Vitamin C promotes the proliferation of human adipose-derived stem cells via p53-p21 pathway

REFERENCES

• Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 2001; 7:211-28; PMID:11304456; http://dx.doi.org/10.1089/107632701300062859
   PubMedGoogle Scholar
• Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002; 13:4279-95; PMID:12475952; http://dx.doi.org/10.1091/mbc.E02-02-0105
   PubMed Web of Science ®Google Scholar
• Kim JH, Jung M, Kim HS, Kim YM, Choi EH. Adipose-derived stem cells as a new therapeutic modality for ageing skin. Exp Dermatol 2011; 20:383-7; PMID:21355887; http://dx.doi.org/10.1111/j.1600-0625.2010.01221.x
   PubMed Web of Science ®Google Scholar
• Mizuno H, Tobita M, Uysal AC. Concise review: Adipose-derived stem cells as a novel tool for future regenerative medicine. Stem Cells 2012; 30:804-10; PMID:22415904; http://dx.doi.org/10.1002/stem.1076
   PubMed Web of Science ®Google Scholar
• Catalano E, Cochis A, Varoni E, Rimondini L, Carrassi A, Azzimonti B. Adipose-derived adult stem cells: available technologies for potential clinical regenerative applications in dentistry. Crit Rev Biomed Eng 2013; 41:483-93; PMID:24940661
   PubMedGoogle Scholar
• Goto Y, Noda Y, Mori T, Nakano M. Increased generation of reactive oxygen species in embryos cultured in vitro. Free Radic Biol Med 1993; 15:69-75; PMID:8359711; http://dx.doi.org/10.1016/0891-5849(93)90126-F
   PubMed Web of Science ®Google Scholar
• Cramer C, Freisinger E, Jones RK, Slakey DP, Dupin CL, Newsome ER, Alt EU, Izadpanah R. Persistent high glucose concentrations alter the regenerative potential of mesenchymal stem cells. Stem Cells Dev 2010; 19:1875-84; PMID:20380516; http://dx.doi.org/10.1089/scd.2010.0009
   PubMed Web of Science ®Google Scholar
• Park JY, Kim MJ, Kim YK, Woo JS. Ceramide induces apoptosis via caspase-dependent and caspase-independent pathways in mesenchymal stem cells derived from human adipose tissue. Arch Toxicol 2011; 85:1057-65; PMID:21259059; http://dx.doi.org/10.1007/s00204-011-0645-x
   PubMed Web of Science ®Google Scholar
• Harrison FE, May JM. Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2. Free Radic Biol Med 2009; 46:719-30; PMID:19162177; http://dx.doi.org/10.1016/j.freeradbiomed.2008.12.018
   PubMed Web of Science ®Google Scholar
• Hu J, Cheng D, Gao X, Bao J, Ma X, Wang H. Vitamin C enhances the in vitro development of porcine pre-implantation embryos by reducing oxidative stress. Reprod Domest Anim 2012; 47:873-9; PMID:22239270; http://dx.doi.org/10.1111/j.1439-0531.2011.01982.x
   PubMed Web of Science ®Google Scholar
• Shi Y. Histone lysine demethylases: Emerging roles in development, physiology and disease. Nat Rev Genet 2007; 8:829-33; PMID:17909537; http://dx.doi.org/10.1038/nrg2218
   PubMed Web of Science ®Google Scholar
• Nualart F, Salazar K, Oyarce K, Cisternas P, Jara N, Silva-Álvarez C, Pastor P, Martínez F, García A, García-Robles Mde L, et al. Typical and atypical stem cells in the brain, vitamin C effect and neuropathology. Biol Res 2012; 45:243-56; PMID:23283434; http://dx.doi.org/10.4067/S0716-97602012000300006
   PubMed Web of Science ®Google Scholar
• Esteban MA, Wang T, Qin B, Yang J, Qin D, Cai J, Li W. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 2010; 6:71-9; PMID:20036631; http://dx.doi.org/10.1016/j.stem.2009.12.001
   PubMed Web of Science ®Google Scholar
• Wang Y, Singh A, Xu P, Pindrus MA, Blasioli DJ, Kaplan DL. Expansion and osteogenic differentiation of bone marrow-derived mesenchymal stem cells on a vitamin C functionalized polymer. Biomaterials 2006; 27:3265-73; PMID:16494940; http://dx.doi.org/10.1016/j.biomaterials.2006.01.036
   PubMed Web of Science ®Google Scholar
• Yu G, Floyd ZE, Wu X, Halvorsen YD, Gimble JM. Isolation of human adipose-derived stem cells from lipoaspirates. Methods Mol Biol 2011; 702:17-27; PMID:21082391; http://dx.doi.org/10.1007/978-1-61737-960-4_2
   PubMedGoogle Scholar
• Gimble JM, Bunnell BA, Frazier T, Rowan B, Shah F, Thomas-Porch C, Wu X. Adipose-derived stromal/stem cells: a primer. Organogenesis 2013; 9:3-10; PMID:23538753; http://dx.doi.org/10.4161/org.24279
   PubMed Web of Science ®Google Scholar
