Some Key Issues in the Study of Gene–Environment Interplay: Activation, Deactivation, and the Role of Development

REFERENCES

• Anderson , K. E. , Lytton , H. and Romney , D. M. 1986 . Mothers' interactions with normal and conduct-disordered boys: Who affects whom? . Developmental Psychology , 22 : 604 – 609 .
   Web of Science ®Google Scholar
• Barker , E. D. , Seguin , J. R. , White , H. R. , Bates , M. E. , Lacourse , E. , Carbonneau , R. … and Tremblay , R. E. 2007 . Developmental trajectories of male physical violence and theft: Relations to neurocognitive performance . Archives of General Psychiatry , 64 : 592 – 599 .
   PubMed Web of Science ®Google Scholar
• Barker , E. D. , van Lier , P. A. C. , Vitaro , F. , Nagin , D. S. , Assaad , J.-M. , Tremblay , R. E. … and Séguin , J. R. 2011 . The neurocognition of conduct disorder behaviors: Specificity to physical aggression and theft after controlling for ADHD symptoms . Aggressive Behavior , 37 : 63 – 72 .
   PubMed Web of Science ®Google Scholar
• Barkley , R. A. and Cunningham , C. E. 1979 . The effects of methylphenidate on the mother-child interactions of hyperactive children . Archives of General Psychiatry , 36 : 201 – 208 .
   PubMed Web of Science ®Google Scholar
• Barr , C. S. , Newman , T. K. , Becker , M. L. , Parker , C. C. , Champoux , M. , Lesch , K. P. … and Higley , J. D. 2003 . The utility of the non-human primate model for studying gene by environment interactions in behavioral research . Genes, Brain and Behavior , 2 : 336 – 340 .
   PubMed Web of Science ®Google Scholar
• Bester-Meredith , J. K. and Marler , C. A. 2001 . Vasopressin and aggression in cross-fostered California mice (Peromyscus californicus) and White-footed mice (Peromyscus leucopus) . Hormones and Behavior , 40 : 51 – 64 .
   Google Scholar
• Bohman , M . 1996 . Predisposition to ciminality: Sweedish adoption studies in retrospect . Genetics of Criminal and Antisocial Behavior , 194 : 99 – 114 .
   Google Scholar
• Bongers , I. L. , Koot , H. M. , van der Ende , J. and Verhulst , F. C. 2004 . Developmental trajectories of externalizing behaviors in childhood and adolescence . Child Development , 75 : 1523 – 1537 .
   PubMed Web of Science ®Google Scholar
• Brooks-Gunn , J. , Duncan , G. J. , Klebanov , P. K. and Sealand , N. 1993 . Do neighborhoods influence child and adolescent development? . American Journal of Sociology , 99 : 353 – 395 .
   Web of Science ®Google Scholar
• Burt , S. A. 2009a . Are there meaningful etiological differences within antisocial behavior? Results of a meta-analysis . Clinical Psychology Review , 29 : 163 – 178 .
   PubMed Web of Science ®Google Scholar
• Burt , S. A. 2009b . A mechanistic explanation of popularity: Genes, rule-breaking, and evocative gene-environment correlations . Journal of Personality and Social Psychology , 96 : 783 – 794 .
   PubMed Web of Science ®Google Scholar
• Burt , S. A. 2009c . Rethinking environmental contributions to child and adolescent psychopathology: A meta-analysis of shared environmental influences . Psychological Bulletin , 135 : 608 – 637 .
   PubMed Web of Science ®Google Scholar
• Burt , S. A. 2010 . “ The importance of phenotype in explorations of gene-environment interplay ” . In Biosocial foundations of family processes , Edited by: Booth , A. , McHale , S. M. and Landale , N. S. 85 – 94 . New York, NY : Springer .
   Google Scholar
• Burt , S. A. and Donnellan , M. B. 2008 . Personality correlates of aggressive and non-aggressive antisocial behavior . Personality and Individual Differences , 44 : 53 – 63 .
   Web of Science ®Google Scholar
• Burt , S. A. and Klump , K. L. 2009 . The etiological moderation of aggressive antisocial behavior by age . Twin Research & Human Genetics , 12 : 343 – 350 .
   Google Scholar
• Burt , S. A. , Krueger , R. F. , McGue , M. and Iacono , W. G. 2003 . Parent-child conflict and the comorbidity among childhood externalizing disorders . Archives of General Psychiatry , 60 : 505 – 513 .
