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Clinical Toxicology Volume 55, 2017 - Issue 3
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Clinical Research

Acute salicylate poisoning: risk factors for severe outcome

Rachel M. ShivelyMount Sinai Emergency Medicine Residency Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Correspondence[email protected]
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,
Robert S. HoffmanDivision of Medical Toxicology, Ronald O. Pereleman Department of Emergency Medicine, New York University School of Medicine, New York, NY, USA; View further author information
&
Alex F. ManiniDivision of Medical Toxicology, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; ;Department of Emergency Medicine, Elmhurst Hospital Center, New York, NY, USAView further author information
Pages 175-180 | Received 22 Jul 2016, Accepted 02 Dec 2016, Published online: 09 Jan 2017

References

  • Pearlman BL, Gambhir R. Salicylate intoxication: a clinical review. Postgrad Med J. 2009;121:162–168.
  • Mowry JB, Spyker DA, Brooks DE, et al. 2014 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 32nd Annual Report. Clin Toxicol. 2015;53:962–1147.
  • Waseem M. Salicylate toxicity. Medscape [Internet]. 2015 [cited 2016 Jan 4]. Available from: emedicine.medscape.com
  • Anderson RJ, Potts DE, Gabow PA, et al. Unrecognized adult salicylate intoxication. Ann Intern Med. 1976;85:745–748.
  • Done AK. Salicylate intoxication. Significance of measurements of salicylate in blood in cases of acute ingestion. Pediatrics. 1960;26:800–807.
  • Dugandzic RM, Tierney MG, Dickinson GE, et al. Evaluation of the validity of the Done nomogram in the management of acute salicylate intoxication. Ann Emerg Med. 1989;18:1186–1190.
  • Chapman BJ, Proudfoot AT. Adult salicylate poisoning: deaths and outcome in patients with high plasma salicylate concentrations. Q J Med. 1989;72:699–707.
  • Martin T. Fatal salicylate levels can be lower than expected. Clin Toxicol. 2014;52:299.
  • Smolinske S, Temple K, Lada P, et al. Take too (many) ASA and call me from the morgue. Clin Toxicol. 2004;42:724–725.
  • Karsbøl JD, Jørgensen HL, Dalhoff K. Low mortality following salicylic poisoning. Ugeskr Laeger. 2010;172:2541–2546.
  • Heffner JE, Sahn SA. Salicylate-induced pulmonary edema. Clinical features and prognosis. Ann Intern Med. 1981;95:405–409.
  • Manini AF, Nelson LS, Stimmel B, et al. Incidence of adverse cardiovascular events in adults following drug overdose. Acad Emerg Med. 2012;19:843–849.
  • Manini AF, Hoffman RS, Stimmel B, Vlahov D. Clinical risk factors for in-hospital adverse cardiovascular events after acute drug overdose. Acad Emerg Med. 2015;22:500–507.
  • Gilbert EH, Lowenstein SR, Koziol J, et al. Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med. 1996;27:305–308.
  • Basavarajaiah S, Sigston P, Budack K. Severe salicylate poisoning treated conservatively. J R Soc Med. 2004;97:587–588.
  • Gabow PA, Anderson RJ, Potta DE, et al. Acid-base disturbances in the salicylate-intoxicated adult. Arch Intern Med. 1978;138:1481–1484.
  • Lugassy D. Salicylates. In: Hoffman RS, Howland MA, Lewin NA, et al., editors. Goldfrank’s toxicologic emergencies. 10th ed. New York (NY): McGraw-Hill Education; 2015. p. 516–527.
  • Rogers JJ, Heard K. Does age matter? Comparing case fatality rates for selected poisonings reported to U.S. poison centers. Clin Toxicol. 2007;45:705–708.
  • Chien W-C, Lin J-D, Chung C-H, et al. Trends in poisoning hospitalization and mortality in Taiwan, 1999-2008: a retrospective analysis. BMC Public Health. 2011;11:703–711.
  • Clegg A, Young J, Iliffe S, et al. Frailty in elderly people. Lancet. 2013;381:752–762.
  • Morgan J, Furst DE. Implications of drug therapy in the elderly. Clin Rheum Dis. 1986;12:227–244.
  • Karsh J. Adverse reactions and interactions with aspirin. Considerations in the treatment of the elderly patient. Drug Saf. 1990;5:317–327.
  • Manini AF, Kumar A, Olsen D, et al. Utility of serum lactate to predict drug-overdose fatality. Clin Toxicol. 2010;48:730–736.
  • Stolbach AI, Hoffman RS, Nelson LS. Mechanical ventilation was associated with acidemia in a case series of salicylate-poisoned patients. Acad Emerg Med. 2008;15:866–869.
  • Greene SL, Dargan PI, Jones AL. Acute poisoning: understanding 90% of cases in a nutshell. Postgrad Med J. 2015;81:204–216.
  • Herres J, Ryan D, Salzman M. Delayed salicylate toxicity with undetectable initial levels after large-dose aspirin ingestion. Am J Emerg Med. 2009;27:1173.e1–1173.e3.
  • American College of Medical Toxicology. Guidance document: management priorities in salicylate toxicity. J Med Toxicol. 2015;11:149–152.

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