Reference
- Agustí A, Vogelmeier C, Faner R. COPD 2020: changes and challenges. Am J Physiol Lung Cell Mol Physiol. 2020;319(5):L879–L883. doi:10.1152/ajplung.00429.2020.
- Vogelmeier CF, Román-Rodríguez M, Singh D, et al. Goals of COPD treatment: focus on symptoms and exacerbations. Respir Med. 2020;166:105938. doi:10.1016/j.rmed.2020.105938.
- Şerifoğlu İ, Ulubay G. The methods other than spirometry in the early diagnosis of COPD. Tuberk Toraks. 2019;67(1):63–70. doi:10.5578/tt.68162.
- Christenson SA, Smith BM, Bafadhel M, et al. Chronic obstructive pulmonary disease. Lancet. 2022;399(10342):2227–2242. doi:10.1016/S0140-6736(22)00470-6.
- Duffy SP, Criner GJ. Chronic obstructive pulmonary disease: evaluation and management. Med Clin North Am. 2019;103(3):453–461. doi:10.1016/j.mcna.2018.12.005.
- Silverman EK. Genetics of COPD. Annu Rev Physiol. 2020;82(1):413–431. doi:10.1146/annurev-physiol-021317-121224.
- Joo J, Himes B. Gene-Based analysis reveals Sex-Specific genetic risk factors of COPD AMIA Annual Symposium proceedings AMIA Symposium. 2021;p. 601–610.
- van Iersel LEJ, Beijers R, Gosker HR, et al. Nutrition as a modifiable factor in the onset and progression of pulmonary function impairment in COPD: a systematic review. Nutr Rev. 2022;80(6):1434–1444. doi:10.1093/nutrit/nuab077.
- Yang IA, Jenkins CR, Salvi SS. Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment. Lancet Respir Med. 2022;10(5):497–511. doi:10.1016/S2213-2600(21)00506-3.
- Singh D. Pharmacological treatment of stable chronic obstructive pulmonary disease. Respirology. 2021;26(7):643–651. doi:10.1111/resp.14046.
- Tavernier J, Devos R, Cornelis S, et al. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. Cell. 1991;66(6):1175–1184. doi:10.1016/0092-8674(91)90040-6.
- Roboz GJ, Rafii S. Interleukin-5 and the regulation of eosinophil production. Curr Opin Hematol. 1999;6(3):164–168. doi:10.1097/00062752-199905000-00007.
- Laffey KG, Du J, Schrum AG, et al. Transcriptional regulation of the human IL5RA gene through alternative promoter usage during eosinophil development. Int J Mol Sci. 2021;22(19):10245. doi:10.3390/ijms221910245.
- Singh D, Bassi M, Balzano D, et al. COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type-2 and PDE4 gene expression in sputum. J Cell Mol Med. 2021;25(2):905–918. doi:10.1111/jcmm.16146.
- Narendra DK, Hanania NA. Targeting IL-5 in COPD. Int J Chron Obstruct Pulmon Dis. 2019;14:1045–1051. doi:10.2147/COPD.S155306.
- Khorasanizadeh M, Eskian M, Assa’ad AH, et al. Efficacy and safety of benralizumab, a monoclonal antibody against IL-5Rα, in uncontrolled eosinophilic asthma. Int Rev Immunol. 2016;35(4):294–311. doi:10.3109/08830185.2015.1128901.
- Li JX, Fu WP, Zhang J, et al. A functional SNP upstream of the ADRB2 gene is associated with COPD. Int J Chron Obstruct Pulmon Dis. 2018;13:917–925. doi:10.2147/COPD.S151153.
- Jing J, Xu D, Li Z, et al. Genetic variation of six specific SNPs of chronic obstructive pulmonary disease among Chinese population. Pulmonology. 2022;4:1–9. doi:10.1016/j.pulmoe.2022.02.004.
- Abudureheman Z, Li L, Zhong X, et al. The rs74794265 SNP of the SREK1 gene is associated with COPD in kashi, China. Int J Chron Obstruct Pulmon Dis. 2021;16:2631–2636. doi:10.2147/COPD.S321150.
- Fu Y, Liu L, Wu H. Role of genetic polymorphisms in IL12Rβ2 in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2022;17:1671–1683. doi:10.2147/COPD.S366844.
- Wang Y, Zhou Q, Chen L, et al. Identification of genetic variants of the IL-22 gene in association with an altered risk of COPD susceptibility. Clin Respir J. 2022;16(8):537–545. doi:10.1111/crj.13517.
- Cheong HS, Kim LH, Park BL, et al. Association analysis of interleukin 5 receptor alpha subunit (IL5RA) polymorphisms and asthma. J Hum Genet. 2005;50(12):628–634. doi:10.1007/s10038-005-0304-2.
