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Clinical Toxicology Volume 56, 2018 - Issue 10
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Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity

Anselm WongMonash Toxicology Unit and Monash Emergency Medicine Service, Monash Health, Clayton, Australia; ;Department of Medicine, Clinical Sciences at Monash Health, Monash University, Clayton, Australia; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-6817-7289View further author information
ORCID Icon,
Benjamin CheungMonash Toxicology Unit and Monash Emergency Medicine Service, Monash Health, Clayton, Australia; View further author information
,
Charlotte NejadCentre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia; ;Department of Molecular and Translational Science, Monash University, Clayton, Victoria, AustraliaView further author information
,
Michael GantierCentre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia; ;Department of Molecular and Translational Science, Monash University, Clayton, Victoria, AustraliaORCID Iconhttp://orcid.org/0000-0003-3740-698XView further author information
ORCID Icon &
Andis GraudinsMonash Toxicology Unit and Monash Emergency Medicine Service, Monash Health, Clayton, Australia; ;Department of Medicine, Clinical Sciences at Monash Health, Monash University, Clayton, Australia; View further author information
Pages 904-906 | Received 28 Jan 2018, Accepted 15 Mar 2018, Published online: 22 Mar 2018

References

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  • Vliegenthart AD, Shaffer JM, Clarke JI, et al. Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury. Sci Rep. 2015;5:22–15501.
  • Dear JW, Clarke JI, Francis B, et al. Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies. Lancet Gastroenterol Hepatol. 2018;3:104–113.

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