2,970
Views
28
CrossRef citations to date
0
Altmetric
Research Paper - Basic Science

Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes

, ORCID Icon, , , , , , , , , , , & ORCID Icon show all
Pages 825-844 | Received 04 Jan 2017, Accepted 04 Oct 2017, Published online: 10 Apr 2018

References

  • Schiattarella GG, Hill JA. Therapeutic targeting of autophagy in cardiovascular disease. J Molecular and Cellular Cardiology. 2016;95:86–93. doi:10.1016/j.yjmcc.2015.11.019. PMID:26602750
  • Nakayama H, Nishida K, Otsu K. Macromolecular degradation systems and cardiovascular aging. Circ Res. 2016;118(10):1577–1592. doi:10.1161/CIRCRESAHA.115.307495. PMID:27174951
  • Leon LJ, Gustafsson ÅB. Staying young at heart: autophagy and adaptation to cardiac aging. J Mol Cell Cardiol. 2016;95:78–85. doi:10.1016/j.yjmcc.2015.11.006. PMID:26549356
  • Vásquez‐Trincado C, García‐Carvajal I, Pennanen C, Parra V, Hill JA, Rothermel BA, Lavandero S. Mitochondrial dynamics, mitophagy and cardiovascular disease. J Physiol. 2016;594(3):509–525. doi:10.1113/JP271301. PMID:26537557
  • Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. Dynamics and diversity in autophagy K151chanisms: lessons from yeast. Nat Rev Mol Cell Biol. 2009;10(7):458–467. doi:10.1038/nrm2708. PMID:19491929
  • Fujita N, Morita E, Itoh T, Tanaka A, Nakaoka M, Osada Y, Umemoto T, Saitoh T, Nakatogawa H, Kobayashi S, et al. Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol. 2013;203(1):115–128. doi:10.1083/jcb.201304188. PMID:24100292
  • Kaufmann A, Beier V, Franquelim HG, Wollert T. Molecular mechanism of autophagic membrane-scaffold assembly and disassembly. Cell. 2014;156(3):469–481. doi:10.1016/j.cell.2013.12.022. PMID:24485455
  • Reggiori F, Klionsky DJ. Autophagosomes: biogenesis from scratch? Curr Opin Cell Biol. 2005;17(4):415–422. doi:10.1016/j.ceb.2005.06.007. PMID:15978794
  • Cebollero E, Reggiori F. Regulation of autophagy in yeast Saccharomyces cerevisiae. Biochim Biophys Acta (BBA)-Mol Cell Res. 2009;1793(9):1413–1421. doi:10.1016/j.bbamcr.2009.01.008.
  • Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol. 2013;15(7):713–720. doi:10.1038/ncb2788. PMID:23817233
  • Song H, Pu J, Wang L, Xiao J, Liu Q, Chen J, Zhang M, Liu Y, Ni M, et al. ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation. Autophagy. 2015;11(8):1308–1325. doi:10.1080/15548627.2015.1060386. PMID:26083323
  • Biggar KK, Li SS-C. Non-histone protein methylation as a regulator of cellular signalling and function. Nat Rev Mol Cell Biol. 2015;16(1):5–17. doi:10.1038/nrm3915. PMID:25491103
  • Pierre CC, Longo J, Bassey-Archibong BI, Hallett RM, Milosavljevic S, Beatty L, Hassell JA, Daniel JM. Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso. Biochim Biophys Acta (BBA)-Gene Reg Mech. 2015;1849(12):1432–1441. doi:10.1016/j.bbagrm.2015.10.018.
  • Guedes-Dias P, de Proença J, Soares TR, Leitão-Rocha A, Pinho BR, Duchen MR, Oliveira JM. HDAC6 inhibition induces mitochondrial fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons. Biochim Biophys Acta (BBA)-Mol Basis Dis. 2015;1852(11):2484–2493. doi:10.1016/j.bbadis.2015.08.012.
  • Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2016;12(1):1–222. doi:10.1080/15548627.2015.1100356. PMID:26799652
  • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010;140(3):313–326. doi:10.1016/j.cell.2010.01.028. PMID:20144757
  • Kobayashi S, Volden P, Timm D, Mao K, Xu X, Liang Q. Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death. J Biol Chem. 2010;285(1):793–804. doi:10.1074/jbc.M109.070037. PMID:19901028
  • Kassner I, Andersson A, Fey M, Tomas M, Ferrando-May E, Hottiger MO. SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress. Open Biology. 2013;3(10):120173. doi:10.1098/rsob.120173. PMID:24088713
  • Ceballos-Chávez M, Rivero S, García-Gutiérrez P, Rodríguez-Paredes M, García-Domínguez M, Bhattacharya S, Reyes JC. Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex. Proc Natl Acad Sci. 2012;109(21):8085–8090. doi:10.1073/pnas.1121522109.
  • Nicholson TB, Chen T. LSD1 demethylates histone and non-histone proteins. Epigenetics. 2009;4(3):129–132. doi:10.4161/epi.4.3.8443. PMID:19395867
  • Barsyte-Lovejoy D, Li F, Oudhoff MJ, Dong A, Zeng H, Wu H, Freeman SA, Schapira M, Senisterra GA, et al. (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proc Natl Acad Sci. 2014;111(35):12853–12858. doi:10.1073/pnas.1407358111.