   PubMed Web of Science ®Google Scholar
• Burt , S. A. , McGue , M. , Demarte , J. A. , Krueger , R. F. and Iacono , W. G. 2006 . Timing of menarche and the origins of conduct disorder . Archives of General Psychiatry , 63 : 890 – 896 .
   PubMed Web of Science ®Google Scholar
• Burt , S. A. , McGue , M. , Krueger , R. F. and Iacono , W. G. 2005 . How are parent-child conflict and child externalizing behaviors related over time? Results from a genetically-informative cross-lagged study . Development and Psychopathology , 17 : 1 – 21 .
   Google Scholar
• Burt , S. A. , McGue , M. , Krueger , R. F. and Iacono , W. G. 2007 . Environmental contributions to adolescent delinquency: A fresh look at the shared environment . Journal of Abnormal Child Psychology , 35 : 787 – 800 .
   PubMedGoogle Scholar
• Burt , S. A. and Neiderhiser , J. M. 2009 . Aggressive versus non-aggressive antisocial behavior: Distinctive etiological moderation by age . Developmental Psychology , 45 : 1164 – 1176 .
   Google Scholar
• Button , T. M. M. , Lau , J. Y. F. , Maughan , B. and Eley , T. C. 2008 . Parental punitive discipline, negative life events, and gene-environment interplay in the development of externalizing behavior . Psychological Medicine , 38 : 29 – 39 .
   Google Scholar
• Cadoret , R. J. , Cain , C. A. and Crowe , R. R. 1983 . Evidence for gene-environment interaction in the development of adolescent antisocial behavior . Behavior Genetics , 13 : 301 – 310 .
   PubMed Web of Science ®Google Scholar
• Cadoret , R. J. , Yates , W. R. , Troughton , E. , Woodworth , G. and Stewart , M. A. 1995 . Genetic-environmental interaction in the genesis of aggressivity and conduct disorders . Archives of General Psychiatry , 52 : 916 – 924 .
   PubMed Web of Science ®Google Scholar
• Caspi , A. , McClay , J. , Moffitt , T. E. , Mill , J. , Martin , J. , Craig , I. W. … and Poulton , R. 2002 . Role of violence in maltreated children . Science , 297 : 851 – 854 .
   PubMed Web of Science ®Google Scholar
• Cleveland , H. H. 2003 . Disadvantaged neighborhoods and adolescent aggression: Behavioral genetic evidence of contextual effects . Journal of Research on Adolescence , 13 : 211 – 238 .
   Web of Science ®Google Scholar
• Côté , S. M. , Vaillancourt , T. , Barker , E. D. , Nagin , D. and Tremblay , R. E. 2007 . The joint development of physical and indirect aggression: Predictors of continuity and change during childhood . Development and Psychopathology , 19 : 37 – 55 .
   PubMed Web of Science ®Google Scholar
• Deater-Deckard , K. 2001 . Annotation: Recent research examining the role of peer relationships in the development of psychopathology . Journal of Child Psychology and Psychiatry , 42 : 565 – 579 .
   PubMed Web of Science ®Google Scholar
• Deater-Deckard , K. , Atzaba-Poria , A. and Pike , A. 2004 . Mother- and father-child mutuality in Anglo and Indian British families: A link with lower externalizing problems . Journal of Abnormal Child Psychology , 32 : 609 – 620 .
   PubMed Web of Science ®Google Scholar
• Deater-Deckard , K. and Petrill , S. A. 2004 . Parent-child mutuality and child behavior problems: An investigation of gene-environment processes . Journal of Child Psychology and Psychiatry , 45 : 1171 – 1179 .
   PubMed Web of Science ®Google Scholar
• Feinberg , M. E. , Button , T. M. M. , Neiderhiser , J. M. , Hetherington , E. M. and Reiss , D. 2007 . Parenting and adolescent antisocial behavior and depression: Evidence for genotype by parenting interaction . Archives of General Psychiatry , 64 : 457 – 465 .
   Google Scholar
• Foley , D. L. , Eaves , L. J. , Wormley , B. , Silberg , J. L. , Maes , H. H. , Kuhn , J. … and Riley , B. 2004 . Childhood adversity, monoamine oxidase A genotype, and risk for conduct disorder . Archives of General Psychiatry , 61 : 738 – 744 .
