Biomarkers as a Prognostic Factor in COPD Exacerbation: A Cohort Study

References

• Caballero A, Torres-Duque CA, Jaramillo C, et al. Prevalence of COPD in five Colombian cities situated at low, medium, and high altitude (PREPOCOL study). Chest. 2008;133(2):343–349. DOI:10.1378/chest.07-1361
   PubMed Web of Science ®Google Scholar
• Snow V, Joint Expert Panel on Chronic Obstructive Pulmonary Disease of the American College of Chest Physicians and the American College of Physicians-American Society of Internal Medicine, Lascher S, Mottur-Pilson C. Joint Expert Panel on Chronic Obstructive Pulmonary Disease of the American College of Chest P, the American College of Physicians-American Society of Internal M. Evidence base for management of acute exacerbations of chronic obstructive pulmonary disease. Ann Intern Med. 2001;134(7):595–599. DOI:10.7326/0003-4819-134-7-200104030-00015
   PubMed Web of Science ®Google Scholar
• Echevarria C, Steer J, Heslop-Marshall K, et al. Validation of the DECAF score to predict hospital mortality in acute exacerbations of COPD. Thorax. 2016;71(2):133–140. DOI:10.1136/thoraxjnl-2015-207775
   PubMed Web of Science ®Google Scholar
• Asiimwe AC, Brims FJ, Andrews NP, et al. Routine laboratory tests can predict in-hospital mortality in acute exacerbations of COPD. Lung. 2011;189(3):225–232. DOI:10.1007/s00408-011-9298-z
   PubMed Web of Science ®Google Scholar
• Patel AR, Hurst JR, Wedzicha JA. The potential value of biomarkers in diagnosis and staging of COPD and exacerbations. Semin Respir Crit Care Med. 2010;31(3):267–275. DOI:10.1055/s-0030-1254067
   PubMed Web of Science ®Google Scholar
• Kim CH, Kim SJ, Lee MJ, et al. An increase in mean platelet volume from baseline is associated with mortality in patients with severe sepsis or septic shock. PLoS One. 2015;10(3):e0119437. DOI:10.1371/journal.pone.0119437
   PubMed Web of Science ®Google Scholar
• Ulasli SS, Ozyurek BA, Yilmaz EB, et al. Mean platelet volume as an inflammatory marker in acute exacerbation of chronic obstructive pulmonary disease. Pol Arch Med Wewn. 2012;122(6):284–290. DOI:10.20452/pamw.1284
   PubMed Web of Science ®Google Scholar
• Duman D, Aksoy E, Agca MC, et al. The utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophilia. Int J Chron Obstruct Pulmon Dis. 2015;10:2469–2478. DOI:10.2147/COPD.S90330
   PubMed Web of Science ®Google Scholar
• Afari ME, Bhat T. Neutrophil to lymphocyte ratio (NLR) and cardiovascular diseases: an update. Expert Rev Cardiovasc Ther. 2016;14(5):573–577. DOI:10.1586/14779072.2016.1154788
   PubMed Web of Science ®Google Scholar
• Rahimirad S, Ghaffary MR, Rahimirad MH, et al. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease. Tuberk Toraks. 2017;64(1):25–31. DOI:10.5578/tt.27626
   Google Scholar
• Salturk C, Karakurt Z, Adiguzel N, et al. Does eosinophilic COPD exacerbation have a better patient outcome than non-eosinophilic in the intensive care unit? Int J Chron Obstruct Pulmon Dis. 2015;10:1837–1846. DOI:10.2147/COPD.S88058
   PubMed Web of Science ®Google Scholar
• Steiropoulos P, Papanas N, Nena E, et al. Mean platelet volume and platelet distribution width in patients with chronic obstructive pulmonary disease: the role of comorbidities. Angiology. 2013;64(7):535–539. DOI:10.1177/0003319712461436
   PubMed Web of Science ®Google Scholar
• Wu CW, Lan CC, Hsieh PC, et al. Role of peripheral eosinophilia in acute exacerbation of chronic obstructive pulmonary disease. WJCC. 2020;8(13):2727–2737. DOI:10.12998/wjcc.v8.i13.2727
   PubMed Web of Science ®Google Scholar
• Wu HX, Zhuo KQ, Cheng DY. Peripheral blood eosinophil as a biomarker in outcomes of acute exacerbation of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2019;14:3003–3015. DOI:10.2147/COPD.S226783
