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Commentary

START: STructure-Assisted RNA Translation

ORCID Icon & ORCID Icon
Pages 1250-1253 | Received 17 Jul 2018, Accepted 16 Aug 2018, Published online: 19 Sep 2018

References

  • Leppek K, Das R, Barna M. Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them. Nat Rev Mol Cell Biol. 2018;19:158–174.
  • Parsyan A, Svitkin Y, Shahbazian D, et al. mRNA helicases: the tacticians of translational control. Nat Rev Mol Cell Biol. 2011;12:235–245.
  • Marintchev A. Roles of helicases in translation initiation: A mechanistic view. Biochim Biophys Acta Gene Regul Mech. 2013;1829:799–809.
  • Sharma D, Jankowsky E. The Ded1/DDX3 subfamily of DEAD-box RNA helicases. Crit Rev Biochem Mol Biol. 2014;49:343–360.
  • Guenther U-P, Weinberg DE, Zubradt MM, et al. The helicase Ded1p controls use of near-cognate translation initiation codons in 5′ UTRs. Nature. 2018;1:130–134.
  • Martin F, Ménétret JF, Simonetti A, et al. Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation. Nat Commun. 2016;7:12622.
  • Tabet R, Schaeffer L, Freyermuth F, et al. CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts. Nat Commun. 2018;9:152.
  • Jagodnik J, Chiaruttini C, Guillier M. Stem-loop structures within mRNA coding sequences activate translation initiation and mediate control by small regulatory RNAs. Mol Cell. 2017;68:158–170.e3.
  • Napthine S, Ling R, Finch LK, et al. Protein-directed ribosomal frameshifting temporally regulates gene expression. Nat Commun. 2017;8:15582.
  • Martin F, Barends S, Jaeger S, et al. Cap-assisted internal initiation of translation of histone H4. Mol Cell. 2011;41:197–209.
  • Ingolia NT, Ghaemmaghami S, Newman JRS, et al. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science. 2009;324:218–223.
  • Archer SK, Shirokikh NE, Beilharz TH, et al. Dynamics of ribosome scanning and recycling revealed by translation complex profiling. Nature. 2016;535:570–574.
  • Rouskin S, Zubradt M, Washietl S, et al. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature. 2014;505:701–705.
  • Spitale RC, Flynn RA, Zhang QC, et al. Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 2015;519:486–490.
  • Floor SN, Doudna JA. Tunable protein synthesis by transcript isoforms in human cells. Elife. 2016;5:e10921.

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