Associations between Medication Assisted Therapy Services Delivery and Mortality in a National Cohort of Veterans with Posttraumatic Stress Disorder and Opioid Use Disorder

References

• Ahmed, S. & Stanciu, C. N. (2017). Addiction and suicide: An unmet public health crisis. American Journal of Psychiatry Residents' Journal, 12(12), 3–6. doi:10.1176/appi.ajp-rj.2017.121202
   Google Scholar
• Amato, L., Minozzi, S., Davoli, M. & Vecchi, S. (2011). Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence. Cochrane Database of Systematic Reviews, (10), CD004147. doi:10.1002/14651858.CD004147.pub4
   PubMed Web of Science ®Google Scholar
• Anestis, M. D., Tull, M. T., Bagge, C. L. & Gratz, K. L. (2012). The moderating role of distress tolerance in the relationship between posttraumatic stress disorder symptom clusters and suicidal behavior among trauma exposed substance users in residential treatment. Archives of Suicide Research, 16(3), 198–211. doi:10.1080/13811118.2012.695269
   PubMed Web of Science ®Google Scholar
• Brady, K. T., Killeen, T. K, Brewerton, T., Lucerini, S. (2000). Comorbidity of psychiatric disorders and posttraumatic stress disorder. Journal of Clinical Psychiatry, 61(Suppl 7), 22–32.
   PubMed Web of Science ®Google Scholar
• Carroll, K. M. & Weiss, R. D. (2017) The role of behavioral interventions in buprenorphine maintenance treatment: A review. The American Journal of Psychiatry, 174(8), 738–747. doi:10.1176/appi.ajp.2016.16070792
   PubMed Web of Science ®Google Scholar
• Conner, K. R., Bohnert, A. S., McCarthy, J. F., Valenstein, M., Bossarte, R., Ignacio, R.,… Ilgen, M. A. (2013) Mental disorder comorbidity and suicide among 2.96 million men receiving care in the Veterans Health Administration health system. Journal of Abnormal Psychology, 122(1), 256–263. doi:10.1037/a0030163
   PubMed Web of Science ®Google Scholar
• Danovitch, I. (2016). Post-traumatic stress disorder and opioid use disorder: A narrative review of conceptual models. Journal of Addictive Diseases, 35(3), 169–179. doi:10.1080/10550887.2016.1168212
   PubMed Web of Science ®Google Scholar
• Defense Manpower and Data Center, Sunnyvale, California; Joint, Department of Veterans Affairs (VA) and Department of Defense (DoD). (2017). Suicide data repository – National Death Index (NDI) extract. https://www.suicideoutreach.org/SDR
   Google Scholar
• Degenhardt, L., Bucello, C., Mathers, B., Briegleb, C., Ali, H., Hickman, M. & McLaren, J. (2011). Mortality among regular or dependent users of heroin and other opioids: A systematic review and meta-analysis of cohort studies. Addiction, 106(1), 32–51. doi:10.1111/j.1360-0443.2010.03140.x
   PubMed Web of Science ®Google Scholar
• Degenhardt, L., Randall, D., Hall, W., Law, M., Butler, T. & Burns, L. (2009). Mortality among clients of a state-wide opioid pharmacotherapy program over 20 years: Risk factors and lives saved. Drug and Alcohol Dependence, 105, 9–15. doi:10.1016/j.drugalcdep.2009.05.021
   PubMed Web of Science ®Google Scholar
• Dugosh, K., Abraham, A. J., Seymour, B., McLoyd, K., Chalk, M. & Festinger, D. (2016). A systematic review on the use of psychosocial interventions in conjunction with medications for the treatment of opioid addiction. Journal of Addiction Medicine, 10, 93–103. doi:10.1097/ADM.0000000000000193
   PubMed Web of Science ®Google Scholar
• Ecker, A. H. & Hundt, N. (2018). Posttraumatic stress disorder in opioid agonist therapy: A review. Psychological Trauma: Theory, Research, Practice, and Policy. 10(6), 636–642. doi:10.1037/tra0000312
   PubMed Web of Science ®Google Scholar
