Pre-sleep protein supplementation after an acute bout of evening resistance exercise does not improve next day performance or recovery in resistance trained men

References

• Davies RW, Carson BP, Jakeman PM. The effect of whey protein supplementation on the temporal recovery of muscle function following resistance training: a systematic review and meta-analysis. Nutrients. 2018;10(2):221.
   PubMed Web of Science ®Google Scholar
• Moore DR, Robinson MJ, Fry JL, et al. Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men. Am J Clin Nutr. 2009;89(1):161–168.
   PubMed Web of Science ®Google Scholar
• Witard OC, Jackman SR, Breen L, et al. Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise. Am J Clin Nutr. 2014;99(1):86–95.
   PubMed Web of Science ®Google Scholar
• Hartman JW, Tang JE, Wilkinson SB, et al. Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am J Clin Nutr. 2007;86(2):373–381.
   PubMed Web of Science ®Google Scholar
• Tang JE, Moore DR, Kujbida GW, et al. Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol. 2009;107(3):987–992.
   PubMed Web of Science ®Google Scholar
• Wilkinson SB, Tarnopolsky MA, MacDonald MJ, et al. Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. Am J Clin Nutr. 2007;85(4):1031–1040.
   PubMed Web of Science ®Google Scholar
• Areta JL, Burke LM, Ross ML, et al. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. Journal of Physiology. 2013;591(9):2319–2331.
   PubMed Web of Science ®Google Scholar
• Trommelen J, van Loon LJC. Pre-sleep protein ingestion to improve the skeletal muscle adaptive response to exercise training. Nutrients. 2016;8(12):763.
   PubMed Web of Science ®Google Scholar
• Levenhagen DK, Gresham JD, Carlson MG, et al. Postexercise nutrient intake timing in humans is critical to recovery of leg glucose and protein homeostasis. Am J Physiol Endocrinol Metab. 2001;280. DOI:10.1152/ajpendo.2001.280.6.e982
   Web of Science ®Google Scholar
• Res PT, Groen B, Pennings B, et al. Protein ingestion before sleep improves postexercise overnight recovery. Med Sci Sports Exerc. 2012;44(8):1560–1569.
   PubMed Web of Science ®Google Scholar
• Groen BBL, Res PT, Pennings B, et al. Intragastric protein administration stimulates overnight muscle protein synthesis in elderly men. AJP: Endocrinology and Metabolism. 2012; 302: E52–60.
   PubMed Web of Science ®Google Scholar
• Snijders T, Trommelen J, Kouw IWK, et al. The impact of pre-sleep protein ingestion on the skeletal muscle adaptive response to exercise in humans: an update. Front Nutr. 2019;6:17.
   PubMed Web of Science ®Google Scholar
• Abbott W, Brett A, Cockburn E, et al. Presleep casein protein ingestion: acceleration of functional recovery in professional soccer players. Int J Sports Physiol Perform. 2019;14(3):385–391.
   PubMed Web of Science ®Google Scholar
• West DWD, Sawan SA, Mazzulla M, et al. Whey protein supplementation enhances whole body protein metabolism and performance recovery after resistance exercise: a double-blind crossover study. Nutrients. 2017;9(7):735.
   PubMed Web of Science ®Google Scholar
• Vangsoe MT, Joergensen MS, Heckmann LHL, et al. Effects of insect protein supplementation during resistance training on changes in muscle mass and strength in young men. Nutrients. 2018;10(3):335.
   PubMed Web of Science ®Google Scholar
• Holwerda AM, Overkamp M, Paulussen KJM, et al. Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men. J Nutr. 2018;148(11):1723–1732.
   PubMed Web of Science ®Google Scholar
• Larsen MS, Clausen D, Jørgensen AA, et al. Presleep protein supplementation does not improve recovery during consecutive days of intense endurance training: a randomized controlled trial. Int J Sport Nutr Exerc Metab. 2019;29(4):426–434.
   PubMed Web of Science ®Google Scholar
• Apweiler E, Wallace D, Stansfield S, et al. Pre-bed casein protein supplementation does not enhance acute functional recovery in physically active males and females when exercise is performed in the morning. Sports. 2018;7(1):5.
   Web of Science ®Google Scholar
• Ormsbee MJ, Gorman KA, Miller EA, et al. Nighttime feeding likely alters morning metabolism but not exercise performance in female athletes. Appl Physiol Nutr Metab. 2016;41(7):719–727.
   PubMed Web of Science ®Google Scholar
• Madzima TA, Melanson JT, Black JR, et al. Pre-sleep consumption of casein and whey protein: effects on morning metabolism and resistance exercise performance in active women. Nutrients. 2018;10(9):1273.
   PubMed Web of Science ®Google Scholar
• Koch AJ, Pereira R, Machado M. The creatine kinase response to resistance exercise. Journal of Musculoskeletal Neuronal Interactions. 2014;14(1):68–77. PMID: 24583542.
   PubMed Web of Science ®Google Scholar
• Brown WM, Davison GW, McClean CM, et al. A systematic review of the acute effects of exercise on immune and inflammatory indices in untrained adults. Sports Medicine Open. 2015;1(1):35.
   PubMedGoogle Scholar
• Jackson AS, Pollock ML. Generalized equations for predicting body density of men. Br J Nutr. 1978;40(3):497–504.
   PubMed Web of Science ®Google Scholar
• Baechle T, Earle R. Essentials of strength training and conditioning. 3rd ed. Champaign, IL: Human Kinetics; 2008.
