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Editor’s Corner

Plasmodium protein UIS3 protects the parasite from autophagy clearance

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Pages 1291-1292 | Received 28 May 2018, Accepted 30 May 2018, Published online: 01 Aug 2018

References

  • Cowman AF, Healer J, Marapana D, et al. Malaria: biology and disease. Cell. 2016;167(3):610–624.
  • Graewe S, Rankin KE, Lehmann C, et al. Hostile takeover by Plasmodium: reorganization of parasite and host cell membranes during liver stage egress. PLoS Pathog. 2011;7(9):e1002224.
  • Real E, Rodrigues L, Cabal GG, et al. Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes. Nat Microbiol. 2018;3(1):17–25.
  • Spielmann T, Montagna GN, Hecht L, et al. Molecular make-up of the Plasmodium parasitophorous vacuolar membrane. Int J Med Microbiol. 2012;302(4–5):179–186.
  • Birgisdottir AB, Lamark T, Johansen T. The LIR motif - crucial for selective autophagy. J Cell Sci. 2013;126(Pt 15):3237–3247.

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