   PubMed Web of Science ®Google Scholar
• Francis , D. D. , Diorio , J. , Liu , D. and Meaney , M. J. 1999 . Nongenomic transmission across generations in maternal behavior and stress responses in the rat . Science , 286 : 1155 – 1158 .
   PubMed Web of Science ®Google Scholar
• Frick , P. J. , Lahey , B. B. , Loeber , R. , Tannenbaum , L. , Van Horn , Y. , Christ , M. A. G. … and Hanson , K. 1993 . Oppositional defiant disorder and conduct disorder: A meta-analytic review of factor analyses and cross-validation in a clinic sample . Clinical Psychology Review , 13 : 319 – 340 .
   Web of Science ®Google Scholar
• Gardner , M. and Steinberg , L. 2005 . Peer influence on risk taking, risk preference, and risky decision making in adolescence and adulthood: An experimental study . Developmental Psychology , 41 : 625 – 635 .
   PubMed Web of Science ®Google Scholar
• Ge , X. , Conger , R. D. , Cadoret , R. J. and Neiderhiser , J. M. 1996 . The developmental interface between nature and nurture: A mutual influence model of child antisocial behavior and parent behaviors . Developmental Psychology , 32 : 574 – 589 .
   Web of Science ®Google Scholar
• Gorman-Smith , D. , Tolan , P. H. and Henry , D. 1999 . “ The relation of community and family to risk among urban poor adolescents ” . In Where and when: Influence of historical time and place on aspects of psychopathology , Edited by: Cohen , P. , Robins , L. and Slomkowski , C. 349 – 367 . Hillsdale, NJ : Lawrence Erlbaum .
   Google Scholar
• Gorman-Smith , D. , Tolan , P. H. and Henry , D. 2000 . A developmental-ecological model of the relation of family functioning to patterns of delinquency . Journal of Quantitative Criminology , 16 ( 2 ) : 169 – 198 .
   Web of Science ®Google Scholar
• Gottlieb , G. 2007 . Probabilistic epigenesis . Development Science , 10 : 1 – 11 .
   PubMed Web of Science ®Google Scholar
• Haberstick , B. C. , Schmitz , S. , Young , S. E. and Hewitt , J. K. 2005 . Contributions of genes and environments to stability and change in externalizing and internalizing problems during elementary and middle school . Behavior Genetics , 35 : 381 – 396 .
   PubMed Web of Science ®Google Scholar
• Hancock , M. , Tapscott , J. L. and Hoaken , P. N. S. 2010 . Role of executive dysfunction in predicting severity and frequency of violence . Aggressive Behavior , 36 : 338 – 349 .
   PubMed Web of Science ®Google Scholar
• Hicks , B. M. , South , S. C. , DiRago , A. C. , Iacono , W. G. and McGue , M. 2009 . Environmental adversity and increasing genetic risk for externalizing disorders . Archives of General Psychiatry , 66 : 640 – 648 .
   PubMed Web of Science ®Google Scholar
• Huizinga , D. , Haberstick , B. C. , Smolen , A. , Menard , S. , Young , S. E. , Corley , R. P. … and Hewitt , J. K. 2006 . Childhood maltreatment, subsequent antisocial behavior, and the role of the monoamine oxidase A genotype . Biological Psychiatry , 60 : 677 – 683 .
   PubMed Web of Science ®Google Scholar
• Johnson , W. 2007 . Genetic and environmental influences on behavior: Capturing all the interplay . Psychological Review , 114 : 423 – 440 .
   PubMed Web of Science ®Google Scholar
• Kim-Cohen , J. , Caspi , A. , Taylor , A. , Williams , B. , Newcombe , R. , Craig , I. W. … and Moffitt , T. E. 2006 . MAOA, maltreatment, and gene-environment interaction predicting children's mental health: New evidence and a meta-analysis . Molecular Psychiatry , 11 : 903 – 913 .
   PubMed Web of Science ®Google Scholar
• Lahey , B. B. and Waldman , E. D. 2003 . “ A developmental propensity model of the origins of conduct problems during childhood and adolescence ” . In Causes of conduct disorder and juvenile delinquency , 76 – 117 . New York, NY : Guilford Press .
   Google Scholar
• Legrand , L. N. , Keyes , M. A. , McGue , M. , Iacono , W. G. and Krueger , R. F. 2008 . Rural environments reduce the gentic influence on adolescent substance use and rule-breaking behavior . Psychological Medicine , 38 : 1341 – 1350 .
