Airborne Allergens, Endotoxins, and Particulate Matter in Elementary Schools, Results from Germany (LUPE 2)

REFERENCES

• von Mutius , E. 2010 . Prevalence and determinants of asthma . Monatsschr. Kinderheilkd. , 158 : 121 – 128 . [in German]
   Web of Science ®Google Scholar
• Lau , S. , Illi , S. Sommerfeld , C. 2000 . Early exposure to house-dust mite and cat allergens and development of childhood asthma: A cohort study. Multicentre Allergy Study Group . Lancet , 356 : 1392 – 1397 .
   PubMed Web of Science ®Google Scholar
• Smedje , G. and Norback , D. 2001 . Incidence of asthma diagnosis and self-reported allergy in relation to the school environment—A four-year follow-up study in schoolchildren . Int. J. Tuberc. Lung Dis. , 5 : 1059 – 1066 .
   PubMed Web of Science ®Google Scholar
• Almqvist , C. , Wickman , M. Perfetti , L. 2001 . Worsening of asthma in children allergic to cats, after indirect exposure to cat at school . Am. J. Respir. Crit. Care Med. , 163 : 694 – 698 .
   PubMed Web of Science ®Google Scholar
• Ritz , B. R. , Hoelscher , B. , Frye , C. , Meyer , I. and Heinrich , J. 2002 . Allergic sensitization owing to “second-hand” cat exposure in schools . Allergy , 57 : 357 – 361 .
   PubMed Web of Science ®Google Scholar
• Kim , J. L. , Elfman , L. and Norbäck , D. 2007 . Respiratory symptoms, asthma and allergen levels in schools—Comparison between Korea and Sweden . Indoor Air , 17 : 122 – 129 .
   PubMed Web of Science ®Google Scholar
• Illi , S. , von Mutius , E. , Lau , S. , Niggemann , B. , Grüber , C. and Wahn , U. 2006 . Multicentre Allergy Study (MAS) group. Perennial allergen sensitisation early in life and chronic asthma in children: A birth cohort study . Lancet , 368 : 763 – 770 .
   PubMed Web of Science ®Google Scholar
• Platts-Mills , T. A. , Erwin , E. A. , Woodfolk , J. A. and Heymann , P. W. 2006 . Environmental factors influencing allergy and asthma . Chem. Immunol. Allergy , 91 : 3 – 15 .
   PubMedGoogle Scholar
• Celedón , J. C. , Milton , D. K. Ramsey , C. D. 2007 . Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood . J. Allergy Clin. Immunol. , 120 : 144 – 149 .
   PubMed Web of Science ®Google Scholar
• Arshad , S. H. 2010 . Does exposure to indoor allergens contribute to the development of asthma and allergy? . Curr. Allergy Asthma Rep. , 10 : 49 – 55 .
   PubMed Web of Science ®Google Scholar
• Chen , C. M. , Tischer , C. , Schnappinger , M. and Heinrich , J. 2010 . The role of cats and dogs in asthma and allergy—A systematic review . Int. J. Hyg. Environ. Health , 213 : 1 – 31 .
   PubMed Web of Science ®Google Scholar
• Berge , M. , Munir , A. K. and Dreborg , S. 1998 . Concentrations of cat (Fel d1), dog (Can f1) and mite (Der f1 and Der p1) allergens in the clothing and school environment of Swedish schoolchildren with and without pets at home . Pediatr. Allergy Immunol. , 9 : 25 – 30 .
   PubMed Web of Science ®Google Scholar
• Almqvist , C. , Larsson , P. H. , Egmar , A. C. , Hedren , M. , Malmberg , P. and Wickman , M. 1999 . School as a risk environment for children allergic to cats and a site for transfer of cat allergen to homes . J. Allergy Clin. Immunol. , 103 : 1012 – 1017 .
   PubMed Web of Science ®Google Scholar
• Instanes , C. , Hetland , G. , Berntsen , S. , Lovik , M. and Nafstad , P. 2005 . Allergens and endotoxin in settled dust from day-care centers and schools in Oslo, Norway . Indoor Air , 15 : 356 – 362 .