• Zeng G, Lai K, Li J, Zou Y, Huang H, Liang J, Tang X, Wei J, Zhang P. A rapid and efficient method for primary culture of human adipose-derived stem cells. Organogenesis 2013; 9:287-95; PMID:24280895; http://dx.doi.org/10.4161/org.27153
   PubMed Web of Science ®Google Scholar
• Chepda T, Cadau M, Girin P, Frey J, Chamson A. Monitoring of ascorbate at a constant rate in cell culture: effect on cell growth. In Vitro Cell Dev Biol Anim 2011; 37:26-30; http://dx.doi.org/10.1290/1071-2690(2001)037%3c0026:MOAAAC%3e2.0.CO;2
   Google Scholar
• Osiecki M, Ghanavi P, Atkinson K, Nielsen LK, Doran MR. The ascorbic acid paradox. Biochem Biophys Res Commun 2010; 400:466-70; PMID:20732307; http://dx.doi.org/10.1016/j.bbrc.2010.08.052
   PubMed Web of Science ®Google Scholar
• Huang Y, Tang X, Xie W, Zhou Y, Li D, Zhou Y, Zhu J, Yuan T, Lai L, Pang D, et al. Vitamin C enhances in vitro and in vivo development of porcine somatic cell nuclear transfer embryos. Biochem Biophys Res Commun 2011; 411:397-401; PMID:21749856; http://dx.doi.org/10.1016/j.bbrc.2011.06.160
   PubMed Web of Science ®Google Scholar
• Gourguechon S, Savich JM, Wang CC. The multiple roles of cyclin E1 in controlling cell cycle progression and cellular morphology of Trypanosoma brucei. J Mol Biol 2007; 368:939-50; PMID:17376478; http://dx.doi.org/10.1016/j.jmb.2007.02.050
   PubMed Web of Science ®Google Scholar
• Nevzorova YA, Bangen JM, Hu W, Haas U, Weiskirchen R, Gassler N, Huss S, Tacke F, Sicinski P, Trautwein C, et al. Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice. Hepatology 2012; 56:1140-9; PMID:22454377; http://dx.doi.org/10.1002/hep.25736
   PubMed Web of Science ®Google Scholar
• Jayapal SR, Kaldis P. Cyclin E1 regulates hematopoietic stem cell quiescence. Cell Cycle 2013; 12:3588; PMID:24189528; http://dx.doi.org/10.4161/cc.26974
   PubMed Web of Science ®Google Scholar
• Wawryk-Gawda E, Chylińska-Wrzos P, Lis-Sochocka M, Chłapek K, Bulak K, Jędrych M, Jodłowska-Jędrych B. P53 protein in proliferation, repair and apoptosis of cells. Protoplasma 2014; 251:525-33; PMID:24043441; http://dx.doi.org/10.1007/s00709-013-0548-1
   PubMed Web of Science ®Google Scholar
• Armesilla-Diaz A, Elvira G, Silva A. p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells. Exp Cell Res 2009; 315:3598-610; PMID:19686735; http://dx.doi.org/10.1016/j.yexcr.2009.08.004
   PubMed Web of Science ®Google Scholar
• Esteban MA, Pei D. Vitamin C improves the quality of somatic cell reprogramming. Nat Genet 2012; 44:366-7; PMID:22456737; http://dx.doi.org/10.1038/ng.2222
   PubMed Web of Science ®Google Scholar
• Yi C, Wang Q, Wang L, Huang Y, Li L, Liu L, Zhou X, Xie G, Kang T, Wang H, et al. MiR-663, a microRNA targeting p21 (WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngealcarcinoma. Oncogene 2012; 31:4421-33; PMID:22249270; http://dx.doi.org/10.1038/onc.2011.629
   PubMed Web of Science ®Google Scholar
• Kim JH, Song SY, Park SG, Song SU, Xia Y, Sung JH. Primary involvement of NADPH oxidase 4 in hypoxia-induced generation of reactive oxygen species in adipose-derived stem cells. Stem Cells Dev 2012; 21:2212-21; PMID:22181007; http://dx.doi.org/10.1089/scd.2011.0561
   PubMed Web of Science ®Google Scholar
• Kim JH, Park SG, Song SY, Kim JK, Sung JH. Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2. Cell Death Dis 2013; 4:e588; PMID:23579275; http://dx.doi.org/10.1038/cddis.2013.117
   PubMed Web of Science ®Google Scholar
• Lee EY, Xia Y, Kim WS, Kim MH, Kim TH, Kim KJ, Park BS, Sung JH. Hypoxia-enhanced wound-healing function of adipose-derived stem cells: increase in stem cell proliferation and up-regulation of VEGF and bFGF. Wound Repair Regen 2009; 17:540-7; PMID:19614919; http://dx.doi.org/10.1111/j.1524-475X.2009.00499.x
   PubMed Web of Science ®Google Scholar
• Jee MK, Kim JH, Han YM, Jung SJ, Kang KS, Kim DW, Kang SK. DHP-derivative and low oxygen tension effectively induces human adipose stromal cell reprogramming. PLOS One 2010; 5:e9026; PMID:20161735; http://dx.doi.org/10.1371/journal.pone.0009026
   PubMedGoogle Scholar
• Song JS, Cho HH, Lee BJ, Bae YC, Jung JS. Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells. Stem Cells Dev 2011; 20:1529-37; PMID:21158569; http://dx.doi.org/10.1089/scd.2010.0364
   PubMed Web of Science ®Google Scholar