  • Popelka H, Klionsky DJ. Post‐translationally‐modified structures in the autophagy machinery: an integrative perspective. FEBS J. 2015;282(18):3474–3488. doi:10.1111/febs.13356. PMID:26108642
  • Wani WY, Boyer-Guittaut M, Dodson M, Chatham J, Darley-Usmar V, Zhang J. Regulation of autophagy by protein post-translational modification. Lab Invest. 2015;95(1):14–25. doi:10.1038/labinvest.2014.131. PMID:25365205
  • Mao K, Klionsky DJ. AMPK activates autophagy by phosphorylating ULK1. Circ Res. 2011;108(7):787–788. doi:10.1161/RES.0b013e3182194c29. PMID:21454792
  • Xu D, Shan B, Sun H, Xiao J, Zhu K, Xie X, Li X, Liang W, Lu X, Qian L, et al. USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1. Genes & Development. 2016;30(15):1718–1730. doi:10.1101/gad.285122.116.
  • Shi C-S, Kehrl JH. Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1. Autophagy. 2010;6(7):986–987. doi:10.4161/auto.6.7.13288. PMID:20798608
  • Lee IH, Finkel T. Regulation of autophagy by the p300 acetyltransferase. J Biol Chem. 2009;284(10):6322–6328. doi:10.1074/jbc.M807135200. PMID:19124466
  • Xie Q, Hao Y, Tao L, Peng S, Rao C, Chen H, You H, Dong M-q, Yuan Z. Lysine methylation of FOXO3 regulates oxidative stress‐induced neuronal cell death. EMBO Rep. 2012;13(4):371–377. doi:10.1038/embor.2012.25. PMID:22402663
  • Feng S, Jin Y, Cui M, Zheng J. Lysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells. Med Sci Monit: Int Med J Exp Clinical Res. 2016;22:4742. doi:10.12659/MSM.898825. PMID:27914215
  • Periz G, Lu J, Zhang T, Jablonski AM, Kalb R, McCampbell A, Wang J. Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription. PLoS Biol. 2015;13(4):e1002114. doi:10.1371/journal.pbio.1002114. PMID:25837623
  • Xie Y, Kang R, Sun X, Zhong M, Huang J, Klionsky DJ, Tang D. Posttranslational modification of autophagy-related proteins in macroautophagy. Autophagy. 2015;11(1):28–45. doi:10.4161/15548627.2014.984267. PMID:25484070
  • Lezina L, Aksenova V, Ivanova T, Purmessur N, Antonov A, Tentler D, Fedorova O, Garabadgiu AV, Talianidis I, Melino G, et al. KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stress. Cell Death & Differentiation. 2014;21(12):1889–1899. doi:10.1038/cdd.2014.108.
  • Shen C, Wang D, Liu X, Gu B, Du Y, Wei F-Z, Cao L-L, Song B., Lu X, Yang Q, et al. SET7/9 regulates cancer cell proliferation by influencing β-catenin stability. FASEB J. 2015;29(10):4313–4323. doi:10.1096/fj.15-273540. PMID:26116705
  • Zhao L, Zhang Y, Gao Y, Geng P, Lu Y, Liu X, Yao. R, Hou P, Liu D, Lu J, et al. JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein. Cell Death & Differentiation. 2015;22(10):1630–1640. doi:10.1038/cdd.2015.6.
  • Suzuki S, Nozawa Y, Tsukamoto S, Kaneko T, Imai H, Minami N. Histone methyltransferase Smyd3 regulates early embryonic lineage commitment in mice. Reproduction. 2015;150(1):21–30. doi:10.1530/REP-15-0019. PMID:25918436
  • Hadad I, Veithen A, Springael JY, Sotiropoulou PA, Da Costa AM, Miot F, Naeije R, De Deken X, Mc Entee K. Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes. PLoS One. 2013;8(2):e56007. doi:10.1371/journal.pone.0056007. PMID:23460790
  • Romanov J, Walczak M, Ibiricu I, Schüchner S, Ogris E, Kraft C, Martens S. Mechanism and functions of membrane binding by the Atg5–Atg12/Atg16 complex during autophagosome formation. EMBO J. 2012;31(22):4304–4317. doi:10.1038/emboj.2012.278. PMID:23064152
  • Shi Y, Lan F, Matson C, Whetstine JR, Cole PA, Casero RA, Shi Y. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell. 2004;119(7):941–953. doi:10.1016/j.cell.2004.12.012. PMID:15620353
  • Wan TC, Ge Z-D, Tampo A, Mio Y, Bienengraeber MW, Tracey WR, Gross GJ, Kwok WM, Auchampach JA. The A3 adenosine receptor agonist CP-532,903 [N6-(2, 5-dichlorobenzyl)-3′-aminoadenosine-5′-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel. J Pharmacol Exp Ther. 2008;324(1):234–243. doi:10.1124/jpet.107.127480. PMID:17906066
  • Gauthier T, Claude-Taupin A, Delage-Mourroux R, Boyer-Guittaut M, Hervouet E. Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction. PLoS One. 2015;10(6):e0128701. doi:10.1371/journal.pone.0128701. PMID:26034986

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.