1,874
Views
38
CrossRef citations to date
0
Altmetric
Research Article

The cytotoxic effects of the organophosphates chlorpyrifos and diazinon differ from their immunomodulating effects

, , , &
Pages 136-145 | Received 06 Feb 2009, Accepted 29 Mar 2009, Published online: 10 Jul 2009

References

  • Alavanja, M. C., Dosemeci, M., Samanic, C., Lubin, J., Lynch, C. F., Knott, C., Barker, J., Hoppin, J. A., Sandler, D. P., Coble, J., Thomas, K., and Blair, A. 2004. Pesticides and lung cancer risk in the agricultural health study cohort. Am. J. Epidemiol. 160:876–885.
  • Albers, J. W., Berent, S., Garabrant, D. H., Giordani, B., Schweitzer, S. J., Garrison, R. P., and Richardson, R. J. 2004. The effects of occupational exposure to chlorpyrifos on the neurologic examination of central nervous system function: A prospective cohort study. J. Occup. Environ. Med. 46:367–378.
  • Bagchi, D., Bagchi, M., Hassoun, E. A., and Stohs, S. J. 1995. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 104:129–140.
  • Blair, A., Sandler, D., Thomas, K., Hoppin, J. A., Kamel, F., Coble, J., Lee, W. J., Rusiecki, J., Knott, C., Dosemeci, M., Lynch, C. F., Lubin, J., and Alavanja, M. 2005. Disease and injury among participants in the Agricultural Health Study. J. Agric. Safety Health 11:141–150.
  • Blakley, B. R., Yole, M. J., Brousseau, P., Boermans, H., and Fournier, M. 1999. Effect of chlorpyrifos on immune function in rats. Vet. Hum. Toxicol. 41:140–144.
  • Burns, C. J., Garabrant, D., Albers, J. W., Berent, S., Giordani, B., Haidar, S., Garrison, R., and Richardson, R. J. 2006. Chlorpyrifos exposure and biological monitoring among manufacturing workers. Occup. Environ. Med. 63:218–220.
  • Fenske, R. A., Lu, C., Barr, D., and Needham, L. 2002. Children’s exposure to chlorpyrifos and parathion in an agricultural community in central Washington State. Environ. Health Perspect. 110:549–553.
  • Giordano, G., Afsharinejad, Z., Guizzetti, M., Vitalone, A., Kavanagh, T. J., Costa, L. G. 2007. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicol. Appl. Pharmacol. 219:181–189.
  • Handy, R. D., Abd-El Samei, H. A., Bayomy, M. F., Mahran, A. M., Abdeen, A. M., and El-Elaimy, E. A. 2002. Chronic diazinon exposure: Pathologies of spleen, thymus, blood cells, and lymph nodes are modulated by dietary protein or lipid in the mouse. Toxicology 172:13–34.
  • Hore, P., Robson, M., Freeman, N., Zhang, J., Wartenberg, D., Ozkaynak, H., Tulve, N., Sheldon, L., Needham, L., Barr, D., and Lioy, P. J. 2005. Chlorpyrifos accumulation patterns for child-accessible surfaces and objects and urinary metabolite excretion by children for 2 weeks after crack-and-crevice application. Environ. Health Perspect. 113:211–219.
  • Karalliedde, L. D., Edwards, and P., Marrs, T. C. 2003. Variables influencing the toxic response to organophosphates in humans. Food Chem. Toxicol. 41: 1–13.
  • Mohammad, F. K., Al-Badrany, Y. M., and Al-Jobory, M. M. 2008. Acute toxicity and cholinesterase inhibition in chicks dosed orally with organophosphate insecticides. Arh. Hig. Rada. Toksikol. 59: 145–151.
  • Oostingh, G. J., Schmittner, M., Ehart, A. K., Tischler, U., and Duschl, A. 2008. A high-throughput screening method based on stably-transformed human cells was used to determine the immunotoxic effects of fluoranthene and other PAHs. Toxicol. In Vitro 22:1301–1310.
  • Pluth, J. M., Nicklas, J. A., O’Neill, J. P., and Albertini, R. J. 1996. Increased frequency of specific genomic deletions resulting from in vitro malathion exposure. Cancer Res. 56:2393–2399.
  • Pruett, S. B. 1992. Immunotoxicity of organophosphorous compounds. In: Organophosphates, Chemistry, Fate and Effects (Chambers, J. E., and Levi, P. E., Eds.), New York: Academic Press, pp. 123–149.
  • Ramesh, A., and Ravi, P. E. 2002. A rapid and sensitive analytical method for the quantification of residues of endosulfan in blood. J. Environ. Monit. 4:190–193.
  • Tirelli, V., Catone, T., Turco, L., Di Consiglio E., Testai, E., and De Angelis, I. 2006. Effects of the pesticide chlorpyrifos on an in vitro model of interstinal barrier. Toxicol In Vitro 21:308–313.
  • Whyatt, R. M., Barr, D. B., Camann, D. E., Kinney, P. L., Barr, J. R., Andrews, H. F., Hoepner, L. A., Garfinkel, R., Hazi, Y., Reyes, A., Ramirez, J., Cosme, Y., and Perera, F. P. 2003. Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newborns. Environ. Health Perspect. 111:749–756.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.