   Google Scholar
• Leventhal , T. and Brooks-Gunn , J. 2000 . The neighborhoods they live in: The effects of neighborhood residence on child and adolescent outcomes . Psychological Bulletin , 126 : 309 – 337 .
   PubMed Web of Science ®Google Scholar
• Lewontin , R. 1995 . Human diversity , New York, NY : Scientific American Library .
   Google Scholar
• Li , J. J. and Lee , S. S. 2010 . Latent class analysis of antisocial behavior: Interaction of serotonin transporter genotype and maltreatment . Journal of Abnormal Child Psychology , 38 : 789 – 801 .
   PubMed Web of Science ®Google Scholar
• Lickliter , R. 2008 . The growth of developmental thought: Implications for a new evolutionary psychology . New Ideas in Psychology , 26 : 353 – 369 .
   Google Scholar
• Lickliter , R. and Honeycutt , H. 2003 . Developmental dynamics: Toward a biologically plausible evolutionary psychology . Psychological Bulletin , 129 : 819 – 835 .
   PubMed Web of Science ®Google Scholar
• Liu , D. , Tannenbaum , L. , Caldji , C. , Francis , D. , Freedman , A. , Sharma , S. and Meaney , M. J. 1997 . Maternal care, hippocampal glucocorticoid receptor gene expression and hypothalamic-pituitary-adrenal responses to stress . Science , 77 : 1659 – 1662 .
   Google Scholar
• Loeber , R. and Schmaling , K. B. 1985 . Empirical evidence for overt and covert patterns of antisocial conduct problems: A meta-analysis . Journal of Abnormal Child Psychology , 13 : 337 – 352 .
   PubMed Web of Science ®Google Scholar
• Loeber , R. and Wikstrom , P. H. 1993 . “ Individual pathways to crime in different types of neighborhoods ” . In Integrating individual and ecological aspects of crime , Edited by: Farrington , D. P. , Sampson , R. J. and Wikstrom , P. H. 169 – 204 . Stockholm, , Sweden : National Council for Crime Prevention .
   Google Scholar
• Lynam , D. R. , Caspi , A. , Moffitt , T. E. , Wikstrom , P. H. , Loeber , R. and Novak , S. 2000 . The interaction between impulsivity and neighborhood context on offending: The effects of impulsivity are stronger in poorer neighborhoods . Journal of Abnormal Psychology , 109 : 563 – 574 .
   PubMed Web of Science ®Google Scholar
• Masten , A. S. , Hubbard , J. J. , Gest , S. D. , Tellegen , A. , Gamezy , N. and Ramirez , M. 1999 . Competence in the context of adversity: Pathways to resilience and maladaptaion from childhood to adolescence . Development and Psychopathology , 11 : 143 – 169 .
   PubMed Web of Science ®Google Scholar
• Mathijssen , J. J. J. P. , Koot , H. M. , Verhulst , F. C. , DeBruyn , E. E. J. and Oud , J. H. L. 1998 . The relationship between mutual family relations and child psychopathology . Journal of Child Psychology and Psychiatry , 39 : 477 – 487 .
   PubMed Web of Science ®Google Scholar
• Meaney , M. J. and Szyf , M. 2005 . Environmental programming of stress responses through DNA methylation: Life at the interface between a dynamic environment and a fixed genome . Dialogues in Clinical Neuroscience , 7 : 103 – 123 .
   PubMedGoogle Scholar
• Miura , H. 2009 . Differences in frontal lobe function between violent and nonviolent conduct disorder in male adolescents . Psychiatry and Clinical Neurosciences , 63 : 161 – 166 .
   PubMed Web of Science ®Google Scholar
• Moffitt , T. E. , Caspi , A. and Rutter , M. 2006 . Measured gene-environment interactions in psychopathology . Perspectives on Psychological Science , 1 : 5 – 27 .
   Web of Science ®Google Scholar
• Monuteax , M. C. , Fitzmaurice , G. , Blacker , D. , Buka , S. L. and Biederman , J. 2004 . Specificity in the familial aggregation of overt and covert conduct diosrder symptoms in a referred attention-deficit hyperactivity disorder sample . Psychological Medicine , 34 : 1113 – 1127 .
