80
Views
1
CrossRef citations to date
0
Altmetric
Research Article

A Multicenter Study of Clinicopathology and Immunohistochemical Distinction between Adult and Pediatric Large B-Cell Lymphoma

ORCID Icon, , ORCID Icon, , , , , , , , & show all
Pages 355-366 | Received 29 Jun 2022, Accepted 20 Jul 2022, Published online: 15 Sep 2022

References

  • Vaidya R, Witzig TE. Prognostic factors for diffuse large B-cell lymphoma in the R(X)CHOP era. Ann Oncol. 2014;25(11):2124–33. doi:10.1093/annonc/mdu109.
  • Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000;403(6769):503–11. doi:10.1038/35000501.
  • Choi WWL, Weisenburger DD, Greiner TC, Piris MA, Banham AH, Delabie J, Braziel RM, Geng H, Iqbal J, Lenz G, et al. A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy. Clin Cancer Res. 2009;15(17):5494–502.89055. doi:10.1158/1078-0432.CCR-09-0113.
  • Raetz E, Perkins S, Davenport V, Cairo MS. B large-cell lymphoma in children and adolescents. Cancer Treat Rev. 2003;29(2):91–8. doi:10.1016/S0305-7372(02)00108-1.
  • Burkhardt B, Zimmermann M, Oschlies I, Niggli F, Mann G, Parwaresch R, Riehm H, Schrappe M, Reiter A. The impact of age and gender on biology, clinical features and treatment outcome of non-Hodgkin lymphoma in childhood and adolescence. Br J Haematol. 2005;131(1):39–49. doi:10.1111/j.1365-2141.2005.05735.x.
  • Hasserjian R, Le Beau M, List A, Thiele J. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: International Agency for Research on Cancer; 2017. p. 98.
  • National Comprehensive Cancer Network. B-Cell Lymphomas (Version 4.2022) [2022 June 9]. Available from: https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf
  • Chuang W-Y, Chang H, Chang G-J, Wang T-H, Chang Y-S, Wang T-H, Yeh C-J, Ueng S-H, Chien H-P, Chang C-Y, et al. Pleomorphic mantle cell lymphoma morphologically mimicking diffuse large B cell lymphoma: common cyclin D1 negativity and a simple immunohistochemical algorithm to avoid the diagnostic pitfall. Histopathology. 2017;70(6):986–99. Epub 20170310. doi:10.1111/his.13161.
  • Hans CP, Weisenburger DD, Greiner TC, Gascoyne RD, Delabie J, Ott G, et al. Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood. 2004;103(1):275–82. doi:10.1182/blood-2003-05-1545.
  • Lu T-X, Miao Y, Wu J-Z, Gong Q-X, Liang J-H, Wang Z, Wang L, Fan L, Hua D, Chen Y-Y, et al. The distinct clinical features and prognosis of the CD10(+)MUM1(+) and CD10(-)Bcl6(-)MUM1(-) diffuse large B-cell lymphoma. Sci Rep. 2016;6:20465. doi:10.1038/srep20465.
  • Meyer PN, Fu K, Greiner TC, Smith LM, Delabie J, Gascoyne RD, Ott G, Rosenwald A, Braziel RM, Campo E, et al. Immunohistochemical methods for predicting cell of origin and survival in patients with diffuse large B-cell lymphoma treated with rituximab. J Clin Oncol. 2011;29(2):200–7. doi:10.1200/JCO.2010.30.0368.
  • Costa LJ, Feldman AL, Micallef IN, Inwards DJ, Johnston PB, Porrata LF, Ansell SM. Germinal center B (GCB) and non-GCB cell-like diffuse large B cell lymphomas have similar outcomes following autologous haematopoietic stem cell transplantation. Br J Haematol. 2008;142(3):404–12. doi:10.1111/j.1365-2141.2008.07207.x.