   PubMed Web of Science ®Google Scholar
• Patchett , K. , Lewis , S. , Crane , J. and Fitzharris , P. 1997 . Cat allergen (Fel d 1) levels on school children's clothing and in primary school classrooms in Wellington, New Zealand . J. Allergy Clin. Immunol. , 100 : 755 – 759 .
   PubMed Web of Science ®Google Scholar
• Antens , C. J.M. , Oldenwening , M. Wolse , A. 2006 . Repeated measurements of mite and pet allergen levels in house dust over a time period of 8 years . Clin. Exp. Allergy , 36 : 1525 – 1531 .
   PubMed Web of Science ®Google Scholar
• Swanson , M. , Campbell , A. , Klauck , M. and Reed , C. 1998 . Correlations between levels of mite and cat allergens in settled and airborne dust . J. Allergy Clin. Immunol. , 83 : 776 – 783 .
   Web of Science ®Google Scholar
• Bollinger , M. E. , Eggleston , P. A. , Flanagan , E. and Wood , R. A. 1996 . Cat antigen in homes with and without cats may induce allergic symptoms . J. Allergy Clin. Immunol. , 97 : 907 – 914 .
   PubMed Web of Science ®Google Scholar
• Custovic , A. , Simpson , B. , Simpson , A. , Hallam , C. and Woodcock , A. 1999 . Relationship between mite, cat, and dog allergens in reservoir dust and ambient air . Allergy , 54 : 612 – 616 .
   PubMed Web of Science ®Google Scholar
• Wickman , M. , Egmar , A.-C. Emenius , G. 1999 . Fel d 1 and Can f 1 in settled dust and airborne Fel d 1 in allergen avoidance day-care centers for atopic children in relation to number of pet-owners, ventilation, and general cleaning . Clin. Exp. Allergy , 29 : 626 – 632 .
   PubMed Web of Science ®Google Scholar
• Munir , A. K. , Einarsson , R. and Dreborg , S. 2003 . Variability of airborne cat allergen, Fel d1, in a public place . Indoor Air , 13 : 353 – 358 .
   PubMed Web of Science ®Google Scholar
• Raja , S. , Xu , Y. , Ferro , A. R. , Jaques , P. A. and Hopke , P. K. 2010 . Resuspension of indoor aeroallergens and relationship to lung inflammation in asthmatic children . Environ. Int. , 36 : 8 – 14 .
   PubMed Web of Science ®Google Scholar
• Wood , R. A. , Laheri , A. N. and Eggleston , P. A. 1993 . The aerodynamic characteristics of cat allergen . Clin. Exp. Allergy , 23 : 733 – 739 .
   PubMed Web of Science ®Google Scholar
• Custovic , A. , Simpson , A. , Pahdi , H. , Green , R. M. , Chapman , M. D. and Woodcock , A. 1998 . Distribution, aerodynamic characteristics, and removal of the major cat allergen Fel d 1 in British homes . Thorax , 53 : 33 – 38 .
   PubMed Web of Science ®Google Scholar
• Doreswamy , V. and Peden , D. B. 2010 . Modulation of asthma by endotoxin . Clin. Exp. Allergy , 41 : 9 – 19 .
   PubMed Web of Science ®Google Scholar
• Douwes , J. , van Strien , R. Doekes , G. 2006 . Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy Birth Cohort Study . J. Allergy Clin. Immunol. , 117 : 1067 – 1073 .
   PubMed Web of Science ®Google Scholar
• Gehring , U. , Strikwold , M. Schram-Bijker , D. 2008 . Asthma and allergic symptoms in relation to house dust endotoxin: Phase two of the International Study on Asthma and Allergies in Childhood (ISAAC II) . Clin. Exp. Allergy , 38 : 1911 – 1920 .
   PubMed Web of Science ®Google Scholar
• Erwin , E. A. , Wickens , K. Custis , N. J. 2005 . Cat and dust mite sensitivity and tolerance in relation to wheezing among children raised with high exposure to both allergens . J. Allergy Clin. Immunol. , 115 : 74 – 79 .
