1,438
Views
0
CrossRef citations to date
0
Altmetric
Research Paper

TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection

, , , , , , , , , , , & show all
Pages 1844-1862 | Received 21 Aug 2022, Accepted 21 Dec 2022, Published online: 01 Jan 2023

References

  • Galluzzi L, Baehrecke EH, Ballabio A, et al. Molecular definitions of autophagy and related processes. EMBO J. 2017;36(13):1811–1836.
  • Hansen M, Rubinsztein DC, Walker DW. Autophagy as a promoter of longevity: insights from model organisms. Nat Rev Mol Cell Biol. 2018;19(9):579–593.
  • Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol. 2013;15(7):713–720.
  • Ogawa M, Yoshikawa Y, Mimuro H, et al. Autophagy targeting of Listeria monocytogenes and the bacterial countermeasure. Autophagy. 2011;7(3):310–314.
  • Hamon M, Bierne H, Cossart P. Listeria monocytogenes: a multifaceted model. Nat Rev Microbiol. 2006;4(6):423–434.
  • Birmingham CL, Higgins DE, Brumell JH. Avoiding death by autophagy: interactions of Listeria monocytogenes with the macrophage autophagy system. Autophagy. 2008;4(3):368–371.
  • Py BF, Lipinski MM, Yuan J. Autophagy limits Listeria monocytogenes intracellular growth in the early phase of primary infection. Autophagy. 2007;3(2):117–125.
  • Zhao Z, Fux B, Goodwin M, et al. Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe. 2008;4(5):458–469.
  • Mizushima N, Yoshimori T, Ohsumi Y. The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol. 2011;27(1):107–132.
  • Chiang C, Gack MU. Post-translational control of intracellular pathogen sensing pathways. Trends Immunol. 2017;38(1):39–52.
  • Xie Y, Kang R, Sun X, et al. Posttranslational modification of autophagy-related proteins in macroautophagy. Autophagy. 2015;11(1):28–45.
  • Chen RH, Chen YH, Huang TY. Ubiquitin-mediated regulation of autophagy. J Biomed Sci. 2019;26(1):80.
  • Berndsen CE, Wolberger C. New insights into ubiquitin E3 ligase mechanism. Nat Struct Mol Biol. 2014;21(4):301–307.
  • Zheng N, Shabek N. Ubiquitin ligases: structure, function, and regulation. Annu Rev Biochem. 2017;86(1):129–157.
  • Deshaies RJ, Joazeiro CA. RING domain E3 ubiquitin ligases. Annu Rev Biochem. 2009;78(1):399–434.
  • Goto J, Otaki Y, Watanabe T, et al. The role of HECT-Type E3 ligase in the development of cardiac disease. Int J Mol Sci. 2021;23(1):22.
  • Yang Y, Zhu Y, Zhou S, et al. TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis. EMBO J. 2022;41(14):e109777.
  • Xu C, Feng K, Zhao X, et al. Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination. Autophagy. 2014;10(12):2239–2250.
  • Chakraborty A, Diefenbacher ME, Mylona A, et al. The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. Nat Commun. 2015;6(1):6782.
  • Lu M, Zhu X, Yang Z, et al. E3 ubiquitin ligase tripartite motif 7 positively regulates the TLR4-mediated immune response via its E3 ligase domain in macrophages. Mol Immunol. 2019;109:126–133.
  • Jin J, Lu Z, Wang X, et al. E3 ubiquitin ligase TRIM7 negatively regulates NF-kappa B signaling pathway by degrading p65 in lung cancer. Cell Signal. 2020;69:109543.
  • Zhu L, Qin C, Li T, et al. The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein. Cell Death Differ. 2020;27(6):1819–1831.
  • Zhou C, Zhang Z, Zhu X, et al. N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1. EBioMedicine. 2020;59:102955.
  • Fan W, Mar KB, Sari L, et al. TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity. Cell. 2021;184(13):3410–25 e17.
  • Yang B, Zhang G, Qin X, et al. Negative regulation of RNF90 on RNA virus-triggered antiviral immune responses targeting MAVS. Front Immunol. 2021;12:730483.