   Google Scholar
• Morgan , A. B. and Lilienfeld , S. O. 2000 . A meta-analytic review of the relation between antisocial behavior and neuropsychological measures of executive function . Clinical Psychology Review , 20 ( 1 ) : 113 – 136 .
   PubMed Web of Science ®Google Scholar
• Neiderhiser , J. M. , Reiss , D. , Hetherington , E. M. and Plomin , R. 1999 . Relationships between parenting and adolescent adjustment over time: Genetic and environmental contributions . Developmental Psychology , 35 : 680 – 692 .
   PubMed Web of Science ®Google Scholar
• Odgers , C. L. , Moffitt , T. E. , Tach , L. M. , Sampson , R. J. , Taylor , A. , Matthews , C. L. … and Caspi , A. 2009 . The protective effects of neighbohood collective efficacy on British children growing up in deprivation: A developmental analysis . Developmental Psychology , 45 : 942 – 957 .
   PubMed Web of Science ®Google Scholar
• Patterson , G. R. 1999 . “ A proposal relating a theory of delinquency to societal rates of juvenile crime: Putting Humpty Dumpty together again ” . In Conflict and cohesion in families: Causes and consequences , Edited by: Cox , M. J. and Brooks-Gunn , J. 11 – 35 . Mahwah, NJ : Lawrence Erlbaum .
   Google Scholar
• Patterson , G. R. , DeBaryshe , B. D. and Ramsey , E. 1989 . A developmental perspective on antisocial behavior . American Psychologist , 44 : 329 – 335 .
   PubMed Web of Science ®Google Scholar
• Pedersen , C. A. 2004 . Biological aspects of social bonding and the roots of human violence . Annals New York Academy of Sciences , 1036 : 106 – 127 .
   PubMed Web of Science ®Google Scholar
• Pennington , B. F. , McGrath , L. M. , Rosenberg , J. , Barnard , H. , Smith , S. D. , Willcutt , E. G. … and Olson , R. K. 2009 . Gene x environment interactions in reading disability and attention-deficit/hyperactivity disorder . Developmental Psychology , 45 : 77 – 89 .
   PubMed Web of Science ®Google Scholar
• Pike , A. , McGuire , S. , Hetherington , E. M. , Reiss , D. and Plomin , R. 1996 . Family environment and adolescent depressive symptoms and antisocial behavior: A multivariate genetic analysis . Developmental Psychology , 32 : 590 – 603 .
   Web of Science ®Google Scholar
• Plomin , R. , DeFries , J. C. and Loehlin , J. C. 1977 . Genotype-environment interaction and correlation in the analysis of human behavior . Psychological Bulletin , 84 : 309 – 322 .
   PubMed Web of Science ®Google Scholar
• Purcell , S. 2002 . Variance components model for gene-environment interaction in twin analysis . Twin Research , 5 : 554 – 571 .
   PubMedGoogle Scholar
• Raine , A. 2002 . Biosocial studies of antisocial and violent behavior in children and adolescents: A review . Journal of Abnormal Child Psychology , 30 : 311 – 326 .
   PubMed Web of Science ®Google Scholar
• Rothbaum , F. and Weisz , J. R. 1994 . Parental caregiving and child externalizing behavior in nonclinical samples: A meta-analysis . Psychological Bulletin , 116 : 55 – -74 .
   PubMed Web of Science ®Google Scholar
• Rutter , M. , Moffitt , T. E. and Caspi , A. 2006 . Gene-environment interplay and psychopathology: Multiple varieties but real effects . Journal of Child Psychology and Psychiatry , 47 : 226 – 261 .
   PubMed Web of Science ®Google Scholar
• Rutter , M. , Silberg , J. , O'Connor , T. J. and Simonoff , E. 1999a . Genetics and child psychiatry: I Advances in quantitative and molecular genetics . Journal of Child Psychology and Psychiatry , 40 : 3 – 18 .
   PubMedGoogle Scholar
• Rutter , M. , Silberg , J. , O'Connor , T. J. and Simonoff , E. 1999b . Genetics and child psychiatry: II Empirical research findings . Journal of Child Psychology and Psychiatry , 40 : 19 – 55 .
   PubMed Web of Science ®Google Scholar
• Sampson , R. J. , Raudenbush , S. W. and Earls , F. J. 1997 . Neighborhoods and violent crime: A multilevel study of collective efficacy . Science , 277 August : 918 – 924 .
