505
Views
9
CrossRef citations to date
0
Altmetric
Basic Research

COPD and asthma therapeutics for supportive treatment in organophosphate poisoning

, , &
Pages 644-651 | Received 16 Aug 2018, Accepted 21 Oct 2018, Published online: 30 Jan 2019

References

  • Berlinger J, VX nerve agent used to kill Kim Jong Nam, police say [Internet] [cited 2018 Aug 8] 2017. Available from: https://edition.cnn.com/2017/02/23/asia/kim-jong-nam-vx-nerve-agent/index.html.
  • Organisation for the Prohibition of Chemical Weapons. Report of the OPCW Fact-Finding Mission in Syria regarding an alleged incident in Khan Shaykhun, Syrian Arab Republic April 2017. 2017.
  • John H, van der Schans MJ, Koller M, et al. Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network. Forensic Toxicol. 2018;36:61–71.
  • Eddleston M, Chowdhury FR. Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new. Br J Clin Pharmacol. 2016;81:462–470.
  • Aldridge WN, Reiner E. Enzyme inhibitors as substrates: interactions of esterases with esters of organophosphorus and carbamic acids. (Frontiers of biology; vol. 26). Amsterdam, USA: North-Holland publ. Comp; 1972.
  • Massoulie J, Pezzementi L, Bon S, et al. Molecular and cellular biology of cholinesterases. Prog Neurobiol. 1993;41:31–91.
  • Lee EC. Clinical manifestations of sarin nerve gas exposure. JAMA. 2003;290:659–662.
  • Grob D. The manifestations and treatment of poisoning due to nerve gas and other organic phosphate anticholinesterase compounds. AMA Arch Intern Med. 1956;98:221–239.
  • Marrs TC, Toxicology of organophosphate nerve agents. In: Marrs TC, Maynard RL, Sidell FR, editors Chemical warfare agents: toxicology and treatment. Chichester, UK: John Wiley & Sons, Ltd; 2007; p.191–221.
  • Cannard K. The acute treatment of nerve agent exposure. J Neurol Sci. 2006;249:86–94.
  • Eddleston M, Szinicz L, Eyer P, et al. Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials. QJM. 2002;95:275–283.
  • Buckley NA, Eddleston M, Li Y, et al. Oximes for acute organophosphate pesticide poisoning. Cochrane Database Syst Rev. 2011;2:CD005085.
  • Carletti E, Colletier J-P, Dupeux F, et al. Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation. J Med Chem. 2010;53:4002–4008.
  • Kassa J, Fusek J. The influence of oxime selection on the efficacy of antidotal treatment of soman-poisoned rats. Acta Medica. 2002;45:19–27.
  • Worek F, Eyer P, Aurbek N, et al. Recent advances in evaluation of oxime efficacy in nerve agent poisoning by in vitro analysis. Toxicol Appl Pharmacol. 2007;219:226–234.
  • Worek F, Thiermann H. The value of novel oximes for treatment of poisoning by organophosphorus compounds. Pharmacol Ther. 2013;139:249–259.
  • Chowdhary S, Bhattacharyya R, Banerjee D. Acute organophosphorus poisoning. Clin Chim Acta. 2014;431:66–76.
  • Thiermann H, Steinritz D, Worek F, et al. Atropine maintenance dosage in patients with severe organophosphate pesticide poisoning. Toxicol Lett. 2011;206:77–83.
  • Holzgrabe U, Amici M, de, Mohr K. Allosteric modulators and selective agonists of muscarinic receptors. JMN. 2006;30:165–168.
  • Goldsmith M, Eckstein S, Ashani Y, et al. Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro. Arch Toxicol. 2016;90:2711–2724.
  • Wille T, Neumaier K, Koller M, et al. Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: intraosseous versus intravenous injection. Toxicol Lett. 2016;258:198–206.
  • Seeger T, Eichhorn M, Lindner M, et al. Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro. Toxicology. 2012;294:80–84.
  • Tattersall J, CHAPTER 3. Nicotinic receptors as targets for nerve agent therapy. In: Worek F, Jenner J, Thiermann H, Eds Chemical warfare toxicology. Cambridge, UK: The Royal Society of Chemistry; 2016; p.82–119.
  • Global Initiative for Asthma. Global strategy for asthma management and prevention: Updated 2018. 2018.
  • Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2018 Report. 2018.
  • Chowdhury FR, Rahman MM, Ullah P, et al. Salbutamol in acute organophosphorus insecticide poisoning - a pilotdose-response phase II study. Clin Toxicol. 2018;56:820–827.
  • Herbert J, Thiermann H, Worek F, et al. Precision cut lung slices as test system for candidate therapeutics in organophosphate poisoning. Toxicology. 2017;389:94–100.
  • Cooper PR, Kurten RC, Zhang J, et al. Formoterol and salmeterol induce a similar degree of β2-adrenoceptor tolerance in human small airways but via different mechanisms. Br J Pharmacol. 2011;163:521–532.
  • Delmotte P, Sanderson MJ. Effects of formoterol on contraction and Ca2+ signaling of mouse airway smooth muscle cells. Am J Respir Cell Mol Biol. 2010;42:373–381.
  • Barton AK, Niedorf F, Gruber AD, et al. Pharmacological studies of bronchial constriction inhibited by parasympatholytics and cilomilast using equine precision-cut lung slices. Berl Munch Tierarztl Wochenschr. 2010;123:229–235.