• Forehand, J. A., Peltzman, T., Westgate, C. L., Riblet, N. B., Watts, B. V. & Shiner, B. (2019). Causes of excess mortality in veterans treated for posttraumatic stress disorder. American Journal of Preventive Medicine, 57(2), 145–152. doi:10.1016/j.amepre.2019.03.014
   PubMed Web of Science ®Google Scholar
• Gradus, J. L., Qin, P., Lincoln, A. K., Miller, M., Lawler, E., Sorensen, H. T. & Lash, T. L. (2010). Posttraumatic stress disorder and completed suicide. American Journal of Epidemiology, 171(6), 721–727. doi:10.1093/aje/kwp456
   PubMed Web of Science ®Google Scholar
• Harris, A. H.S., Reeder, R. N., Ellerbe, L. & Bowe, T. (2010). Are VHA administrative location codes valid indicators of specialty substance use disorder treatment? Journal of Rehabilitation Research & Development, 47(8), 699–708. doi:10.1682/JRRD.2009.07.0106
   PubMedGoogle Scholar
• Hassan, A. N., LeFoll, B. L., Imtiaz, S. & Rehm, J. (2017). The effect of post-traumatic stress disorder on the risk of developing prescription opioid use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III. Drug and Alcohol Dependence, 179, 260–266. doi:10.1016/j.drugalcdep.2017.07.012
   PubMed Web of Science ®Google Scholar
• Hildebrand, A., Behrendt, S. & Hoyer, J. (2015). Treatment outcome in substance use disorder patients with and without comorbid posttraumatic stress disorder: A systematic review. Psychotherapy Research, 25(5), 565–582. doi:10.1080/10503307.2014.923125
   PubMed Web of Science ®Google Scholar
• Ma, J., Bao, Y. P., Wang, R. J., Meng-Fa, S., Mo-Xuan, L., Jin-Qiao, L., … Lu, L. (2019). Effects of medication-assisted treatment on mortality among opioids users: A systematic review and meta-analysis. Molecular Psychiatry, 24(12), 1868–1883. doi:10.1038/s41380-018-0094-5
   PubMed Web of Science ®Google Scholar
• Manhapra, A., Quinones, L. & Rosenheck, R. (2016). Characteristics of veterans receiving buprenorphine vs methadone for OUD nationally in the VHA. Drug and Alcohol Dependence, 160, 82–89. doi:10.1016/j.drugalcdep.2015.12.035
   PubMed Web of Science ®Google Scholar
• Mills, K. L., Teesson, M., Ross, J., Darke, S. & Shanahan, M. (2005). The costs and outcomes of treatment for opioid dependence associated with posttraumatic stress disorder. Psychiatric Services, 56(8), 940–945. doi:10.1176/appi.ps.56.8.940
   PubMed Web of Science ®Google Scholar
• Mills, K. L., Teesson, M., Ross, J. & Peters, L. (2006). Trauma, PTSD, and substance use disorders: Findings from the Australian National Survey of Mental Health and Well-being. The American Journal of Psychiatry, 163(4), 652–658. doi:10.1176/appi.ajp.163.4.652
   PubMed Web of Science ®Google Scholar
• Molero, Y., Zetterqvist, J., Binswanger, I. A., Hellner, C., Larsson, H. & Fazel, S. (2018). Medications for alcohol and opioid use disorders and risk of suicidal behavior, accidental overdoses, and crime. The American Journal of Psychiatry, 175(10), 970–978. doi:10.1176/appi.ajp.2018.17101112
   PubMed Web of Science ®Google Scholar
• National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division & Board on Health Sciences Policy. (2018). Medication-assisted treatment for opioid use disorder: proceedings of a workshop—in brief. Washington, DC: National Academies Press (US). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK534504/ doi:10.17226/25322
   Google Scholar
• National Institute on Drug Abuse. (2019). Principles of drug addiction treatment: A research-based guide (3rd ed.). Retrieved from https://www.drugabuse.gov/publications/principles-drug-addiction-treatment-research-based-guide-third-edition/frequently-asked-questions/how-long-does-drug-addiction-treatment.