   PubMed Web of Science ®Google Scholar
• Scarr , S. and McCartney , K. 1983 . How people make their own environments: A theory of genotype-environment effects . Child Development , 54 : 424 – 435 .
   PubMed Web of Science ®Google Scholar
• Shanahan , M. J. and Hofer , S. M. 2005 . Social context and gene-environment interactions: Retrospect and prospect . Journals of Gerontology , 60B : 65 – 76 .
   Google Scholar
• Spatz Widom , C. and Brzustowicz , L. M. 2006 . MAOA and the “cycle of violence”: Childhood abuse and neglect, MAOA genotype, and risk for violent and antisocial behavior . Biological Psychiatry , 60 : 684 – 689 .
   Google Scholar
• Stranger , C. , Achenbach , T. A. and Verhulst , F. C. 1997 . Acceleratred longitiudinal comparisons of aggressive versus deliquent syndromes . Development and Psychopathology , 9 : 43 – 58 .
   Google Scholar
• Stribley , J. M. and Carter , C. S. 1999 . Developmental exposure to vasopressin increases aggression in adult prairie voles . Proceedings of the National Academy of Sciences , 96 : 12601 – 12604 .
   Google Scholar
• Suomi , S. 2003 . “ Social and biological mechanisms underlying impulsive aggression in Rhesus Monkeys ” . In The causes of conduct disorder and serious juvenile delinquency , Edited by: Lahey , B. , Moffitt , T. E. and Caspi , A. 345 – 362 . New York, NY : Guilford .
   Google Scholar
• Tackett , J. L. October 2010 . A hirearchical structure of antisocial behavior and personality in children and adolescents , October , Seattle, WA : Paper presented at the annual meeting of the Society for Research in Psychopathology .
   Google Scholar
• Thapar , A. , Langley , K. , Asherson , P. and Gill , M. 2007 . Gene-environment interplay in attention-deficit hyperactivity disorder and the importance of a developmental perspective . British Journal of Psychiatry , 190 : 1 – 3 .
   PubMed Web of Science ®Google Scholar
• Tremblay , R. E. 2003 . “ Why socialization fails: The case of chronic physical aggression ” . In The causes of conduct disorder and serious juvenile delinquency , Edited by: Lahey , B. , Moffitt , T. E. and Caspi , A. 182 – 224 . New York, NY : Guilford .
   Google Scholar
• Tremblay , R. E. 2010 . Developmental origins of disruptive behaviour problems: The ‘original sin’ hypothesis, epigenetics and their consequences for prevention . Journal of Child Psychology and Psychiatry , 51 : 341 – 367 .
   PubMed Web of Science ®Google Scholar
• Turkheimer , E. , Haley , A. , Waldron , M. , D'Onofrio , B. and Gottesman , I. I. 2003 . Socioeconomic status modifies heritability of IQ in young children . Psychological Science , 14 : 623 – 628 .
   PubMed Web of Science ®Google Scholar
• Tuvblad , C. , Grann , M. and Lichtenstein , P. 2006 . Heritability for adolescent antisocial behavior differs with socioeconomic status: Gene-environment interaction . Journal of Child Psychology and Psychiatry , 47 : 734 – 743 .
   PubMed Web of Science ®Google Scholar
• van Beijsterveldt , C. E. M. , Bartels , M. , Hudziak , J. J. and Boomsma , D. I. 2003 . Causes of stability of aggression from early childhood to adolescence: A longitudinal genetic analysis in Dutch twins . Behavioral Genetics , 33 : 591 – 605 .
   PubMed Web of Science ®Google Scholar
• van Lier , P. A. C. , Vitaro , F. , Barker , E. D. , Koot , H. M. and Tremblay , R. E. 2009 . Developmental links between trajectories of physical violence, vandalism, theft, and alcohol-drug use from childhood to adolescence . Journal of Abnormal Child Psychology , 37 : 481 – 492 .
   Google Scholar
• Verhulst , F. C. and van der Ende , J. 1995 . The eight-year stability of problem behavior in an epidemiologic sample . Pediatric Research , 38 : 612 – 617 .
   PubMed Web of Science ®Google Scholar
• Weaver , I. C. G. , Meaney , M. J. and Szyf , M. 2006 . Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood . Proceedings of the National Academy of Sciences , 103 : 3480 – 3485 .
   PubMed Web of Science ®Google Scholar