   Google Scholar
• Warren GL, Lowe DA, Armstrong RB. Measurement tools used in the study of eccentric contraction-induced injury. Sports Med. 1999;27(1):43–59.
   PubMed Web of Science ®Google Scholar
• Baird MF, Graham SM, Baker JS, et al. Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery. J Nutr Metab. 2012;2012:1–13.
   Google Scholar
• Xia Z, Cholewa JM, Dardevet D, et al. Effects of oat protein supplementation on skeletal muscle damage, inflammation and performance recovery following downhill running in untrained collegiate men. Food Function. 2018;9(9):4720–4729.
   PubMed Web of Science ®Google Scholar
• Brown MA, Stevenson EJ, Howatson G. Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females. Appl Physiol Nutr Metab. 2018;43(4):324–330.
   PubMed Web of Science ®Google Scholar
• Burnley ECD, Olson AN, Sharp RL, et al. Impact of protein supplements on muscle recovery after exercise-induced muscle soreness. J Exerc Sci Fit. 2010;8(2):89–96.
   Web of Science ®Google Scholar
• Kim J, Kim J, Lee J. Effect of compression garments on delayed-onset muscle soreness and blood inflammatory markers after eccentric exercise: a randomized controlled trial. J Exerc Rehabil. 2017;13(5):541–545.
   PubMed Web of Science ®Google Scholar
• Pasiakos SM, Lieberman HR, McLellan TM. Effects of protein supplements on muscle damage, soreness and recovery of muscle function and physical performance: a systematic review. Sports Med. 2014;44(5):655–670.
   PubMed Web of Science ®Google Scholar
• Magal M, Dumke CL, Urbiztondo ZG, et al. Relationship between serum creatine kinase activity following exercise-induced muscle damage and muscle fibre composition. J Sports Sci. 2010;28(3):257–266.
   PubMed Web of Science ®Google Scholar
• Nosaka K, Clarkson PM. Changes in indicators of inflammation after eccentric exercise of the elbow flexors. Med Sci Sports Exerc. 1996;28(8):953–961.
   PubMed Web of Science ®Google Scholar
• Do Carmo FC, Pereira R, MacHado M. Variability in resistance exercise induced hyperCKemia. Isokinetics and Exercise Science. 2011;19(3):191–197.
   Web of Science ®Google Scholar
• Thompson HS, Scordilis SP, de Souza MJ. Serum creatine kinase activity varies with ovulatory status in regularly exercising, premenopausal women. Hormone Res. 2006;65(3):151–158.
   PubMedGoogle Scholar
• Malm C, Nyberg P, Engström M, et al. Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies. Journal of Physiology. 2000;529(1):243–262.
   PubMed Web of Science ®Google Scholar
• Cipryan L, Svagera Z, Vala R. IL-6 and CRP response to maximal exercise intervention. J Sports Med Phys Fitness. 2015;55:813–823.
   PubMed Web of Science ®Google Scholar
• Mendham AE, Donges CE, Liberts EA, et al. Effects of mode and intensity on the acute exercise-induced IL-6 and CRP responses in a sedentary, overweight population. Eur J Appl Physiol. 2011;111(6):1035–1045.
   PubMed Web of Science ®Google Scholar
• Isaacs AW, Macaluso F, Smith C, et al. C-reactive protein is elevated only in high creatine kinase responders to muscle damaging exercise. Front Physiol. 2019;10. DOI:10.3389/fphys.2019.00086.
   PubMed Web of Science ®Google Scholar
• Semple SJ, Smith LL, McKune AJ, et al. Serum concentrations of C reactive protein, α1 antitrypsin, and complement (C3, C4, C1 esterase inhibitor) before and during the Vuelta a Espańa. Br J Sports Med. 2006;40(2):124–127.
   PubMed Web of Science ®Google Scholar
• Kinsey AW, Cappadona SR, Panton LB, et al. The effect of casein protein prior to sleep on fat metabolism in obese men. Nutrients. 2016;8(8):452.
   PubMed Web of Science ®Google Scholar
• Kinsey AW, Eddy WR, Madzima TA, et al. Influence of night-time protein and carbohydrate intake on appetite and cardiometabolic risk in sedentary overweight and obese women. Br J Nutr. 2014;112(3):320–327.
   PubMed Web of Science ®Google Scholar
• Ormsbee MJ, Kinsey AW, Eddy WR, et al. The influence of nighttime feeding of carbohydrate or protein combined with exercise training on appetite and cardiometabolic risk in young obese women. Appl Physiol Nutr Metab. 2014;40(1):37–45.
   Web of Science ®Google Scholar
• Leyh SM, Willingham BD, Baur DA, et al. Pre-sleep protein in casein supplement or whole-food form has no impact on resting energy expenditure or hunger in women. Br J Nutr. 2018;120(9):988–994.
   PubMed Web of Science ®Google Scholar
• Madzima TA, Panton LB, Fretti SK, et al. Night-time consumption of protein or carbohydrate results in increased morning resting energy expenditure in active college-aged men. Br J Nutr. 2014;111(1):71–77.
   PubMed Web of Science ®Google Scholar
• Lay AHH, Crabtree DR, Campbell TG, et al. A bedtime milk snack does not impact RMR, substrate utilisation and appetite the following morning in mildly overweight males. Br J Nutr. 2018;119(12):1355–1365.
   PubMed Web of Science ®Google Scholar