  • Yang B, Liu Y, Cui Y, et al. RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation. PLoS Pathog. 2020;16(3):e1008387.
  • Hansen K, Prabakaran T, Laustsen A, et al. Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway. EMBO J. 2014;33(15):1654–1666.
  • Collier JJ, Suomi F, Olahova M, et al. Emerging roles of ATG7 in human health and disease. EMBO Mol Med. 2021;13(12):e14824.
  • Kuang E, Qi J, Ronai Z. Emerging roles of E3 ubiquitin ligases in autophagy. Trends Biochem Sci. 2013;38(9):453–460.
  • Vittal V, Stewart MD, Brzovic PS, et al. Regulating the regulators: recent revelations in the control of E3 ubiquitin ligases. J Biol Chem. 2015;290(35):21244–21251.
  • Park Y, Jin HS, Aki D, et al. The ubiquitin system in immune regulation. Adv Immunol. 2014;124:17–66.
  • Liu X, Wang Q, Chen W, et al. Dynamic regulation of innate immunity by ubiquitin and ubiquitin-like proteins. Cytokine Growth Factor Rev. 2013;24(6):559–570.
  • Zhang W, Tan X, Lin S, et al. CPLM 4.0: an updated database with rich annotations for protein lysine modifications. Nucleic Acids Res. 2022;50(D1):D451–D9.
  • Feng Y, Yao Z, Klionsky DJ. How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy. Trends Cell Biol. 2015;25(6):354–363.
  • Delcour C, Amazit L, Patino LC, et al. ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure. Genet Med. 2019;21(4):930–938.
  • Marinho FV, Benmerzoug S, Oliveira SC, et al. The emerging roles of STING in bacterial infections. Trends Microbiol. 2017;25(11):906–918.
  • Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol. 2001;2(3):211–216.
  • Zheng H, Lu X, Li K, et al. ATG ubiquitination is required for circumsporozoite protein to subvert host innate immunity against rodent malaria liver stage. Front Immunol. 2022;13:815936.
  • Gomes LC, Dikic I. Autophagy in antimicrobial immunity. Mol Cell. 2014;54(2):224–233.
  • Castillo EF, Dekonenko A, Arko-Mensah J, et al. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation. Proc Natl Acad Sci U S A. 2012;109(46):E3168–76.
  • Henault J, Martinez J, Riggs JM, et al. Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. Immunity. 2012;37(6):986–997.
  • Lee HK, Mattei LM, Steinberg BE, et al. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010;32(2):227–239.
  • Mostowy S, Sancho-Shimizu V, Hamon MA, et al. p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways. J Biol Chem. 2011;286:26987–26995.
  • Wang J, Song D, Liu Y, et al. HLA-DMB restricts human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG7 acetylation. Sci Rep. 2017;7(1):14416.
  • Yang B, Wang J, Wang Y, et al. Novel function of Trim44 promotes an antiviral response by stabilizing VISA. J Immunol. 2013;190(7):3613–3619.
  • Wang J, Yang B, Hu Y, et al. Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7. J Immunol. 2013;191(6):3393–3399.
  • Wang Y, Lian Q, Yang B, et al. TRIM30alpha is a negative-feedback regulator of the intracellular DNA and DNA virus-triggered response by targeting STING. PLoS Pathog. 2015;11(6):e1005012.
  • Lou Y, Han M, Liu H, et al. Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection. Cell Mol Immunol. 2020;17(10):1053–1062.
  • Wang J, Kang L, Song D, et al. Ku70 senses HTLV-1 DNA and modulates HTLV-1 replication. J Immunol. 2017;199(7):2475–2482.
  • Yang B, Song D, Liu Y, et al. IFI 16 regulates HTLV −1 replication through promoting HTLV-1 RTI -induced innate immune responses. FEBS Lett. 2018;592(10):1693–1704.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.