123
Views
0
CrossRef citations to date
0
Altmetric
Case Reports

Ewing Sarcoma Displaying Extensive Well Differentiated Neuroblastomatous Differentiation: A Case Report

ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 156-160 | Received 29 Mar 2022, Accepted 26 Apr 2022, Published online: 10 May 2022

References

  • Folpe AL, Goldblum JR, Rubin BP, Shehata BM, Liu W, Dei Tos AP, Weiss SW. Morphologic and immunophenotypic diversity in Ewing family tumors: a study of 66 genetically confirmed cases. Am J Surg Pathol. 2005;29(8):1025–33.
  • Ewing J. Classics in oncology: Diffuse endothelioma of bone. James Ewing. Proceedings of the New York Pathological Society, 1921;12:17. Clin OrthopRelat Res. 2006;450:25–7.
  • Aurias A, Rimbaut C, Buffe D, Dubousset J, Mazabraud A. Translocation of chromosome 22 in Ewing’s sarcoma. C R Seances Acad Sci III. 1983;296(23):1105–7.
  • Turc-Carel C. Chromosomal translocations in Ewing’s sarcoma. N Engl J Med. 1983;309:496–8.
  • Delattre O, Zucman J, Plougastel B, Desmaze C, Melot T, Peter M, Kovar H, Joubert I, de Jong P, Rouleau G. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature. 1992;359(6391):162–5. doi:10.1038/359162a0.
  • de Alava E, Lessnick SL, Stamenkovic I. Ewing Sarcoma. WHO classification of undifferentiated small round cell sarcomas of bone and soft tissue. In: WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours (WHO classification of tumours series), 5th ed., Vol. 3. Lyon, France: International Agency for Research on Cancer; 2020. p. 323.
  • Hasegawa T, Hirose T, Kudo E, Hizawa K, Yamawaki S, Ishii S. Atypical primitive neuroectodermal tumors. Comparative light and electron microscopic and immunohistochemical studies on peripheral neuroepitheliomas and Ewing’s sarcomas. Acta Pathol Jpn. 1991;41(6):444–54. doi:10.1111/j.1440-1827.1991.tb03211.x.
  • Salet MCW, Vogels R, Brons P, Schreuder B, Flucke U. Maturation toward neuronal tissue in a Ewing Sarcoma of bone after chemotherapy. Diagn Pathol. 2016;11(1):74.
  • Shawraba F, Hammoud H, Mrad Y, Saker Z, Fares Y, Harati H, Bahmad HF, Nabha S. Biomarkers in neuroblastoma: an insight into their potential diagnostic and prognostic utilities. Curr Treat Options Oncol. 2021;22(11):102.
  • Collini P, Mezzelani A, Modena P, Dagrada P, Tamborini E, Luksch R, Gronchi A, Navarria P, Sozzi G, Pilotti S. Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing Sarcoma of bone. Am J Surg Pathol. 2003;27:1161–6.
  • Maeda G, Masui F, Yokoyama R, Shimoda T, Matsuno Y, Mukai K, Ohtomo K, Beppu Y, Fukuma H. Ganglion cells in Ewing’s sarcoma following chemotherapy: a case report. Pathol Int. 1998;48(6):475–80. doi:10.1111/j.1440-1827.1998.tb03936.x.
  • Schmidt D, Harms D, Burdach S. Malignant peripheral neuroectodermal tumours of childhood and adolescence. Virchows Arch A Pathol Anat Histopathol. 1985;406(3):351–65. doi:10.1007/BF00704304.
  • Weissferdt A, Kalhor N, Moran CA. Ewing Sarcoma with extensive neural differentiation: a clinicopathologic, immunohistochemical, and molecular analysis of three cases. Am J Clin Pathol. 2015;143(5):659–64. doi:10.1309/AJCPFHFX07JFCRGU.
  • Hisaoka M, Hashimoto H, Murao T. Peripheral primitive neuroectodermal tumour with ganglioneuroma-like areas arising in the cauda equina. Virchows Arch. 1997;431(5):365–9. doi:10.1007/s004280050112.
  • Russell-Goldman E, Hornick JL, Qian X, Jo VY. NKX2.2 immunohistochemistry in the distinction of Ewing Sarcoma from cytomorphologic mimics: diagnostic utility and pitfalls. Cancer Cytopathol. 2018;126(11):942–9. doi:10.1002/cncy.22056.
  • Hung YP, Lee JP, Bellizzi AM, Hornick JL. PHOX2B reliably distinguishes neuroblastoma among small round blue cell tumours. Histopathology. 2017;71(5):786–94. doi:10.1111/his.13288.
  • Azizoglu M, Demirsoy U, Kulac I, Aktas S, Çorapcioglu F. EWSR1(22q12) translocation positive pediatric adrenal tumor with loss of 1p, 11q, and unbalanced gain of 17q: neuroblastoma or Ewing Sarcoma? Fetal Pediatr Pathol. 2021;40(6):717–22. doi:10.1080/15513815.2020.1745971.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.