). Alergol Pol – Pol J Allergol. 2014;1(1):10–18. doi:10.1016/j.alergo.2014.03.008.
  • Gold Reports 2018 [Internet]. Glob. Initiat. Chronic Obstr. Lung Dis. – GOLD. [cited 2019 Jan 25]. Available from: https://goldcopd.org/gold-reports/.
  • Negewo NA, McDonald VM, Baines KJ, et al. Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD. COPD. 2016;11:1495–1504. doi:10.2147/COPD.S100338.
  • Dransfield MT, Bourbeau J, Jones PW, et al. Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials. Lancet Respir Med. 2013;1(3):210–223. doi:10.1016/S2213-2600(13)70040-7.
  • Fagiolo U, Cossarizza A, Scala E, et al. Increased cytokine production in mononuclear cells of healthy elderly people. Eur J Immunol. 1993;23(9):2375–2378. doi:10.1002/eji.1830230950.
  • Valiathan R, Ashman M, Asthana D. Effects of ageing on the immune system: infants to elderly. Scand J Immunol. 2016;83(4):255–266. doi:10.1111/sji.12413.
  • Mathur SK, Schwantes EA, Jarjour NN, et al. Age-related changes in eosinophil function in human subjects. Chest. 2008;133(2):412–419. doi:10.1378/chest.07-2114.
  • DiSantostefano RL, Hinds D, Le HV, et al. Relationship between blood eosinophils and clinical characteristics in a cross-sectional study of a US population-based COPD cohort. Respir Med. 2016;112:88–96. doi:10.1016/j.rmed.2016.01.013.
  • Zanini A, Cherubino F, Zampogna E, et al. Bronchial hyperresponsiveness, airway inflammation, and reversibility in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2015;10:1155–1161.
  • van den Berge M, Vonk JM, Gosman M, et al. Clinical and inflammatory determinants of bronchial hyperresponsiveness in COPD. Eur Respir J. 2012;40(5):1098–1105. doi:10.1183/09031936.00169711.
  • Wardlaw AJ, Dunnette S, Gleich GJ, et al. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am Rev Respir Dis. 1988;137(1):62–69. doi:10.1164/ajrccm/137.1.62.
  • Janson C, Chinn S, Jarvis D, et al. Effect of passive smoking on respiratory symptoms, bronchial responsiveness, lung function, and total serum IgE in the European Community Respiratory Health Survey: a cross-sectional study. Lancet Lond Engl. 2001;358(9299):2103–2109. doi:10.1016/S0140-6736(01)07214-2.
  • Schwartz J, Schindler C, Zemp E, et al. Predictors of methacholine responsiveness in a general population. Chest. 2002;122(3):812–820. doi:10.1378/chest.122.3.812.
  • Juusela M, Pallasaho P, Rönmark E, et al. Dose-dependent association of smoking and bronchial hyperresponsiveness. Eur Respir J. 2013;42(6):1503–1512. doi:10.1183/09031936.00073712.
  • Dima E, Rovina N, Gerassimou C, et al. Pulmonary function tests, sputum induction, and bronchial provocation tests: diagnostic tools in the challenge of distinguishing asthma and COPD phenotypes in clinical practice. Int J Chron Obstruct Pulmon Dis. 2010;5:287–296.
  • Papi A, Romagnoli M, Baraldo S, et al. Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2000;162(5):1773–1777. doi:10.1164/ajrccm.162.5.9910112.

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