   PubMed Web of Science ®Google Scholar
• Eldridge , M. W. and Peden , D. B. 2000 . Airway response to concomitant exposure with endotoxin and allergen in atopic asthmatics . J. Toxicol. Environ. Health, Part A , 61 : 27 – 37 .
   PubMed Web of Science ®Google Scholar
• Fromme , H. , Dietrich , S. Twardella , D. 2007 . Particulate matter in the indoor air of classrooms—Exploratory results from Munich and surrounding area . Atmos. Environ. , 41 : 854 – 866 .
   Web of Science ®Google Scholar
• Fromme , H. , Heitmann , D. Dietrich , S. 2008 . Raumluftqualität in Schulen - Belastung von Klassenräumen mit Kohlendioxid (CO2), flüchtigen organischen Verbindungen (VOC), Aldehyden, Endotoxinen und Katzenallergenen . Gesundheitswesen , 70 : 88 – 97 . [in German]
   PubMed Web of Science ®Google Scholar
• Fahlbusch , B. , Jäger , L. , Koch , A. , Heinrich , J. and Burge , H. 1995 . Measurement and analysis of indoor allergens . Allergologie , 18 : 495 – 500 . [in German]
   Web of Science ®Google Scholar
• BIA-Arbeitsmappe (Berufsgenossenschaftliches Institut für Arbeitssicherheit - BIA) . 2002 . Verfahren zur Bestimmung der Endotoxinkonzentrationen , Sankt Augustin, Germany: Erich Schmidt Verlag . [in German]
   Google Scholar
• American Society of Heating, Refrigerating, and Air Conditioning Engineers, Inc. (ASHRAE) . 2001 . Ventilation for Acceptable Indoor Air Quality [Standard 62] , Atlanta , GA : ASHRAE .
   Google Scholar
• German Working Group on Indoor Guideline Values . 2008 . Health evaluation of carbon dioxide in indoor air . Bundesgesundheitsbl - Gesundheitsforsch - Gesundheitsschutz , 51 : 1358 – 1369 . [in German]
   PubMed Web of Science ®Google Scholar
• Daisey , J. M. , Angell , W. J. and Apte , M. G. 2003 . Indoor air quality, ventilation and health symptoms in schools: An analysis of existing information . Indoor Air , 13 : 53 – 64 .
   PubMed Web of Science ®Google Scholar
• Godwin , C. and Batterman , S. 2007 . Indoor air quality in Michigan schools . Indoor Air , 17 : 109 – 121 .
   PubMed Web of Science ®Google Scholar
• Wallner , P. , Kundi , M. Moshammer , H. 2012 . Indoor air in schools and lung function of Austrian school children . J. Environ. Monit. , 14 : 1976 – 1982 .
   PubMed Web of Science ®Google Scholar
• De Giuli , V. , Da Pos , O. and De Carli , M. 2012 . Indoor environmental quality and pupil perception in Italian primary schools . Building Environ. , 56 : 335 – 345 .
   Web of Science ®Google Scholar
• Guo , H. , Morawska , L. , He , C. , Zhang , Y. L. , Ayoko , G. and Cao , M. 2010 . Characterization of particle number concentrations and PM2.5 in a school: Influence of outdoor air pollution on indoor air . Environ. Sci. Pollut. Res. Int. , 17 : 1268 – 1278 .
   PubMed Web of Science ®Google Scholar
• Arvanitis , A. , Kotzias , D. Kephalopoulos , S. 2010 . The INDEX-PM project: Health risks from exposure to indoor particulate matter . Fresenius Environ. Bull. , 19 : 2458 – 2471 .
   Web of Science ®Google Scholar
• Einarsson , R. , Abul , K. , Munir , M. , Sten , K. and Dreborg , G. 1995 . Allergens in school dust: II. Major mite (Der p 1, Der f 1) in dust from Swedish schools . J. Allergy Clin. Immunol. , 95 : 1049 – 1053 .
   PubMed Web of Science ®Google Scholar
• Perzanowski , M. S. , Ronmark , E. , Nold , B. , Lundback , B. and Platts-Mills , T. A. 1999 . Relevance of allergens from cats and dogs to asthma in the northernmost province of Sweden: Schools as a major site of exposure . J. Allergy Clin. Immunol. , 103 : 1018 – 1024 .
