References
- Benda, N. M., Seeger, J. P., Lier, D. P., Bellersen, L., Dijk, A. P., Hopman, M. T., & Thijssen, D. H. (2015). Heart failure patients demonstrate impaired changes in brachial artery blood flow and shear rate pattern during moderate-intensity cycle exercise. Experimental Physiology, 100(4), 463–474. https://doi.org/https://doi.org/10.1113/EP085040
- Blackshear, W. M., Phillips, D. J., & Strandness, D. E. (1979). Pulsed Doppler assessment of normal human femoral artery velocity patterns. The Journal of Surgical Research, 27(79), 73–83. https://doi.org/https://doi.org/10.1016/0022-4804(79)90113-6
- Brunt, V. E., Jeckell, A. T., Ely, B. R., Howard, M. J., Thijssen, D. H., & Minson, C. T. (2016). Acute hot water immersion is protective against impaired vascular function following forearm ischemia-reperfusion in young healthy humans. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 311(6), 1060–1067. https://doi.org/https://doi.org/10.1152/ajpregu.00301.2016
- Carter, H. H., Spence, A. L., Atkinson, C. L., Pugh, C. J., Naylor, L. H., & Green, D. J. (2014). Repeated core temperature elevation induces conduit artery adaptation in humans. European Journal of Applied Physiology, 114(4), 859–865. https://doi.org/https://doi.org/10.1007/s00421-013-2817-2
- Charkoudian, N. (2010). Mechanisms and modifiers of reflex induced cutaneous vasodilation and vasoconstriction in humans. Journal of Applied Physiology, 109(4), 1221–1228. https://doi.org/https://doi.org/10.1152/japplphysiol.00298.2010
- Chatzizisis, Y. S., Coskun, A. U., Jonas, M., Edelman, E. R., Feldman, C. L., & Stone, P. H. (2007). Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: Molecular, cellular, and vascular behavior. Journal of the American College of Cardiology, 49(25), 2379–2393. https://doi.org/https://doi.org/10.1016/j.jacc.2007.02.059
- Cooper, K. E., Edholm, O. G., & Mottram, R. F. (1955). The blood flow in skin and muscle of the human forearm. The Journal of Physiology, 128(2), 258–267. https://doi.org/https://doi.org/10.1113/jphysiol.1955.sp005304
- Dawson, E. A., Green, D. J., Cable, N. T., & Thijssen, D. H. (2013). Effects of acute exercise on flow-mediated dilatation in healthy humans. Journal of Applied Physiology, 115(11), 1589–1598. https://doi.org/https://doi.org/10.1152/japplphysiol.00450.2013
- Endo, M., Okada, Y., Rossiter, H. B., Ooue, A., Miura, A., Koga, S., & Fukuba, Y. (2005). Kinetics of pulmonary VO2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise. European Journal of Applied Physiology, 95(5–6), 418–430. https://doi.org/http://doi.org/10.1007/s00421-005-0051-2
- Endo, M. Y., Suzuki, R., Nagahata, N., Hayashi, N., Miura, A., Koga, S., & Fukuba, Y. (2008). Differential arterial blood flow response of splanchnic and renal organs during low-intensity cycling exercise in women. The American Journal of Physiology-Heart and Circulatory Physiology, 294(5), 2322–2326. https://doi.org/https://doi.org/10.1152/ajpheart.91491.2007
- Fukuba, Y., Endo, M. Y., Kondo, A., Kikugawa, Y., Miura, K., Kashima, H., Fujimoto, M., Hayashi, N., Fukuoka, Y., & Koga, S. (2017). Brachial artery blood flow dynamics during sinusoidal leg cycling exercise in humans. Physiological Reports, 5(19), e13456. https://doi.org/https://doi.org/10.14814/phy2.13456
- Godbole, A. S., Lu, X., Guo, X., & Kassab, G. S. (2009). NADPH oxidase has a directional response to shear stress. The American Journal of Physiology-Heart and Circulatory Physiology, 296(1), 152–158. https://doi.org/https://doi.org/10.1152/ajpheart.01251.2007
- Green, D., Cheetham, C., Mavaddat, L., Watts, K., Best, M., Taylor, R., & O’Driscoll, G. (2002). Effect of lower limb exercise on forearm vascular function: Contribution of nitric oxide. The American Journal of Physiology-Heart and Circulatory Physiology, 283(3), 899–907. https://doi.org/https://doi.org/10.1152/ajpheart.00049.2002
