Modified Rapid AChE Method (MRAM) for Hirschsprung Disease Diagnosis: A Journey from Meier-Ruge Until Now

References

• Stocker JT, Dehner P. Pediatric pathology, Philadelphia: Lippincott: 2011.
   Google Scholar
• Meier-Ruge W, Lutterbeck PM, Herzog B, Morger R, Moser R, Scharli A. Acetylcholinesterase activity in suction biopsies of the rectum in the diagnosis of Hirschsprung's disease. J Pediatr Surg. 1972;7:11–17.
   PubMed Web of Science ®Google Scholar
• Karnovsky MJ, Roots LA. “Direct-coloring” thiocholine method for cholinesterases. J Histochem Cytochem. 1964;12:219–221.
   PubMed Web of Science ®Google Scholar
• Dobbins WO, 3rd, Bill AH, Jr. Diagnosis of Hirschsprung's disease excluded by rectal suction biopsy. N Engl J Med. 1965;272:990–993.
   PubMed Web of Science ®Google Scholar
• Kobayashi H, O'Briain DS, Hirakawa H, Wang Y, Puri P. A rapid technique of acetylcholinesterase staining. Arch Pathol Lab Med. 1994;118:1127–1129.
   PubMed Web of Science ®Google Scholar
• Kapur RP. Can we stop looking? Immunohistochemistry and the diagnosis of Hirschsprung disease. Am J Clin Pathol. 2006;126:9–12.
   PubMed Web of Science ®Google Scholar
• Qualman SJ, Jaffe R, Bove KE, Monforte-Munoz H. Diagnosis of Hirschsprung disease using the rectal biopsy: multi-institutional survey. Pediatr Dev Pathol. 1999;2:588–596.
   PubMed Web of Science ®Google Scholar
• Moore SW, Johnson G. Acetylcholinesterase in Hirschsprung's disease. Pediatr Surg Int. 2005;21:255–263.
   PubMed Web of Science ®Google Scholar
• Huntley CC, Shaffner LD, Challa VR, Lyerly AD. Histochemical diagnosis of Hirschsprung disease. Pediatrics. 1982;69:755–761.
   PubMed Web of Science ®Google Scholar
• de Brito IA, Maksoud JG. Evolution with age of the acetylcholinesterase activity in rectal suction biopsy in Hirschsprung's disease. J Pediatr Surg. 1987;22:425–430.
   PubMed Web of Science ®Google Scholar
• Larsson LT, Malmfors G, Sundler F. Neuropeptide Y, calcitonin generelated peptide, and galanin in Hirschsprung's disease: an immunocytochemical study. J Pediatr Surg. 1988;23:342–345.
   PubMed Web of Science ®Google Scholar
• Robey SS, Kuhajda FP, Yardley JH. Immunoperoxidase stains of ganglion cells and abnormal mucosal nerve proliferations in Hirschsprung's disease. Hum Pathol. 1988;19:432–437.
   PubMed Web of Science ®Google Scholar
• Luider TM, van Dommenlen MW, Tibboel D, Meijers JH, Ten Kate FJ, Trojanowski JQ, Molenaar JC. Differences in phosphorylation state of neurofilament proteins in ganglionic and aganglionic bowel segments of children with Hirschsprung's disease. J Pediatr Surg. 1992;27:815–819.
   PubMed Web of Science ®Google Scholar
• Sams VR, Bobrow LG, Happerfield L, Keeling J. Evaluation of PGP9.5 in the diagnosis of Hirschsprung's disease. J Pathol. 1992;168:55–58.
   PubMed Web of Science ®Google Scholar
• Shen Z, Ekelund M, Sundler F. Immunocytochemical evidence for chromogranin A and B in neuronal elements in human gut. Regul Pept. 1994;51:229–236.
   PubMedGoogle Scholar
• Hamada Y, Bishop AE, Federici G, Rivosecchi M, Talbot IC, Polak JM. Increased neuropeptide Y-immunoreactive innervation of aganglionic bowel in Hirschsprung's disease. Virchows Arch A Pathol Anat Histopathol. 1987;411:369–377.
   PubMedGoogle Scholar
• Abu-Alfa AK, Kuan SF, West AB, Reyes-Mugica M. Cathepsin D in intestinal ganglion cells. A potential aid to diagnosis in suspected Hirschsprung's disease. Am J Surg Pathol. 1997;21:201–205.
   PubMed Web of Science ®Google Scholar
• Wester T, Olsson Y, Olsen L. Expression of bcl-2 in enteric neurons in normal human bowel and Hirschsprung disease. Arch Pathol Lab Med. 1999;123:1264–1268.
   PubMed Web of Science ®Google Scholar
• Yang S, Donner LR. Detection of ganglion cells in the colonic plexuses by immunostaining for neuron-specific marker NeuN: an aid for the diagnosis of Hirschsprung disease. Appl Immunohistochem Mol Morphol. 2002;10:218–220.
   PubMedGoogle Scholar
• Brewer KC, Mwizerva O, Goldstein AM. BMPRIA is a promising marker for evaluating ganglion cells in the enteric nervous system—a pilot study. Hum Pathol. 2005;36:1120–1126.