   PubMed Web of Science ®Google Scholar
• Brusselle G, Pavord ID, Landis S, et al. Blood eosinophil levels as a biomarker in COPD. Respir Med. 2018;138:21–31. DOI:10.1016/j.rmed.2018.03.016
   PubMed Web of Science ®Google Scholar
• You Y, Shi GC. Blood eosinophils and clinical outcome of acute exacerbations of chronic obstructive pulmonary disease: A systematic review and meta-analysis. Respiration. 2021;100(3):228–237. DOI:10.1159/000510516
   PubMed Web of Science ®Google Scholar
• Koh CH, Bhoo-Pathy N, Ng KL, et al. Utility of pre-treatment neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as prognostic factors in breast cancer. Br J Cancer. 2015;113(1):150–158. DOI:10.1038/bjc.2015.183
   PubMed Web of Science ®Google Scholar
• Charles KA, Harris BD, Haddad CR, et al. Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and non-oropharyngeal patients. BMC Cancer. 2016;16:124. DOI:10.1186/s12885-016-2089-4
   PubMed Web of Science ®Google Scholar
• Murphy C, Turner N, Wong HL, et al. Examining the impact of regular aspirin use and PIK3CA mutations on survival in stage 2 colon cancer. Intern Med J. 2017;47(1):88–98. DOI:10.1111/imj.13312
   PubMed Web of Science ®Google Scholar
• Pine JK, Morris E, Hutchins GG, et al. Systemic neutrophil-to-lymphocyte ratio in colorectal cancer: the relationship to patient survival, tumour biology and local lymphocytic response to tumour. Br J Cancer. 2015;113(2):204–211. DOI:10.1038/bjc.2015.87
   PubMed Web of Science ®Google Scholar
• Mallappa S, Sinha A, Gupta S, et al. Preoperative neutrophil to lymphocyte ratio >5 is a prognostic factor for recurrent colorectal cancer. Colorectal Dis. 2013;15(3):323–328. DOI:10.1111/codi.12008
   PubMed Web of Science ®Google Scholar
• Hung HY, Chen JS, Yeh CY, et al. Effect of preoperative neutrophil-lymphocyte ratio on the surgical outcomes of stage II colon cancer patients who do not receive adjuvant chemotherapy. Int J Colorectal Dis. 2011;26(8):1059–1065. DOI:10.1007/s00384-011-1192-x
   PubMed Web of Science ®Google Scholar
• Orkin S, Nathan D, Ginsburg D, et al. Nathan and Oski's Hematology and Oncology of Infancy and Childhood E-Book. Eighth edition. [Internet]. Saunders; 2014. [cited 2020 Mar 8]. available at https://books.google.com.co/books?id=gjWaBQAAQB AJ&pg=PA952&lpg=PA952&dq=normal±mean±platelet±volume± 10±femtoliters&source=bl&ots=Lpjcb1JxhW&sig=ACfU3U3LSjfkK hvvrAG-idjb2-CsIhx4qw&hl=es&sa=X&ved=2ahUKEwia9d2uwovo AhUGKa0KHXeiAsMQ6AEwEXoECAoQAQ#v=onepage&q=normal mean platelet volume 10 femtoliters&f=false.
   Google Scholar
• Kolsum U, Donaldson GC, Singh R, et al. Blood and sputum eosinophils in COPD; relationship with bacterial load. Respir Res. 2017;18(1):88. DOI:10.1186/s12931-017-0570-5
   PubMed Web of Science ®Google Scholar
• Singh D, ECLIPSE investigators, Kolsum U, Brightling CE, Locantore N, Agusti A, Tal-Singer R. Eosinophilic inflammation in COPD: prevalence and clinical characteristics. Eur Respir J. 2014;44(6):1697–1700. DOI:10.1183/09031936.00162414
   PubMed Web of Science ®Google Scholar
• Argeny S, Stift A, Bergmann M, et al. Prognostic value of preoperative neutrophil-to-lymphocyte ratio in Crohn's disease. Wien Klin Wochenschr. 2018;130(11-12):398–403. DOI:10.1007/s00508-018-1322-3
   PubMed Web of Science ®Google Scholar
• Li KH. Imputation using markov chains. J Stat Comput Simul. 1988;30(1):57–79. DOI:10.1080/00949658808811085
   Google Scholar
• Paliogiannis P, Fois AG, Sotgia S, et al. Neutrophil to lymphocyte ratio and clinical outcomes in COPD: recent evidence and future perspectives. Eur Respir Rev. 2018;27(147):170113. DOI:10.1183/16000617.0113-2017