- Burgstaller S, Kreil S, Waghorn K, et al. The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus. Leukemia. 2007;21(12):2428–2432. doi:10.1038/sj.leu.2404977.
- Miyake Y, Tanaka K, Arakawa M. IL5RA polymorphisms, smoking and eczema in japanese women: the kyushu Okinawa maternal and child health study. Int J Immunogenet. 2015;42(1):52–57. doi:10.1111/iji.12172.
- Ovsyannikova IG, Kennedy RB, O’Byrne M, et al. Genome-wide association study of antibody response to smallpox vaccine. Vaccine. 2012;30(28):4182–4189. doi:10.1016/j.vaccine.2012.04.055.
- Holmans PA, Riley B, Pulver AE, et al. Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. Mol Psychiatry. 2009;14(8):786–795. doi:10.1038/mp.2009.11.
- Yang Y, Mao J, Ye Z, et al. Risk factors of chronic obstructive pulmonary disease among adults in Chinese mainland: a systematic review and meta-analysis. Respir Med. 2017;131:158–165. doi:10.1016/j.rmed.2017.08.018.
- Jing J, Xu D, Li Z, et al. Genetic variants in MIR2113 and MIR129-LEP are associated with the susceptibility of COPD in the Chinese Han population. Pulm Pharmacol Ther. 2020;64:101945. doi:10.1016/j.pupt.2020.101945.
- Zhou X, Zhang Y, Zhang Y, et al. LINC01414/LINC00824 genetic polymorphisms in association with the susceptibility of chronic obstructive pulmonary disease. BMC Pulm Med. 2021;21(1):213. doi:10.1186/s12890-021-01579-3.
- Tang L, Zhong X, Gong H, et al. Analysis of the association of ANO3/MUC15, COL4A4, RRBP1, and KLK1 polymorphisms with COPD susceptibility in the Kashi population. BMC Pulm Med. 2022;22(1):178. doi:10.1186/s12890-022-01975-3.
- Obeidat M, Zhou G, Li X, et al. The genetics of smoking in individuals with chronic obstructive pulmonary disease. Respir Res. 2018;19(1):59. doi:10.1186/s12931-018-0762-7.
- Gong H, Ren J, Xu J, et al. SMAD3 rs36221701 T > C polymorphism impacts COPD susceptibility in the Kashi population. Gene. 2022;808:145970. doi:10.1016/j.gene.2021.145970.
- Kluger R, Burgstaller J, Vogl C, et al. Candidate gene approach identifies six SNPs in tenascin-C (TNC) associated with degenerative rotator cuff tears. J Orthop Res. 2017;35(4):894–901. doi:10.1002/jor.23321.
- Wang S, Yuan X, Liu Y, et al. Genetic polymorphisms of histone methyltransferase SETD2 predicts prognosis and chemotherapy response in Chinese acute myeloid leukemia patients. J Transl Med. 2019;17(1):101. doi:10.1186/s12967-019-1848-9.
- Song J, Hao L, Wei W, et al. A SNP in the 3’UTR of the porcine IGF-1 gene interacts with miR-new14 to affect IGF-1 expression, proliferation and apoptosis of PK-15 cells. Domest Anim Endocrinol. 2020;72:106430. doi:10.1016/j.domaniend.2019.106430.
- Dasgupta A, Neighbour H, Nair P. Targeted therapy of bronchitis in obstructive airway diseases. Pharmacol Ther. 2013;140(3):213–222. doi:10.1016/j.pharmthera.2013.07.001.
- Khatri S, Moore W, Gibson PG, et al. Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma. J Allergy Clin Immunol. 2019;143(5):1742–1751.e7. doi:10.1016/j.jaci.2018.09.033.
- Gibson PG, Prazma CM, Chupp GL, et al. Mepolizumab improves clinical outcomes in patients with severe asthma and comorbid conditions. Respir Res. 2021;22(1):171. doi:10.1186/s12931-021-01746-4.
- Kusano S, Kukimoto-Niino M, Hino N, et al. Structural basis of interleukin-5 dimer recognition by its α receptor. Protein Sci. 2012;21(6):850–864. doi:10.1002/pro.2072.
- Beekman JM, Verhagen LP, Geijsen N, et al. Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output. Blood. 2009;114(18):3917–3927. doi:10.1182/blood-2009-03-208850.
- Martinez-Moczygemba M, Huston DP. Biology of common beta receptor-signaling cytokines: IL-3, IL-5, and GM-CSF. J Allergy Clin Immunol. 2003;112(4):653–665.
- de Groot RP, Coffer PJ, Koenderman L. Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family. Cell Signal. 1998;10(9):619–628. doi:10.1016/s0898-6568(98)00023-0.