  • Ressmeyer AR, Larsson AK, Vollmer E, et al. Characterisation of guinea pig precision-cut lung slices: comparison with human tissues. Eur Respir J. 2006;28:603–611.
  • Bhattacharya A, Bhargava S, Singh V, et al. Efficacy and safety of ipratropium bromide/salbutamol sulphate administered in a hydrofluoroalkane metered-dose inhaler for the treatment of COPD. COPD. 2016;11:1469–1476.
  • Sechaud R, Machineni S, Tillmann H-C, et al. Pharmacokinetics of glycopyrronium following repeated once-daily inhalation in healthy Chinese subjects. Eur J Drug Metab Pharmacokinet. 2016;41:723–731.
  • Ren S, Sechaud R, Su Z, et al. Pharmacokinetics and safety of indacaterol and glycopyrronium (IND/GLY) following repeated once daily inhalation from a fixed-dose combination in healthy Chinese subjects. CP. 2017;55:147–155.
  • Matera MG, Rinaldi B, Calzetta L, et al. Assessing the viability of long-acting β2-agonists in paediatric asthma patients: a pharmacokinetic/pharmacodynamic perspective. Expert Opin Drug Metab Toxicol. 2017;13:129–136.
  • Lecaillon JB, Kaiser G, Palmisano M, et al. Pharmacokinetics and tolerability of formoterol in healthy volunteers after a single high dose of foradil dry powder inhalation via aerolizer TM. Eur J Clin Pharmacol. 1999;55:131–138.
  • Bartow RA, Brogden RN. Formoterol. An update of its pharmacological properties and therapeutic efficacy in the management of asthma. Drugs. 1998;55:303–322.
  • Wu J, Ding C, Ge Q, et al. Simultaneous determination of ipratropium and salbutamol in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879:3475–3483.
  • Bernstein CA, Waters JH, Torjman MC, et al. Preoperative glycopyrrolate: oral, intramuscular, or intravenous administration. J Clin Anesth. 1996;8:515–518.
  • Travers AH, Jones AP, Camargo CA, et al. Intravenous beta(2)-agonists versus intravenous aminophylline for acute asthma. Cochrane Database Syst Rev. 2012;12:CD010256.
  • Bäckström E, Boger E, Lundqvist A, et al. Lung retention by lysosomal trapping of inhaled drugs can be predicted in vitro with lung slices. J Pharm Sci. 2016;105:3432–3439.
  • Gordon J, Panos RJ. Inhaled albuterol/salbutamol and ipratropium bromide and their combination in the treatment of chronic obstructive pulmonary disease. Expert Opin Drug Metab Toxicol. 2010;6:381–392.
  • Hulse EJ, Davies JOJ, Simpson AJ, et al. Respiratory complications of organophosphorus nerve agent and insecticide poisoning. Implications for respiratory and critical care. Am J Respir Crit Care Med. 2014;190:1342–1354.
  • Robenshtok E, Luria S, Tashma Z, et al. Adverse reaction to atropine and the treatment of organophosphate intoxication. Isr Med Assoc J. 2002;4:535–539.
  • Abedin MJ, Sayeed AA, Basher A, et al. Open-label randomized clinical trial of atropine bolus injection versus incremental boluses plus infusion for organophosphate poisoning in Bangladesh. J Med Toxicol. 2012;8:108–117.
  • Perera PMS, Shahmy S, Gawarammana I, et al. Comparison of two commonly practiced atropinization regimens in acute organophosphorus and carbamate poisoning, doubling doses vs. ad hoc: a prospective observational study. Hum Exp Toxicol. 2008;27:513–518.
  • Connors NJ, Harnett ZH, Hoffman RS. Comparison of current recommended regimens of atropinization in organophosphate poisoning. J Med Toxicol. 2014;10:143–147.
  • Bardin PG, van Eeden SF. Organophosphate poisoning: grading the severity and comparing treatment between atropine and glycopyrrolate. Crit Care Med. 1990;18:956–960.
  • Proakis AG, Harris GB. Comparative penetration of glycopyrrolate and atropine across the blood-brain and placental barriers in anesthetized dogs. Anesthesiology. 1978;48:339–344.
  • Choi PT, Quinonez LG, Cook DJ, et al. The use of glycopyrrolate in a case of intermediate syndrome following acute organophosphate poisoning. Can J Anaesth. 1998;45:337–340.
  • Perrone J, Henretig F, Sims M, et al. A role for ipratropium in chemical terrorism preparedness. Acad Emerg Med. 2003;10:290.
  • Chavez J, Segura P, Vargas MH, et al. Paradoxical effect of salbutamol in a model of acute organophosphates intoxication in guinea pigs: role of substance P release. Am J Physiol Lung Cell Mol Physiol. 2007;292:L915–L923.
  • Segura P, Chávez J, Montaño LM, et al. Identification of mechanisms involved in the acute airway toxicity induced by parathion. Naunyn Schmiedebergs Arch Pharmacol. 1999;360:699–710.
  • Zhang XY, Robinson NE, Wang ZW, et al. Catecholamine affects acetylcholine release in trachea: alpha 2-mediated inhibition and beta 2-mediated augmentation. Am J Physiol. 1995;268:L368–L373.
  • Perkins MW, Wong B, Rodriguez A, et al. Inhalation toxicity of soman vapor in non-anesthetized rats: a preliminary assessment of inhaled bronchodilator or steroid therapy. Chem Biol Interact. 2013;206:452–461.
  • Proskocil BJ, Fryer AD. Beta2-agonist and anticholinergic drugs in the treatment of lung disease. Proc Am Thorac Soc. 2005;2:305–310. discussion 311-2.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.