   PubMed Web of Science ®Google Scholar
• Faria SS, Fernandes PC, Jr., Silva MJ, et al. The neutrophil-to-lymphocyte ratio: a narrative review. Ecancermedicalscience. 2016;10:702. DOI:10.3332/ecancer.2016.702
   PubMed Web of Science ®Google Scholar
• Curbelo J, Rajas O, Arnalich B, et al. Neutrophil count percentage and neutrophil-lymphocyte ratio as prognostic markers in patients hospitalized for community-acquired pneumonia. Arch Bronconeumol. 2019;55(9):472–477. DOI:10.1016/j.arbres.2019.02.005
   PubMed Web of Science ®Google Scholar
• Soliman WM, Sherif NM, Ghanima IM, et al. Neutrophil to lymphocyte and platelet to lymphocyte ratios in systemic lupus erythematosus: Relation with disease activity and lupus nephritis. Reumatol Clin. 2020;16(4):255–261. DOI:10.1016/j.reuma.2018.07.008
   PubMed Web of Science ®Google Scholar
• Caramori G, Casolari P, Barczyk A, et al. COPD immunopathology. Semin Immunopathol. 2016;38(4):497–515. DOI:10.1007/s00281-016-0561-5
   PubMed Web of Science ®Google Scholar
• Lee H, Um SJ, Kim YS, et al. Association of the Neutrophil-to-lymphocyte ratio with lung function and exacerbations in patients with chronic obstructive pulmonary disease. PLoS One. 2016;11(6):e0156511. DOI:10.1371/journal.pone.0156511
   PubMed Web of Science ®Google Scholar
• Yao C, Liu X, Tang Z. Prognostic role of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio for hospital mortality in patients with AECOPD. COPD. 2017; 12:2285–2290. DOI:10.2147/COPD.S141760
   Google Scholar
• Liu J, Liu J, Zou Y. Relationship between neutrophil-lymphocyte ratio and short-term prognosis in the chronic obstructive pulmonary patients with acute exacerbation. Biosci Rep. 2019;39(5):BSR20190675. DOI:10.1042/BSR20190675
   Google Scholar
• Gava G, Nunez A, Esquinas C, et al. Analysis of blood biomarkers in patients with Chronic Obstructive Pulmonary Disease (COPD) and with Asthma-COPD Overlap (ACO). COPD. 2020;17(3):306–310. DOI:10.1080/15412555.2020.1761314
   PubMedGoogle Scholar
• Xiong W, Xu M, Zhao Y, et al. Can we predict the prognosis of COPD with a routine blood test? Int J Chron Obstruct Pulmon Dis. 2017;12:615–625. DOI:10.2147/COPD.S124041
   PubMed Web of Science ®Google Scholar
• Chis AF, Pop CM. Correlations between neutrophil to lymphocyte ratio, blood eosinophils and clinical characteristics in chronic obstructive pulmonary disease. Med Pharm Rep. 2020;93(2):169–174. DOI:10.15386/mpr-1412
   PubMedGoogle Scholar
• Rajasurya V, Gudivada D. Neutrophil lymphocyte ratio in predicting outcome for hospitalized patients with acute exacerbation of COPD. Chest. 2019;156(4):A159. DOI:10.1016/j.chest.2019.08.233
   Web of Science ®Google Scholar
• Greulich T, Tuffers J, Mager S, et al. High eosinophil blood counts are associated with a shorter length of hospital stay in exacerbated COPD patients - a retrospective analysis. Respir Res. 2020;21(1):106. DOI:10.1186/s12931-020-01365-5
   PubMed Web of Science ®Google Scholar
• MacDonald MI, Osadnik CR, Bulfin L, et al. Low and high blood eosinophil counts as biomarkers in hospitalized acute exacerbations of COPD. Chest. 2019;156(1):92–100. DOI:10.1016/j.chest.2019.02.406
   PubMed Web of Science ®Google Scholar
• Erden E, Dokuyucu R, Demirköse M, et al. Assessment of mean platelet volume in chronic obstructive pulmonary disease during stable period and acute exacerbation. J Clin Exp Invest. 2013;4(4):483–487. DOI:10.5799/ahinjs.01.2013.04.0329
   Google Scholar
• Gil Y, Torres C, Figueredo M, et al. Estimación de la prevalencia de EPOC en Colombia a partir del Registro Individual de Prestaciones de Servicios de Salud (RIPS). Rev Colomb Neumol. 2019;31(1):5–15. DOI:10.30789/rcneumologia.v31.n1.2019.325
   Google Scholar