- Green, D. J., Bilsborough, W., Naylor, L. H., Reed, C., Wright, J., O’Driscoll, G., & Walsh, J. H. (2005). Comparison of forearm blood flow responses to incremental handgrip and cycle ergometer exercise: Relative contribution of nitric oxide. The Journal of Physiology, 562(pt 2), 617–628. https://doi.org/https://doi.org/10.1113/jphysiol.2004.075929
- Green, D. J., Hopman, M. T., Padilla, J., Laughlin, M. H., & Thijssen, D. H. (2017). Vascular adaptation to exercise in humans: Role of hemodynamic stimuli. Physiological Reviews, 97(2), 495–528. https://doi.org/https://doi.org/10.1152/physrev.00014.2016
- Green, D. J., O’Driscoll, G., Joyner, M. J., & Cable, N. T. (2008). Exercise and cardiovascular risk reduction: Time to update the rationale for exercise? Journal of Applied Physiology, 105(2), 766–768. https://doi.org/https://doi.org/10.1152/japplphysiol.01028.2007
- Higashi, Y., Noma, K., Yoshizumi, M., & Kihara, Y. (2009). Endothelial function and oxidative stress in cardiovascular diseases. Circulation Journal, 73(3), 411–418. https://doi.org/https://doi.org/10.1253/circj.CJ-08-1102
- Ishida, K., Nakamura, T., Kimura, K., Kanno, N., Takahashi, N., Kamijo, Y., & Tajima, F. (2016). Suppression of activation of muscle sympathetic nerve during non-noxious local cooling after the end of local cooling in normal adults. European Journal of Applied Physiology, 116(4), 851–858. https://doi.org/https://doi.org/10.1007/s00421-016-3343-9
- Johnson, J. M. (1979). Responses of forearm blood flow to graded leg exercise in man. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology, 46(3), 457–462. https://doi.org/https://doi.org/10.1152/jappl.1979.46.3.457
- Johnson, J. M., & Park, M. K. (1981). Effect of upright exercise on threshold for cutaneous vasodilation and sweating. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology, 50(4), 814–818. https://doi.org/https://doi.org/10.1152/jappl.1981.50.4.814
- Johnson, J. M., Pérgola, P. E., Liao, F. K., Kellogg, D. L., Jr., & Crandall, C. G. (1995). Skin of the dorsal aspect of human hands and fingers possesses an active vasodilator system. Journal of Applied Physiology, 78(3), 948–954. https://doi.org/https://doi.org/10.1152/jappl.1995.78.3.948
- Johnson, J. M., & Rowell, L. B. (1975). Forearm skin and muscle vascular responses to prolonged leg exercise in man. Journal of Applied Physiology, 39(6), 920–924. https://doi.org/https://doi.org/10.1152/jappl.1975.39.6.920
- Johnson, J. M., Rowell, L. B., & Brengelmann, G. L. (1974). Modification of the skin blood flow-body temperature relationship by upright exercise. Journal of Applied Physiology, 37(6), 880–886. https://doi.org/https://doi.org/10.1152/jappl.1974.37.6.880
- Kellogg, D. L., Jr., Johnson, J. M., & Kosiba, W. A. (1991). Control of internal temperature threshold for active cutaneous vasodilation by dynamic exercise. Journal of Applied Physiology, 71(6), 2476–2482. https://doi.org/https://doi.org/10.1152/jappl.1991.71.6.2476
- Koga, S., Poole, D. C., Shiojiri, T., Kondo, N., Fukuba, Y., Miura, A., & Barstow, T. J. (2005). Comparison of oxygen uptake kinetics during knee extension and cycle exercise. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 288(1), 212–220. https://doi.org/https://doi.org/10.1152/ajpregu.00147.2004
- Laughlin, M. H., Newcomer, S. C., & Bender, S. B. (2008). Importance of hemodynamic forces as signals for exercise-induced changes in endothelial cell phenotype. Journal of Applied Physiology, 104(3), 588–600. https://doi.org/https://doi.org/10.1152/japplphysiol.01096.2007
- Macefield, V. G. (2013). Sympathetic microneurography. In R. MB & D. FS (Eds.), Autonomic Nervous System. Handbook of clinical neurology (Vol. 117, pp. 353–364). Elsevier.
