76
Views
2
CrossRef citations to date
0
Altmetric
Case Report

Paracrine Effects of Leydig Cell Nodular Hyperplasia, Two Case Reports: A Neglected Phenomenon

, , , , , , & show all
Pages 392-398 | Received 30 Mar 2016, Accepted 27 Jun 2016, Published online: 23 Aug 2016

References

  • Teilmann G, Pedersen CB, Jensen TK, Shakkebaek NE, Juul A. Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries. Pediatrics 2005;116(6):1323–1328.
  • Leung AC, SJ Kogan. Focal lobular spermatogenesis and pubertal acceleration associated with ipsilateral Leydig cell hyperplasia. Urology 2000;56(3):508–509.
  • Chemes HE, Pasqualini T, Rivarola MA, Bergada C. Is testosterone involved in the initiation of spermatogenesis in humans? A clinicopathological presentation and physiological considerations in four patients with Leydig cell tumours of the testis or secondary Leydig cell hyperplasia. Int J Androl. 1982;5(3):229–245.
  • O'Grady MJ, McGrath N, Quinn FM, Capra ML, McDermott MB, Murphy NP. Spermatogenesis in a prepubertal boy. J Pediatr. 2012;161(2):369-369 e1.
  • Kim I, Young RH, Scully RE. Leydig cell tumors of the testis. A clinicopathological analysis of 40 cases and review of the literature. Am J SurgPathol. 1985;9(3):177–192.
  • Steinberger E, Root A, Ficher M, Smith KD. The role of androgens in the initiation of spermatogenesis in man. J Clin Endocrinol Metab. 1973;37(5):746–751.
  • Petkovic V, Salemi S, Vassella E, Karamitopoulou-Diamantis E, Meinhardt UJ, Fluck CE, Mullis PE. Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Horm Res. 2007;67(2):89–95.
  • Polepalle SK, Shabaik A, Alagiri M. Leydig cell tumor in a child with spermatocyte maturation and no pseudoprecocious puberty. Urology 2003:62(3):551.
  • Schedewie HK, Reiter EO, Beltins IZ, Seyed S, Wooten VD, Jimenez JF, Aiman EJ, DeVane GW, Redman JF, Elders MJ. Testicular Leydig cell hyperplasia as a cause of familial sexual precocity. J Clin Endocrinol Metab. 1981:52(2):271–278.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.