   Google Scholar
• Rich, K.M., Bia J, Altice, F. L., & Feinberg J. (2018). Integrated models of care for individuals with opioid use disorders: how do we prevent HIV and HCV? Current HIV/AIDS Reports, 15(3), 266–275. doi:10.1007/s11904-018-0396-x
   PubMed Web of Science ®Google Scholar
• Rockett, I. R. H., Caine, E. D., Connery, H. S., D'Onofrio, G., Gunnell, D. J., Miller, T. R., … Jia, H. (2018). Discerning suicide in drug intoxication deaths: Paucity and primacy of suicide notes and psychiatric history. PLoS One, SAMHSA 13(1), e0190200. doi:10.1371/journal.pone.0190200
   PubMed Web of Science ®Google Scholar
• Seal, K. H., Maguen, S., Bertenthal, D., Batki, S. L., Striebel, J., Stein, M. B., … Neylan, T. C. (2016). Observational evidence for buprenorphine's impact on posttraumatic stress symptoms in veterans with chronic pain and opioid use disorder. Journal of Clinical Psychiatry, 77(9), 1182–1188. doi:10.4088/JCP.15m09893
   PubMed Web of Science ®Google Scholar
• Shiner, B., Leonard Westgate, C., Bernardy, N. C., Schnurr, P. P. & Watts, B. V. (2017). Trends in opioid use disorder diagnoses and medication treatment among veterans with posttraumatic stress disorder. Journal of Dual Diagnosis, 13(3), 201–212. doi:10.1080/15504263.2017.1325033
   PubMed Web of Science ®Google Scholar
• Shorter, D., Hsieh, J. & Kosten, T. R. (2015). Pharmacologic management of comorbid post-traumatic stress disorder and addictions. The American Journal on Addictions, 24(8), 705–712. doi:10.1111/ajad.12306
   PubMed Web of Science ®Google Scholar
• Sofuoglu, M., DeVito, E. E. & Carroll, K. M. (2019). Pharmacological and behavioral treatment of opioid use disorder. Psychiatric Research and Clinical Practice, 1(1), 4–15. doi:10.1176/appi.prcp.20180006
   Google Scholar
• Sordo, L., Barrio, G., Bravo, M. J., Indave, B. I., Degenhardt, L., Wiessing, L., … Pastor-Barriuso, R. (2017). Mortality risk during and after opioid substitution treatment: Systematic review and meta-analysis of cohort studies. British Medical Journal, 357, j1550. doi:10.1136/bmj.j1550
   PubMed Web of Science ®Google Scholar
• Substance Abuse and Mental Health Services Administration (SAMHSA). (2017). Key substance use and mental health indicators in the United States: Results from the 2016 National Survey on Drug Use and Health(HHS Publication No. SMA 17-5044, NSDUH Series H-52). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. Retrieved from https://www.samhsa.gov/data/
   Google Scholar
• Valentino, R. J. & Van Bockstaele, E. (2015). Endogenous opioids: The downside of opposing stress. Neurobiology of Stress, 1, 23–32. doi:10.1016/j.ynstr.2014.09.006
   PubMed Web of Science ®Google Scholar
• van der Kolk, B. A. (1994). The body keeps the score: Memory and the evolving psychobiology of posttraumatic stress. Harvard Review of Psychiatry, 1(5), 253–265. doi:10.3109/10673229409017088
   PubMed Web of Science ®Google Scholar
• Volkow, N. D. & Morales, M. (2015). The brain on drugs: From reward to addiction. Cell, 162, 712–725. doi:10.1016/j.cell.2015.07.046
   PubMed Web of Science ®Google Scholar
• Wasserman, C. & Ossiander, E. (2018). Department of Health Agency Standards for reporting data with small numbers. Retrieved from https://www.doh.wa.gov/Portals/1/Documents/1500/SmallNumbers.pdf.
   Google Scholar
• Weiss, N. H., Tull, M. T., Sullivan, T. P., Dixon-Gordon, K. L. & Gratz, K. L. (2015). Posttraumatic stress disorder and risky behaviors among trauma-exposed inpatients with substance dependence: The influence of negative and positive urgency. Drug and Alcohol Dependence, 155, 147–153. doi:10.1016/j.drugalcdep.2015.07.679
   PubMed Web of Science ®Google Scholar
• Wilcox, C. E., Pommy, J. M. & Adinoff, B. (2016). Neural circuitry of impaired emotion regulation in substance use disorders. The American Journal of Psychiatry, 173(4), 344–361. doi:10.1176/appi.ajp.2015.15060710
   PubMed Web of Science ®Google Scholar
• Wilkerson, R. G., Kim, H. K., Windsor, T. A. & Mareiniss, D. P. (2016). The opioid epidemic in the United States. Emergency Medicine Clinics of North America, 34(2), e1–e23. doi:10.1016/j.emc.2015.11.002
   PubMedGoogle Scholar
• Xu, J., Murphy, S. L., Kochanek, K. D., Bastian, B. & Arias, E. (2018). Deaths: Final data for 2016. National Vital Statistics Reports, 67(5), 1–74.
   Google Scholar