- Manson, J. E., Hu, F. B., Rich-Edwards, J. W., Colditz, G. A., Stampfer, M. J., Willett, W. C., & Hennekens, C. H. (1999). A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. The New England Journal of Medicine, 341(9), 650–658. https://doi.org/https://doi.org/10.1056/NEJM199908263410904
- McAllister, R. M. (1998). Adaptations in control of blood flow with training: Splanchnic and renal blood flows. Medicine and Science in Sports and Exercise, 30(3), 375–381. https://doi.org/https://doi.org/10.1097/00005768-199803000-00006
- McDonald, D. A. (1955). The relation of pulsatile pressure to flow in arteries. The Journal of Physiology, 127(3), 533–552. https://doi.org/https://doi.org/10.1113/jphysiol.1955.sp005275
- Miura, K., Kashima, H., Oue, A., Kondo, A., Watanabe, S., Endo, M. Y., & Fukuba, Y. (2020). Effect of sinusoidal leg cycling exercise period on brachial artery blood flow dynamics in humans. The Journal of Physiological Sciences, 70(1), 23. https://doi.org/https://doi.org/10.1186/s12576-020-00750-5
- Much, T. I., Haidet, G. C., Ordway, G. A., Longhurst, J. C., & MIitchell, J. H. (1987). Training effects on regional blood flow response to maximal exercise in foxhounds. Journal of Applied Physiology, 62(4), 1724–1732. https://doi.org/https://doi.org/10.1152/jappl.1987.62.4.1724
- Naylor, L. H., Carter, H., FitzSimons, M. G., Cable, N. T., Thijssen, D. H., & Green, D. J. (2011). Repeated increases in blood flow, independent of exercise, enhance conduit artery vasodilator function in humans. The American Journal of Physiology-Heart and Circulatory Physiology, 300(2), 664–669. https://doi.org/https://doi.org/10.1152/ajpheart.00985.2010
- Naylor, L. H., Carter, H., FitzSimons, M. G., Cable, N. T., Thijssen, D. H., & Green, D. J. (2014). Acute impact of retrograde shear rate on brachial and superficial femoral artery flow-mediated dilation in humans. Physiological Reports, 2(1), e00193. https://doi.org/https://doi.org/10.1002/phy2.193
- Newcomer, S. C., Thijssen, D. H., & Green, D. J. (2011). Effects of exercise on endothelium and endothelium/smooth muscle cross talk: Role of exercise-induced hemodynamics. Journal of Applied Physiology, 111(1), 311–320. https://doi.org/https://doi.org/10.1152/japplphysiol.00033.2011
- Ooue, A., Ichinose, T., Inoue, Y., Nishiyasu, T., Koga, S., & Kondo, N. (2008). Changes in blood flow in conduit artery and veins of the upper arm during leg exercise in humans. European Journal of Applied Physiology, 103(3), 367–373. https://doi.org/https://doi.org/10.1007/s00421-008-0706-x
- Padilla, J., Simmons, G. H., Bender, S. B., Arce-Esquivel, A. A., Whyte, J. J., & Laughlin, M. H. (2011a). Vascular effects of exercise: Endothelial adaptations beyond active muscle beds. Physiology, 26(3), 132–145. https://doi.org/https://doi.org/10.1152/physiol.00052.2010
- Padilla, J., Simmons, G. H., Vianna, L. C., Davis, M. J., Laughlin, M. H., & Fadel, P. J. (2011b). Brachial artery vasodilatation during prolonged lower limb exercise: Role of shear rate. Experimental Physiology, 96(10), 1019–1027. https://doi.org/https://doi.org/10.1113/expphysiol.2011.059584
- Padilla, J., Young, C. N., Simmons, G. H., Deo, S. H., Newcomer, S. C., Sullivan, J. P., Laughlin, M. H., & Fadel, P. J. (2010). Increased muscle sympathetic nerve activity acutely alters conduit artery shear rate patterns. The American Journal of Physiology-Heart and Circulatory Physiology, 298(4), 1128–1135. https://doi.org/https://doi.org/10.1152/ajpheart.01133.2009
- Paffenbarger, R. S., Jr., Hyde, R. T., Wing, A. L., & Hsieh, C. C. (1986). Physical activity, all-cause mortality, and longevity of college alumni. The New England Journal of Medicine, 314(10), 605–613. https://doi.org/https://doi.org/10.1056/NEJM198603063141003
- Parker, B. A., Trehearn, T. L., & Meendering, J. R. (2009). Pick your poiseuille: Normalizing the shear stimulus in studies of flow-mediated dilation. Journal of Applied Physiology, 107(4), 1357–1359. https://doi.org/https://doi.org/10.1152/japplphysiol.91302.2009
- Plowman, S. A., & Smith, D. L. (2003). Exercise physiology for health, fitness, and performance. Benjamin Cummings.