   PubMed Web of Science ®Google Scholar
• Foarde , K. and Berry , M. 2004 . Comparison of biocontaminant levels associated with hard vs. carpet floors in nonproblem schools: Results of a year-long study . J. Expo. Anal. Environ. Epidemiol. , 14, Suppl 1 : S41 – S48 .
   PubMedGoogle Scholar
• Ramachandran , G. , Adgate , L. J. Banerjee , S. 2005 . Indoor air quality in two urban elementary schools - Measurements of airborne fungi, carpet allergens, CO2, temperature, and relative humidity . J. Occup. Environ. Hyg. , 2 : 553 – 566 .
   PubMed Web of Science ®Google Scholar
• Abramson , S. L. , Turner-Henson , A. Anderson , L. 2006 . Allergens in school settings: Results of environmental assessments in 3 city school systems . J. Sch. Health , 76 : 246 – 249 .
   PubMed Web of Science ®Google Scholar
• Zhang , G. , Spickett , J. , Rumchev , K. , Lee , A. H. and Stick , S. 2006 . Indoor environmental quality in a “low allergen” school and three standard primary schools in Western Australia . Indoor Air , 16 : 74 – 78 .
   PubMed Web of Science ®Google Scholar
• Tranter , D. C. , Wobbema , A. T. , Norlien , K. and Dorschner , D. F. 2009 . Indoor allergens in Minnesota schools and child care centers . J. Occup. Environ. Hyg. , 6 : 582 – 591 .
   PubMed Web of Science ®Google Scholar
• Custovic , A. , Green , R. Taggart , S. C.O. 1996 . Domestic allergens in public places II: Dog (CAN f 1) and cockroach (Bla g 2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings . Clin. Exp. Allergy , 26 : 1246 – 1252 .
   PubMed Web of Science ®Google Scholar
• Karlsson , A. S. , Renström , A. , Hedrén , M. and Larsson , K. 2004 . Allergen avoidance does not alter airborne cat allergen levels in classrooms . Allergy , 59 : 661 – 667 .
   PubMed Web of Science ®Google Scholar
• Permaul , P. , Hoffman , E. Fu , C. 2012 . Allergens in urban schools and homes of children with asthma . Pediatric Allergy Immunol. , 23 : 543 – 549 .
   PubMed Web of Science ®Google Scholar
• Gomes , C. , Freihaut , J. and Bahnfleth , W. 2007 . Resuspension of allergen-containing particles under mechanical and aerodynamic disturbances from human walking . Atmos. Environ. , 41 : 5257 – 5270 .
   Web of Science ®Google Scholar
• Hopke , J. P. personal communication of additional results, 2011
   Google Scholar
• Spaan , S. , Heederik , D. J.J. , Thorne , P. S. and Wouters , I. M. 2007 . Optimization of airborne endotoxin exposure assessment: Effects of filter type, transport conditions, extraction solutions, and storage of samples and extracts . Appl. Environ. Microbiol. , 73 : 6134 – 6143 .
   PubMed Web of Science ®Google Scholar
• Carty , C. L. , Gehring , U. , Cyrys , J. , Bischof , W. and Heinrich , J. 2003 . Seasonal variability of endotoxin in ambient fine particulate matter . J. Environ. Monit. , 5 : 953 – 958 .
   PubMed Web of Science ®Google Scholar
• Kujundzic , E. , Hernandez , M. and Miller , S. L. 2006 . Particle size distributions and concentrations of airborne endotoxin using novel collection methods during the winter and summer seasons . Indoor Air , 16 : 216 – 226 .
   PubMed Web of Science ®Google Scholar
• Dutch Expert Committee on Occupational Safety (DECOS) . 2010 . Endotoxins. Health-based recommended occupational exposure limit , The Hague , , The Netherlands : DECOS .
   Google Scholar
• Rylander , R. 2002 . Endotoxin in the environment - Exposure and effects . J. Endotoxin Res. , 8 : 241 – 252 .
   PubMedGoogle Scholar