   PubMed Web of Science ®Google Scholar
• Karim S, Hession C, Marconi S, Gang DL, Otis CN. The identification of ganglion cells in Hirschsprung disease by the immunohistochemical detection of ret oncoprotein. Am J Clin Pathol. 2006;126:49–54.
   PubMed Web of Science ®Google Scholar
• Canil M, Meir K, Sturby T, Moerike S, Gomez A. Toluidine blue staining is superior to h&e staining for the identification of ganglion cells in frozen rectal biopsies. Histologic. 2007;XL:1–3.
   Google Scholar
• Staines WA, Bettolli M, De Carli C, Sweeney B, Krantis A, Rubin SZ. Fast evaluation of intraoperative biopsies for ganglia in Hirschsprung's disease. J Pediatr Surg. 2007;42:2067–2070.
   PubMed Web of Science ®Google Scholar
• Burtelow MA, Longacre TA. Utility of microtubule associated protein-2 (MAP-2) immunohistochemistry for identification of ganglion cells in paraffin-embedded rectal suction biopsies. Am J Surg Pathol. 2009;33:1025–1030.
   PubMed Web of Science ®Google Scholar
• Holland SK, Hessler RB, Reid-Nicholson MD, Ramalingam P, Lee JR. Utilization of peripherin and S-100 immunohistochemistry in the diagnosis of Hirschsprung disease. Mod Pathol. 2010;23:1173–1179.
   PubMed Web of Science ®Google Scholar
• Tsuto T, Okamura H, Fukui K, Obata-Tsuto HL, Terubayashi H, Yanagihara J, Iwai N, Majima S, Yanaihara N, Ibata Y. Immunohistochemical investigations of gut hormones in the colon of patients with Hirschsprung's disease. J Pediatr Surg. 1985;20:266–270.
   PubMed Web of Science ®Google Scholar
• Furness JB, Costa M. Citation-classic—Types of nerves in the enteric nervous-system. Cc/Life Sci. 1987:17–17.
   Google Scholar
• Kawana T, Nada O, Ikeda K, Goto S, Hirose R, Taguchi T, Kubota M, Toyohara T, Shono T. Distribution and localization of glial fibrillary acidic protein in colons affected by Hirschsprung's disease. J Pediatr Surg. 1989;24:448–452.
   PubMed Web of Science ®Google Scholar
• Larsson LT, Sundler F. Neuronal markers in Hirschsprung's disease with special reference to neuropeptides. Acta Histochem Suppl. 1990;38:115–125.
   PubMedGoogle Scholar
• Patt S, Stoltenburg-Didinger G. Immunohistochemische Untersuchungen mit Synaptophysin an Darmbiopsien bei Morbus Hirschsprung. Zentralbl. Pathol. 1992:325–330.
   PubMedGoogle Scholar
• Yamataka A, Miyano T, Urao M, Nishiye H. Hirschsprung's disease: Diagnosis using monoclonal antibody 171B5. J Pediatr Surg. 1992;27:820–822.
   PubMed Web of Science ®Google Scholar
• Tam PK, Owen G. An immunohistochemical study of neuronal icrotubule associated proteins in Hirschsprung's disease. Hum Pathol. 1993;24:424–431.
   PubMed Web of Science ®Google Scholar
• Kobayashi H, Hirakawa H, O'Briain DS, Puri P. Nerve growth factor receptor staining of suction biopsies in the diagnosis of Hirschsprung's disease. J Pediatr Surg. 1994;29:1224–1227.
   PubMed Web of Science ®Google Scholar
• O'Kelly TJ, Davies JR, Tam PK, Brading AF, Mortensen NJ. Abnormalities of nitric-oxide-producing neurons in Hirschsprung's disease: morphology and implications. J Pediatr Surg. 1994;29, 294–299; discussion:299–300.
   Web of Science ®Google Scholar
• Kakita Y, Oshiro K, O'Briain DS, Puri P. Selective demonstration of mural nerves in ganglionic and aganglionic colon by immunohistochemistry for glucose transporter-1: prominent extrinsic nerve pattern staining in Hirschsprung disease. Arch Pathol Lab Med. 2000;124:1314–1319.
   PubMed Web of Science ®Google Scholar
• Nirasawa Y, Ito Y, Fujiwara T, Seki N, Tanaka H, Akagawa K. Altered immunoreactivity of HPC-1/syntaxin 1A in proliferated nerve fibers in the human aganglionic colon of Hirschsprung's disease. J Mol Neurosci. 2001;16:13–19.
   PubMed Web of Science ®Google Scholar
• Barshack I, Fridman E, Goldberg I, Chowers Y, Kopolovic J. The loss of calretinin expression indicates aganglionosis in Hirschsprung's disease. J Clin Pathol. 2004;57:712–716.
   PubMed Web of Science ®Google Scholar
• Kapur RP, Reed RC, Finn LC, Patterson K, Johanson J, Rutledge JC. Calretinin immunohistochemistry versus acetylcholinesterase histochemistry in the evaluation of suction rectal biopsies for Hirschsprung Disease. Pediatr Dev Pathol. 2009;12:6–15.
   PubMed Web of Science ®Google Scholar