- Ross, R. (1999). Atherosclerosis: An inflammatory disease. The New England Journal of Medicine, 340(2), 115–126. https://doi.org/https://doi.org/10.1056/NEJM199901143400207
- Rowell, L. B. (1986). Human circulation: Regulation during physical stress. Oxford University Press.
- Simmons, G. H., Padilla, J., Young, C. N., Wong, B. J., Lang, J. A., Davis, M. J., Laughlin, M. H., & Fadel, P. J. (2011). Increased brachial artery retrograde shear rate at exercise onset is abolished during prolonged cycling: Role of thermoregulatory vasodilation. Journal of Applied Physiology, 110(2), 389–397. https://doi.org/https://doi.org/10.1152/japplphysiol.00936.2010
- Smith, J. R., Ade, C. J., Broxterman, R. M., Skutnik, B. C., Barstow, T. J., Wong, B. J., & Harms, C. A. (2014). Influence of exercise intensity on respiratory muscle fatigue and brachial artery blood flow during cycling exercise. European Journal of Applied Physiology, 114(8), 1767–1777. https://doi.org/https://doi.org/10.1007/s00421-014-2905-y
- Smolander, J., Saalo, J., & Korhonen, O. (1991). Effect of work load on cutaneous vascular response to exercise. Journal of Applied Physiology, 71(4), 1614–1619. https://doi.org/https://doi.org/10.1152/jappl.1991.71.4.1614
- Takahashi, N., Nakamura, T., Kanno, N., Kimura, K., Toge, Y., Lee, K. H., & Tajima, F. (2011). Local heat application to the leg reduces muscle sympathetic nerve activity in human. European Journal of Applied Physiology, 111(9), 2203–2211. https://doi.org/https://doi.org/10.1007/s00421-011-1852-0
- Tanaka, H., Shimizu, S., Ohmori, F., Muraoka, Y., Kumagai, M., Yoshizawa, M., & Kagaya, A. (2006). Increases in blood flow and shear stress to nonworking limbs during incremental exercise. Medicine and Science in Sports and Exercise, 38(1), 81–85. https://doi.org/https://doi.org/10.1249/01.mss.0000191166.81789.de
- Thijssen, D. H., Atkinson, C. L., Ono, K., Sprung, V. S., Spence, A. L., Pugh, C. J., & Green, D. J. (2014). Sympathetic nervous system activation, arterial shear rate, and flow-mediated dilation. Journal of Applied Physiology, 116(10), 1300–1307. https://doi.org/https://doi.org/10.1152/japplphysiol.00110.2014
- Thijssen, D. H., Dawson, E. A., Tinken, T. M., Cable, N. T., & Green, D. J. (2009). Retrograde flow and shear rate acutely impair endothelial function in humans. Hypertension, 53(6), 986–992. https://doi.org/https://doi.org/10.1161/HYPERTENSIONAHA.109.131508
- Tinken, T. M., Thijssen, D. H., Hopkins, N., Black, M. A., Dawson, E. A., Minson, C. T., Newcomer, S. C., Laughlin, M. H., Cable, N. T., & Green, D. J. (2009). Impact of shear rate modulation on vascular function in humans. Hypertension., 54(2), 278–285. https://doi.org/https://doi.org/10.1161/HYPERTENSIONAHA.109.134361
- Tinken, T. M., Thijssen, D. H., Hopkins, N., Dawson, E. A., Cable, N. T., & Green, D. J. (2010). Shear stress mediates endothelial adaptations to exercise training in humans. Hypertension, 55(2), 312–318. https://doi.org/https://doi.org/10.1161/HYPERTENSIONAHA.109.146282
- Wenger, C. B., Roberts, M. F., Stolwijk, J. A., & Nadel, E. R. (1975). Forearm blood flow during body temperature transients produced by leg exercise. Journal of Applied Physiology, 38(1), 58–63. https://doi.org/https://doi.org/10.1152/jappl.1975.38.1.58
- Woodman, C. R., Price, E. M., & Laughlin, M. H. (2005). Shear stress induces eNOS mRNA expression and improves endothelium-dependent dilation in senescent soleus muscle feed arteries. Journal of Applied Physiology, 98(3), 940–946. https://doi.org/https://doi.org/10.1152/japplphysiol.00408.2004
- Yamazaki, F., & Sone, R. (2006). Different vascular responses in glabrous and nonglabrous skin with increasing core temperature during exercise. European Journal of Applied Physiology, 97(5), 582–590. https://doi.org/https://doi.org/10.1007/s00421-006-0219-4