  • Muris JJF, Meijer CJLM, Vos W, van Krieken JHJM, Jiwa NM, Ossenkoppele GJ, Oudejans JJ. Immunohistochemical profiling based on Bcl-2, CD10 and MUM1 expression improves risk stratification in patients with primary nodal diffuse large B cell lymphoma. J Pathol. 2006;208(5):714–23. doi:10.1002/path.1924.
  • Seki R, Ohshima K, Fujisaki T, Uike N, Kawano F, Gondo H, Makino S, Eto T, Moriuchi Y, Taguchi F, et al. Prognostic impact of immunohistochemical biomarkers in diffuse large B-cell lymphoma in the rituximab era. Cancer Sci. 2009;100(10):1842–7. doi:10.1111/j.1349-7006.2009.01268.x.
  • Chang S-T, Chen S-W, Ho C-H, Kuo C-C, Sakata S, Takeuchi K, Chuang S-S. Immunophenotypic and genetic characteristics of diffuse large B-cell lymphoma in Taiwan. J Formos Med Assoc. 2016;115(11):961–7. doi:10.1016/j.jfma.2016.09.006.
  • Yoon SO, Jeon YK, Paik JH, Kim WY, Kim YA, Kim JE, Kim CW. MYC translocation and an increased copy number predict poor prognosis in adult diffuse large B-cell lymphoma (DLBCL), especially in germinal centre-like B cell (GCB) type. Histopathology. 2008;53(2):205–17. doi:10.1111/j.1365-2559.2008.03076.x.
  • Li T, Medeiros LJ, Lin P, Yin H, Littlejohn M, Im W, Lennon PA, Hu P, Jorgensen JL, Liang M, et al. Immunohistochemical profile and fluorescence in situ hybridization analysis of diffuse large B-cell lymphoma in northern China. Arch Pathol Lab Med. 2010;134(5):759–65. doi:10.1043/1543-2165-134.5.759.
  • Al-Abbadi MA, Hattab EM, Tarawneh MS, Amr SS, Orazi A, Ulbright TM. Primary testicular diffuse large B-cell lymphoma belongs to the nongerminal center B-cell-like subgroup: a study of 18 cases. Mod Pathol. 2006;19(12):1521–7. doi:10.1038/modpathol.3800691.
  • Camilleri-Broët S, Crinière E, Broët P, Delwail V, Mokhtari K, Moreau A, Kujas M, Raphaël M, Iraqi W, Sautès-Fridman C, et al. A uniform activated B-cell-like immunophenotype might explain the poor prognosis of primary central nervous system lymphomas: analysis of 83 cases. Blood. 2006;107(1):190–6. doi:10.1182/blood-2005-03-1024.
  • Murase T, Yamaguchi M, Suzuki R, Okamoto M, Sato Y, Tamaru J-i, Kojima M, Miura I, Mori N, Yoshino T, et al. Intravascular large B-cell lymphoma (IVLBCL): a clinicopathologic study of 96 cases with special reference to the immunophenotypic heterogeneity of CD5. Blood. 2007;109(2):478–85. doi:10.1182/blood-2006-01-021253.
  • Yoshida S, Nakamura N, Sasaki Y, Yoshida S, Yasuda M, Sagara H, Ohtake T, Takenoshita S, Abe M. Primary breast diffuse large B-cell lymphoma shows a non-germinal center B-cell phenotype. Mod Pathol. 2005;18(3):398–405. doi:10.1038/modpathol.3800266.
  • Miles RR, Raphael M, McCarthy K, Wotherspoon A, Lones MA, Terrier-Lacombe MJ, Patte C, Gerrard M, Auperin A, Sposto R, et al. Pediatric diffuse large B-cell lymphoma demonstrates a high proliferation index, frequent c-Myc protein expression, and a high incidence of germinal center subtype: Report of the French-American-British (FAB) international study group. Pediatr Blood Cancer. 2008;51(3):369–74. doi:10.1002/pbc.21619.
  • Oschlies I, Klapper W, Zimmermann M, Krams M, Wacker H-H, Burkhardt B, Harder L, Siebert R, Reiter A, Parwaresch R, et al. Diffuse large B-cell lymphoma in pediatric patients belongs predominantly to the germinal-center type B-cell lymphomas: a clinicopathologic analysis of cases included in the German BFM (Berlin-Frankfurt-Munster) multicenter trial. Blood. 2006;107(10):4047–52. doi:10.1182/blood-2005-10-4213.
  • Engelhard M, Brittinger G, Huhn D, Gerhartz HH, Meusers P, Siegert W, et al. Subclassification of diffuse large B-cell lymphomas according to the Kiel classification: distinction of centroblastic and immunoblastic lymphomas is a significant prognostic risk factor. Blood. 1997;89(7):2291–7. Epub 1997/04/01.
  • Song M-K, Chung J-S, Shin D-Y, Lim S-N, Lee G-W, Choi J-C, Park W-Y, Oh S-Y. Tumor necrosis could reflect advanced disease status in patients with diffuse large B cell ­lymphoma treated with R-CHOP therapy. Ann Hematol. 2017;96(1):17–23. doi:10.1007/s00277-016-2822-8.
  • Cairo M, Auperin A, Perkins SL, Pinkerton R, Harrison L, Goldman S, Patte C. Overall survival of children and adolescents with mature B cell non-Hodgkin lymphoma who had refractory or relapsed disease during or after treatment with FAB/LMB 96: a report from the FAB/LMB 96 study group. Br J Haematol. 2018;182(6):859–69. doi:10.1111/bjh.15491.
  • Patte C, Auperin A, Gerrard M, Michon J, Pinkerton R, Sposto R, Weston C, Raphael M, Perkins SL, McCarthy K, et al. Results of the randomized international FAB/LMB96 trial for intermediate risk B-cell non-Hodgkin lymphoma in children and adolescents: it is possible to reduce treatment for the early responding patients. Blood. 2007;109(7):2773–80. doi:10.1182/blood-2006-07-036673.
  • Frost M, Newell J, Lones MA, Tripp SR, Cairo MS, Perkins SL. Comparative immunohistochemical analysis of pediatric Burkitt lymphoma and diffuse large B-cell lymphoma. Am J Clin Pathol. 2004;121(3):384–92. doi:10.1309/8WYN-VUTG-V9RP-HUQH.
  • Bellan C, Stefano L, Giulia de F, Rogena EA, Lorenzo L. Burkitt lymphoma versus diffuse large B-cell lymphoma: a practical approach. Hematol Oncol. 2009;27(4):182–5. doi:10.1002/hon.914.
  • Poirel HA, Cairo MS, Heerema NA, Swansbury J, Aupérin A, Launay E, Sanger WG, Talley P, Perkins SL, Raphaël M, et al. Specific cytogenetic abnormalities are associated with a significantly inferior outcome in children and adolescents with mature B-cell non-Hodgkin’s lymphoma: results of the FAB/LMB 96 international study. Leukemia. 2009;23(2):323–31. doi:10.1038/leu.2008.312.
  • Akasaka T, Akasaka H, Ueda C, Yonetani N, Maesako Y, Shimizu A, Yamabe H, Fukuhara S, Uchiyama T, Ohno H, et al. Molecular and clinical features of non-Burkitt’s, diffuse large-cell lymphoma of B-cell type associated with the c-MYC/immunoglobulin heavy-chain fusion gene. J Clin Oncol. 2000;18(3):510–8. doi:10.1200/JCO.2000.18.3.510.
  • Kawasaki C, Ohshim K, Suzumiya J, Kanda M, Tsuchiya T, Tamura K, Kikuchi M. Rearrangements of bcl-1, bcl-2, bcl-6, and c-myc in diffuse large B-cell lymphomas. Leuk Lymphoma. 2001;42(5):1099–106. doi:10.3109/10428190109097730.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.